Pattern Classification Using Ensemble Methods

這本設計精巧的繪本，利用頁頁鏤空的設計，讓畫面在細節與全景之間自由切換——一顆鈕扣、一隻蜜蜂、一盒彩色鉛筆……從小小的元素連結成豐富的世界。文字出自 Émilie Chazerand，以詩意又充滿力量的語句，帶出「群體智慧」與「共同生活」的主題。這是一部溫柔又富象徵性的作品，邀請讀者透過一扇扇小窗，看見「一起」的力量與美麗。Grâce à un système de découpe à chaque page, ce très bel album alterne entre mise en lumière de détails (un bouton, une abeille, des crayons de couleur) et planches foisonnantes.Le tout porté par l'écriture poétique et percutante d'Émilie Chazerand qui aborde une thématique essentielle : l’intelligence collective et le pouvoir du vivre ensemble.Un album tendre avec des petites fenêtres ouvertes sur la force et la beauté d’être ensemble.

The entertaining third installment of this delightful graphic chapter series is bound to get children giggling. Perfect for kids ages 5-8!The Marshmallow Martians have a contest to win on Planet Moop! They need to find the best, biggest, and most unexpected item. They know they can win with something unusual from their favorite planet--Earth! Where do Earthlings keep all of their biggest and coolest items? A museum, of course!This silly graphic chapter book with its ensemble of adorable martians will have kids laughing out loud while gaining confidence in reading. Graphic chapter books serve as a great bridge to graphic novels and longer chapter books.Read all the books in the series!Marshmallow Martians: Show and SmellMarshmallow Martians: Earth SchoolMarshmallow Martians: Museum Sleepover

Following on from the hugely popular Mesozoic Art, this magnificent new volume showcases 20 amazing artists whose work represents the very best of palaeoart. Our knowledge of how dinosaurs and other extinct species looked is continuously evolving with each new palaeontological discovery, as is the dramatic art that depicts these ancient worlds. Palaeoartists now have access to more information than ever before, allowing them to achieve greater levels of accuracy in their work. Using fossilised material and the latest scientific knowledge, palaeoartists visualise and recreate creatures from the prehistoric world - they put flesh on the bones of long-extinct species and their environments. It is through this imaginative artform that fossils can be brought to life in fresh, breathtaking detail. Mesozoic Art II presents 20 new leading paleoartists who present life in the primordial past through a broad diversity of artistic styles and techniques, from traditional oil painting to cutting-ed

A new Little Golden Book based on the Bluey animated series on Disney+ and Disney Junior! Bluey and her family star in this new Little Golden Book based on the Bluey original series, now streaming on Disney+ and Disney Junior. In this storybook, Bluey and Bingo are having lots of fun playing the Magic Xylophone game with Dad, but can they learn to share? Bluey follows the adventures of a lovable and inexhaustible six-year-old Blue Heeler puppy who lives with her Dad, Mum, and four-year-old little sister, Bingo. Along with her friends and family, Bluey enjoys exploring the world and using her imagination to turn everyday life into an amazing adventure. Little Golden Books enjoy nearly 100% consumer recognition. They feature beloved classics, hot licenses, and new original stories . . . the classics of tomorrow.

Playful, interactive, and full of whimsy, Sean Taylor's collection of poems invites little ones to get their fingers, hands, and wiggles ready. One little friendin the playground . . . sliding.Two little friends playing chase and . . . hiding.What better way to get little ones excited about poems than to make them part of the delivery? In the hallowed tradition of nursery rhymes and songs like "Itsy Bitsy Spider," this imaginative collection entices children to use their fingers, hands, and sometimes whole bodies to bring a variety of verses to life. Whether the subject is sailing ships or stomping dinosaurs, falling snow or popping bubbles, jumping onto waterslides or riding a crowded elevator, Sean Taylor's rhythmic read-aloud verses pair with Fiona Woodcock's fresh, colorful illustrations, offering clues to the finger actions kids can follow--unless they're happily acting things out already, using shapes and movements all their own.

