Questions regarding the nature and appropriate management of cavernous malformation (CM) have clouded researchers and those faced with making clinical decisions for several decades. CMs may be seen as an incidental finding on MRI studies, or they may present with symptoms, such as seizures or intracranial hemorrhage, often causing severe neurologic deficit. Cavernous Malformations of the Nervous System provides a comprehensive and authoritative review of the current practice in diagnosis and management of these cerebrovascular disorders. Emphasis has been laid on the understanding of basic sciences with chapters committed to understanding of CCM1, 2 and 3 genes and their role in CCM biology, as well as clinical genetics. Controversial topics which continue to pose treatment challenges such as safety of anticoagulation and prophylactic management during pregnancy are also discussed. This book will be of interest to basic science researchers, neurosurgeons and vascular neurologists both
Adult hydrocephalus is an insidious yet treatable condition that develops slowly, with usual onset around 60 years of age. It is poorly recognized and many cases are not diagnosed until late in the course of disease, leading to poorer patient outcomes and a high financial cost to healthcare providers. The resulting neurological symptoms include gait/balance problems, loss of bladder control, and a cognitive decline leading to dementia, which is often mistaken for Alzheimer's disease. This book - the first published on this topic since 1993 - provides comprehensive guidelines to improve the speed and accuracy of diagnosis, and covers various neurosurgical techniques used to treat the disease, including the insertion of different types of shunts and endoscopic third ventriculostomy. This is essential reading for neurologists, neurosurgeons, family physicians, and radiologists who may well encounter adult patients with hydrocephalus more often than they realize.
Lim (neurosurgery, Johns Hopkins U.), Hsu, Rigamonti, and Kleinberg compile 16 chapters on the use of radiosurgery for central nervous system diseases. Neurosurgeons from the US, Canada, and France de
