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A Best Book of 2021 by Bloomberg BusinessWeek, Time, and The Washington Post The bestselling author of Leonardo da Vinci and Steve Jobs returns with a ';compelling' (The Washington Post) account of how Nobel Prize winner Jennifer Doudna and her colleagues launched a revolution that will allow us to cure diseases, fend off viruses, and have healthier babies.When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled The Double Helix on her bed. She put it aside, thinking it was one of those detective tales she loved. When she read it on a rainy Saturday, she discovered she was right, in a way. As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn't become scientists, she decided she would. Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what

Walter Isaacson's #1 New York Times bestselling history of our third scientific revolution: CRISPR, gene editing, and the quest to understand the code of life itself, is now adapted for young readers!When Jennifer Doudna was a sixth grader in Hilo, Hawaii, she came home from school one afternoon and found a book on her bed. It was The Double Helix, James Watson's account of how he and Francis Crick had discovered the structure of DNA, the spiral-staircase molecule that carries the genetic instruction code for all forms of life. This book guided Jennifer Doudna to focus her studies not on DNA, but on what seemed to take a backseat in biochemistry: figuring out the structure of RNA, a closely related molecule that enables the genetic instructions coded in DNA to express themselves. Doudna became an expert in determining the shapes and structures of these RNA molecules an expertise that led her to develop a revolutionary new technique that could edit human genes. Today gene-editing techno

By bestselling biographer and journalist, a selective collection that illustrates his passage from school to journalist to illustrious biographer.

America's bestselling biographer reveals the origins of the most revolutionary sentence in the Declaration of Independence, the one that defines who we are as Americans--and explains how it should shape our politics today. To celebrate America's 250th anniversary, Walter Isaacson takes readers on a fascinating deep dive into the creation of one of history's most powerful sentences: "We hold these truths to be self-evident, that all men are created equal, that they are endowed by their Creator with certain unalienable Rights, that among these are Life, Liberty, and the pursuit of Happiness." Drafted by Thomas Jefferson and edited by Benjamin Franklin and John Adams, this line lays the foundation for the American Dream and defines the common ground we share as a nation. Isaacson unpacks its genius, word by word, illuminating the then-radical concepts behind it. Readers will gain a fresh appreciation for how it was drafted to inspire unity, equality, and the enduring promise of America. W

NOW A MAJOR SERIES 'GENIUS' ON NATIONAL GEOGRAPHIC, PRODUCED BY RON HOWARD AND STARRING GEOFFREY RUSHEinstein is the great icon of our age: the kindly refugee from oppression whose wild halo of hair, twinkling eyes, engaging humanity and extraordinary brilliance made his face a symbol and his name a synonym for genius. He was a rebel and nonconformist from boyhood days. His character, creativity and imagination were related, and they drove both his life and his science.In this marvellously clear and accessible narrative, Walter Isaacson explains how his mind worked and the mysteries of the universe that he discovered. Einstein's success came from questioning conventional wisdom and marvelling at mysteries that struck others as mundane. This led him to embrace a worldview based on respect for free spirits and free individuals.All of which helped make Einstein into a rebel but with a reverence for the harmony of nature, one with just the right blend of imagination and wisdom to transform