Super Agers：An Evidence-Based Approach to Longevity (The Guardian Best Books of 2025)

The New York Times Bestseller
A Financial Times Book of the Year 2025
A Guardian Book of the Year 2025

A detailed guide to a revolution transforming human longevity -- a breakthrough moment in the history of human health care -- from one of the most respected medical researchers in the world.

‘Fascinating . . . expertly surveys the latest approaches to managing the diseases and decline associated with ageing.’
Financial Times

'Extraordinary . . . a blueprint for the future.'
Siddhartha Mukherjee, author of The Emperor of All Maladies

'A tour de force.'
Venki Ramakrishnan, Nobel Laureate and author of Why We Die

In this breakthrough moment in the history of human health care, Super Agers is an evidenced-based guide to the revolution transforming human longevity. From his unique position as a leader overseeing millions in research funding, Dr Topol explains how you can benefit from new the treatments becoming available at a faster rate than ever, and the fundamental reasons — from semaglutides to AI — that we can be confident these breakthroughs will continue.

More than a quarter of the adult population lives with two or more chronic diseases, with that figure increasing to over half in individuals aged 65 and older. Dr Topol explains the power of the new approaches to the worst chronic killers — diabetes/obesity, heart disease, cancer, and neurodegeneration—and how treatments can begin long before middle age, and even long after. In thirty years, we will have five times as many people at least one hundred years old and they will be healthier than ever because of the breakthroughs Super Agers describes.

These remarkable discoveries are deeply inspiring about our human potential. We can now realistically see how we can make considerable headway for preventing age-related diseases and may one day be able to slow the body-wide aging process itself.

'Imagine a world where diseases once thought incurable are treated, where we are healthier for longer. This future is getting close thanks to a radical convergence of AI and bioscience. In this gripping, vitally important and meticulously researched account, Eric Topol reveals the extraordinary breakthroughs that are transforming medicine—and our lives.'
Mustafa Suleyman, author of The Coming Wave