Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

｛ 澳洲百萬人氣Podcaster的減躁奇蹟 ｝靠著這7個練習，她走出憂鬱、過勞、生活一團糟的人生低谷聚焦／節奏／儀式感學會清除大腦中的過載思緒，重建一個簡單、有效率，又兼具鬆弛感的完美日常吧！★ 歐美百萬讀者風靡，新冠疫情後最棒的生活模式！重新學會好好過生活，而不再只是拚盡全力地過日子★ 每天最短只要1分鐘，可複製、最實用的「簡單生活對策」All in One：大腦斷捨離原子習慣……and more這本書將幫助你：變得更有耐心、更有彈性、更滿足，而且──更容易感受到生活中，那些突如其來的快樂！布茹珂曾經是一位被工作壓力、孩子尖叫聲追著跑的年輕媽媽，直到憂鬱及過勞找上自己，她才赫然發現：所謂生活，不需要每分每秒全力衝刺，你必須找到方法，「傾斜」（而非平衡）那些「該做的事」與「想做的事」。本書將她長年來改變生活模式的方法，拆解成一個個能輕鬆達成的小步驟，這些建議溫暖、實用且安撫人心──每一個筋疲力竭的人，都能藉由調整日常儀式與生活節奏，創造自己的簡單生活。允許自己放鬆、平靜、滿足、保有餘地：你無法控制生命中的每件事，但你可以慢下來，感受生活中的每一個吉光片羽 你正在晾衣服嗎？ 這個時候，與其思考晚餐的計畫、明天的會議、孩子午睡醒來以後你要做什麼，不妨把注意力放在： ● 濡溼而乾淨的衣物的淸新氣味 ● 手中溼潤的布料帶來的涼爽感 ● 使用曬衣夾時發出的淸脆響聲 ● 陽光是如何照射在衣物纖維上 或者，也許你正在泡茶： ● 想想水在茶壺中被加熱的過程 ● 在將水倒入杯中時，請專心聆聽那慰藉心神的音色 ● 觀察茶葉將水染色，從透明變為淺色，再變為深色 ● 如果加入牛奶，就觀察牛奶與水融合，改變了茶的色彩 ● 如果加入糖，就聆聽那在攪拌之時，湯匙碰撞了茶杯杯身所發出的淸脆聲響 ● 注意熱氣如何輕柔舒緩地上升 當你專注做完一件事、細細品味每一個細節之後…… 請深吸一口氣，回到日常之中。 像這樣，透過賦予一件平凡日常事務「儀式感」（本書第一部分），以及建立早晨、晚間，能因應各種環境變化的「生活節奏」（本書第二部分），就能在不改變既有工作與身分的前提下，創造出更簡單、更滋潤、更Chill的生活模式。 而且你從今天就可以開始！※更多精彩內容，請下滑至【前言】──如何使用這本書？

Learn everything there is to know about the groundbreaking career of one of the greatest soccer players of all time inThe Totally Awesome World of Cristiano Ronaldo!Are you a soccer superfan? Want to dive into the life of a soccer superstar?A part of the Totally Awesome World series for middle-grade readers, this book covers all the major highlights of Cristiano Ronaldo’s career on and off the soccer field. Among discussions of athletic achievements, entrepreneurship, and philanthropy are quizzes, quotes, and illustrations for an engaging guide to the life of this iconic athlete.Cristiano Ronaldo is a five-time FIFA Player of the Year, and the iconic player has won 33 senior trophies in his career. From Real Madrid to Manchester United to his current team Saudi Arabia’s Al-Nassr, Ronaldo has brought his talent and his dedicated fans with him to each team. He brings his all to the soccer field and to various charities, including UNICEF, Save the Children, and his own foundation. Whether

An official Minecraft manga adventure! Peaceful life in a perfectly constructed town bores ten-year-old Nico into mischief. Riding Creepers while they explode is fun and all, but what he really wants is to escape the blocky confines of his home and take his crafting skills on an adventure to the ends of the Overworld. Just how big is the world, anyway, and what could possibly stand in his way? Nico has set off on an adventure to the ends of the Overworld! He now has what every great adventurer needs--an adventuring party. Turns out it's good he has friends with him, because he's about to face a spider larger than his whole party combined!

Chip, the little penguin, tries to get out of swim lessons in this hilarious Level Two I Can Read Comic by Maddie Frost.Chip is starting swim school and he really isn’t looking forward to it.When Mom persuades Chip to go and watch, he bonds with new friend Lucy who has the swimmer shivers too. They enjoy themselves at the side of the pool, but when it’s time for the dance party swim—with bubbles and a disco ball—Chip and Lucy wonder if they’re missing out!Join Chip as he navigates this first-time experience with imagination and humor. This Level Two I Can Read Comics title, by Maddie Frost, is illustrated with comic panels and is perfect for children eager to read on their own.

“Dr. Cohen relinquished his role as president several years ago. Even in the final months of his life, he remained engaged and active, not ready to retire. His final book, ‘Be All You Can Be and Get Ready for the Future,’ is a testament to his enduring contribution.” Minglo Shao, Co-founder of CIAM“Bill’s monthly letter always contributed thoughts that were practical and served as reminders to management artisans.”Len Kwiatkowski, Chairman, Board of Trustees, CIAM“In addition to his record of service, Bill Cohen was a mentor, interpreting the teachings of Peter Drucker by sharing anecdotes that guided his subordinates and students while instilling the values of integrity, courage and resilience.”Ron Fogleman, General, USAF. Retired 15th Chief of StaffThis book is a collection of management essays written by Dr. William A. Cohen, Major General, USAF (Ret.), in the final years of his life. Drawing on his military background, professional experience, and education under Peter F. Drucker a

In this Level Three I Can Read! best friends Iris and Walter go on a highly anticipated class trip to the aquarium.Everyone in Miss Cherry's class is excited about visiting the aquarium. Iris and Walter can't wait to sit together on the bus and see scary sharks, shimmery angelfish, and—best of all—penguins. The aquarium is everything they had hoped for, until Walter gets lost! It's a good thing his best friend, Iris, knows what to do!In the beloved Iris and Walter books, the two friends discover that everything is easier when you have a best friend by your side.This Level 3 I Can Read! is written for independent readers and includes challenging words and more complex themes and stories.

