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Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

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出版日:2010/12/01 作者:Frank E. Harrell  出版社:Springer Verlag  裝訂:平裝
Many texts are excellent sources of knowledge about individual statistical tools, but the art of data analysis is about choosing and using multiple tools. Instead of presenting isolated techniques, th
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出版日:2010/11/30 作者:Pietro Mantovan; Piercesare Secchi  出版社:Springer Verlag  裝訂:精裝
The last years have seen the advent and development of many devices able to record and store an always increasing amount of complex and high dimensional data; 3D images generated by medical scanners o
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出版日:2010/11/30 作者:Melanie A. Woodin (EDT); Arianna Maffei (EDT)  出版社:Springer Verlag  裝訂:精裝
This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug a
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出版日:2010/06/30 作者:Robert A. Muenchen; Joseph M. Hilbe  出版社:Springer Verlag  裝訂:精裝
Stata is the most flexible and extensible data analysis package available from a commercial vendor. R is a similarly flexible free and open source package for data analysis, with over 3,000 add-on pac
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As we enter the 21st century, there is an urgent need for new approaches to mathematics education emphasizing its relevance in young learners’ futures. Modeling Students’ Mathematical Modeling Compete
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出版日:2009/08/30 作者:Karl W. Broman; Saunak Sen  出版社:Springer Verlag  裝訂:精裝
This book gives an overview of the practical aspects of the analysis of QTL mapping experiments based on inbred line crosses, wtih explicit instructions on the use of the R/qtl software.
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A Primer of Ecology With R
90 折
出版日:2009/07/15 作者:M. Henry H. Stevens  出版社:Springer Verlag  裝訂:平裝
Provides simple explanations of the important concepts in population and community ecology. Provides R code throughout, to illustrate model development and analysis, as well as appendix introducing th
優惠價: 9 3375
無庫存
出版日:2009/06/30 作者:Asli Celikyilmaz; I. Burhan Tnrksen  出版社:Springer Verlag  裝訂:精裝
The objective of this book is to present an uncertainty modeling approach using a new type of fuzzy system model via "Fuzzy Functions". Since most researchers on fuzzy systems are more familiar with t
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This book contains the proceedings of two long-standing workshops: The 10th International Workshop on Business Process Modeling, Development and Support, BPMDS 2009, and the 14th International Confere
出版日:2009/05/10 作者:H. paul Williams  出版社:Springer Verlag  裝訂:精裝
Paul Williams, a leading authority on modeling in integer programming, has written a concise, readable introduction to the science and art of using modeling in logic for integer programming. Written f
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出版日:2008/12/01 作者:Karen Vanderven  出版社:Springer Verlag  裝訂:精裝
Promoting Positive Development in Early Childhood introduces Developmental Assets for Early Childhood, a unique strengths-based framework that identifies the spectrum of positive influences on child d
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出版日:2008/11/01 作者:Longbing Cao (EDT); Philip S. Yu (EDT); Chengqi Zhang (EDT); Huaifeng Zhang (EDT)  出版社:Springer Verlag  裝訂:精裝
Data Mining for Business Applications presents the state-of-the-art research and development outcomes on methodologies, techniques, approaches and successful applications in the area. The contributio
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出版日:2008/08/21 作者:Florian Hahne; Wolfgang Huber; Robert Gentleman; Seth Falcon  出版社:Springer Verlag  裝訂:平裝
Bioconductor software has become a standard tool for the analysis and comprehension of data from high-throughput genomics experiments. Its application spans a broad field of technologies used in cont
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出版日:2007/07/13 作者:Rongling Wu; Changxing Ma; George Casella  出版社:Springer Verlag  裝訂:精裝
The book introduces the basic concepts and methods that are useful in the statistical analysis and modeling of DNA-based marker and phenotypic data that arise in agriculture, forrestry, experimental
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出版日:2007/05/04 作者:Peter Lucas (EDT); Jose A. Gamez (EDT); Antonio Salmeron (EDT)  出版社:Springer Verlag  裝訂:精裝
This book brings together important topics of current research in probabilistic graphical modeling, learning from data and probabilistic inference. Coverage includes such topics as the characterizatio