A love letter to books, showing how many elements and people contribute to making something beautiful, from Caldecott honoree Elisha Cooper In this poetic and beautifully illustrated ode to creativity and the process of making books, Caldecott honoree Elisha Cooper takes readers on a journey showing how words and art move from one person to another. From writer to reader, and everyone who contributes in between: Here is a book, made with love. An artist's studio overflows with sketches, drafts, a wastebasket, and wonder. A publisher's office hums with computers, layouts, coffee, and teamwork. A printer makes a layout into a book using presses, ink, paper, and time. And that book travels to a school, to a library, to a student, to a home.

Discover over 200 roar-tastic animal facts and reveal amazing hidden pictures!Seek and find incredible animals by lifting the flaps and using the magic card searchlight to discover hidden pictures and learn hundreds of fascinating facts.Friendly andeasy-to-understand textprovides a great introduction to the wild and wonderful world of animals!Featureslift-the-flapsand threemagic searchlightseek and find pages.Includes over200fascinating facts, plus seek-and-find magic searchlight challenges for the reader to discover hidden pictures.From the creators of the bestselling Magic Torch books -"So ingenious you'll wonder why you haven't seen it before." - BookTrust

Where does history come from, and how do we know what really happened? Find out in this eye-opening book.Every nation tells its own history in its own way. This important book explains what's going on behind the scenes in those tellings - who gets to decide which facts are taught, and which truths are massaged, or even denied. Using a mix of comic strips, diagrams and clear, simple language, this book shows readers how to dig deeper into any story, how to investigate recent and ancient history for themselves, and learn why it's vital to understand how the world has ended up where it is today.This is a History book unlike any other you've read. It doesn't just tell stories from the past, it unpicks details within those stories, explains how and where those stories came from, and why they can change, depending on who is telling them.

Discover over 200 jaw-tastic dinosaur facts and reveal amazing hidden pictures!Seek and find incredible dinosaurs by lifting the flaps and using the magic card searchlight to discover hidden prehistoric pictures and learn hundreds of fascinating facts.Friendly andeasy-to-understand, informative textprovides a perfect introduction to the wild and wonderful roar-some world of dinosaurs!Featureslift-the-flapsand threemagic searchlightseek and find pages.Includes over200fascinating facts, plus seek-and-find magic searchlight challenges for the reader to discover hidden pictures.From the creators of the bestselling Magic Torch books -"So ingenious you'll wonder why you haven't seen it before." - BookTrust

Discover over 200 fin-tastic shark facts and reveal amazing hidden pictures!Seek and find incredible sharks by lifting the flaps and using the magic card searchlight to discover hidden pictures and learn hundreds of fascinating factsFriendly andeasy-to-understand, informative textprovides a great introduction to the wild and wonderful underwater world of sharks!Featureslift-the-flapsand threemagic searchlightseek and find pages.Includes over200fascinating facts, plus seek-and-find magic searchlight challenges for the reader to discover hidden pictures.From the creators of the bestselling Magic Torch books -"So ingenious you'll wonder why you haven't seen it before." - BookTrust

This book explores the possibility of building the resilience of the UNESCO cultural landscapes, both using theoretical conceptions and practical strategies and actions. Two case studies have been selected, one in Italy and one in China, which have then been explored for the first time in such a comparative way. Different notions of landscape, as well as the driving force of changes affecting these landscapes, are examined and compared.Moreover, the perceptions of the local communities regarding these landscapes are examined, using online questionnaires with over 400 participants. This research highlights the need for an integrated management system, building stronger rural communities able to manage change and continuity. Five pillars to build the resilience of these landscapes have been provided, with schemes and figures, requiring a people-centered approach in their management.This book demonstrates strong connections between identity and landscape resilience, especially in inlandar

