Renal Fibrosis: Prevention and Treatment

Renal fibrosis is the progressive scarring of the kidneys, often resulting from Chronic Kidney Diseases (CKD). It involves the excessive accumulation of extracellular matrix proteins in the renal tissue, impairing normal kidney function. Various factors such as inflammation, oxidative stress, and tissue injury contribute to its development. Over time, renal fibrosis can lead to kidney dysfunction and ultimately renal failure if left untreated. Common symptoms include reduced urine output, fluid retention, and hypertension. Diagnosis typically involves imaging studies and renal function tests. While current treatments aim to slow its progression and manage symptoms, preventing renal fibrosis requires addressing underlying conditions like diabetes, hypertension, and autoimmune diseases. Research into novel therapies targeting fibrosis pathways offers hope for improved outcomes in managing this debilitating condition. This book includes some of the vital pieces of work being conducted across the world, on various topics related to renal fibrosis. Some of the diverse topics covered in this book address the varied researches under this category. This book is a vital tool for all researching and studying this field.