Oral Delivery of Therapeutic Peptides and Proteins provides a complete overview of the journey scientists pursue to attain protein and peptide oral delivery. Oral delivery of therapeutic peptides and proteins requires deep understanding of the physiological barriers and disruptive approaches to overcome them in an integrated fashion. This book highlights that the physiological challenges are manifold and must be accounted for in addition to overcoming protease inhibition and acid stability issues that are commonly mentioned for this area of research. Primary topics include formulation technologies being adopted for oral delivery of proteins and peptides, modification of actives to make them more suited for oral delivery, animal models and their shortcomings in assessing oral bioavailability, and in vitro models to simulate drug absorption and transport. Academics and industry researchers working in formulation development and researchers and advanced students in biotechnology and pharmacy will find this a useful resource.
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