當一對雙胞胎無法就誰的數學更好達成一致時，他們的父親給了他們一個令人困惑的問題。只要一點線索，誰會先找到答案？我是數學明星！系列包括具有挑戰性的數學難題，以故事形式呈現。透過引人入勝的故事情節，並使用各種數學啟發式技巧，逐步描述謎題，然後逐步解決，這些技巧也是世界著名的新加坡數學課程的一部分。透過插圖和引人入勝的故事情節，孩子們將學習數學啟發法，並受到啟發，堅持理解、表現和解決有趣的數學問題！系列特點：根據新加坡數學課程的規定，學習使用數學啟發法解決數學難題每本書都包含由 Yeap Ban Har 撰寫的解決問題指南When a pair of twins cannot agree on who is better in Maths, their father sets them a baffling problem. With just a few clues, who will find the answer first?The I'm a Maths Star! series comprises challenging Maths puzzles, presented in story form. Puzzles are described and then solved, step-by-step, through an engaging storyline, and using various Maths heuristic techniques that are also taught as part of the world-renowned Singapore Maths curriculum. Through illustrations and an engaging storyline, children will learn Maths heuristics, and be inspired to persevere in understanding, representing, and solving fun and intriguing Maths problems!Series features:Learn to solve difficult Maths problems using Maths heuristics, as ident

This jam-packed collection of fun and simple science experiments for kids is perfect for the classroom or home. Stir up some sticky slime, build a solar system with rubber bands, power a speed boat using soap, and construct an erupting volcano, all with Home Activity Lab, which offers exciting experiments for budding scientists. Including a foreword by Professor Robert Winston, this stunning book includes 28 brilliant science projects using simple step-by-step instructions, everyday ingredients that can be found around the house, and amazing photography to guide you from start to finish. Each experiment describes the science behind the project, highlighting STEM facts with STEM icons pointing out the key science, technology, engineering, and math learning involved in each project. "Take it further" panels encourage young readers to experiment and take their projects to the next level, developing their independence, initiative, and creative thinking skills. Perfect for budding scientist

用自己的水瓶、關燈、重複利用舊衣服——原來保護地球可以這麼簡單！《10 Things I Can Do to Help My World》以互動翻頁設計，介紹10個孩子每天都能做到的小行動。插圖鮮明大方，語言簡單親切，不僅鼓勵幼兒主動參與環保，也為親子共讀帶來溫暖啟發。這是一本讓行動從閱讀開始的環保入門繪本。Sometimes it's the little things that make a difference--like filling up your reusable water bottle, upcycling old clothes, or any of the other clever suggestions in this eco-picture book with fun die-cut pages and flaps. Do you bring leftovers for lunch? Or shop for fresh, unpackaged produce at the farmers' market? Perhaps you opt for a bamboo toothbrush over a plastic one, or take public transportation when you go out? Creativity plays a part, too--in crafty projects like using an eggshell as a little container to grow watercress, or making a wildlife shelter in your backyard. With ten doable suggestions, bright illustrations, and short explanations of how the actions help to protect the earth, Melanie Walsh shows even the youngest eco-warriors several easy ways to weave green choices into their everyday lives.

Who says you need lessons to start making music? With The Story Orchestra: I Can Play: Swan Lake, every child can be the star of the show. Discover the enchanting world of Swan Lake in this interactive musical storybook – just press the keys to play Tchaikovsky’s spellbinding score!The Story Orchestra: I Can Play: Swan Lake invites children to step into the story and make the music themselves – no lessons needed, just a sense of fun. With a built-in keyboard that sounds just like a piano and colour-coded notes on every page, children can play along as they follow the scenes from Tchaikovsky’s magical ballet.Using a simple one-finger method, budding musicians can learn 8 short, memorable melodies from Swan Lake, building confidence as they go. With a clear colour and letter-coded system, even the youngest players can follow along independently. And when they’re ready, there’s space to get creative and compose their own tunes using the full 14-key piano.This interactive musical book brin