Unleash the Power of Storytelling offers a practical roadmap to crafting and delivering more powerful, persuasive stories that you can use to get more of what you want out of your career and your life.“In this engaging, no-nonsense, and often extremely funny handbook on the craft behind great stories, Rob Biesenbach shares his own storytelling roadmap without hesitation, giving you precisely what you need to raise your business storytelling to an art form."Shonali Burke, ABC, President & CEO, Shonali Burke Consulting"There is no greater skill that will positively impact your career as much as becoming a masterful storyteller. Well-told stories have the power to teach, clarify, and inspire. Rob's experience and unique point of view makes him a go-to authority for ambitious leaders."Patricia Fripp, Past President, National Speakers Association"All the experts suggest you tell stories — but no one tells you how. That's where Unleash the Power of Storytelling comes in. Rob Biesenbach p

★歐巴馬2025年夏季選書★驚悚緊湊、動作十足，極具心理張力，讀來如同動作電影般刺激。★南方氛圍濃厚，火葬場、失落城鎮背景，展現獨特地域與人性的黑暗面。★以深刻描寫家庭創傷與道德選擇聞名的S.A. Cosby，作品屢獲好評。《King of Ashes》是一部扣人心弦的南方犯罪小說，由暢銷作家S. A. Cosby最新力作。故事圍繞一家經營火葬場的家庭——父親車禍意外後陷入昏迷，老大Roman不得不回家，發現弟弟Dante欠下黑幫巨債，姐姐Neveah獨自撐起家業卻身心俱疲。面對殘酷惡勢力，Roman決定以自己的方式救回家人，一場血腥、動盪的家庭復仇劇即將上演——因為，一切都可能付之一炬...A son returning home. A dangerous debt. Secrets about to ignite . . . and a family consumed by flames.Roman Carruthers left the smoke and fire of his family's crematory business behind in his hometown of Jefferson Run, Virginia. He is enjoying a life of shallow excess as a financial adviser in Atlanta until he gets a call from his sister, Neveah, telling him their father is in a coma after a hit-and-run accident.When Roman goes home, he learns the accident may not be what it seems. His brother, Dante, is deeply in debt to dangerous, ruthless criminals. And Roman is willing to do anything to protect his family. Anything.A financial whiz with a head for numbers and a talent for making his clie

In this Level Three I Can Read, meet Iris—the new kid in town—and her soon-to-be best friend, Walter!After a move, Iris is sure that life in her new home will be just awful. There's nothing to do and no one to play with. Iris willneverbe happy here. Then Grandpa suggests a walk. Down the road and around the bend, they discover a huge green tree, a secret hideaway—and a boy named Walter. Maybe life far from the city won't be so lonely after all.In the beloved Iris and Walter books, the two friends discover that everything is easier when you have a best friend by your side.This Level 3 I Can Read! is written for independent readers and includes challenging words and more complex themes and stories.

★ 間諜旅館×祕密任務×校園危機，節奏明快的中階小說冒險新系列★ 密碼破解、防身術、偽裝追蹤一次登場，打造孩子最想入住的間諜世界★ 適合喜歡 Ally Carter、偵探冒險、幽默任務故事的讀者碧雅從小住在間諜祕密旅館，夢想成為母親那樣的頂尖特務，卻被安排去寄宿學校過普通生活。正當她想逃避入學申請，一名神祕女孩住進飯店，危險也悄悄逼近。Raised in a sanctuary hotel for spies, the daughter of one of its top agents is determined to follow in her mother’s footsteps and use her hard-won spy skills to help others in this fun, fast-paced, middle grade series opener.Bea dreams of becoming a spy like her mom. Growing up in the Pangean Hotel, a secret sanctuary for spies, she spends her time studying self-defense, languages, codebreaking, and field medicine, preparing for the day when she can follow in her mother’s footsteps. But her mom has a different plan for Bea: She wants Bea to attend boarding school like one of the normal folk. Bea can’t think of a worse fate, the Life is all she’s ever known. But you do not say no to the Pangean League’s top spy.While Bea is juggling test prep and applications with desperate plans to avoid going to normal school at all c

一起來認識一下「搖滾家族」吧！爸爸是電吉他手、爺爺是主唱、姊姊打鼓、哥哥彈鍵盤還寫歌詞，奶奶跟狗也不落人後，全員都在搖滾樂團裡！除了山姆之外，他們全家走到哪兒，總是穿著閃亮鞋子、蓬鬆搖滾頭，沒錯！這就是「華麗搖滾風」！不過山姆喜歡吹長笛，喜歡寧靜、古典、優雅的音樂，他總覺得自己像是錯頻的電台，完全融不進這個搖滾直拉滿的家庭。眼看學校的期末音樂會就要到了，他最怕的不是吹錯音，而是他的家人能安靜坐著聽完嗎？！但就在舞台恐懼快要把他吞蝕的時候……也許他的搖滾家人們，正是讓他鼓起勇氣在台上演奏完的秘密武器！Sam's family, the Rocks, are too loud for him. But when stage fright hits, maybe his rocking, grooving family is just what he needs.The Rock family make a CRASH wherever they go. It's all a bit much for Sam.Meet the Rocks.Dad is a rock guitarist, Pops is the singer, Liv is the drummer, and Bo is keyboardist and writes the lyrics. Oh, and Nan and the dog are in the band too. It's a household of big shoes, big hair, and GLAM ROCK. Except for the youngest child, Sam. Sam is a flautist who likes peace, quiet and classical music. He doesn't feel like he fits in and he's dreading his end-of-year school recital. Can he trust his family to sit and listen?But when stage fright hits, maybe Sam's rocking, grooving, clanging family might be just what

