Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Features a range of previously unpublished works as well as pieces written in response to World War I, in a comprehensive survey that that sheds light on how Wharton used poetry to express the deeply

In one volume, four novels by "the real Fitzgerald": scintillating, sexually frank tales of the desperate pursuit of pleasure and status in Jazz Age AmericaThe early novels of John O'Hara, like those

The poetry of early America is seen afresh in this groundbreaking new volume in The Library of America's acclaimed American Poetry anthology series, charting its flowering over a span of almost two c

This volume brings together The Sacred Fount (1901), one of Henry James's most unusual experiments, and The Wings of the Dove (1902), one of his most beloved masterpieces and the novel that inaugurat

Draws on the collections of the nineteenth-century Jewish-American poet from her early works, published in her teens, to her definitive writings in Songs of a Semite, in a volume that offers insight i

From the earliest years of the American republic, Paris has provoked an extraordinary American literary response. An almost inevitable destination for writers and thinkers, Paris has been many things

Stories and Early Novels includes every story that Chandler did not later incorporate into a novel - thirteen in all. Drawn from the pages of Black Mask and Dime Detective, these stories show how Cha

A volume of key works by the early twentieth-century midwestern American poet offers insight into his ability to capture the voices of the nation's workers and disadvantaged groups, in an anthology th

Explores the twentieth-century poet's emulation of the everyday protagonist's search for connection, discussing the accomplishments of such early works as Homage to Mistress Bradstreet, his evocative

A revealing look inside the mind of one of the great writers of detective fiction includes essays, 24 stories, and an early version The Thin Man.

Includes the work of nearly ninety writers, including Ernie Pyle, Martha Gellhorn, A.J. Liebling, and Edward R. Murrow, capturing the urgency of events as they happened.

A collection of Muir's most significant and best-loved works, including an account of his early years, descriptions of his experiences in the Sierra region, an adventure story about an Alaskan dog, an

A novelistic view of America, from the robber barons to the labor radicals to the great American artists of the early twentieth century is captured by an author who lived through it in a trio of novel

Includes the work of nearly ninety writers, including Ernie Pyle, Martha Gellhorn, A.J. Liebling, and Edward R. Murrow, capturing the urgency of events as they happened

Includes the work of nearly ninety writers, including Ernie Pyle, Martha Gellhorn, A.J. Liebling, and Edward R. Murrow, capturing the urgency of events as they happened

The great American realist's early novels developed key themes that preoccupied Howells throughout his career

The first collected edition of an essential, Pulitzer Prize-winning Beat poet, the indispensable voice whose deep ecological vision and Buddhist spirituality grows more relevant with each passing decade Gary Snyder is one of America’s indispensable poets, the “Thoreau of the Beat Generation” and our “laureate of Deep Ecology.” Now, for the first time, all of Snyder’s poetry is gathered in a single, authoritative Library of America volume. Here are all of Snyder’s published books of poetry spanning a career of almost seventy years. Early collections such as Riprap and Cold Mountain Poems, Myths & Texts, and The Back Country reflect his hardscrabble rural upbringing in the Pacific Northwest; his life as a logger, fire-lookout, freighter crewman, carpenter, and trail-blazer; his lifelong interest in Native American oral literatures; and his pioneering studies of Zen Buddhism. In Turtle Island and Axe Handles––the former a winner of the Pulitzer Priz

For the 400th anniversary of Moliere's birth, all of Richard Wilbur's unsurpassed translations of Moli re's plays--themselves towering achievements in English verse--are brought together for the first time in this two-volume gift set. One of the most accomplished American poets of his generation, Richard Wilbur (1921-2017) was also a prolific translator of French and Russian literature. His verse translations of Moli re's plays are especially admired by readers and are still performed today around the world. Wilbur, the critic John Simon wrote, makes Moli re into as great an English verse playwright as he was a French one. Now, for the first time, all ten of Wilbur's unsurpassed translations of Moli re's plays are brought together in two-volume boxed set, fulfilling the poet's vision for the translations. The first volume comprises Moli re's delightful early farces The Bungler, Lover's Quarrels, and The Imaginary Cuckhold, or Sganarelle; the comedies The School for Husbands and The Sch

Library of America launches its definitive multi-volume edition of John Updike's novels with the four early works that signaled the arrival of one of the most gifted young novelists of the 1960sJohn U

