MicroRNA Interference Technologies

MicroRNAs (miRNAs), endogenous noncoding regulatory mRNAs of around 22-nucleotides long, have rapidly emerged as one of the key governors of the gene expression regulatory program in cells of varying

This volume examines different approaches toward understanding the function of microRNA (miRNA) and the tools used to regulate microRNA expression in nervous systems. MicroRNA Technologies also explor

Emerging technologies such as the Internet and biotechnology have the potential to create new industries and transform existing ones. Incumbent firms, despite their superior resources, often lose out to smaller rivals in developing emerging technologies. Why do these incumbents have so much difficulty with disruptive technologies? How can they anticipate and overcome their handicaps? Wharton on Managing Emerging Technologies presents insights, tools, and frameworks from leading busi-ness thinkers based on the research of Wharton's Emerging Technologies Management Research Program. This pioneering industry-academic partnership, established in 1994, is one of the longest and broadest initiatives on the management of emerging technologies. For the first time, this book distills the insights from the program into a single volume for managers, covering a wide range of issues related to the successful management of emerging technologies. The editors contend that managing emerging technologie

The field of forensic DNA analysis has grown immensely in the past two decades and genotyping of biological samples is now routinely performed in human identification (HID) laboratories. Application areas include paternity testing, forensic casework, family lineage studies, identification of human remains, and DNA databasing. Forensic DNA Analysis: Current Practices and Emerging Technologies explores the fundamental principles and the application of technologies for each aspect of forensic DNA analysis. The book begins by discussing the value of DNA evidence and how to properly recognize, document, collect, and store it. The remaining chapters examine: The most widely adopted methods and the best practices for DNA isolation from forensic biological samples and human remainsStudies carried out on the use of both messenger RNA and small (micro) RNA profilingReal-time polymerase chain reaction (PCR) methods for quantification and assessment of human DNA prior to genotypingCapillary electr

Shortly before his death in 1984, Michel Foucault spoke of an idea for a new book on "technologies of the self." He described it as "composed of different papers about the self...,about the role of re

Explore six renewable energy technologies that are used around the world! Accessible verse and lush illustrations introduce children to important information about how we can harness the planet's natu

In this eye-catching book, readers can explore the hidden inner workings of machines and inventions, from mundane objects such as toasters and bicycles to cutting edge technologies such as pill-sized

Tobias Klein explores applications of 3D printing in architecture, art, design and interactive media installations in order to create a fusion of contemporary CAD/CAM technologies built from natural m

An urban planning expert traces the root of modern, sprawling megacities to advances in information technologies throughout the twentieth century and discusses how these advances can inform and improv

Master alternative Big Data technologies that can do what Hadoop can't: real-time analytics and iterative machine learning. When most technical professionals think of Big Data analytics today, th

The R&D activity in the Information and Communication Technologies (ICT) industrial sectors is an important factor in boosting the competitiveness of the European economy, and it stands high on th

Jules Verne (1828-1905) was internationally famous as the author of novels based on 'extraordinary voyages.' His visionary use of new travel technologies inspired his readers to look to the industrial

Get solid collaboration from team members in remote locations Globalization and new technologies have made team collaboration from distant geographical locations'on the road, from home or cli

Secure Your Systems Using the Latest IT Auditing Techniques Fully updated to cover leading-edge tools and technologies, "IT Auditing: Using Controls to Protect Information Assets, Second Edition, expl

Strauss/Frost offers traditional marketing coverage with a twist: its focus is on the Internet and other technologies that have had a profound effect on marketing. The fifth edition assists all market

The digital divide and the inequalities of the availability and deployment of Information and Communication Technologies (ICTs) between developed and developing countries have long been a source of co

Adamy, author of the Journal of Electronic Defense's popular "EW 101" column, gives engineers, defense contractors, managers, and government procurers a basic knowledge of the technologies and techniq

Examining how the `here and now' of space, territory, the body, are being redefined by new technologies and how this undoes simplistic versions of the globalization thesis, Paul Virilio demonstrates h

The rapid pace of microRNA (miRNA) research continues to drive the advances of techniques for miRNA expression profiling, and innovative technologies that are more sensitive, specific, quantitative, a