From a bestselling and award-winning team comes a moving, gorgeously illustrated picture-book biography of one of the greatest cellists of all time, Yo-Yo Ma, and his lifelong passion for using music to unite people in harmony and joy "I've been asking myself all my life, 'What is the purpose of music?'" -Yo-Yo Ma At a young age, Yo-Yo Ma discovered a remarkable gift for the cello, playing Bach from memory by age four. His technique was far beyond his years, but even as he grew and became a world-class musician--studying at Juilliard, performing at Carnegie Hall at a young age, even playing on television before the president of the United States--he wanted to use his gift for something deeper, something bigger. As he asked question after question, trying to understand his place in the world, he discovered something that every culture has in common: music. Ma decided that he would spend his life not only performing for others, but learning from other cultures' musical traditions and fin

《時代週刊》盛讚：「天作之合的繪本組合！」這部由兩位童書界超級明星Quentin Blake與Emma Chichester Clark聯手創作的幽默繪本，對每一位閱讀的孩子來說，將是一個的完美禮物莉莉安娜力大無窮，但她從不炫耀，總是在別人需要的時候，悄悄出手相助。她能一個人把卡在泥巴裡的大毛牛拉出來，也能輕鬆攔住衝過頭的壓路機，甚至還能把一整隻擱淺的大鯨魚丟回大海——對她來說，這些都只是日常小任務...'A match made in picture-book heaven' – The TimesThis brilliantly funny collaboration between two superstar creators about a tiny girl with superhuman strength has all the hallmarks of a future classic.Liliana wears her super power lightly, using it to help others in a crisis. A resilient child, she thinks nothing of singlehandedly rescuing a highland cow stuck in the mud, or of stopping an out-of-control steamroller in its tracks, or of throwing a beached whale back out to sea.With beautiful, detailed, humorous illustrations by the award-winning Emma Chichester Clark, Liliana the Strong is the perfect gift for any child who needs a little reminder that everything will be okay.

Jeffrey Brown brings his irresistible comic spin to the X-Men, one of the most beloved and popular teams of the Marvel Universe.Welcome to Xavier’s School for Gifted Youngsters, where Professor X has his hands full supervising an unruly gaggle of elementary school aged mutants! From the creator of Thor and Loki: Midgard Family Mayhem and the bestselling Darth Vader and Son series, this fun collection sees Wolverine using his claws to roast marshmallows, Nightcrawler playing teleport tag, Danger Room practice hijinks, babysitting duty with the New Mutants, Magneto as a surprise substitute teacher, young Cyclops and Phoenix as sweethearts, Sentinels turned into playground equipment, and much more. Full of warm humor and inside jokes hatched from true fandom, Jeffrey Brown’s adorable interpretations of a classic era for the team will delight fans of all ages.© 2024 MARVELPerfect for:Kids and grown-up Marvel fans alikeFamilies who enjoy sharing funny booksSchool libraries and teacher appre

For fans of I'm Not Scared, You're Scared, comes a hilarious picture book about using humor to combat fear, from actor and director Ben Falcone.It's time for bed, but Claire can't fall asleep. There's a storm outside, and the thunder is so loud and scary! Good thing her parents are there to help. They tell Claire there's no reason to be afraid. After all, there are plenty of things that are scarier than thunder...like a scorpion named Finn who plays the violin! A snake with big fangs and uneven bangs! And a dragon named Rance with ants in his pants! The hilarious list gets more and more outsized, building on itself in the most outrageous ways possible, until Claire is giggling herself right to sleep.Actor/Director/Writer Ben Falcone delivers a delightfully silly story—brought to bouncy life by Kevin Cornell—that reminds us that sometimes a good belly laugh is just the thing you need.

