Structural and Antimicrobial Insights into Thiophene Hydrazones

The global emergence of drug-resistant microbial strains has intensified the search for novel chemical entities with potent antimicrobial properties. In this context, heterocyclic compounds have attracted substantial attention, with thiophene-based scaffolds emerging as promising candidates due to their structural versatility and broad biological activity. Among the various functionalized derivatives, hydrazide-hydrazones of thiophene have shown remarkable pharmacological potential, particularly as antimicrobial agents.This book, Structural and Antimicrobial Insights into Thiophene Hydrazones, is a comprehensive account of the synthesis, structural elucidation, and biological evaluation of a novel series of thiophene derivatives. The work is the culmination of rigorous experimental research, combining classical organic synthesis with modern spectroscopic and microbiological techniques. The derivatives presented in this book have been meticulously characterized using IR, NMR, and CMR spectroscopy, and their antibacterial and antifungal activities have been systematically evaluated through MIC (Minimum Inhibitory Concentration) assays.