Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Discover how one grumpy bird and one optimistic worm become friends in this start to a sweet, giggle-inducing early reader series from Geisel award-winning creator Greg Pizzoli. Earl and Worm have been friends for a very, very long time, but their friendship had a rocky start. Earl is a happy go-lucky bird who plays saxophone to his plants because they love music in the morning. His neighbor Worm, on the other hand...well, Worm is the exact opposite. She would rather read in silence. How will these very different neighbors become the very best of friends? With some sweet lemonade, the right shade of paint, and an unfinished poem, and most of all, sharing a little bit about themselves. Award-winning creator Greg Pizzoli delivers three funny and heartwarming stories that will delight fans of other iconic duos like Elephant and Piggie or Pizza and Taco.

"A sure hit for fans of Joanna Ho and Grace Lin." —BooklistPerfect for fans of Spirited Away, this humorous picture book tells the fantastical tale of one grumpy old man and the creation of Taiwan's first night market.Mr. Chow lives for the night, when the moon is a wok full of simmering oil.Too bad he owns a supermarket and has to wake up very, very early. Mr. Chow hates mornings and so does his store: The shopping carts are sluggish, the front door yawns, and the pomelos roll down the aisle in a sleepy daze. When disaster strikes, Mr. Chow seeks advice from other workers and the similarly buoyant, anthropomorphic buildings they work in. And soon, he discovers that his store doesn't have to be a morning market...it can be a night market!Accompanied by spellbinding art from Yu Ting Cheng, debut author Emily Sun Li crafts a whimsical myth about how the very first Taiwanese night market was created.

An alphabet adventure you WON’T want to miss, from Mo Willems Workshop!From Mo Willems Workshop, the team behind the #1 bestselling Don't Let the Pigeon Drive the Bus!, comes this hilarious and engaging alphabet early-learning concept board book with touch-and-trace features throughout.The Pigeon won't say the ABCs! He has at least 26 reasons and excuses why not! From absolutely no way to zero chance!The Pigeon WON'T Say the ABCs! is part of a collection of original board books featuring the beloved character: The Pigeon.Ideal for babies, toddlers, and fans of the picture book series.

In the long-awaited follow-up to the beloved classic Frindle, a new generation of kids discovers the power of words and imagination - and yes, even screens - to solve a mystery and change their world!"A fitting final work from a master storyteller."--Kirkus ReviewsJosh Willet is a techie, a serious gamer. Which is why Josh and his friends can't stand Mr. N's ELA class; it's a strict no-tech zone. Mr. N makes them write everything out by hand, he won't use a Smartboard, and he's obsessed with some hundred-year-old grammar book. Then Josh discovers a secret; turns out Mr. N's been keeping a lot more than technology from his students! Together with his best friend Vanessa, and using all the computer skills they've got, Josh is determined to solve the mystery of Mr. N's past. And maybe get some screentime back, too? Andrew Clements's final novel is a timely one--about the importance of language, the changes that come along with technology (good and bad), and how sometimes you have to chall

Now completely up to date and featuring a new international author team, Marsh and Martin's Oral Microbiology, 7th Edition, remains the microbiology reference of choice for undergraduate and postgraduate dental students, researchers and a wide range of clinical dental professionals. Using a unique ecological approach, this popular textbook describes the complex relationship between the resident oral microbiome and the host in health and disease, providing a clear set of principles to explain whether the microbiota will have a beneficial or an adverse relationship with the host at a particular site.Explores the biological and clinical significance of the oral microbiota in the form of a biofilm on dental and mucosal surfacesEmphasises current concepts on the aetiology of dental caries and periodontal diseases, and reflects upon the impact that the genomic era has had on the field.Contains a new chapter describing traditional and contemporary (molecular) methods to determine the microbia