An exciting activity book with lots of space for fingerprinting.This colourful book is bursting with ideas for fingerprinting lots of summer fun! Create your ideal ice cream, print crabs and fish in a rock pool, decorate a surfboard and print picnic food. There's no need to buy paints or inks, just use the seven bright colours on the inkpad that are attached to the back cover to fill the space with your very own fingerprint pictures.

你是否也曾想改寫故事的結局？可憐的龍龍Dave被困在故事書裡好久好久，每次都卡在黏答答的結局裡！直到小王子George出現，告訴他：文字是可以改寫的——只要夠勇敢！Have you ever wanted to change how a story ends? Then this is the picture book for you! Help! Dragon Dave has been stuck in this book FOREVER. He really wants to get out. The story always has a very sticky ending . . . But when Prince George shows Dave that words can be re-written, will Dave be brave enough to change his story? This funny, innovative picture book is a story of empowerment, friendship, and daring to be different! Written by master storyteller Alex Latimer, author of many picture books, including Pip & Egg Illustrated by new rising talent Phillip Cullen Features important messages, subtly woven into a child-friendly story, with bags of humour and fun Encourages children to be brave, question often, and to embrace change when it feels right

1911年的倫敦港口暗潮洶湧，一隻來自剛果雨林的珍稀小猩猩，成了黑市販子戈萊亞斯與小扒手托夫的牟利工具。12歲的奈蒂意外捲入這場危機，決心阻止這筆交易、拯救這隻無辜生靈。途中她將遇見地底撿骨人、幫派份子與騙徒。這是一段扣人心弦的歷史冒險，也是一場探問勇氣與信任的成長旅程。The much-anticipated thrilling companion to the award-winning When the Sky Falls from best-selling author Phil Earle. It is 1911 and London’s docks thrum with underhand deals, none so great as the arrival of a valuable, rare and exotic animal, smuggled from the depths of the Congolese rainforest. The baby gorilla stands to make one man, the shady Goliath Deeds, very, very rich: he and his right-hand man, juvenile pickpocket, Toff Squabble. Heaven help anyone who dares stand in their way, not least the brave and innocent twelve-year-old Nettie Beecroft, who finds herself embroiled in a dangerous rescue attempt where she encounters toshers, bone grubbers and gangsters. Whom can Nettie trust? And can she save the life of this very special creature? ‘This richly atmospheric adventure . . . confirms Earle as a master of his craft’ Daily Mail ‘Nobody writes

From the author of the instant New York Times bestseller I Hope This Doesn't Find You, Never Thought I'd End Up Here is another hilarious and romantic romcom from Ann Liang, this time following a former model determined to get revenge on the boy who ruined her life.Leah Zhang has spent her whole life in LA - it's all she's ever known. That is until her parents grow tired of her broken Mandarin and zero regard for etiquette, and send her on an intensive two-week travel program across China.There's a competition running throughout the program where the winning duo will receive a glowing letter of recommendation to the college of their dreams. Leah is forced to partner up with her former classmate and least favourite person ever: cynical, sarcastic Cyrus, who's somehow only gotten more annoyingly handsome.But the deeper they wander into China's provinces, the deeper Leah finds herself falling in love - with the boy she thought she despised, the home she never thought she'd call her own, a

The hottest picture book from the incredible duo behind the New York Times bestseller, The Leaf Thief! Squirrel is back, and he's enjoying the long, sunny summer days. But wait! Why is Bird going to bed when the sun is still up? What a silly idea! Squirrel could never fall asleep while it's still light... And when the sun starts to disappear earlier and earlier each night, Squirrel is convinced there MUST be a sun thief about! Join Squirrel on a mission to find the culprit, and meet some new nocturnal friends along the way.Luckily, the sun always comes out in the end ... even if it doesn't stay for long! Another personality-packed story by Alice Hemming, celebrating the changing seasons Brilliant illustrations by Nicola Slater that are full of expression and humour With a handy information spread at the back for kids that explains why days become longer in the summer and get shorter through the winter Lots of fun facts about nocturnal animals, too! Also available: The Leaf Thief (paper

成名後備受追捧的女演員艾莉格拉．布魯克斯，只想逃離聚光燈，於是前往偏遠的寧靜湖參加夏季書展。沒想到才剛抵達，就與冷酷又過分迷人的書店老闆喬納起了衝突，成了鎮上眾人熱議的話題。唯一讓她喘口氣的，是那封封來自神祕書店主的電子信件，幽默、溫柔、讓她心動。她堅信那人絕不會是喬納……但，真的是這樣嗎？這是一場關於在喧鬧世界中找到能做自己的那個人，溫柔又聰明的青春浪漫。今夏最動心的愛情喜劇，等你來翻開。Wish You Were Her, the brand new rivals-to-lovers YA romance from bestselling, award-winning Elle McNicoll, is perfect for fans of Emily Henry's Book Lovers.'A beautiful, witty, cinematic romcom . . . A must read for summer' - Lizzie Huxley-Jones'I loved loved loved this book! My favourite of Elle McNicoll’s yet!' - Reader review'I LOVED this swoony enemies-to-lovers autistic love story' - Rashmi SirdeshpandeDear Mysterious Reader, I think I'm falling in love . . .Everyone wants a piece of actress Allegra Brooks. When she decides she desperately needs to get away from the spotlight she heads for the remote town of Lake Pristine and its summertime book festival.When Allegra immediately clashes with annoying (and annoyingly handsome) bookseller Jonah Thorne, their rivalry soon becomes the talk

