Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Let’s read comics! I Can ReadComicsis an early reader line that familiarizes children with the world of graphic novel storytelling and encourages visual literacy in emerging readers.Hide & Seek with Clyde & Monique: Clyde in Plain Sightis the newest offering from comics powerhouse Graham Annable.Monique is excited to play with her best friend, Clyde! Clyde claims to be the best hider, but Monique is determined to prove him wrong in this fun seek-along game of hide and seek.Hide & Seek with Clyde and Monique: Clyde in Plain Sightis a Level Two I Can ReadComic, geared toward kids who are comfortable with comics, can read on their own, but still need a little help.

Fish and Worm is the latest offering from I Can Read! Comics, an early reader line that familiarizes children with the world of graphic novel storytelling and encourages visual literacy in emerging readers.Fish returns for another adventure with a wiggly new friend in Fish and Worm by the inimitable Sergio Ruzzier. Fish and Worm is a Level One I Can Read! Comic, perfect for shared reading with young readers new to graphic novel storytelling.

Crab must save Snail from Evil Eel's curse in their third unforgettable seaside adventure in the graphic early reader series by New York Times bestselling author Beth Ferry and illustrator Jared Chapman.The Evil Eel is so evil that making narwhals cry is one of her favorite hobbies. So evil in fact that just one sting turns friendly, sweet Snail into...Snevil!!!! Complete with a black cape, Snevil sets out to destroy everything in her path, including Crab. In order to save himself--and his best friend--Crab must become a hero. Will he be able to stop evil from destroying the splash zone before it's too late?Crab and Snail are everyone's new favorite characters in the graphic early reader space. Fans of Narwhal & Jelly and Beak & Ally will love these quirky characters and clever stories.A character-based volume that reads like a cross between SpongeBob SquarePants and The Muppet Show.--Publishers Weekly (starred review) for The Invisible Whale (Book One)

Crab and Snail set out on a mission to be cooler than cool in their second unforgettable seaside adventure in the graphic early reader series by New York Times bestselling author Beth Ferry and beloved illustrator Jared Chapman.Starfish is pointy-perfect, so wow to the wow! And her tidal pool is filled with friends and fun things. But Crab and Snail weren't invited. While the best beach friends do everything they can to catch Starfish's attention and score an invite, they begin to realize that being kind just might be the coolest of cool.Crab and Snail are everyone's new favorite characters in the graphic early reader space. Fans of Narwhal & Jelly and Beak & Ally will love these quirky characters and clever stories.A character-based volume that reads like a cross between SpongeBob SquarePants and The Muppet Show.--Publishers Weekly (starred review) for The Invisible Whale (Book One)

A local college professor comes to Ella Mentry School to help students learn basic history and improve their scores on a standardized test, using some very unusual techniques.

Let's read comics! I Can Read Comics is an early reader line that familiarizes children with the world of graphic novel storytelling and encourages visual literacy in emerging readers.Fish loves his pebble collection, but he wishes for more so he goes on a journey to find some. What he doesn't expect is to make a new friend along the way!Fish and Clam is a Level One I Can Read Comic, perfect for shared reading with young readers new to graphic novel storytelling.Praise for Fish and FriendsA Geisel HonorPublishers Weekly Best Book of the YearKirkus Reviews Best Book of the YearJunior Library Guild Selections5 starred reviews (from Publishers Weekly, Kirkus Reviews, School Library Journal, and The Horn Book)

New York Times bestseller! From Matt and Rebecca Zamolo, creators of the mega-popular YouTube series Game Master Network, comes a new thrilling novel about everyone’s favorite mystery-solving team as they go toe-to-toe with the mysterious and menacing Game Master.Rebecca Zamolo is on a mission to save her summer. Instead of going to camp like she’d planned, she’s been stuck in summer school. But today is the day! She’s going to present her final science assignment—using her Nana’s borrowed vintage zoetrope—and then she’ll be free to have fun.But as Becca and her classmates wait for her teacher to arrive, a menacing voice comes over the intercom claiming to be the Game Master! The kids quickly discover that the Game Master has locked the doors, scared off the teachers, and made it clear that if Becca and her friends don’t solve the clues that have been left behind, they’ll never get back Becca’s irreplaceable zoetrope, never finish summer school, and never get to enjoy wh