Welcome to the Nice Age! Wally is looking for his friend, Wolf. It's time to play hide-and-seek! Come out, come out, wherever you are! A giggle-inducing, unjacketed, lower-priced hardcover picture book about friendship and competition that is perfect for emerging readers by the multiple Geisel Award-winning Corey R. Tabor and illustrator Dalton Webb. For fans of Elephant and Piggie and Narwhal and Jelly.Wolf and Wally are playing hide-and-seek. But hiding is hard for mammoths, and seeking is even harder! Especially when Wolf has a superpower: snow white fur that camouflages perfectly with the snowy Arctic landscape.Will Wally find Wolf? Will Wolf find Wally? And what about Otto the great auk, who discovers his own unique (and silly) hiding spot? Who knows! But there will be sweet treats all around for this sweet group of Ice Age friends.Wally Mammoth: Hide-and-Seek is the second title in a laugh-out-loud funny, comic-inspired series about a group of unforgettable friends--created by fr

In the second installment of this full-color, fantasy adventure series perfect for beginning readers, Gus the Mushroom Dragon discovers a special Mushroom Power!Pick a book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Gus hasn't gotten the hang of his powers yet, and he's feeling a bit down. His best friend Ember tries to cheer him up with a trip to the orchard. On the way, Gus gets an important message from a nearby patch of flowers: the flowers need help! Will Gus figure out how to use his new power to connect with plants? Gus and Ember also meet a new friend along the way!Gus and Ember's adventure is told through five full-color short stories with easy-to-read text throughout, making this book a pe

This scratch activity book is filled with amazing butterflies and inviting patches to scratch. Using the wooden scraper provided, scratch off whole patches to reveal hidden details, or scratch lines and patterns to create your own designs. - Every scratch art page has a facing page of butterfly-themed coloring and puzzles.- Easy and relaxing, with satisfying results guaranteed.- Double-ended wooden scraper tool included.

The story most often commonly told about the Maya involves their spectacular collapse at the height of their civilization in the early ninth century CE. Crops died, disease and malnutrition spread, and scorched earth warfare became common. People lost faith in their governments and moved to the Caribbean coast, the mountains of Guatemala, or further afield. But there is another tale that is equally compelling. One hundred years earlier, a group of kings known as the Snakes created a League and were able to force, cajole, or convince their fellow rulers to work towards common causes. In so doing, they took the first small steps towards something that had never existed in the Maya area: an empire. Blood on the Wind narrates this dramatic episode during the Classic Maya period (250-850 CE). From present-day central Mexico across central America, the League attempted to subdue their enemies and transition to an imperial force. In the heart of the lowlands, they created soaring temples, lux

Top Reading SeriesTop Reading is a six-level reading program that helps young English learners build confidence, fluency, and essential reading skills. Through short, engaging passages and age-appropriate topics, students develop vocabulary, comprehension, and a positive reading habit. Designed for EFL/ESL environments, the series supports steady language growth from beginner to low-intermediate levels (CEFR Pre-A1 to A2+).FeaturesClear six-level progression (Levels 1–6)Structured leveling supports steady growth from CEFR Pre-A1 to A2+.Leveled reading passages (30–210 words)Appropriate text lengths help learners build confidence and reading fluency.Fiction and non-fiction exposure across the seriesLevels 1–3 offer a mix of narrative and informational texts, while Levels 4–6 focus primarily on non-fiction topics in science, history, health, and social studies.Reading skill development (leveled)Students acquire reading abilities progressively across levels.Levels 1–2 build foundationa

Top Reading SeriesTop Reading is a six-level reading program that helps young English learners build confidence, fluency, and essential reading skills. Through short, engaging passages and age-appropriate topics, students develop vocabulary, comprehension, and a positive reading habit. Designed for EFL/ESL environments, the series supports steady language growth from beginner to low-intermediate levels (CEFR Pre-A1 to A2+).FeaturesClear six-level progression (Levels 1–6)Structured leveling supports steady growth from CEFR Pre-A1 to A2+.Leveled reading passages (30–210 words)Appropriate text lengths help learners build confidence and reading fluency.Fiction and non-fiction exposure across the seriesLevels 1–3 offer a mix of narrative and informational texts, while Levels 4–6 focus primarily on non-fiction topics in science, history, health, and social studies.Reading skill development (leveled)Students acquire reading abilities progressively across levels.Levels 1–2 build foundationa