Step into Nikki Maxwell's aDORKable world this summer with the BRAND NEW ADVENTURE in the mega-selling Dork Diaries series – now with over 60 million copies in print worldwide! Lately, Nikki’s little sister has been a TOTAL BRAT! But while Brianna is busy raiding her closet and taping a HIDEOUS drawing of Nikki on her bedroom door, Nikki has more important things to think out. It’s the end of summer and she has only 72 hours to completely reinvent herself before starting at Westchester Prep… SQUEEEEEEE!! Nikki is determined to be the COOLEST, CUTEST, SMARTEST, MOST INTRIGUING girl at school. But when disaster strikes and Brianna gets hold of Nikki’s most cherished items… her phone AND her diary, her world is turned upside down.Will an unexpected emergency ruin Nikki’s fabulous start to the new school year or, worse, ruin her relationship with wacky BFFs, Chloe and Zoey, and cute crush Brandon? With a HUGE global fanbase, Dork Diaries is the perfect series for fans of Lottie Brooks, Dia

本書以英國海邊小鎮的中餐外賣店為舞台，描寫Felix與朋友Isaac的第一次偵探行動。從店裡怪事頻傳，到發現一枚神秘銅幣、牽出古老的香港連結，故事不僅有懸疑與幽默，也細膩描寫孩子在友情與競爭中成長的心情。畫風溫暖、節奏明快，是兼具趣味與文化探索的中階小說。Mystery with a side order of friendship!The first in this cosy crime middle-grade series set in a Chinese takeaway, created in partnership with Storymix and author Lui Sit. With black-and-white internal artwork.Felix and his best friend Isaac love mysteries – chasing clues, identifying suspects, catching criminals – they can’t wait to open their own detective agency. So when Felix’s parents’ Lucky House takeaway is cursed with a spate of bad luck, Felix is determined to find the culprit.The boys’ investigations lead them to a clue: an ancient coin with a square hole at its centre. Could this lead them to secret treasure? (Un) fortunately, ‘Nosy’ Nina Ding, Felix’s sworn enemy, may have the answers. While volunteering at the local museum, Nina spotted an old Chinese jewellery box with an indentation in the same shape as the mysterious coin. Does Leighton-on-Sea

地表最壞的大白鵝回來了，但這次他決定當個好鵝！Gordon立志在花園大賽中贏下所有比賽，證明自己最棒——只不過，他的「改過自新」之路好像不太單純……The Meanest Goose on Earth is back! Honkingly funny storytelling from bestselling author Alex Latimer-highly illustrated and full of laughs, this is the perfect series for emerging readers. Gordon is THE MEANEST GOOSE ON EARTH. Well .. . he used to be, but now, he's trying to change his ways and be a GOOD GOOSE.The trouble is, it's really tricky to be kind and patient and good, especially when you've always been mean. In Gordon Wins It All, Gordon decides he wants to be good at EVERYTHING, so he arranges Grover Garden's first-ever GRAND TOURNAMENT. He's determined to win every event and prove he's the best goose around, even if that means cheating with the help of his old friends at the Meanest Goose Society.But will Gordon's selfish scheme be everything he dreamed of? For more mean goose antics read, Gordon Starts a Band.

The second book in the absurdly funny Chronicles of a Lizard Nobody series by multi-award-winning author Patrick Ness.When Daniel arrives at the school bus stop sporting a salmon-coloured hat, Zeke is shocked. Don’t only birds wear hats? As if this isn’t strange enough, the school suddenly has a new student – a fish of all things – and a mysterious new Guidance Counsellor. Meanwhile, Zeke’s friends seem to have ditched him, and even his old nemesis won't give him the time of day. So when somebody melts his house with the Death Ray of Death – twice – Zeke has had enough. Just who is sabotaging his life – and why?

最偉大的小偵探回來了！Bonnie和祖父受邀登上海上慶典船，沒想到夜霧降臨，一聲驚叫後船長離奇死亡，身上滿是疑似海怪留下的傷痕。Bonnie立刻變身為偵探Montgomery Bonbon，展開搞笑又聰明的追查行動！The world's greatest detective is back in the fourth instalment in a brilliantly clever, funny and highly illustrated murder mystery series.Shenanigans are once again afoot in the town of Widdlington, and this time they're on board the Dreadnowt – a galleon ship that’s set to host a fireworks display for the town. Bonnie Montgomery and Grampa Banks are on board as guests, but just after sundown, a fog rolls in and a terrible cry is heard over the crash of the waves. Captain Valancourt stumbles out of the mist, dripping wet and covered in red welts, the like of which a sea monster would leave behind, and is soon pronounced dead by the doctor on board.The crowd is shocked, and Bonnie's fishy-o-meter is off the charts. While Inspector Sands takes over as captain, Bonnie transforms into Montgomery Bonbon, and it’s not long before she’s laid anchor on her prime suspects.Can Montgomery