2025 School Library Journal Best Book of the YearFrom the bestselling and award-winning creator of They All Saw a Cat comes a bold and playful exploration of how the sun touches all life on earth--perfect for celebrating Earth Day! Good golden sun, there is much we'd like to know! Are you happy? Are you lonely? Are you feeling well today? Does your belly ever ache? Won't you come down to play? From sunbeam, to flower, to insect, to animal, to plant, to soil, and the earth itself...the sun makes, moves, and transforms life all around us. Celebrate the mysteries of light from sunup to sundown as it weaves its way through creation inspiring change, hope, wonder, and curiosity. Using a bold, young collage-style art perfect for fans of Eric Carle, Brendan Wenzel's mastery of visual storytelling is on full display in this ebullient exploration of the life-giving power of our nearest star.

A hilarious introduction to the mystery genre, starring a boy, his fish, and a whiskered detective in disguise. A little boy's aquarium has been attacked, and his poor fish is terrified! Who could be behind this horrible crime? Never fear: Ramon Fellini is on the case! This brave dog has donned his cleverest cat costume in order to track down the culprit. How does Fellini know a cat is to blame? Why does he say strange things like "Does this house have any other fish?" No time for such questions--Fellini is about to reveal the truth! Unless the ace detective has a different agenda in mind... With dramatic colors, ironic humor, and plenty of clues to discover in the art, this whodunit is a laugh-out-loud read for pet lovers. Children will love using their own sleuthing skills to solve the mystery and predict what Detective Ramon Fellini does next."A hilarious intro to mysteries and a great read aloud."—Betsy Bird, A Fuse #8 Production (a School Library Journal blog)"It reminded me of Kl

In this stunning debut novel, a young Indian man comes to England determined to learn British law so he can use it to help the independence movement back home—but the insidiousness of colonialism as well as a sexual awakening get in his way.Shiv Advani is an eighteen-year-old growing up in India. But he is no ordinary young man. Shiv has been personally chosen by Mahatma Gandhi to come to England, learn their bill of rights, and then return home and help drive the British out of India using their own laws against them. Before he leaves, his family insists he fulfill his arranged marriage and is hastily betrothed to a young woman he hardly knows.He arrives in London in 1931. He is not dressed for the British rain, and, shivering, rings the doorbell of the people who have agreed to host him in this strange land. He finds that his benefactors are having a party and warmly welcome him. He is the only brown person in the room and made acutely aware of his differences. By the end of the even

Learn all about the fascinating world of insects--from bees, to butterflies, beetles, and more. Grab your magnifying glass and head out to discover all about insects-- their different types, body structures, and behaviors. Filled with eye-catching images and bite-sized information, every young nature enthusiast will marvel at the mind-boggling facts about these adaptable creatures. The book covers the seven major insect groups and includes profiles for more than 40 amazing insects, such as the stag beetle, monarch butterfly, and honeybee. Dive into their brilliant world and learn how some insects blend in with their surroundings. Discover how some can survive in different environments, while others can defend themselves against predators using clever tactics. Explore the many ways in which insects help humans, and the crucial role they play in pollination and maintaining a balance in the ecosystem. My Book of Bugs is a wonderful introduction to insects and their many incredible feature

From former UK Children's Laureate Joseph Coelho comes an extraordinary collection of tales--each one illustrated by a different artist, and each just ten words long. Is it possible to tell a tale of love using just ten words? The answer is an enthusiastic yes. And when those words are joined by illustrations from twenty top creators, the results can be stunning. In this unique compendium designed to spark the imagination, Joseph Coelho brings us cherished moments between siblings, worlds where nature blooms and heals, touching tales of beloved pets, and more. Each ten-word tale has been paired with one of the finest illustrators working today, among them Jon Klassen, Jarvis, Bob Graham, Myo Yim, Victoria Turnbull, and Ken Wilson-Max. Together the words and pictures set up a space for creativity as young readers imagine how the story might unravel--and are inspired to pen a ten-word tiny tale of their own. Prefaced by a note from the author, and with two creative writing challenges at

