Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

(Book Jacket Status: Jacketed)The urbane authority that Vladimir Nabokov brought to every word he ever wrote, and the ironic amusement he cultivated in response to being uprooted and politically exile

(Book Jacket Status: Jacketed)R. K. Narayan (1906—2001) witnessed nearly a century of change in his native India and captured it in fiction of uncommon warmth and vibrancy. The four novels collected h

(Book Jacket Status: Jacketed)In the novels of R. K. Narayan (1906-2001), the forefather of modern Indian fiction, human-scale hopes and epiphanies express the promise of a nation as it awakens to its

Ralph Waldo Emerson is one of the best-loved figures in nineteenth-century American literature. Though he earned his central place in our culture as an essayist and philosopher, since his death his r

This collection presents the Brownings' work in the context of their lives: the early years and their initial friendship, their courtship and marriage, the fifteen happy years they spent living in It

Naguib Mahfouz's trilogy of colonial Egypt is the story of a Muslim family in Cairo during Britain's occupation of Egypt in the early decades of the twentieth century.The novels of The Cairo Trilogy

(Book Jacket Status: Jacketed)In the early eleventh century Murasaki Shikibu, a lady in the Heian court of Japan, wrote what many consider to be the world’s first novel, more than three centuries befo

A beautifully jacketed hardcover edition of the Nobel Prize-winning author’s beloved epic novel about a stubbornly independent Icelandic sheep farmer and his spirited daughter.Set in the early twentie

(Book Jacket Status: Jacketed)?The Age of Innocence, one of Edith Wharton’s most renowned novels and the first by a woman to win the Pulitzer Prize, exquisitely details the struggle between love and r

This anthology brings together hundreds of haiku by the Japanese masters - Basho, Issa, Buson, Shiki - with superb examples from nineteenth- and twentieth-century writers. The pioneering translator R

The novel Offshore limns the marginal existence of an eccentric assortment of barge dwellers on the Thames in the early 1960s, a group of misfits who are drawn to life on the muddy river in exile fro

(Book Jacket Status: Jacketed)Shakespeare forged his tremendous art in the crucible of his comic imagination, which throughout his life enveloped and contained his tragic one. His early comedies—with

(Book Jacket Status: Not Jacketed)Set in the magical Wessex landscape so familiar from Thomas Hardy’s early work, Tess of the D’Urbervilles is unique among his great novels for the intense feeling tha

(Book Jacket Status: Jacketed)The Portrait of a Lady is the most stunning achievement of Henry James's early period--in the 1860s and '70s when he was transforming himself from a talented young Americ

(Book Jacket Status: Jacketed)The brevity of Muriel Spark’s novels is equaled only by their brilliance. These four novels, each a miniature masterpiece, illustrate her development over four decades. D

(Book Jacket Status: Not Jacketed)Rousseau's ideas have influenced almost every major political development of the last two hundred years, and are crucial to an understanding of phenomena as diverse a

Poets from around the world celebrate the universal appeal of the comforts of home in this unique anthology. Whether inhabited or remembered, whether solitary or teeming with family, whether a refuge from the world or a connection to a community, home is essential to the self. The pages of this anthology feature homecomings and leavetakings, urban apartments and cozy cottages, stately mansions and hermits' huts. In these poems we can watch a medieval housewife explain to her uncomprehending husband how she has spent her day; we can join with Robert Herrick as he gives thanks for his "humble roof . . . weatherproof"; we can peep in on Amy Lowell in the bath and John Donne in his bed, and join Joy Harjo for a meal at the kitchen table. Home can mean many things: from Horace's rural farm to Billy Collins's favorite armchair, from Milton's "blissful bower" in Paradise to Imtiaz Dharker's "Living Space" in the slums of Mumbai. Mary Oliver imagines her dream house, Emily Dickinson dwells in

Peter Carey's two Booker Prize-winning novels, in one handsome hardcover volume. EVERYMAN'S LIBRARY CONTEMPORARY CLASSICS.Oscar and Lucinda is a sweeping, irrepressibly inventive novel set in nineteen

Here in one volume is James Ellroy's first great body of work, an epic re-envisioning of postwar Los Angeles--etched in red and black and film-noir grays.The Black Dahlia depicts the secret infrastruc

The story of an irrepressible orphan girl in the Swiss Alps, written in 1881, has long been one of the most beloved and best-selling children's classics in the world. Heidi's story begins when sh

A newly edited selection from the most famous, colorful, and vivid diarist in the English language--in the most accessible, uncensored, and clearly annotated edition available.Though he rose to become