★ 如果地球是你的作業，結果被人類搞砸了怎麼辦？★ 地球史上最懶外星人登場，爆笑拯救人類計畫！★ 校園幽默 × 外星觀察 × 諷刺喜劇，笑到停不下來外星少女Sky把地球當成自己的學校作業創造出來，但當人類出現後，整個星球開始變得一團糟。為了挽救自己的作品，她只好親自降落地球，試圖修好人類。以外星人的視角觀察人類世界，本書充滿爆笑校園幽默與機智諷刺，是一部輕鬆又聰明的冒險故事。Hilarious observational humour and witty social commentary combine in this debut comedy of an alien reluctantly coming to Earth to "fix" the mess that humans have made of her school project. When alien "Sky" creates planet Earth as part of a school project, she's delighted by her success. Those dinosaurs roaming about the place are top-mark material! Then humans sweep in and it's farewell dinosaurs, hello destruction.This disappointing evolutionary twist calls for drastic measures: Sky, the laziest student in class, is going to have make an effort, go down to Earth and fix humanity...

For bear-lovers and brave hunters everywhere, the classic chant-aloud story by Michael Rosen and Helen Oxenbury is available for young readers as a new interactive board book with easy-to-use pull, slide and play tabs on every page.We're going on a bear hunt. We're going to catch a big one. Will you come too?Join in all the fun of the bear hunt in this ingenious interactive board book for young readers. With super-sturdy tabs to pull, sliders to push and wheels to turn, little fingers will love playing along with the classic story of We're Going on a Bear Hunt, revealing surprises on every page. Entertaining and engaging in equal measure, children can swish swash their way through the long wavy grass; stumble trip through the forest; whirl their way through the swirling snow storm and tiptoe through the gloomy cave to find the bear! Perfect for 2- to 4-year-olds and their grown-ups everywhere.

Genius Kid和Flea這對機智拍檔又回來了！這次他們不處理數學題，也不拯救世界，而是要對付「病毒」這個聽起來很可怕、其實超複雜的東西。從會癱瘓電腦的那種，到一支影片點閱破百萬的「病毒式傳播」，再到讓你立刻請病假的感冒病毒，他們一邊吐槽一邊解釋，用最不正經的方式講出讓人記得住的知識點。本書用漫畫式對話和無厘頭笑點包裝基礎知識，是一本「不小心會學到東西」的讀物。Genius Kid is back with his best friend and neighbour Flea to tackle the humongous subject of . . . VIRUSES!From the techy kind of virus that shut down computer mainframes and brings total panicTo the going viral global fame type of virus (that also creates total panic)To the snotty variety of virus which creates a different sort of Must-go-to-bed now sort of panic . . .Luckily GK and Flea are here to explain everything and nothing at all in the way that only they can! Here's hoping that they go viral too . . .

Meet the noisiest animals in the zoo, with five exciting sounds and a spectacular pop-up surprise at the end.From a roaring tiger to a trumpeting elephant, every animal in the zoo thinks it's the loudest one of all... and they're going to show you why! With hilarious rhyming text and exciting animal noises, this book is full of fun surprises to discover, as all the animals try to outdo each other!

THE INTOXICATING INTERNATIONAL BESTSELLER ABOUT LOVE, COOKING AND MAGIC. PERFECT FOR FANS OF JOANNE HARRIS AND ISABEL ALLENDE.''This magical, mythical, moving story of love, sacrifice and summering sensuality is something I will savour for a long time'' MAUREEN LIPMANLike Water For Chocolate tells the captivating story of the De la Garza family. As the youngest daughter, Tita is forbidden by Mexican tradition to marry. Instead, she pours all of her emotions into her delicious recipes, which she shares with readers along the way. When Tita falls in love with Pedro, he is seduced by the magical food she cooks. Unfortunately, he''s married to her sister...Filled with recipes, longing and bittersweet humour, this charming story of one family''s life in turn-of-the-century Mexico has captivated readers all over the world and was made into an award-winning film.''A joy... Has an energetic charm that''s quite impossible to resist'' LITERARY REVIEW''An epic love story with recipes and a sprink

一起跟恐龍大吼、用力踩踏、享受書中帶來的各種關於恐龍的有趣韻腳吧！和青蛙、貓咪、狗狗一起，投入滿滿的史前韻律歡樂：恐龍、猛獁象，當然還有可愛的史前青蛙大軍登場！由暢銷作家 Kes Gray 和插畫家 Jim Field 聯手打造的《Oi Frog and Friends》系列已累計熱銷超過 300 萬冊！這本押韻趣味繪本絕對可以讓小小恐龍迷們咯咯笑不停。Everyone will want to get their hands on this roaring, stomping, dino-packed new title in the award-winning, bestselling Oi Frog and Friends series.The laughter never ends with Oi Frog and Friends!Get your hands on this roaring, stomping, dino-packed new title in the award-winning, bestselling Oi Frog and Friends series!According to Frog, in dinosaur times sitting down hadn't been invented. So . . .Pterosaurs didn't sit on bendy straws?Velociraptors didn't sit on plug adaptors?And Triceratops didn't sit on lollipops?Join Frog, Cat and Dog for oodles of prehistoric rhyming fun packed with dinosaurs, mammoths and - of course - prehistoric frogs! With over 3 million copies sold across this beloved series, this hilarious new rhyming story from Kes Gray and Jim Field is the perfect picture book to share together. Gu