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Analysing Ecological Data
90 折
出版日:2007/04/20 作者:Alain F. Zuur; Elena N. Ieno; Graham M. Smith  出版社:Springer Verlag  裝訂:精裝
This book provides a practical introduction to analyzing ecological data using real data sets. The first part gives a largely non-mathematical introduction to data exploration, univariate methods (inc
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Analysing Ecological Data
90 折
出版日:2007/04/20 作者:Alain F. Zuur; Elena N. Ieno; Graham M. Smith  出版社:Springer Verlag  裝訂:平裝
This book provides a practical introduction to analyzing ecological data using real data sets. The first part gives a largely non-mathematical introduction to data exploration, univariate methods (inc
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出版日:2005/09/15 作者:Esteban Zimanyi (EDT); Stefano Spaccapietra (EDT)  出版社:Springer Verlag  裝訂:平裝
The LNCS Journal on Data Semantics is devoted to the presentation of notable work that, in one way or another, addresses research and development on issues related to data semantics. Based on the high
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Elements of Multivariate Time Series Analysis
90 折
出版日:2003/11/01 作者:Gregory C. Reinsel  出版社:Springer Verlag  裝訂:平裝
Now available in paperback, this book introduces basic concepts and methods useful in the analysis and modeling of multivariate time series data. It concentrates on the time-domain analysis of multiva
優惠價: 9 3150
無庫存
出版日:2003/08/01 作者:Michael K. Pugsley (EDT)  出版社:Springer Verlag  裝訂:精裝
A comprehensive survey of the latest therapeutic drug discoveries in cardiac and cardiovascular medicine and of the most recent breakthroughs in molecular cardiology. The authors describe the most adv
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出版日:2002/06/01 作者:Michael Hayes (EDT); Giuseppe Saccomandi (EDT)  出版社:Springer Verlag  裝訂:平裝
More than fifty years ago, Professor R. S. Rivlin pioneered developments in both the theory and experiments of rubber elasticity. These together with his other fundamental studies contributed to a rev
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出版日:2000/06/01 作者:Rita Aggarwala; N. Balakrishnan  出版社:Springer Verlag  裝訂:精裝
This new book offers a guide to the theory and methods of progressive censoring. In many industrial experiments involving lifetimes of machines or units, experiments have to be terminated early. Progr
出版日:1999/12/01 作者:Michael L. Deaton; James J. Winebrake  出版社:Springer Verlag  裝訂:精裝
Dynamic Modeling of Environmental Systems is a primer on using models to understand environmental problems. With their many natural, economic, political, and technical aspects, environmental problems
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出版日:2018/06/15 作者:Lyn English (EDT); Tamara Moore (EDT)  出版社:Springer Verlag  裝訂:精裝
This book addresses engineering learning in early childhood, spanning ages 3 to 8 years. It explores why engineering experiences are important in young children's overall development and how engineeri
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Urban Air Pollution Monitoring by Ground-based Stations and Satellite Data ― Multi-season Characteristics from Lanzhou City, China
90 折
出版日:2018/05/24 作者:Mikalai Filonchyk; Haowen Yan  出版社:Springer Verlag  裝訂:精裝
This book examines air pollution of a big city using multi-year and multi-season data from ground-based air monitoring stations and satellite sounding data, which provides more clear and detailed info
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The Nature of Variation in Tone Sandhi Patterns of Shanghai and Wuxi Wu
90 折
出版日:2017/10/27 作者:Hanbo Yan  出版社:Springer Verlag  裝訂:精裝
This book conducts a thorough investigation of the variation in tone sandhi patterns of Shanghai and Wuxi Wu using quantitative rating experiments. Although Shanghai Wu has been well documented, to da
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Leader Development Deconstructed
90 折
出版日:2017/10/20 作者:Matthew G. Clark (EDT); Craig W. Gruber (EDT)  出版社:Springer Verlag  裝訂:精裝
This book examines both academic and practical theories relating to leader development. It broadens the scope of this topic by including data-driven theory and proposals from diverse areas that are ei
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Nonlinear Reaction-Diffusion Systems ─ Conditional Symmetry, Exact Solutions and Their Applications in Biology
90 折
出版日:2017/09/19 作者:Roman Cherniha; Vasyl Davydovych  出版社:Springer Verlag  裝訂:平裝