The Secret Life of Pets meets The Bad Guys in DOWN IN THE DUMPS, an all-new, highly illustrated, early chapter book series about three unlikely friends--a rotten banana, a broken tea pot, and a crusty blob of gum--and their adventures together in the local town landfill. To Nana, there isn't a better, more beautiful home for a mushy, moldy banana than the Westerfield Waste Transfer & Recycling Center! Nana loves living at the dump! She welcomes every new piece of trash with a hardy hug and happy hello.And in The Mystery Box, the first adventure in the Down in the Dumps series, when a Teddy Tedd Ted doll still perfectly wrapped in his gift box arrives, Nana realizes that not everyone is ready to be thrown away. Will Nana and her friends be able to navigate the many dangers of the dump to help Teddy Tedd Ted find his way home?The Mystery Box is the first book in the Down in the Dumps series from beloved author-illustrator Wes Hargis. It will have even the most reluctant readers takin

TOY STORY meets the GARBAGE PAIL KIDS in A VERY TRASHY CHRISTMAS, the third of four books in the hilarious, new, highly illustrated early chapter book series DOWN IN THE DUMPS, about three unlikely friends―a rotten banana, a broken tea pot, and a crusty blob of gunk―and their adventures together in the local town landfill. Santa who? Nana has never heard about Christmas until the old toys of the Westerfield Waste Transfer and Recycling Center tell her about the most magical night of the year! And when Nana learns that Santa Claus delivers toys to all the good boys and girls, she insists on writing him her own letter. But when Santa arrives with their gifts in tow, the Forklift of Doom mistakes his sleigh for rubbish. Can Nana and her trash friends band together to save Christmas before it’s too late?A VERY TRASHY CHRISTMAS is the third book in the hilarious new chapter book series DOWN IN THE DUMPS from beloved author-illustrator Wes Hargis. It’ll have even the most reluctant readers w

TOY STORY meets the GARBAGE PAIL KIDS in TRASH VS. TRUCKS, the second book of four books in the hilarious, new, highly illustrated early chapter book series DOWN IN THE DUMPS, about three unlikely friends―a rotten banana, a broken tea pot, and a crusty blob of gunk―and their adventures together in the local town landfill. Oh no! The trucks are planning to move Nana’s beautiful home at the Westerfield Waste Transfer and Recycling Center. And to a trash barge of all places, too! Nana isn’t about to give up her beloved dump without a fight, but she’ll need a plan first. Will Nana and her trash friends be able to save their home and stop the trucks from taking apart everything they’ve worked so hard to build?TRASH VS. TRUCKS is the second book in the hilarious, highly illustrated new chapter book series DOWN IN THE DUMPS from beloved author-illustrator Wes Hargis. It’ll have even the most reluctant readers clamoring for more adventures!

When beloved character Little Critter® hears something going “tap-tap” in the night, he is determined to find the source, in this Level One I Can Read Comic.It’s bedtime for Little Critter and Little Sister, but when there’s a strange sound in the night, the two set out to find the source of the "tap-tap." Things that look like monsters in the dark turn out to be innocent in this nighttime adventure! Will they ever find out what’s making the sound?Emergent readers will enjoy the humor and mystery in Little Critter: Night Night! Sleep Tight!, a Level One Little Critter I Can Read Comics story.

Young readers will be swept up in Pinkalicious's pinkatastic Parisian adventure in this Level One I Can Read!Pinkalicious gets distracted and loses track of Mommy, Daddy, and Peter on a family trip to Paris. But fortunately, Pinkalicious remembers Mommy's advice and knows what to do!Pinkalicious: Lost in Paris is a Level One I Can Read, which means it's perfect for children learning to sound out words and sentences. Whether shared at home or in a classroom, the short sentences, familiar words, and simple concepts of Level One books support success for children eager to start reading on their own.Readers can watch Pinkalicious and Peter on the funtastic PBS Kids TV series Pinkalicious & Peterrific!