From Hervé Tullet, author of the New York Times bestseller Press Here, a picture book to unleash children’s creativity: Using only a finger and a great deal of imagination, Hervé empowers readers to create a simple flower . . . an entire garden . . . and even whole new worlds!Once again, Hervé Tullet brilliantly and successfully coaxes children to recognize and celebrate their innate artistic talent. He convinces each reader that their hand is magic and capable of transforming a few simple lines, squiggles, dots, and shapes into . . . well, pretty much anything they can imagine!A new Hervé picture book is always a cause for celebration. This is his first in seven years and a companion to Press Here, Mix It Up!, and Let’s Play! with all the hallmark whimsy and imagination that will delight his many fans. Whether enjoyed in a family living room, a kindergarten reading nook, or a preschool art class, there’s something here to enchant every reader.AN INVITATION TO PLAY, EXPLORE, AND LEARN:

美樂蒂是個勤奮的好學生。每個人都認為她在即將到來的考試中會表現得很好，但每天晚上考試前，一個巨大的考試怪物都會出現在她的噩夢中！美樂蒂能否應對自如，還是注定會一再失敗？《我很健康》系列由兒童圖畫書組成，旨在解決當今兒童面臨的緊迫問題，正如新加坡心理健康研究所兒童指導診所的醫療保健專業人員所指出的那樣。每本書都藉鑒了精神科醫生、心理學家和諮商師的經驗，他們為無數兒童提供了從數位成癮到飲食失調等各種問題的諮商。每本書都採用基於故事的方法，包含一個相關的故事，幫助孩子更了解自己，並能夠採取實際步驟來成長、發展和改變。這些書可供學校的教育工作者、諮詢課程中的輔導員和醫生以及幫助孩子應對情緒和掙扎的父母使用。在本系列中：引人入勝的基於故事的方法由經驗豐富的專家撰寫包括給家長和教育工作者的提示和建議Melody is a good and hardworking student. Everyone thinks she will do just fine in her upcoming exams, but each night before an exam, a mega exam monster visits her nightmares! Can Melody cope, or is she doomed to fail again and again?The I Am Healthy series comprises children's picture books that tackle pressing issues facing children today, as identified by healthcare professionals from the Child Guidance Clinic, Institute of Mental Health, Singapore. Each book draws from the experiences of psychiatrists, psychologists and counsellors who have counselled countless children regarding everything from digital addiction to eating disorders. Using

溫柔和仁慈的規則在 Leo利奧 和 Layla萊拉 的家庭中發揮著重要作用。但有一天，利奧和萊拉的媽媽和爸爸開始違反這些規則。利奧和萊拉會做什麼？誰能幫助他們再次感到安全？《我很健康》系列由兒童圖畫書組成，旨在解決當今兒童面臨的緊迫問題，正如新加坡心理健康研究所兒童指導診所的醫療保健專業人員所指出的那樣。每本書都藉鑒了精神科醫生、心理學家和諮商師的經驗，他們為無數兒童提供了從數位成癮到飲食失調等各種問題的諮商。每本書都採用基於故事的方法，包含一個相關的故事，幫助孩子更了解自己，並能夠採取實際步驟來成長、發展和改變。這些書可供學校的教育工作者、諮詢課程中的輔導員和醫生以及幫助孩子應對情緒和掙扎的父母使用。在本系列中：引人入勝的基於故事的方法由經驗豐富的專家撰寫包括給家長和教育工作者的提示和建議Rules of gentleness and kindness play an important role in Leo and Layla's family. But one day, Leo and Layla's Mummy and Daddy start breaking these rules. What will Leo and Layla do? Who will help them feel safe again?The I Am Healthy series comprises children's picture books that tackle pressing issues facing children today, as identified by healthcare professionals from the Child Guidance Clinic, Institute of Mental Health, Singapore. Each book draws from the experiences of psychiatrists, psychologists and counsellors who have counselled countless children regarding everything from digital addiction to eating disorders. Using a story-based