This book presents several fundamental results in solving nonlinear reaction-diffusion equations and systems using symmetry-based methods. Reaction-diffusion systems are fundamental modeling tools for
優惠價: 9 1637
無庫存
Geomorphology of Lake-Catchment Systems ─ A New Perspective from Limnogeomorphology
90 折
出版日:2017/08/03 作者:Kenji Kashiwaya  出版社:Springer Verlag  裝訂:精裝
This book presents the study of limnogeomorphology, in which past proxy data such as lacustrine sediments with information on landform development can be linked to modern observed data acquired by ins
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出版日:2017/06/28 作者:Jim Ramsay; Giles Hooker  出版社:Springer Verlag  裝訂:精裝
This text focuses on the use of smoothing methods for developing and estimating differential equations following recent developments in functional data analysis and building on techniques described in
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Isotropic and Anisotropic Seismic Tomography Using Active Source and Earthquake Records
90 折
出版日:2017/06/26 作者:Yu-Pin Lin  出版社:Springer Verlag  裝訂:精裝
This book presents investigations on the Earth's seismic structure using both active-source and natural earthquake records. It discusses the ground-truth data obtained from the TAiwan Integrated
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Linear-dynamical Quantum Systems ― Analysis, Synthesis, and Control
90 折
出版日:2017/05/22 作者:Hendra Nurdin; Naoki Yamamoto  出版社:Springer Verlag  裝訂:精裝
This monograph provides an in-depth treatment of the class of linear-dynamical quantum systems. The monograph presents a detailed account of the mathematical modeling of these systems using linear alg
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Shale Analytics ― Data-driven Analytics in Unconventional Resources
90 折
出版日:2017/02/13 作者:Shahab D. Mohaghegh  出版社:Springer Verlag  裝訂:精裝
This book describes the application of modern information technology to reservoir modeling and well management in shale. While covering Shale Analytics, it focuses on reservoir modeling and production
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Unconventional Conflict ― A Modeling Perspective
90 折
出版日:2017/02/10 作者:Dean S. Hartley III  出版社:Springer Verlag  裝訂:精裝
This book describes issues in modeling unconventional conflict and suggests a new way to do the modeling. It presents an ontology that describes the unconventional conflict domain, which allows for g
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Luxury Fashion Retail Management
90 折
出版日:2016/12/16 作者:Tsan-ming Jason Choi (EDT); Bin Shen (EDT)  出版社:Springer Verlag  裝訂:精裝
Using various research methodologies, such as reviews, case studies, analytical modeling and empirical studies, this book investigates luxury fashion retail management and provides relevant insights,
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Interactive Modeling and Simulation in Business System Design (Simulation Foundations, Methods and Applications)
90 折
出版日:2016/12/13 作者:Ella Roubtsova  出版社:Springer Verlag  裝訂:精裝
This book explores the process of interactive modeling and interactive simulation. The text covers several modeling techniques that are used in the interactive cycle of modeling and simulation. There
優惠價: 9 2565
無庫存
出版日:2016/11/04 作者:George Danko  出版社:Springer Verlag  裝訂:精裝
This work provides an enormous contribution to the broad effort of modeling heat, mass and momentum transport in multi-physics problems with the development of new solution approaches. It re-visits th
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Pharmacokinetics in Drug Development ― Problems and Challenges in Oncology
90 折
出版日:2016/10/13 作者:Peter L. Bonate (EDT); Danny R. Howard (EDT)  出版社:Springer Verlag  裝訂:精裝
In this volume, the specific challenges and problems facing the evaluation of new oncology agents are explored with regards to pharmacokinetic, pharmacodynamic modeling and clinical pharmacology devel
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Voting Experiments
90 折
出版日:2016/10/11 作者:Andre? Blais (EDT); Jean-fran?s Laslier (EDT); Karine Van Der Straeten (EDT)  出版社:Springer Verlag  裝訂:精裝
?This book presents a collection of papers illustrating the variety of "experimental" methodologies used to study voting. Experimental methods include laboratory experiments in the tradition of politi
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Uncertain Portfolio Optimization
90 折
出版日:2016/10/04 作者:Zhongfeng Qin  出版社:Springer Verlag  裝訂:精裝
This book provides a new modeling approach for portfolio optimization problems involving a lack of sufficient historical data. The content mainly reflects the author’s extensive work on uncertainty po
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