Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

In print since the 1950s, the Mushroom Planet series is back with a new design by illustrator Kevin Hawkes. Don t miss the adventures of Chuck and David, two boys who travel to the alien planet Basidi

Did you know that ants have jobs? Ants may not look like they are doing anything important, but each ant that lives in a hill has a special job, whether it is cleaning the nest, digging new tunnels or

''Pratchett''s writing is a constant delight'' Daily MailTHE COMPANY BUILDS PLANETS.Kin Arad is a high-ranking official of the Company. After twenty-one decades of living, and with the help of memory surgery, she is at the top of her profession. Discovering two of her employees have placed a fossilized plesiosaur in the wrong stratum, not to mention the fact it is holding a placard which reads, ''End Nuclear Testing Now'', doesn''t dismay the woman who built a mountain range in the shape of her initials during her own high-spirited youth.But then came discovery of something which did intrigue Kin Arad. A flat earth was something new...

Spinoza's theoretical philosophy is one of the most radical attempts to construct a pure ontology with a single infinite substance. This book, which presents Spinoza's main ideas in dictionary form, h

美式黃色校車是美國學童上下學最主要的交通工具，在【魔法校車系列】中，黃色的老校車卻成了一輛飛天遁地、上山下海的潛水艇、飛機，甚至是穿越北極圈的雪橇……，載著麻辣魔法女教師及其精怪頑皮的小學班級歷經一場又一場天翻地覆、驚心動魄又刺激精采的自然科學大探索！ When Ms. Frizzle, the strangest teacher in school, takes her class on a

Shortly before his death in 1984, Michel Foucault spoke of an idea for a new book on "technologies of the self." He described it as "composed of different papers about the self...,about the role of re

Intonation in Context is for upper-intermediate and advanced learners of English who want to improve their intonation. It aims to make learners aware of the main features of intonation and provides en

The chameleon's life was not very exciting until the day it discovered it could change not only its color but its shape and size,too. When it saw the wonderful animals in the zoo, it immediately wante

Summertime. It's hot enough to fry an egg on the sidewalk. Richard "Beast" Best and Matthew Jackson can't wait to dive into Emily Arrow's cool blue pool. But when they get there, Mrs. Arrow tells them that Emily has gone off to summer school.Summer school! How could they forget? That's exactly where they should be right now. Sitting in class, Beast still thinks summertime is the best time, and he and Matthew can always go swimming in the afternoon. But then Matthew gives Beast some bad news. It's up to Beast to think of a way to help Matthew fast--before the summer is ruined.

From the excitement of arrival to the wonder of taking off -- a picture book that captures in joyous and powerful images all the magic of an airport.

Caps for Sale is a timeless classic, in print for over fifty years, and beloved by generations of readers. This easy-to-read story about a peddler and a band of mischievous monkeys is filled with warm

十二歲的克勞蒂雅為了讓爸媽重視自己，決定離家出走，躲進大都會博物館。她帶著弟弟一起，卻在館內發現一尊神祕雕像，決心查出它的真相。這部小說結合博物館探險、輕鬆推理與成長觀察，是紐伯瑞獎經典之作，至今仍深受讀者喜愛。A Time Best YA Book of All Time (2021)Run away to the Metropolitan Museum of Art with E. L. Konigsburg’s beloved classic and Newbery Medal­–winning novel From the Mixed-Up Files of Mrs. Basil E. Frankweiler!When Claudia decided to run away, she planned very carefully. She would be gone just long enough to teach her parents a lesson in Claudia appreciation. And she would go in comfort-she would live at the Metropolitan Museum of Art. She saved her money, and she invited her brother Jamie to go, mostly because be was a miser and would have money.Claudia was a good organizer and Jamie bad some ideas, too; so the two took up residence at the museum right on schedule. But once the fun of settling in was over, Claudia had two unexpected problems: She felt just the same, and she wanted to feel different; and she found a statue at the Museum so beautiful she could not go home until she

"This book...recounts the persistence of a Frenchman, Louis Bleriot, to build a flying machine to cross the English Channel.... The text is succinct, caption-like in its directness and brevity....The

Robert Kraus poses some leading questions and skillfully guides "Mouse" to answers that culminate in a decidedly satisfying ending. Mouse's experience unfolds with the validity and charm of a nursery

"Lectures on Philosophical Theology is an indispensable addition to Kant's works in English. It has not been previously translated, and even though it is compiled from lecture notes, it provides infor

What do you say when: you bump into a crocodile on a crowded city street? a nice gentleman introduces you to a baby elephant? the Queen feeds you so much spaghetti that you don't fit in your c

The kids in Room 207 decide to act up while their teacher, Miss Nelson, is away until they discover that her substitute will be the horrible Miss Viola Swamp

小時候，愛麗絲許下心願：長大後要旅行、住在海邊，還要為這個世界增添美麗。這本經典繪本講述她如何用行動實現承諾，把魯冰花的種子撒滿沿岸，讓世界因她而不同。細膩插圖與溫暖故事，代代流傳。Alice made a promise to make the world a more beautiful place, then a seed of an idea is planted and blossoms into a beautiful plan. This beloved classic and celebration of nature—written by a beloved Caldecott winner—is lovelier than ever!Barbara Cooney's story of Alice Rumphius, who longed to travel the world, live in a house by the sea, and do something to make the world more beautiful, has a timeless quality that resonates with each new generation. The countless lupines that bloom along the coast of Maine are the legacy of the real Miss Rumphius, the Lupine Lady, who scattered lupine seeds everywhere she went. Miss Rumphius received the American Book Award in the year of publication.The illustrations have been reoriginated, going back to the original art to ensure state-of-the-art reproduction of Cooney's exquisite artwork. The art for Miss Rumphius has a permanent home in the Bowdoin College