Cat's out of the bag! In this fourth hijinks-filled adventure, Squash and Ginny are preparing for another mission when Magnus suddenly arrives in search of the Staff of Knowledge. Much to everyone's surprise, it's not in the Spirit World--it's in the Human World!With Fern and Lotus's help, Squash and Ginny locate the staff right away. But before they can return it to Magnus, Squash tries to conjure snacks (obviously), accidentally triggering a massive power surge that causes the orbs to disperse throughout the Human World. The orbs are now lost, and the squad must retrieve them before mysterious forces get to them first!Praise for Susie Yi"Look no further for PAWSSIBLY the sweetest book on the shelf!"--Ben Clanton, bestselling author of the Narwhal and Jelly series"Lovers of cuteness will delight in this adorable kitty adventure."--Jim Benton, author of the Catwad series"A story to treasure, full of kindness in a magical world."--Kirkus Reviews

The Cool Bean faces the super slide in this Level Two I Can Read by the #1 New York Times bestselling duo Jory John and Pete Oswald!It's a perfect day at the community pool for a swim. The cool beans are the best swimmers in town. Check out how they dive! Look at how they cannonball! Watch how they backflip! YOW!As for the Cool Bean, the shallow side of the pool is the only side of the pool he treads water on. Until one day, the Cool Bean sees the super slide and finds the courage to finally ride the slide...or does he? Find out in this splashy story about taking chances, trying new things, and leaning on your friends.The Cool Bean Makes a Splash is a Level Two I Can Read book, geared for kids who read on their own but still need a little help. Whether shared at home or in a classroom, the engaging stories, longer sentences, and language play of Level Two books are proven to help kids take their next steps toward reading success.

When noisy neighbors move in for the winter, will Beak & Ally ever find peace and quiet? Find out in Beak & Ally: Snow Birds, the latest in this Theodor Seuss Geisel Honor Award-winning series from cartoonist Norm Feuti!Winter is coming! Beak loves the snow, but his hopes are dashed when Ally informs him the swamp stays warm year-round and not much changes. As a matter of fact, the only big change is that it gets a lot more crowded! Beak soon discovers what Ally means when the snow birds arrive . . . Hawaiian shirt-wearing, music-jamming new neighbors who have flown south for the winter.At first, Beak is thrilled when they decide to spend their vacation in his tree--he loves to party! But when the noise gets louder and louder, it's time for Beak and Ally to take action. Confronting new friends can be hard, but anything is possible when you have your best friend by your side to help.

Now in paperback, this Newbery Honor– and Walter Award–winning novel in verse is a heartbreakingly hopeful story about an Indian American girl whose life is turned upside down when her mother is diagnosed with leukemia.Reha feels torn between two worlds: school, where she’s the only Indian American student, and home, with her family and their close-knit community. But Reha’s parents don’t understand why she’s conflicted—they only notice when Reha doesn’t meet their strict expectations. Reha feels especially disconnected from her mother, or Amma.Then Reha finds out that Amma is sick. Really sick.Reha, who dreams of becoming a doctor even though she can’t stomach the sight of blood, is determined to make her Amma well again. She’ll be the perfect daughter, even if it means giving up her attempts to fit in at school, if it means saving her Amma’s life.From acclaimed author Rajani LaRocca comes a radiant novel in verse—which the author describes as “the book of her heart”—about the ties th

Who's cooking in the school kitchen? Join the super-sleuthing Cryptid Club in The Chupacabra Hoopla, the third book in the hilarious graphic novel chapter book series from Emmy Award-winning writer Michael Brumm and bestselling illustrator Jeff Mack.The Cryptid Club is hungry for a new adventure! When the school lunches go missing and mysterious spaghetti-sauce tracks lead to the woods, Lily has no choice but to enlist the help of her main nemesis, Daisy, to help catch the crook.But as the school continues to go without any food, the starving students begin fighting over the last crumbs. Then, the school custodian reports that his sandwich was stolen by a large-eyed creature with sharp claws! Can Lily, Henry, Oliver, Ernie, and Daisy solve the mystery of the Chupacabra before the entire school turns into the hunger games?Everything is not as it seems in this laugh-out-loud graphic novel series debut by Emmy Award-winning writer for The Late Show with Stephen Colbert Michael Brumm and b