A touching, out-of-this-world graphic novel about a daughter, her father, and the aliens that may or may not be speaking to him.Julia didn’t always believe in aliens.It was her father who convinced her otherwise. You see—Julia’s dad believes he was abducted by aliens. And ever since then, he’s been obsessed with the extraterrestrial beings livingout there.So when a festival commemorating the 75th anniversary of the infamous UFO crash in New Mexico rolls around, Julia turns down a dream vacation to Hawaii with her best friend, Sara, to join her dad for a weekend trip to Roswell, where he expects the aliens to make contact.But amid the alien-themed goofiness of the festival, Julia finds she isn’t sure whether her father reallydidget abducted. His memories of alien interference are starting to sound increasingly shaky, and with them, her faith in him. Will this weekend bring the two closer together or only drive them apart?A heartfelt story of family, loyalty, and the lengths we go to sup

"Instantly engaging, constantly suspenseful, ultimately poignant and satisfying. Loved it!"--Diana Gabaldon, author of the #1 New York Times bestselling Outlander seriesWhen fragile, sixteen-year-old Hope Walton loses her mom to an earthquake overseas, her secluded world crumbles. Agreeing to spend the summer in Scotland, Hope discovers that her mother was more than a brilliant academic, but also a member of a secret society of time travelers. And she's alive, though currently trapped in the twelfth century, during the age of Eleanor of Aquitaine. Hope has seventy-two hours to rescue her mother and get back to their own time. Passing through the Dim, Hope enters a brutal medieval world of political intrigue, danger, and violence. A place where any serious interference could alter the very course of history. And when she meets a boy whose face is impossibly familiar, she must decide between her mission and her heart—both of which could leave Hope trapped in the past forever.

Today, artists are able to create using multiple methods of production―from painting to digital technologies to crowdsourcing―some of which would have been unheard of just a few decades ago. Yet, even

Practical OpenCV is a hands-on project book that shows you how to get the best results from OpenCV, the open-source computer vision library.Computer vision is key to technologies like object recogniti

Covering many techniques widely used in research, this book will help researchers in the physical sciences and engineering solve troublesome - and potentially very time consuming - problems in their work. The book deals with technical difficulties that often arise unexpectedly during the use of various common experimental methods, as well as with human error. It provides preventive measures and solutions for such problems, thereby saving valuable time for researchers. Some of the topics covered are: sudden leaks in vacuum systems, electromagnetic interference in electronic instruments, vibrations in sensitive equipment, and bugs in computer software. The book also discusses mistakes in mathematical calculations, and pitfalls in designing and carrying out experiments. Each chapter contains a summary of its key points, to give a quick overview of important potential problems and their solutions in a given area.

The iPad. The Kindle. Twitter. When the Best Technology Writing series was inaugurated in 2005, these technologies did not exist. Now they define our 21st-century lives. As Julian Dibbell writes in hi

Core Insight：Cross-Domain Data Collaboration: Unlocking Chip PotentialEliminating the "efficiency gap" caused by knowledge silos is the starting point for industry potential. Data doesn't lie; Data Science provides the solution: Through innovation and cross-domain restructuring, we visualize results to become the critical accelerator for boosting efficiency.GenAI Reshaping the Future of SemiconductorsFacing the immense challenge of the slowing pace of Moore's Law, the semiconductor industry urgently requires new breakthroughs. This book is specifically designed to solve the "Efficiency Black Hole" that consumes tens of billions of dollars annually in the industry.The Empowering DTCO Innovation with AI and Machine Learning offers readers a practical DTCO.ML Framework, demonstrating how to leverage Machine Learning (ML) and Generative AI (GenAI) technologies to inject new acceleration into chip manufacturing processes. Learn to master process variability and optimize chip energy efficien

A unique illustrated exploration of the development of finance that combines data from every part of the world and covers five thousand years of history “The book is a lot of fun. Data-fixated readers will enjoy unpicking its main content: a series of elegantly produced maps, graphs and other visualisations. These are eclectic in scope and ambitious in intent.”—Jonathan Guthrie, Financial Times From the emergence of money in the ancient world to today’s interconnected landscape of high-frequency trading and cryptocurrency, the story of finance has always taken place on an international stage.Finance is one of the most globalized and networked of human activities, and one of the most important social technologies ever invented. This volume, the first visually based book dedicated to finance, uses graphics and maps to bring the complex and abstract world of finance down to earth, showing how geography is fundamental for understanding finance, and vice versa. It illuminates the people—inc