一位老師在畢業聚會上給她的小學六年級學生最後一個要解決的問題。學生能否齊心協力找出答案並圓滿結束最後一年的學習呢？我是數學明星！系列包括具有挑戰性的數學難題，以故事形式呈現。透過引人入勝的故事情節，並使用各種數學啟發式技巧，逐步描述謎題，然後逐步解決，這些技巧也是世界著名的新加坡數學課程的一部分。透過插圖和引人入勝的故事情節，孩子們將學習數學啟發法，並受到啟發，堅持理解、表現和解決有趣的數學問題！系列特點：根據新加坡數學課程的規定，學習使用數學啟發法解決數學難題每本書都包含由 Yeap Ban Har 撰寫的解決問題指南A teacher gives her Primary 6 class one last problem to solve during their graduation party. Can the pupils work together to figure out the answer and end their final year with a bang?The I'm a Maths Star! series comprises challenging Maths puzzles, presented in story form. Puzzles are described and then solved, step-by-step, through an engaging storyline, and using various Maths heuristic techniques that are also taught as part of the world-renowned Singapore Maths curriculum. Through illustrations and an engaging storyline, children will learn Maths heuristics, and be inspired to persevere in understanding, representing, and solving fun and intriguing Maths problems!Series features:Learn to solve difficult Maths problems usin

作為訓練的一部分，一名年輕的弟子受到老師的挑戰，要求他在沒有任何測量工具的情況下找到碗的直徑。他能有辦法在晚餐前找到答案嗎？我是數學明星！系列包括具有挑戰性的數學難題，以故事形式呈現。透過引人入勝的故事情節，並使用各種數學啟發式技巧，逐步描述謎題，然後逐步解決，這些技巧也是世界著名的新加坡數學課程的一部分。透過插圖和引人入勝的故事情節，孩子們將學習數學啟發法，並受到啟發，堅持理解、表現和解決有趣的數學問題！系列特點：根據新加坡數學課程的規定，學習使用數學啟發法解決數學難題每本書都包含由 Yeap Ban Har 撰寫的解決問題指南As part of his training, a young disciple is challenged by his master to find the diameter of a bowl — but without any measuring tools. Can he find a way to obtain the answer before dinnertime?The I'm a Maths Star! series comprises challenging Maths puzzles, presented in story form. Puzzles are described and then solved, step-by-step, through an engaging storyline, and using various Maths heuristic techniques that are also taught as part of the world-renowned Singapore Maths curriculum. Through illustrations and an engaging storyline, children will learn Maths heuristics, and be inspired to persevere in understanding, representing, and solving fun and intriguing Maths problems!Series features:Learn to solve difficult Maths

This second edition volume brings together some of the best experts in the field of modern metabolomics to discuss the latest various techniques used to study specific metabolite classes, and metabolomics in bacterial and mammalian systems. The chapters in this book cover topics such as handling big data for metabolite identification and quantification, as well as building pathways for comparison with other omes, Isotopic Ratio Outlier Analysis (IROA) for quantitative analysis; cholesterol and derivatives in ocular tissues using LC-MS/MS methods; microbial metabolites analysis by mass spectrometry; the metabolomic study of tissues in different diseases; and NMR analysis in livestock metabolomics. It also includes several chapters on the emerging area of spatial metabolomics. Written in the highly successful Methods in Molecular Biology series format, the chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily repro

This 5th edition of this popular graduate textbook, presents a balanced and comprehensive treatment of both time and frequency domain methods with accompanying theory. It includes numerous examples using nontrivial data illustrate solutions to problems such as discovering natural and anthropogenic climate change, evaluating pain perception experiments using functional magnetic resonance imaging, and monitoring a nuclear test ban treaty. The R package 'astsa' has had major updates and the text will reflect those updates. In general, the graphics have been improved. New topics include random number generation, modeling and fitting predator-prey interactions, more emphasis on structural models, testing for linearity, discussion of EM algorithm is more extensive, Bayesian analysis of state space models and MCMC is more extensive (including new scripts in astsa), particle methods are introduced, stochastic volatility coverage is expanded, changepoint detection is introduced (new topic).The

This volume brings together a comprehensive and up-to-date collection of protocols that reflect the diverse experimental strategies. Chapters detail T-cell, macrophage characterization, neutrophil functional assays, organoid culture methods, spatial transcriptomics, RNA FISH, microRNA profiling, and ribosome profiling. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Autoimmunity: Methods and Protocols aims to be a useful and practical guide to new researchers and experts looking to expand their knowledge.