小時候，愛麗絲許下心願：長大後要旅行、住在海邊，還要為這個世界增添美麗。這本經典繪本講述她如何用行動實現承諾，把魯冰花的種子撒滿沿岸，讓世界因她而不同。細膩插圖與溫暖故事，代代流傳。Alice made a promise to make the world a more beautiful place, then a seed of an idea is planted and blossoms into a beautiful plan. This beloved classic and celebration of nature—written by a beloved Caldecott winner—is lovelier than ever!Barbara Cooney''s story of Alice Rumphius, who longed to travel the world, live in a house by the sea, and do something to make the world more beautiful, has a timeless quality that resonates with each new generation. The countless lupines that bloom along the coast of Maine are the legacy of the real Miss Rumphius, the Lupine Lady, who scattered lupine seeds everywhere she went. Miss Rumphius received the American Book Award in the year of publication.The illustrations have been reoriginated, going back to the original art to ensure state-of-the-art reproduction of Cooney''s exquisite artwork. The art for Miss Rumphius has a permanent home in the Bowdoin Colle

The topic of controversy in Time Magazine, Esquire, and numerous other publications across the country, Pyramid Power has captured the imagination of millions all over the world who have used these my

WINNER OF THE CALDECOTT MEDALThe classic tale of a never-to-be-forgotten summer!Out on the islands that poke their rocky shores above the waters of Penobscot Bay, you can watch the time of the world go by, from minute to minute, hour to hour, from day to day. . .So begins this classic story of one summer on a Maine island from the author of One Morning in Maine and Blueberries for Sal. The spell of rain, the gulls and a foggy morning, the excitement of sailing, the quiet of the night, the sudden terror of a hurricane, and, in the end, the peace of the island as the family packs up to leave are shown in poetic language and vibrant, evocative pictures.

Do you remember your first realization of any of your five senses? Prolific children's author J. M. ParramA3n successfully tackles these tough concepts in words that 3-5 year olds can comprehend. The

This piano score represents a reduction of the orchestral version of Tchaikovsky's famous ballet. Headings are in Russian and French. 275 pages, 7 by 10 ? inches.

A proud caterpillar and a curious polliwog become unlikely friends in this delightful Classic Board Book by beloved author, illustrator, and cartoonist Jack Kent!Down by the pond there lived a caterpi

This volume reproduces, from the authoritative Breitkopf & Härtel edition, three of Brahms' great orchestral favorites. Editor's commentary in German and English.

Proven educational methods reinforce what is taught in preschool through the elementary grades. Simple instructions and delightful graphics motivate your child to master the skills...and turn the page

Illus. in full color. "Sick of being a bunny, P. J. Funnybunny takes off to become a bear. Hibernation gets dull, so he tries being a bird. And so it goes, with beavers, pigs, possums, and skunks--til

“This is the kind of picture book that you can return to again and again, for as pretty as it is it’s better than pretty; it’s true in a way that moves children and grown-ups alike.”—New York Times Bo

Morris the moose can't count gumdrops, so he decides to go to school. He is thrilled after a day in the classroom?he can finally count candy. Now he can buy gumdrops!

PHarold Bloom's selection of Pater's writings brings together in one volume the most important sections and passages from iThe Renaissance, Imaginary Portraits, Appreciations, Plato and Platonism, Gre

This Hackett edition, first published in 1981, is an unabridged and unaltered republication of the seventh (1907) edition as published by Macmillan and Company, Limited. From the forward by John Rawl

With his magic purple crayon, Harold draws himself into a rocket voyage to Mars, then safely back to earth just in time for breakfast.

Drawings prepared in pastels, watercolors, and acrylics highlight a collection of informative vignettes describing a variety of customs and traditions practiced by different African peoples

Tongue twisters abound in this classic Dr. Seuss Beginner Book!“Bed Spreaders spread spreads on beds.Bread Spreaders spread butter on breads.And that Bed Spreader better watch out how he’s spreading…o

When Strega Nona leaves him alone with her magic pasta pot, Big Anthony is determined to show the townspeople how it works in this classic Caldecott Honor book from Tomie dePaola. Strega Nona—"Grandm

Ever since the rise of science and the scientific method in the seventeenth century, we have rejected mythology as the product of superstitious and primitive minds. Only now are we coming to a fuller

The four members of the Private Eyes Club?Skinny, Wizard, Snitch, and Tubby?solve the baffling case of the missing cat. ?Will keep new readers in suspense right up to the satisfying conclusion.? ?H.

"In this Caldecott Medal winner, Mosquito tells a story that causes a jungle disaster. "Elegance has become the Dillons' hallmark. . . . Matching the art is Aardema's uniquely onomatopoeic text . . .

In his discussion of natural theology (arguments to prove the existence of God) and natural atheology (arguments for the falsehood of theistic belief) Plantinga focuses on two of the traditional argum

A true classic with a timeless message, The Story of Ferdinand has enchanted readers since it was first published in 1936. All the other bulls would run and jump and butt their heads together. But Ferdinand would rather sit and smell the flowers. So what will happen when our pacifist hero is picked for the bullfights in Madrid? This new edition contains the complete original text of the story and the original illustrations with watercolor tones added.