十歲的 Mayowa 一直覺得爺爺 Edward 很奇怪。他會把鬍子染成翡翠綠，還會偷偷在房間裡跳上書本。直到某一天，Mayowa 也忍不住跳上一本書，才發現這不是胡鬧，而是家族世代相傳的祕密魔法。Mayowa 可以「書本跳躍」。只要跳上一本書，她就能汲取故事中的情緒，再將那些感受注入現實中的人心。一本書裡的勇氣、悲傷、希望與憤怒，都可能成為推動世界改變的力量。當 Mayowa 得知自己的能力也許能拯救許多難民的生命，她決定不再旁觀，而是要真正踏進這場冒險。然而，書本跳躍者不只她和爺爺。有人想用這份力量帶來理解與希望，也有人想把它變成操控人心的工具。Mayowa 必須學會分辨善意與危險，更要明白：故事的力量，從來不只存在於書頁之中。推薦給喜歡《Skandar and the Unicorn Thief》、《Impossible Creatures》與魔法冒險故事的讀者。‘Joyful and truly original’ – Katherine Rundell, author of Impossible CreaturesWARNING: DO NOT JUMP ON THIS BOOK!Have you ever jumped on a book? Perhaps not. Most people would think it was a rather unusual thing to do. Ten-year-old Mayowa has always thought that her Grandpa Edward, who dyes his beard emerald green and jumps on books in private, is rather unusual too.Until one day she jumps on a book for herself, and uncovers a huge family secret …Mayowa can book jump. By jumping on a book, she can harness the emotions inside it and channel them directly into other people. And when the opportunity to use

A guide to everything that biology is about, from things we know, to things we don't know yet.This book explores the fascinating world of biology - the study of all life, from tiny bacteria to plants, animals and entire ecosystems. Discover how living things behave and interact, and the amazing ways they adapt to the world around them. Find out how life on Earth began, how it has changed, and what living things might look like in millennia to come. Take a closer look at cells - the building blocks of life itself - and the vital role they play.Through a mix of diagrams, infographics, comic strips and clear, engaging text, this book shows readers what the study of biology is about, how much it covers, and why YOU might want to study it further yourself. It investigates some of the big issues that biologists are grappling with today, from preventing the spread of ever-evolving diseases to saving animals and plants from extinction.

★結合日記、信件和錄音等多媒體線索，呈現獨特的解謎體驗。★充滿懸疑氣氛的兒童推理小說，適合年輕讀者培養邏輯推理能力。★講述古老謀殺案與現實危機交織，故事張力十足令人欲罷不能。《A Box Full of Murders》是暢銷作家Janice Hallett首次為兒童讀者打造的推理小說，適合喜歡Robin Stevens和Rhian Tracey作品的年輕偵探愛好者。故事講述Ava和Luke在閣樓發現一個裝滿紙張的神祕盒子，裡面藏有信件、日記、報紙剪報和秘密錄音。隨著他們揭開這些線索，發現一宗數十年前未解的謀殺案竟然正在眼前重新展開。兩人決心親自破解謎團，卻愈深入調查，愈發覺兇手仍然在暗處，甚至可能就在他們身邊。讀者同時擁有所有事實與線索，挑戰在主角之前解開真相。'Pure catnip for budding young sleuths' The TelegraphThe first children's murder mystery from number-one-bestselling author of The Appeal, Janice Hallett, perfect for fans of Robin Stevens and Rhian Tracey.When Ava and Luke discover a mysterious box of papers in their attic they are instantly curious about secrets it might hold. As they read through letters, diary entries, newspaper cuttings and listen to secret recordings, they realize that a decades-old, still unsolved, murder mystery is unfolding right in front of them . . .Ava and Luke decide to try and crack the case themselves. But as they work through the clues, it soon becomes clear that the myster

《日文自學ALL IN ONE全攻略【高級】》專為日文自學者量身訂做，只要4步驟，就能一次學好N3-N2程度的日文！只要一本書，就能一次學好日文聽、說、讀、寫！《日文自學ALL IN ONE全攻略【高級】》一次解決日文自學者的五大困境：一、聽得懂簡單句子，但長篇大論就聽得一頭霧水二、面對日本人，聊天總是聊不到心坎裡三、雖然能看懂招牌或傳單等短語，卻無法完整閱讀文章四、可以簡單造句，但要寫出正式的文章卻困難重重五、想要往日檢N2、N1邁進卻信心不足現在，只要仔細並反覆閱讀本書，就能穩固日文基礎、銜接進階學習、準備檢定考試，馬上幫你提升日文能力，聽、說、讀、寫一次學會！《日文自學ALL IN ONE全攻略【高級】》提供7種學習資源、多樣學習方式，就是要你一次學好N3-N2的日文！1. 專為自學者設計、圖文並茂、讓你一看就會的「日文學習課本」　2. 日文名師金子祐己Yumi老師現身教學的15堂「日文文法教學影片【高級】」，時長近70分鐘。3. 日文名師金子祐己Yumi老師現身教學的15堂「日文文法教學影片【中級】」，時長近60分鐘。4. 能運用在訂餐廳、發送商業信件⋯⋯等多種實用場景的50篇日文範文5. 日籍老師親自錄製共140分鐘「日文單字、例句、會話」音檔6. 檢視學習成效的10回「線上測驗」共100題。7. 免費下載、可聽音檔、看文法影片的「Youtor App（內含VRP虛擬點讀筆）」《日文自學ALL IN ONE全攻略【高級】》幫你■ 聽：「不只聽得懂簡單句子，還能進行長篇對話」如果你可以聽懂簡單句子，但聽到比較長篇的對話內容，腦袋就當機了，《日文自學ALL IN ONE全攻略【高級】》是你最好的選擇！用日籍老師獻聲錄製的音檔熟悉語速及語調，練習幾次就能聽懂日本人說什麼！■ 說：「面對日本人，總是聊啊聊不完」已經有一定日文程度的你，想跟日本人聊天時，卻擔心發音不標準或是文法錯誤，所以遲遲開不了口。就用《日文自學ALL IN ONE全攻略【高級】》熟練文法，搭配音檔做跟讀練習吧！讓口腔肌肉熟悉日文發音方式，自信滿滿地把你學習的成果說出口！■ 讀：「不只能看懂招牌或傳單，還能完整閱讀文章」學了那麼久日文，雖然可以看懂簡單的日文短句，但想查詢第一手旅遊資訊，或者喜歡的日本演員發布新劇感想時，才發現自己無法消化更長篇的文章。用《日文自學ALL IN ONE全攻略【高級】