This third edition volume expands on the previous editions with new chapters discussing advancements in mass spectrometry resolution, sensitivity, and speed, including the refinement of the identification of peptides presented on the surface of major histocompatibility proteins. These technologies continue to advance vaccine development, as well as cancer immunotherapy and precision medicine. Furthermore, this new edition introduces new approaches for quantifying immune-active proteins and peptides and explores the increasing role of multi-omics strategies to help researchers further understand immune function. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and comprehensive, Immunoproteomics: Methods and Protocols, Third Editi

This volume discusses protocols for key laboratory techniques used to study Duchenne and Becker muscular dystrophies. The chapters in this book cover a wide array of topics such as biochemical assays, quantification of dystrophin and related proteins, and measurements of muscle physiology. The chapters also cover methods of DMD sequence analysis; processing and isolation of cells from muscle tissue; culture and study of patient-derived cells; and work with animal models of DMD. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Comprehensive and authoritative, Duchenne Muscular Dystrophy: Methods and Protocols is a valuable resource that will contribute to the standardization of practices in the study of dystrophin and dystrophin-related diseas

This volume covers the latest techniques used to study single nucleotide polymorphisms (SNP) genotyping, such as Sanger sequencing, qPCR, Nanopore sequencing, and PACE. The chapters in this book cover topics such as SNP nomenclature, databases, and significance of SNPs in various fields; PCR-based techniques like HRM and CD-PCR; isothermal amplification methodologies; high-throughput methods like FCS-based SNP genotyping; and guidance of data analysis, emphasizing the importance of quality control, statistical analysis, and visualization. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and thorough, Genotyping: Methods and Protocols is a valuable resource for both new and experienced researchers who want to gain a deeper underst

This book is designed to provide students, teachers, and researchers with a text that includes a full range of statistical methods available to address commonly encountered research problems. Many textbooks for introductory, intermediate, and advanced statistics courses focus heavily on parametric methods. However, in practice the assumptions underlying these methods are frequently not met, therefore calling into question their use. This book addresses this issue by presenting parametric, nonparametric, robust, and Bayesian techniques that are appropriate for research scenarios often encountered in practice and typically found in statistics courses. For each of these major topics, the standard parametric approach is presented, along with the assumptions underlying it and the methods used to assess the viability of these assumptions. Next, a set of alternative techniques for the research scenario is presented and applied to the motivating example that begins each chapter. Each chapter c

This volume investigates the methods and techniques used for studying expressivity in language, particularly in language documentation settings. The chapters explore a variety of different expressive

This book discusses some methods of graph decompositions, which are highly instrumental when dealing with a number of fundamental problems of graph theory. The presented topics are united by the role

This book describes in detail a research project dedicated to liquid-particle flow using ultrasound techniques. The project consists of theoretical, experimental, data science, finite element modeling, mechanical design and project management components. The objective of the project was to develop the ultrasonic methodology for measurement and characterization of liquid flow containing solid particles, in online (real-time) measurement conditions. The project consists of primary and complementary studies. The primary studies comprise development of the ultrasonic methodology for the simultaneous measurement of the average particle concentration and flow speed parameters. The developed methodology is based on the ultrasonic attenuation spectroscopy and the sound speed measurement methods, supported by data science programs. The complementary studies include acoustic streaming, designing a small-scale rotational test cell with an annular flow channel, testing it for various applications