Based on a popular course at Cold Spring Harbor Laboratory, this new manual assembles cutting-edge protocols, helpful hints, and lecture notes to teach researchers from a variety of disciplines the e
The 82nd Cold Spring Harbor Symposium focused on Chromosome Segregation & Structure and addressed theenormous progress in our understanding of the nature and behavior of chromosomes during the life cy
The 82nd Cold Spring Harbor Symposium focused on Chromosome Segregation & Structure and addressed theenormous progress in our understanding of the nature and behavior of chromosomes during the life cy
Most animal cells are polarized, with structurally and functionally distinct regions. This polarization facilitates processes such as differentiation and morphogenesis, directional cell migration, ner
Cilia and flagella are protrusive structures on the surface of cells that perform a variety of functions. The beating of flagella and motile cilia, for example, can be used to propel cells or move mat
Prions are infectious proteins responsible for diseases such as Creutzfeldt-Jakob disease and "mad cow" disease. They are misfolded versions of normal proteins that replicate by converting t
Prevail Through Knowledge: A History of Cold Spring Harbor Laboratory is published to mark the Laboratory's 125th anniversary. Written by historian Jan Witkowski, Executive Director of the Laboratory'
Mitochondria are intracellular organelles that power the cell by metabolizing glucose and other energy sources to generate ATP. They are also critical in programmed cell death, and dysfunction of mito
DNA replication is essential for the propagation of life on Earth. Cells in living organisms must be able to synthesize a complete copy of their DNA with extraordinary precision, so that they can pass
Grounds for Knowledge is an engaging and knowledgeable guide to CSH Laboratory's buildings both historic and new, and to the 150 species of trees that surround them. The superb color photography and d
The 80th Cold Spring Harbor Symposium was held to mark the 150th anniversary of Gregor Mendel's landmark 1865 presentation of his paper "Experiments on Plant Hybridization", which laid the groundwork
The Yeast Genetics & Genomics course is a modern, state of the art, laboratory course designed to teach the full repertoire of genetic approaches needed to dissect complex problems in the yeas
"Fungal infections affect millions of individuals worldwide. They a particular danger to immunocompromised individuals, such as those with HIV/AIDS, and invasive infections often have a mortality rate
"The skin is a continually renewing organ that acts as a protective barrier isolating us from the external environment. This book examines the cells that make up the skin and their functions, as well
Nineteen chapters review the process and regulation of protein synthesis as understood through recent research. Among the topics are new insights and challenges in the mechanism of eukaryotic translat
Life arose on Earth more than three billion years ago. How the first self-replicating systems emerged from prebiotic chemistry and evolved into primitive cell-like entities is an area of intense rese
Electronic devices can now be used to analyse and modulate the electrical activity within the nervous system. This book explores how development of these devices is leading to new diagnostics and trea
Correct folding of proteins is critical for cell function, and accumulation of misfolded proteins is a feature of a number of neurodegenerative conditions. This book examines the mechanisms that ensur
Complex molecular machinery within the cells of the inner ear allow it to sense sounds of different frequencies and relay information to the brain. This volume examines the nature of this machinery, t
Next-generation sequencing technology allows rapid sequencing of a patient's DNA. This book introduces the technology and describes how it may be used in personalized medicine to diagnose diseases su
RNA (ribonucleic acid) molecules drive much of cellular action. Messenger RNA (mRNA) relays genetic information from DNA to ribosomes to direct the formation of proteins. At the same time, noncoding R
Lab Dynamics is a unique guide to the interpersonal side of scientific research and management. The book provides practical solutions to some of the toughest problems that working scientists and scien
Viruses that are transmitted via the fecal-oral route and may cause liver damage are known as enteric hepatitis viruses. These viruses, which include the hepatitis A and E viruses (HAV and HEV, respec