The term "Enlightenment" still carries its tie to a grand philosophical tradition that in Britain moves through Bacon, Locke, and Hume. But the literature and philosophy of the Enlightenment was full of practical knowledge associated with the body and with craft. This book is an account of the eighteenth-century thinkers from across social classes who turned to the body to formulate new ways of knowing natural and social worlds—what Ruth Mack calls handicraft philosophies. The writers discussed in this book include a formerly enslaved man, Olaudah Equiano, and a washerwoman, Mary Collier, as well as gentlemen Joseph Banks and James Boswell, and the artist William Hogarth. In their efforts to communicate embodied ways of knowing, they bring together theory and practice; they set aside objectivity and relish the practical ways of knowing that are traditionally associated with lower classes and less-than-privileged bodies. Mack focuses on how such knowledge proved especially helpful for u

本書為《Cronus Chronicles》三部曲合輯盒裝，以希臘神話為靈感，適合喜愛《Percy Jackson and the Olympians》的讀者。故事從看似零散的異常展開：神祕小貓、忽然現身的表親、以及行蹤可疑的陌生人，逐漸指向一場牽動生死的冒險。Charlotte 與 Zee 為了拯救身邊的人踏入冥界，發現自己握有影響眾人命運的關鍵。隨著危機升級，他們面對海神與古老組織的追擊，只能憑藉友情與機智迎戰。"The perfect series for fans of Rick Riordan's Percy Jackson and the Olympians books." --School Library Journal All three books in the middle grade Cronus Chronicles series, inspired by Greek mythology and perfect for fans of Percy Jackson, available together in one collectible paperback boxed set--now with a new look! Something extraordinary is about to happen to Charlotte Mielswetski. Oh, it's not the cute kitten that appears out of nowhere. It's not the sudden arrival of her cousin Zee, who believes he's the cause of a mysterious sickness that struck his friends in England. And it's not the men in tuxedos who follow Charlotte everywhere. What's so extraordinary is not any one of these things. It's all of them. And when Charlotte's friends also fall sick, Charlotte and Zee set

追尋人類生命的真相，就從佛陀的核心思想開始。兩千六百年前，佛陀領悟到的真諦是什麼？他提倡的根本修習法門有哪些？他的教法又是如何循序漸進地展開呢？達賴喇嘛尊者依循兩大佛教傳統的脈絡，去驗證並宣說佛陀體悟到的究竟真理，無論南傳、北傳或三乘，並非單單是一條宗教之路，而是探尋人類生命實相的旅程，最終，都能帶領我們通往解脫。【本書簡介】世界各地有數億人修持佛教，從西藏的洞穴、東京的寺廟到位於紅木森林內的閉關中心。所有這些佛教傳統都源自兩千六百年前佛陀在印度傳授的教法，這些教法以各種不同的語言在世界各地傳播，使佛教成為今日最具影響力的宗教之一。在本書中，達賴喇嘛尊者和美籍比丘尼圖丹．卻准詳盡地指出兩大佛教運動的異同。這兩大佛教運動分別是北傳佛教，即西藏和東亞的梵文傳統，以及南傳佛教──斯里蘭卡和東南亞的巴利語傳統。全書透過兩大佛教傳統的脈絡，深入思惟佛教的核心教義和修行法門，例如四聖諦、止觀禪修、菩提心和涅槃的意義，以及不同的傳統在詮釋這些修行法門和教義的異同，透過彼此的交互印證與獨一無二的洞見，提供修學者一個更深廣的視野，並且能夠激發滋養各自的知見，掃除通向解脫之道各種以偏概全的障礙。達賴喇嘛尊者說：在過去造作今生之「因」的人，是否和體驗今日之「果」的人相同？我們的痛苦是否是他人的過失？快樂和痛苦是否隨機發生？在心靈的旅程中，這些問題是我們的精神食糧，而我們如何回答這些問題，將影響我們過活的方式。【名人推薦】「那些仔細研讀本書的讀者，將對這些傳統所規畫鋪陳的證悟之道產生深廣的了解。」——菩提（Bodhi）比丘，《佛陀的話語》（In the Buddha’s Words）的譯者「我極力推薦本書，希望每個想要更完整、全面地了解佛教眾多傳統的人，都能受到唯一的導師釋迦牟尼佛的啟發和鼓舞。」——艾倫．華勒士（B. Alan Wallace），《專注力：禪修十階開發心智潛能》（The Attention Revolution: Unlocking The Power of The Focused Mind）的作者「達賴喇嘛尊者和圖丹．卻准悉心地創造了一個及時的獻禮，既令人信服，又充滿智慧。」——喬恩．卡巴金（Jon Kabat-Zinn），《正念療癒力》（Full Catastrophe Living）的作者「這是針對佛教文明所作的無價探勘，佛教的全面歷史、哲理教義、道德戒律、禪修訓練