A big storm is brewing . . . but these pals have each other’s backs—rainorshine—in the third book of Beak & Ally, a seriesperfect for fans of Narwhal & Jelly, emerging readers, and all kids who love comics.Ally’s enjoying a peaceful, rainy day down in the swamp until Beak tells her that a big storm is coming. As Ally makes her way home to prepare, she can’t help but notice other swamp critters struggling to get ready for the bad weather. Even though she has a lot to do, she offers them a hand.But before she knows it, the storm is upon her, and shehas totake shelter in the first secluded spot she can find. Once the storm passes, Ally returns to find her once beautiful home in utter ruin!Will Ally be able to save her home, or will she be forced to leave the swamp . . . for good?

The thrilling third installment in the latest arc of BRAVELANDS! Set in the African highlands and told from three different animals’ points of view, dedicated fans and readers new to the Bravelands world will love this exciting new adventure. Bravelands is in turmoil. With Thorn dead, the animals of the plains desperately search for the next Great Parent, a role Prance is afraid to fill. Chase hides in plain sight amidst Grandmother’s most loyal creatures, praying that the terrible antidote she’s discovered will continue to hold the snake’s power over her at bay. And Bramble finds himself up against a foe he couldn’t have imagined: his own poisoned troop. Can these three unlikely allies stop the great serpent before her venom corrupts them all?

One kingdom. Three worlds. Explore the secrets of the Bamboo Kingdom in the second installment of this thrilling new series from bestselling Warriors author Erin Hunter, perfect for fans of Wings of Fire and Endling.For three pandas in the Bamboo Kingdom, secrets have changed everything. Rain, Ghost, and Leaf have only just discovered the truth about their families--but they don't have all the facts. And while they attempt to piece together the puzzle of their pasts, a threat is growing ever stronger in their homeland--a liar masquerading as a leader.Sunset, the so-called Dragon Speaker, has his own agenda, and the discovery of the triplets from an ancient prophecy will only get in his way. While Rain and Leaf struggle to agree on the next right moves, Ghost, struggling to adapt to panda life, falls under Sunset's spell.Separated, the three panda siblings are left without the information they need to take the traitorous Dragon Speaker down. But if they can find each other--and trust ea

One kingdom. Three worlds. It’s WARRIORS—but with pandas! This thrilling new series from bestselling author Erin Hunter follows three panda cubs, separated at birth, who must join together to complete a prophecy and save their home.The pandas of the Bamboo Kingdom have never forgotten the great flood that ended the peaceful life they’d always known. But for three young creatures born that day, the flood marks not an end, but a beginning—the beginning of their struggles to find a place in very different worlds.Leaf, raised in the sparse Northern Forest, works tirelessly to help her family find bamboo to eat; Rain, hot-tempered, refuses to accept a suspicious new leader in her Southern Forest community; and Ghost, clumsy and uncoordinated, worries he’ll never fit in with his hunter family in the mountains.None of them know that the others are out there, but thanks to a mysterious tiger that’s been threatening the Kingdom, they will soon find each other—and fulfill a prophecy that had bee

Join the spunky and powerful Sparkle Dragons as they blast their glitter fire and put their brains together to save the queendom from polka-dotted pollution in this hilarious, easy-to-read graphic novel.Meet the Sparkle Dragons: the spunkiest crew in all of Princess Puff's queendom! Trixie is fierce with brains and beauty. Rue is tough as nails with a heart of shimmering gold. And, last but not least, Glinda, who often has her head in the clouds, but her out-of-the-box problem-solving can be her strongest asset. With their unique powers combined, they are an unstoppable force! And let's be honest: fighting off bad guys with glitter beams can be pretty hilarious . . . and sticky! Bad guys can be quite clever in this queendom, but the Sparkle Dragons don’t miss a trick. When the Rain River is polluted with polka dots, Robert—not Bob—the Troll takes the heat for it. But he says he is innocent! Not to worry—the Sparkle Dragons are hot on the tails of the true culprits. That is, if Princess

