Nanosized materials possess unique properties because of their sub micrometre size (less than 1 m) and thus find wide array of applications in optics, electronics and biology. In biology they are used for delivery of therapeutics molecules and drugs (nanocarrier), imaging, theranostic and ablation therapy.
A wide range of biotechnological applications are served by recent advances in nano- formulation approaches and design of novel nanocarriers, capable of efficiently delivering biotherapeutic molecules. These nanosized structures are much more efficient than tradition therapies in delivering dugs and other molecules to specific locations in controlled manner, even at much smaller dosage. Conventional pharmaceutical delivery systems are marred with multiple issues like poor specificity, drug resistance induction and toxicity, which severely decreases therapeutic efficiencies. This is where nano-based delivery approach comes to rescue and improve rapid clearance, off -target effects, un-controlled release and toxicity issues.
Nanocarrier based delivery approaches are mostly dedicated to transport chemotherapeutic cargos, composed of colloidal nonentities and possess a high surface area to volume ratio. Apart from delivering therapeutic cargoes Nano formulations are also used for theranostic and ablation therapies. Nano based delivery systems can be broadly categorised as organic nanocomplexes and inorganic nanoparticles-based formulations. These particles allow a great degree of manoeuvrability in terms of their composition (organic, inorganic or hybrid), shape (sphere, rod, multilamellar, hyperbranched etc.), size (small and large), and surface functionalization (PEGylation, targeting moieties, functional groups etc.) as per the specific requirement.
Carbon based nanomaterials which exhibits high cargo loading and biocompatibility are known as organic nanocomplexes and can be used for delivery purposes. Preparation of organic nanocomplexes can be based on self-assembly properties of these molecules (amphiphilic systems), or requires specific synthesis procedure.
Recently much attention is drawn by micelle like nanocomplexes prepared by amphiphilic polymer for drug delivery applications. Also, polymerosome have been reported which shows intracellular microenvironment and tumor responsive properties, which allows triggered payload release (pH, temperature gradient, redox etc.) and improved imaging sensitivity. Poly lactic acid (PLA), saturated poly glycolic acid (PGA), poly a-hydroxy esters, and poly lactic-co-glycolic acid (PLGA) copolymers are FDA approved and most commonly used synthetic polymer for drug delivery applications
外文書商品之書封，為出版社提供之樣本。實際出貨商品，以出版社所提供之現有版本為主。部份書籍，因出版社供應狀況特殊，匯率將依實際狀況做調整。
無庫存之商品，在您完成訂單程序之後，將以空運的方式為你下單調貨。為了縮短等待的時間，建議您將外文書與其他商品分開下單，以獲得最快的取貨速度，平均調貨時間為1~2個月。
為了保護您的權益，「三民網路書店」提供會員七日商品鑑賞期(收到商品為起始日)。
若要辦理退貨，請在商品鑑賞期內寄回，且商品必須是全新狀態與完整包裝(商品、附件、發票、隨貨贈品等)否則恕不接受退貨。