🎯 資料驅動時代，行銷決策不再靠直覺，你需要的是──科學證據！・折扣真的能提高銷售？哪些顧客即使不推也會買？・無法進行 A/B 測試時，還有哪些方法能推論效果？・在資源有限的情況下，如何讓每一分行銷預算發揮最大效益？✔把抽象的因果推論方法，運用到科技產業的真實商業問題上。✔教你如何思考模型背後的假設與挑戰，搭配實例分析，真正「用得出來」。✔全書以 Python 為實作語言，實務化門檻降低，符合產業主流技術。✔幫助行銷人、資料分析師、產品經理，解決真實業務問題。🚩 最真實的國際讀者讚譽「對數據科學家來說，這本書直接影響我的工作，充滿『恍然大悟』的時刻！」「唯一一本將因果推論從數學理論到Python實作、聚焦產業應用的書！」「適合統計、工程與經濟領域專業人士，完美填補實務缺口！」🚩 來自專家的推薦「Matheus寫的這本書，教導您如何從簡單的模型進展到適用於真實資料，並解決重要實際問題的先進方法，是該主題迄今的最佳著作。」——Sean J. Taylor，Motif Analytics首席科學家「這是一本淺顯易懂的因果推論入門書，聚焦於Python資料分析社群最熟悉的工具和應用場景。」——Nick Huntington-Klein，經濟學教授、《The Effect: An Introduction to Research Design and Causality》作者「少數真正符合科技產業實際需求的因果推論書。每一章都處理實際資料中會遇到的問題，並用 Python 從零實作。推薦給任何希望深入理解並實作因果推論的人。」──D.G. 哥倫比亞大學《工業資料科學》課程講師、Lyft應用科學家每增加一美元的線上行銷預算，能吸引多少新顧客？哪些消費者只有在收到折扣券時才會購買商品？該如何制定最佳定價策略？因果推論提供了一種高效方法，幫助您準確評估各種影響因素對商業指標的改變，而這一切只需幾行簡潔的Python程式碼即可實現。在本書中，作者Matheus Facure深入剖析了因果推論在影響力分析與效果估計上的巨大潛力。無論您是管理人員、資料科學家，還是商業分析師，都將在書中學習到一系列經典的因果推論方法，例如 A/B測試、線性迴歸、傾向分數、合成控制法以及雙重差異法（Difference-in-Differences）。此外，作者也帶您探索現代技術的應用，包括如何利用機

Time to get your toothbrush out—not your hairbrush! Try again, Stitch!Stitch tries and tries again to brush his teeth in this silly, sweet board book perfect for read aloud fun with little ones!Toddlers will love joining their favorite blue alien on his hilariously chaotic journey to master the art of brushing his teeth. With Lilo by his side patiently displaying the correct way to do it, Stitch tries, fumbles, and tries again to get every step right inToothbrushes Are for Teeth.With special features liketextured glitter toothpasteon the cover and asurprise mirrorinside, little ones won't be able to resist smiling along with Lilo and Stitch and showing off their own pearly whites. Arepeated refrainof “Try again, Stitch!” makes this 12-page story perfect for read aloud fun with young children as they start to tackle one of life’s earliest milestones: brushing their teeth!

Expand your knowledge on all things gross with these fun facts about nature’s yuckiest bugs, creatures, and animal habits! Perfect for fans of the Weird But True! series.There’s no escaping gross stuff—especially not in the wilderness! Discover icky, disgusting details about squishy insects, stinky animals, scary plants, and more.From fungi to snails to bats (oh my!), what’s gross has never been so fun!

NEW YORK TIMES BESTSELLER A YALSA BEST FICTION FOR YOUNG ADULTS BOOK OF THE YEAR A BOOKPAGE BEST BOOK OF THE YEARNEW YORK TIMESBESTSELLER • Last year, Nan’s three best friends ventured into the canyons near their small town and never returned. Now one of them is back, and Nan can’t believe it…because she’s the one who killed them. From theNew York Timesbestselling author ofWilder Girlscomes another dark thriller about friendship, jealousy, desire, and revenge, with a twist ending that needs to be talked about.Last summer, Luce, Edie, Jane, and Nan took a boat out for one final swim in the river. It was a perfect summer night.But the only one who returned that night was Nan. Edie, Jane, and Luce disappeared, and Nan’s story has always been the same: She has no idea what happened. The girls went ahead, and it was as though they vanished into thin air.Now, one year later, all of Saltcedar has gathered at the river for a memorial. Nan even recreated the outfit she wore that fateful day las

本書收錄 Jenny Han 的暢銷青春小說《The Summer I Turned Pretty》三部曲，為影集改編版本，附收劇集獨家內容。故事以少女 Belly 每年在 Cousins Beach 與 Fischer 家族共度夏日為背景，編織出一段曖昧與成長交織的青春回憶。她自小暗戀穩重的 Conrad，卻意外發現陽光的 Jeremiah 也對她有情意。一個夏天，她成為兩人情感交錯的中心。這不只是三角戀的故事，更是關於自我發現與選擇的歷程。透過 Jenny Han 細膩的筆觸，每一個夏日片段都映照出青春的猶疑與真摯，是一套能引起共鳴、值得慢慢品讀的成長小說。Now an Original Series on Prime Video!From New York Times bestselling author Jenny Han comes the complete paperback collection of each media tie-in edition of The Summer I Turned Pretty books, featuring exclusive content from the hit streaming series!Belly has always lived for the summertime because it means all her favorite things: swimming, the beach, and the Fischer boys, Conrad and Jeremiah. She has spent every summer with them at Cousins Beach for as long as she can remember. She has always been in love with Conrad and finally, one summer, it seems like he might have feelings for her, too. But it turns out, so does Jeremiah.As the summers go on, Belly has to choose between two brothers who love her as