The local growth and metastatic spread of breast cancer cells is strongly associated to the co-existence of changes in haemostasis. Platelets play a crucial role in the framework of this nterplay, predominantly through their activation and the trend for reactive thrombocytosis, which both lead to the formation of new blood vessels and increase the local and systematic inflammatory profile, favoring the natural progression of breast cancer. Therefore, it would be very useful to evaluate whether the common laboratory platelet indices could be considered as biomarkers of the biological behavior of a type of cancer, which stands as one of the leading causes of death for the female population. Within the framework of our present study, we evaluated the common laboratory indices of platelets - total count (TPC), mean volume (MPV), platelet distribution width (PDW), large platelet cell ratio (LPCR) - both alone and in combination with the total lymphocyte count, in the form of the conventional prognostic biomarker of survival - platelet to lymphocyte ratio (PLR) - as well as in the context of its modified version we propose - large platelet to lymphocyte ratio (LPLR). The laboratory data were evaluated for their degree of correlation with the nature of the underlying neoplasia (benign or malignant neoplasia) and, in the case of malignant lesions they were correlated with the basic pathological-anatomical characteristics -tumor size, spread to lymphatic nodes, grade, over-expression of hormonal receptors/HER2 protein- and the Nottingham Prognostic Index (NPI), score used to estimate the 5-year survival of breast cancer patients.
外文書商品之書封，為出版社提供之樣本。實際出貨商品，以出版社所提供之現有版本為主。部份書籍，因出版社供應狀況特殊，匯率將依實際狀況做調整。
無庫存之商品，在您完成訂單程序之後，將以空運的方式為你下單調貨。為了縮短等待的時間，建議您將外文書與其他商品分開下單，以獲得最快的取貨速度，平均調貨時間為1~2個月。
為了保護您的權益，「三民網路書店」提供會員七日商品鑑賞期(收到商品為起始日)。
若要辦理退貨，請在商品鑑賞期內寄回，且商品必須是全新狀態與完整包裝(商品、附件、發票、隨貨贈品等)否則恕不接受退貨。