On the hundredth anniversary of the end of World War I: a hardcover edition of the classic tale of a young German soldier's harrowing experiences in the trenches, widely acclaimed as the greatest war novel of all time.When twenty-year-old Paul Bäumer and his classmates enlist in the German army during World War I, they are full of youthful enthusiam. But the world of duty, culture, and progress they had been taught to believe in shatters under the first brutal bombardment in the trenches. Through the ensuing years of horror, Paul holds fast to a single vow: to fight against the principle of hate that meaninglessly pits young men of the same generation but different uniforms against one another. Erich Maria Remarque's classic novel not only portrays in vivid detail the combatants' physical and mental trauma, but dramatizes as well the tragic detachment from civilian life felt by many upon returning home. Remarque's stated intention--"to tell of a generation of men who, even though they

Poems of Gratitude is a unique anthology of poetry from around the world and through the ages celebrating thanksgiving in its many secular and spiritual forms. For centuries, poets in all cultures hav

W. Somerset Maugham’s masterwork is the coming-of-age story of Philip Carey, a sensitive young man consumed by an unrequited and self-destructive love.Born with a clubfoot, Philip is orphaned as a child and raised by unsympathetic relatives. Sent to a boarding school where he has difficulty fitting in, he grows up with an intense longing for love, art, and experience. After failing to become an artist in Paris, he begins medical studies in London, where he meets Mildred, a cold-hearted waitress with whom he falls into a powerful, tortured, life-altering love affair. This is the most autobiographical of Maugham’s works, with Philip’s malformed foot standing in for Maugham’s stutter, and the character’s painful romantic struggles inspired by the author’s own intense love affairs with both men and women. A brilliant and deeply moving portrayal of the price of passion and the universal desire for connection,Of Human Bondage stands as one of the most accomplished novels in English literatur

Edward Gibbon’s classic timeless work of ancient Roman history in 6 volumes collected into 2 boxed sets, in beautiful, enduring hardcover editions with elegant cloth sewn bindings, gold stamped covers

A furor erupts when the Sultan hires a group of artists, under the direction of Master Uncle, to illuminate a great book in the European style to celebrate his reign at a time in which all figurative

In Everyman’s Library for the first time—one of the most moving and eloquent accounts of the Holocaust, read by tens of millions of people around the world since its publication in 1947.The Diary of a

In 1956, Updike published a story, "Snowing in Greenwich Village," about a young couple, Joan and Richard Maple, at the beginning of their marriage. Over the next two decades, he returned to these ch

(Book Jacket Status: Jacketed)Written on the front lines in Vietnam, Dispatches became an immediate classic of war reportage when it was published in 1977.From its terrifying opening pages to its fina

This sweeping literary tour of Scotland from the Middle Ages to the present gathers the best of Scottish poetry in one volume, from beloved classics to contemporary voices.The poetic tradition in Sco

(Book Jacket Status: Jacketed)Flann O’Brien, along with Joyce and Beckett, is part of the holy trinity of modern Irish literature. His five novels–collected here in one volume–are a monument to his in

(Book Jacket Status: Jacketed)For the first time, all the major works of this beloved writer are gathered together in one hardcover volume. Poet, artist, and mystic, Kahlil Gibran was born in 1

(Book Jacket Status: Jacketed)With a New Introduction by Hilary SpurlingThe Raj Quartet, Paul Scott's epic study of British India in its final years, has no equal. Tolstoyan in scope and ?Proustian in

(Book Jacket Status: Jacketed)With a New Introduction by Hilary Spurling The Raj Quartet, Paul Scott's epic study of British India in its final years, has no equal. Tolstoyan in scope and ?Proustian i

The two original short novels brought together here - in new translations by award-winning translators - were both literary gambles of a sort for Dostoevsky.The Double, written in Dostoevsky's youth, was a sharp turn away from the realism of his first novel, Poor Folk. The first real expression of his genius, The Double is a surprisingly modern hallucinatory nightmare in which a minor official named Goliadkin becomes aware of a mysterious doppelganger - a man who has his name and his face and who gradually and relentlessly begins to displace him with his friends and colleagues. In the dilemma of this increasingly paranoid hero, Dostoevsky makes vividly concrete the inner disintegration of consciousness that would become a major theme of his work.The Gambler was written twenty years later, under the pressure of crushing debt. It is a stunning psychological portrait of a young man's exhilarating and destructive addiction, a compulsion that Dostoevsky - who once gambled away his young wif

(Book Jacket Status: Jacketed)With this dizzyingly rich novel of ideas, Thomas Mann rose to the front ranks of the great modern novelists, winning the Nobel Prize in Literature in 1929. The Magic Moun

Here - for the first time in one volume - are two original works on the experience of Chinese immigrants in America. In both books Maxine Hong Kingston mines her family's past and her culture's stori

The Plague - written in 1947 and still relevant - is a tale of horror, survival, and resilience in the face of a devastating epidemic. The Fall (1956), which takes the form of an astonishing confessio

Anton Chekhov, widely hailed as the supreme master of the short story, also wrote five works long enough to be called short novels, here brought together in one volume for the first time, in a new tr

Alfred, Lord Tennyson was a more complex writer than his status as Queen Victoria’s favorite poet might suggest. Though capable of rendering rapture and delight in the most exquisite verse, in another