The thrilling conclusion to the epic middle grade fantasy trilogy from Katherine Applegate, the New York Times bestselling and Newbery Award-winning author of The One and Only Ivan (now a major motion picture!), The One and Only Bob, Wishtree, and Crenshaw!In the beginning, Byx's original quest was to discover if there were more of her kind, or if she was destined to become an endling--the last dairne alive. She did indeed find more dairnes, and along the way she also created allies among other creatures in her world, including humans, felivets, raptidons, and wobbyks.But Byx and her new friends soon learned that it wasn't just dairnes in jeopardy of extinction, but that everyone was at risk. With the world in unprecedented danger, Byx must rally creatures of all kinds to lead a revolution.Katherine Applegate's Endling series has so far earned a collective five starred reviews, and each of the prior books has debuted on the New York Times bestseller list. She once again delivers an act

With more than 29 million books sold, the My Weird School series really gets kids reading In this eighth book in the My Weirder-est School series, A.J. and his friends join the Maker movement Who's re

Now in paperback, the fourth installment in the perennially beloved and bestselling Wayside School series by Newbery Medal-winning author Louis Sachar stars all your favorite students and teachers, wi

With more than 27 million books sold, the My Weird School series really gets kids reading In this seventh book in the My Weirder-est School series, A.J. and his friends learn some very weird ways to p

The fifth arc in the sensational My Weird School series, which in its first four arcs has sold more than 23 million copies worldwide! In this sixth installment, A.J. and the gang begin music lessons!A

With more than 23 million books sold, the My Weird School series really gets kids reading!In this second book in the My Weirder-est School series, A.J. and his friends are getting a substitute.Miss Po

The fourth arc in the sensational My Weird School series, which has sold more than 12 million copies worldwide! In this twelfth and final installment, A.J. and the gang are protesting the new lunch la

The fourth arc in the sensational My Weird School series, which has sold more than 12 million copies worldwide! In this eleventh installment, A.J. and the gang are craving sweet treats but the substit

With more than 12 million books sold, the My Weird School series really gets kids reading! In this tenth book in the new My Weirdest School series, Sprinkles Newman, the local TV meteorologist, is com

With more than 11 million books sold, the My Weird School series really gets kids reading! In this ninth book in the new My Weirdest School series, Miss Universe is coming to Ella Mentry School!

Think fast with A.J. and Andrea from My Weird School!Did you know that the word “independence” never appears in the Declaration of Independence? Did you know that soldiers in World War I collected tho

With more than 11 million books sold, the My Weird School series really gets kids reading!In this eighth book in the new My Weirdest School series, it’s Grandparents Day at Ella Mentry School! Alexia’

She’s your best friend. She knows all your secrets. That’s why she’s so dangerous. A single mother’s life is turned upside down when her best friend vanishes, in this chilling debut thriller in the ve

With more than 10 million books sold, the My Weird School series really gets kids reading!In this seventh book in the new My Weirdest School series, it’s picture day at Ella Mentry School! This year,

With more than 10 million books sold, the My Weird School series really gets kids reading!?In this sixth book in the new My Weirdest School series, the teachers of Ella Mentry School are on strike! A.

Greg Iles continues the electrifying story begun in his smash New York Times bestsellerNatchez Burning in this highly anticipated second installment of an epic trilogy of blood and race, family and ju

With more than 9 million books sold, My Weird School really gets kids reading!In this fourth book in the new My Weirdest School series, the students of Ella Mentry School are learning about fire safet

Greg Iles continues the electrifying story begun in his smash New York Times bestseller Natchez Burning in this highly anticipated second installment of an epic trilogy of blood and race, family and j