The definitive Philip Roth edition continues with three novels written in his late sixties and early seventies. The Dying Animal (2001) marks the final return of David Kepesh from The Breast (1972) and The Professor of Desire (1977). Now an eminent cultural critic in his sixties, Kepesh expertly seduces a beautiful twenty-four-year-old daughter of Cuban exiles only to find himself torn by sexual jealousy and the anguish of loss. As The Plot Against America (2004) begins, aviation hero Charles A. Lindbergh has defeated Franklin Roosevelt in the 1940 presidential election, and fear invades every Jewish household in America. Lindbergh has publicly blamed the Jews for pushing America toward a pointless war with Nazi Germany, and now in office, he negotiates a cordial “understanding” with Adolf Hitler. What follows for Jews during the Lindbergh presidency—most particularly in the Newark household of the boy Philip Roth—is the subject of an extraordinary work of historical imagination. With

This volume brings together 22 tales, the very best of Howard Phillips Lovecraft's fiction. Early stories such as "The Outsider," "The Music of Erich Zann," "Herbert West - Reanimator," and "The Lurk

Harold Bloom, author of The Western Canon and one of the world's most renowned literary critics, surveys Walt Whitman's vast poetic work, from early notebook fragments of Song of Myself to the late p

A two-volume selection of the American playwright Williams (1911-83) most influential work. The first volume opens with the rediscovered early plays, and includes The Glass Menagerie , Streetcar ,

A comprehensive anthology collects fifty-eight superb sermons from diverse periods of American history, showing the development of this neglected literary form from Colonial times to the television ev

Three dark novels--Wieland, Arthur Mervyn, and Edgar Huntly--from 1798 and 1799 by America's first professional novelist demonstrate his influence on the development of the Gothic school of Nathaniel

The only complete anthology of the twentieth-century American modernist's poetry includes more than fifty poems not previously collected, early versions of famous poems, and the most comprehensive sel

Presents six early classics of American noir fiction: James M. Cain's The Postman Always Rings Twice , Edward Anderson's Thieves Like Us , Kenneth Fearing's The Big Clock , William Lindsay Gresham'

Ursula Le Guin's beloved YA series gathered for the first time in a deluxe collector's edition for every readerThis fifth volume in the definitive Library of America edition of Ursula K. Le Guin's wor

A delightful keepsake edition of the incomparable wisdom of America's greatest poet, distilled from his fascinating late-in-life conversations with Horace Traubel.What is essential in life? How do we

The indispensable writings of our modern-day Thoreau, more relevant now than ever, in a special two-volume edition prepared in consultation with the author.Writing with elegance and clarity, Wendell B

Ursula K. Le Guin's most ambitious novel, a richly-imagined vision of post-apocalyptic California, in a newly expanded version prepared shortly before her deathThis fourth volume in the authoritative

For the first time in a deluxe boxed set, the definitive edition of Richard Wright's landmark works in the form in which he intended them to be read.Here, in authoritative new texts based on the autho

In one volume, two landmark novels about the terrible power of race in America from one of the foremost African American writers of the past century.Ann Petry is increasingly recognized as one of the

A Wrinkle in Time was only the beginning: rediscover an American classic with all seven of its sequels in this deluxe, two-volume collector's edition boxed set.Here, for the first time, in a newly-pre

A Wrinkle in Time was only the beginning: rediscover an American classic and its three sequels in this deluxe Library of America editionThis Library of America volume presents Madeleine L'Engle's icon

A Wrinkle in Time was only the beginning: here, together for the first time in a deluxe Library of America edition, are the thrilling adventures of Meg Murray's daughter PollyMadeleine L'Engle's A Wri

Library of America inaugurates its edition of the complete fiction of one of America's most beloved living writersPort William, Kentucky, is one of the most fully realized settings in American literat

The violent aftermath of the Civil War comes to dramatic life in this sweeping new collection of firsthand writing There are few periods in American history more consquential but less understood than

For the first time, the complete stories of the master chronicler of tradition and transformation in the twentieth-century South.Born and raised in Tennessee, Peter Taylor was the great chronicler of

For the first time, the complete stories of the master chronicler of tradition and transformation in the twentieth-century South.Born and raised in Tennessee, Peter Taylor was the great chronicler of