In Situ Bioavailability and Toxicity of Organic Chemicals in Aquatic Systems

1. Equilibrium Sampling of Hydrophobic Organic Contaminants in Sediments

Gesine Witt, Julia Bachtin, and Sabine Sch輎er

2. Passive Sampling of Waterborne Contaminants

Branislav Vrana, Foppe Smedes, and Kl嫫a Hilscherov?/p>

3. Using Tenax Extractable Concentrations to Determine the Bioavailable Contaminant Fraction in Sediments

Amanda D. Harwood and Samuel A. Nutile

4. Quantifying Bioaccumulation in the Aquatic Environment

Part II: Monitoring of Effects In Situ and Bioassays to Assess the Effects of Complex Environmental Samples

5. In Situ Determination of Genotoxic Effects in Fish Erythrocytes Using Comet and Micronucleus Assays

Paula Suares Rocha, Bj顤n Deutschmann, and Henner Hollert

6. Assessing Adverse Effects of Legacy and Emerging Contaminants in Fish Using Biomarker Analysis and Histopathology in Active Monitoring Scenarios

Amaia Orbea, Eider Bilbao, and Miren P. Cajaraville

7. In Situ Exposure of Aquatic Invertebrates to Detect the Effects of Point and Non-Point Source-Related Chemical Pollution in Aquatic Ecosystems

8. Whole Sediment Toxicity Bioassay to Determine Bioavailability and Effects of Aquatic Contaminants Using Zebrafish Embryos

Sabrina Schiwy, Mirna Velki, and Henner Hollert

9. Nematode-Based Effect Assessment in Freshwater Sediments

Part III: Computational Models for Interspecies Comparison and Extrapolation from the Lab to the Field

10. In Vitro-In Vivo Extrapolation to Predict Bioaccumulation and Toxicity of Chemicals in Fish Using Physiologically-Based Toxicokinetic Models

Julita Stadnicka-Michalak and Kristin Schirmer

11. Cross-Species Extrapolation Using a Simplifed In Vitro Tissue Explant Assay in Fish

Bryanna Eisner, Jon Doering, Shawn Beitel, and Markus Hecker

12. Extrapolation of Laboratory-Measured Effects to Fish Populations in the Field

Charles R.E. Hazlerigg