Top Reading SeriesTop Reading is a six-level reading program that helps young English learners build confidence, fluency, and essential reading skills. Through short, engaging passages and age-appropriate topics, students develop vocabulary, comprehension, and a positive reading habit. Designed for EFL/ESL environments, the series supports steady language growth from beginner to low-intermediate levels (CEFR Pre-A1 to A2+).FeaturesClear six-level progression (Levels 1–6)Structured leveling supports steady growth from CEFR Pre-A1 to A2+.Leveled reading passages (30–210 words)Appropriate text lengths help learners build confidence and reading fluency.Fiction and non-fiction exposure across the seriesLevels 1–3 offer a mix of narrative and informational texts, while Levels 4–6 focus primarily on non-fiction topics in science, history, health, and social studies.Reading skill development (leveled)Students acquire reading abilities progressively across levels.Levels 1–2 build foundationa

Top Reading SeriesTop Reading is a six-level reading program that helps young English learners build confidence, fluency, and essential reading skills. Through short, engaging passages and age-appropriate topics, students develop vocabulary, comprehension, and a positive reading habit. Designed for EFL/ESL environments, the series supports steady language growth from beginner to low-intermediate levels (CEFR Pre-A1 to A2+).FeaturesClear six-level progression (Levels 1–6)Structured leveling supports steady growth from CEFR Pre-A1 to A2+.Leveled reading passages (30–210 words)Appropriate text lengths help learners build confidence and reading fluency.Fiction and non-fiction exposure across the seriesLevels 1–3 offer a mix of narrative and informational texts, while Levels 4–6 focus primarily on non-fiction topics in science, history, health, and social studies.Reading skill development (leveled)Students acquire reading abilities progressively across levels.Levels 1–2 build foundationa

Top Reading SeriesTop Reading is a six-level reading program that helps young English learners build confidence, fluency, and essential reading skills. Through short, engaging passages and age-appropriate topics, students develop vocabulary, comprehension, and a positive reading habit. Designed for EFL/ESL environments, the series supports steady language growth from beginner to low-intermediate levels (CEFR Pre-A1 to A2+).FeaturesClear six-level progression (Levels 1–6)Structured leveling supports steady growth from CEFR Pre-A1 to A2+.Leveled reading passages (30–210 words)Appropriate text lengths help learners build confidence and reading fluency.Fiction and non-fiction exposure across the seriesLevels 1–3 offer a mix of narrative and informational texts, while Levels 4–6 focus primarily on non-fiction topics in science, history, health, and social studies.Reading skill development (leveled)Students acquire reading abilities progressively across levels.Levels 1–2 build foundationa

Top Reading SeriesTop Reading is a six-level reading program that helps young English learners build confidence, fluency, and essential reading skills. Through short, engaging passages and age-appropriate topics, students develop vocabulary, comprehension, and a positive reading habit. Designed for EFL/ESL environments, the series supports steady language growth from beginner to low-intermediate levels (CEFR Pre-A1 to A2+).FeaturesClear six-level progression (Levels 1–6)Structured leveling supports steady growth from CEFR Pre-A1 to A2+.Leveled reading passages (30–210 words)Appropriate text lengths help learners build confidence and reading fluency.Fiction and non-fiction exposure across the seriesLevels 1–3 offer a mix of narrative and informational texts, while Levels 4–6 focus primarily on non-fiction topics in science, history, health, and social studies.Reading skill development (leveled)Students acquire reading abilities progressively across levels.Levels 1–2 build foundationa

Top Grammar Series IntroTop Grammar is a six-level grammar series designed for early beginner to intermediate English learners. The series provides a clear and systematic approach to grammar learning, helping learners build a strong foundation and gradually develop more advanced language skills.With easy-to-follow explanations, visual learning support, and carefully structured practice, Top Grammar supports both classroom instruction and independent study. The series is suitable for use as a main textbook or as supplementary material in after-school programs, private institutes, and general English classrooms. By completing the series, learners gain a solid understanding of essential grammar and improve their accuracy and confidence in English communication.Key FeaturesGradual Sentence Production TasksActivities build from controlled practice to guided writing, supporting step-by-step sentence formation. Practice tasks progress in complexity to reinforce understanding and improve accur