A bold reinterpretation of economics and history revealing why technology does not inevitably lead to shared prosperity, and how we must redirect innovation in the age of AI to benefit all. A thousand years of history and contemporary evidence make it clear that progress depends on the choices we make about technology. New ways of organizing production and communication can either serve the narrow interests of an elite or become the foundation for widespread prosperity. At no point has this been truer than the crossroads we face today. The transformation of work by digital technologies and AI could make life better for most people, or possibly much worse - depending on the economic, social, and political choices we make. Through powerful, illuminating examples, Daron Acemoglu and Simon Johnson fundamentally change how we see the world. The wealth generated by technological improvements in agriculture during the European Middle Ages was captured by the nobility and used to build grand c

In this open access book, Carlos Montemayor illuminates the development of artificial intelligence (AI) by examining our drive to live a dignified life. He uses the notions of agency and attention to consider our pursuit of what is important. His method shows how the best way to guarantee value alignment between humans and potentially intelligent machines is through attention routines that satisfy similar needs.Setting out a theoretical framework for AI Montemayor acknowledges its legal, moral, and political implications and takes into account how epistemic agency differs from moral agency. Through his insightful comparisons between human and animal intelligence, Montemayor makes it clear why adopting a need-based attention approach justifies a humanitarian framework. This is an urgent, timely argument for developing AI technologies based on international human rights agreements.The ebook editions of this book are available open access under a CC BY-NC-ND 4.0 licence on bloomsburycolle

A playful and deeply affective short story collection about the histories, technologies, and generational divides that shape our relationshipsfrom the award-winning writer ofDays of DistractionCompelling and perceptive,Tomb Sweepingprobes the loyalties we hold: to relatives, to strangers, and to ourselves.In stories set across the US and Asia, Alexandra Chang immerses us in the lives of immigrant families, grocery store employees, expecting parents, and guileless lab assistants.A woman known only to her neighbors as the Asian recycling lady collects bottles from the streets she calls home. A young college grad ponders the void left from a broken friendship. An unfulfilled housewife in Shanghai finds a secret outlet for her ambitions in an undercover gambling den.Two strangers become something more through the bond of mistaken identity.These characters, adeptly attuned to the mystery of living,invite us to consider whether it is possible for anyone to entirely do right by another.Tomb S

From the very beginnings of sound recording, engineers have strived to reproduce the original sound as purely as possible and overcome the noise that technology leaves in recordings. However, this desire denies the fact that technologically mediated sound is always shaped and filtered by the many channels it travels through as it is recorded and reproduced. The noise that each medium inscribes on recorded sound is not just inescapable--it is fundamental to the sonic contours that characterize recorded music. But how exactly do media technologies shape sound and music? And how have they changed what we listen for in music over time? In The Logic of Filtering, author Melle Jan Kromhout develops an extensive media archaeological analysis of the 'noise of sound media' that covers all the disturbances, distortions, and interferences that media add to the sounds they reproduce. Combining theoretical, historical, and technical perspectives on sound media, Kromhout sketches a broad history of

Introduction to Flat Panel Displays describes the fundamental physics and materials of major flat panel display technologies including LED, OLED, LCD, PDP and FED and reflective displays. A reference for graduate students and new entrants to the display industry, the book currently covers the basic science behind each display technology and gives solved problems and homework problems in each chapter to aid self-study. With advancements in this field, there is enough change in the FPD industry to justify a second edition.This book offers the latest information on modern display technology and features new developments in OLED materials including phosphorescent, TTA, and TADF OLEDS, white light OLED and light extraction. It provides key information on blue phase, automotive lighting, quantum-dot enhanced LCDS, device configurations and performance, and LEDs, specifically nitrate-based. Application features include OLED for mobile, TV, light and flexible OLED, and reflective display speci

有效的資料分析、統計與繪圖實用錦囊 “和其它的程式語言書籍相比，我從這本書中學到更多。” ―David Curran Cognitive Engineer at OpenJaw Technologies 本書是《R錦囊妙計》第二版，擴展了更多的內容，使用R快速有效地執行超過275種實用資料分析。R語言提供了統計分析工作所需要的一切工具，但是它的結構可能有點難以掌握。本書彙整精簡、任務導向的錦囊，能

Trapped in a world where magic is powerful and dreams are real, Cole continues his quest in book three of thisNew York Times bestselling “fanciful, action-packed adventure” series (Publishers Weekly, starred review), from the author of the Fablehaven and Beyonders series.Cole Randolph still can’t believe the way his life has been turned inside out. Stuck in a strange land far from home, he found his friend Dalton and has survived the first two kingdoms of the Outskirts. But none of that has prepared him for the magnetic highways and robotic bounty hunters of Zeropolis.Ruled by Abram Trench, the one Grand Shaper who stayed loyal to the evil High King, the government of Zeropolis uses advanced technologies to keep tight control. Luckily, the resistance in Zeropolis is anchored by the Crystal Keepers—a group of young rebels with unique weapons.On the run from the High King’s secret police, Cole and Dalton venture to find more of their lost friends—and help their new friend, Mira, locate h

This volume gives language teachers, software designers, and researchers who wish to use technology in second or foreign language education the information they need to absorb what has been achieved so far and to make sense of it. It is designed to enable the kind of critical reading of a substantial literature that leads to a balanced and detailed knowledge of the field. Chapter by chapter, the book builds, through description, analysis, examples, and discussion, a detailed picture of modern CALL.In this book, the label “CALL” is interpreted broadly to include technology-enhanced language learning, Web-enhanced language learning, and information and communication technologies for language learning. The work is distinguished by its attention to a range of languages rather than just English.The authors first set the scene and introduce major areas of interest and growth in CALL, and then look in depth at seven important dimensions: design, evaluation, computer-mediated communication, th

《microRNA鑒定與功能分析技術》綜合國內外有關microRNA研究的進展，首先介紹了microRNA的發現歷程、生物起源及加工成熟的機制、特征及鑒別等，然後在闡述microRNA作用機制的基礎上，詳細介紹了microRNA的調控機理及其在生理、病理進程中的功能，并著重探討了幾種主要非編碼RNA的區別。隨後，重點介紹microRNA的研究方法，涉及生物信息學分析方法與分子生物學方法，前者包括m

基因科技的未來趨勢是全球關注的焦點精準醫療．個性化健康管理．糧食改良．生物燃料破解如何調控基因，一切都有可能二十世紀中，人類解開了基因遺傳之謎，生物學與醫學研究跟著蓬勃發展。隨著科學技術的不斷更新，關於基因的組成、功能、演化、突變、運用，逐漸揭示於世人眼前。深入探索的下一步，迎來更多的疑問——◎單一個細胞開始的胚胎，如何分化為不同功能的性狀？◎自花授粉的玉米卻出現不同原株的斑點，基因可以自己改變位置嗎？◎作為遺傳訊息的信使的DNA序列，難道真的不可逆？◎環境、毒素等外來因子，是否會影響基因表達？基因是生理功能的總藍圖，基因調控透過DNA轉錄、干擾RNA、蛋白質訊息傳導等方式，負責完成藍圖的施工、建造。科學家發現，為了改變環境而出現的基因調控，是生物能應對不同變化的重要因素。也就是說，基因調控決定了絕大多數生物的生理功能。→既然可以調控，只要找到開關，就能重新剪接、位移、修飾！→細胞療法、基因療法、表觀遺傳療法等創新療法，是未來醫學的新解方！2020年諾貝爾化學獎頒給了發現CRISPR/Cas9的兩位女性科學家，因為這套基因剪刀系統，讓人們有了精準控制基因的能力。2024年的諾貝爾醫學獎的得獎者，則是發現微型核醣核酸（microRNA）在轉錄後基因調控的作用而獲得殊榮。基因科技澈底改變人類對生命的理解和醫療的治療方式，科學家能夠精準解析人類基因組，量身訂做治療方案。成生物學透過編寫基因組建構新的生物系統，解決農業與糧食問題，發揮環境保護與能源生產作用。人工智慧優化基因編輯設計的精確性與效率，讓基因調控領域的應用前景愈加廣闊。隨著人類逐漸具備改變自身基因組的能力，基因科技將面臨生命本質與倫理道德的挑戰。如何在科技進步中保有人性與尊嚴，確保技術與創新的目的為服務全人類，本書將帶領讀者一起了解全球在下一階段的共同願景與課題。本書特色◎詳細介紹基因調控的歷史背景、機制、技術，以及六大超級基因的位置、結構、作用，以及於醫療應用的最新資訊。◎台灣與全球基因科技現況與發展趨勢分析，相關新興領域及市場規模簡介。

本書由 DeepMind 共同創辦人、現任微軟 AI 執行長穆斯塔法・蘇萊曼所撰寫，揭示快速發展的人工智慧與尖端科技，正以前所未有的速度改變人類社會。從量子電腦、DNA 印表機到自主武器、能源革命，這些變革既帶來繁榮，也威脅著全球秩序與人類自由。我們正處於歷史的臨界點，而我們尚未準備好。蘇萊曼提出關鍵問題：「人類該如何駕馭這波浪潮？如何在創新與監控之間找到平衡？」這是一本結合第一線經驗、深刻洞察與道德反思，為這個世代帶來提醒與思考方向。NEW YORK TIMES BESTSELLER • An urgent warning of the unprecedented risks that AI and other fast-developing technologies pose to global order, and how we might contain them while we have the chance—from a co-founder of the pioneering artificial intelligence company DeepMind and current CEO of Microsoft AI“A fascinating, well-written, and important book.”—Yuval Noah Harari“Essential reading.”—Daniel Kahneman“My favorite book on AI.”—Bill Gates, GatesNotesA Best Book of the Year: CNN, Economist, Bloomberg, Politico Playbook, Financial Times, The Guardian, CEO Magazine, Semafor • Winner of the Inc. Non-Obvious Book Award • Finalist for the Porchlight Business Book Award and the Financial Times and Schroders Business Book of the Year AwardWe are approaching a critical thresh

近年來由於國際地緣政治變化、全球供應鏈重組、氣候變遷及超高齡社會趨勢，形成世界經濟的挑戰。同時，生成式人工智慧的興起，也為我國發展新興科技及相關產業帶來新契機。鑒於台灣資源有限，因此需集中資源於具潛力、優勢且符合未來需求的利基技術領域，才能在瞬息萬變的AI新時代中取得競爭優勢。面對全球新興技術日新月異的發展，世界各國積極推動各項新興科技相關之政策與計畫，協助推動國家經濟發展和社會福祉的提升。例如：2024年2月美國更新「關鍵及新興科技清單」(Critical And Emerging Technologies)，指引科技政策方向；2024年2月歐盟亦通過「歐洲戰略技術平台計畫」(Strategic Technologies for Europe Platform, STEP)，重點投入數位與深度科技、清潔和資源、生物科技；韓國依據《國家戰略技術育成特別法》，於2023年年底確立12大國家戰略技術，制定技術發展路徑圖和旗艦專案；中國則將「新質生產力」納入2024年「兩會」的「政府工作報告」中，成為中國大陸未來的新興科技策略方針。值得注意的是，新興技術如人工智慧在近年來發展迅速，各國和企業都在積極投入資源，進行相關技術研發和應用。人工智慧在醫療、金融、製造、零售等多個產業領域，均展示出巨大的潛力，提升了營運效率並創造新的商業模式。台灣作為亞洲科技重鎮，如何掌握此波技術革命的先驅，推動本土產業創新與升級，成為台灣產業創新發展與轉型升級的關鍵課題。本期《台經月刊》將以「聚焦前瞻科技驅動台灣產業創新與成長之策略分析」為主題，深入了解美國、歐盟、中國與韓國等國前瞻科技驅動產業創新與成長的策略做法，以探討AI趨勢浪潮下台灣新興科技發展方向，及其帶動產業創新與成長，鞏固我國在全球科技競爭中維持領先優勢，再創產業經濟發展高峰之策略。

榮獲ANTHEM大獎，入選《金融時報》2024年度最佳好書——《演算法》揭露AI正在悄悄主宰我們的工作與生活。記者Hilke Schellmann深入追蹤演算法如何影響求職、監控員工、甚至預測心理健康。她揭示AI背後的偏見與錯誤，並呼籲人類應奪回對未來的主導權。在這個AI重塑世界的時代，本書是一道警鐘，也是一線希望。ANTHEM AWARD WINNER • NAMED A FINANCIAL TIMES BEST BOOK OF THE YEAR 2024AI is on the brink of dominating our lives, threating our privacy and human future—if we don’t take action now. In The Algorithm, Emmy‑award winning Wall Street Journal and Guardian contributor Hilke Schellmann delivers a shocking and illuminating exposé on one of the most pressing civil rights issues of our time: how AI has quietly, and mostly out of sight, taken over the world of work. Schellmann takes readers on a journalistic detective story, meeting job applicants and employees who have been subjected to these technologies, playing AI-based video games that companies use for hiring, and investigating algorithms that scan our online activity to construct personality profiles— including if we are prone to self -harm. She convinces whistleblowers to share r