Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Pull out the sliding tray in the cover to reveal removable, double-sided fruit characters. Little ones will love following the clues to match the correct board piece to each page! Do you know which fruit grows in pairs? And which can take up to 3 years to grow?With simple facts to share along the way, this is the perfect book to encourage balanced, healthy eating habits through play. An interactive guessing game and early learning board book in one!

Introduce numbers 1 to 5 with The Very Hungry Caterpillar in this playful lift-the-flap early learning series!Count along with The Very Hungry Caterpillar and discover two leaping frogs, three colourful fish and more bright and bold animal friends!Each page of this chunky board book has been thoughtfully designed with a peep-through flap to encourage little ones to join in and finish the number sequence. Perfect for getting very little ones excited about learning their very first numbers!Discover more early learning books with The Very Hungry Caterpillar:Colours: Learn and Play with The Very Hungry CaterpillarThe Very Hungry Caterpillar Eats Dinner: A shapes bookThe Very Hungry Caterpillar's First 100 WordsThe Very Hungry Caterpillar's First 100 AnimalsThe Very Hungry Caterpillar's Touch-and-Feel Animals

Introduce first colours with The Very Hungry Caterpillar in this playful lift-the-flap early learning series!Read along with The Very Hungry Caterpillar and discover bright and colourful animal friends!Each page of this chunky board book has been thoughtfully designed with a peep-through flap to encourage little ones to join in and guess the colour. Perfect for getting very little ones excited about learning their very first colours!Discover more early learning books with The Very Hungry Caterpillar:123: Learn and Play with The Very Hungry CaterpillarThe Very Hungry Caterpillar Eats Dinner: A shapes bookThe Very Hungry Caterpillar's First 100 WordsThe Very Hungry Caterpillar's First 100 AnimalsThe Very Hungry Caterpillar's Touch-and-Feel Animals

Learn why the wind blows with the help of The Very Hungry Caterpillar!In this nonfiction story, young readers will discover what makes the wind whoosh around them. The wonders of nature come to life in this early-learning series centered around weather, featuring simple text and Eric Carle's classic illustrations!

Join Spot and learn about colours, shapes, first words and counting!Spot's First Little Library is a sweet collection of four chunky mini board books. Each book features a different key early learning concept - colours, words, shapes and counting. With sturdy pages and a handy slipcase to keep the books together, this charming set is perfect for the littlest Spot fans!Eric hill's Where's Spot was the first ever lift-the-flap book - and his groundbreaking innovation continues to delight and surprise readers with interactive fun.Spot has now been a trusted character in early learning for over 40 years, selling over 65 million books worldwide. Loved this? Try these:Where's Spot?Find Spot at the ZooFind Spot at the MarketFind Spot: A Sporty DaySpot Bakes a CakeSpot and Friends

Honey is waiting to see Doctor Bingo, but some of the other patients the doctor needs to see are in a real pickle! Receptionist Bluey reassures Honey she’ll definitely be seen soon.Will Honey ever get a turn?"Edna, hold my appointments!"Join Bluey and Bingo in this hilarious picture book.Don’t miss these other awesome Bluey books:Bluey: FairytaleBluey: TrainsBluey: BedroomBluey is an Emmy award-winning Australian children's television programme following the adventures of a loveable six-year-old Blue Heeler Puppy, Bluey and her family. It’s currently showing on Disney+, BBC iPlayer and CBeebies in the UK. Bluey enjoys exploring the world and using her imagination to turn everyday life into an amazing adventure. Join Bluey in this fun collection of story, activity and novelty books that celebrate play.

Help Stick Man run and wriggle his way back to his family in this super soft and fabulously interactive finger puppet book. One day he wakes early and goes for a jogStick Man, oh Stick Man,Beware of the dog!Help Stick Man run and wriggle his way back to his family in this super soft and fabulously interactive finger puppet book.One day he wakes early and goes for a jog.Stick Man, oh Stick Man,Beware of the dog!Story based on the bestselling Stick Man by Julia Donaldson and Axel Scheffler.With Julia's classic rhyme and a fun finger puppet based on Axel's fabulous illustrations, children will love helping Stick Man make his way back home.The perfect introduction to Julia and Axel's gorgeous storytelling world, this edition is great for little readersIf you liked this, check out the Zog and Superworm finger puppet books!

Learn why it snows with the help of The Very Hungry Caterpillar!In this nonfiction story, young readers will discover what makes snow fall. The wonders of nature come to life in this early-learning series centered around weather, featuring simple text and Eric Carle's classic illustrations!

Learn why it gets hot outside with the help of The Very Hungry Caterpillar!In this nonfiction story, young readers will discover what makes hot weather happen. The wonders of nature come to life in this early-learning series centered around weather, featuring simple text and Eric Carle's classic illustrations!

Get into gear and learn all about vehicles in this addition to the bestselling Abrams Block Book series! Learn about all the things that go, go, go in this fun addition to the acclaimed Abrams Block Book series! In this small but sturdy block-shaped board book, young readers are introduced to an incredible array of vehicles big and small. From airplanes, buses, and cars to subways, rail trains, and unicycles, follow our protagonists as they travel using human-powered and motor-powered vehicles alike to get to their destination: a hot air balloon ride that overlooks a constantly in-motion town! Like other books in the Block Book series, Go!Block features die-cut shapes on every spread and has durable, interactive gatefolds, perfect for curious hands. Illustrated in Peski Studio's bright, graphic style, this is a must-have book for transportation enthusiasts everywhere. Collect the whole series: Alphablock * Countablock * Dinoblock * Cityblock * Buildablock * Farmblock * Loveblock * Shar

9781839948435 Baby Faces: Little Tiger, Where Are You?Find your baby's face in this delightful new lift-the-flap book with a mirror on every page! One thing is for sure - babies love mirrors! This brand new series of board books aims to enhance early mirror play as very young children will enjoy finding their own face on every page. Featuring large card flaps with friendly animals which are easy for even the littlest hands to grab, babies will enjoy reaching for these books again and again. Scan the QR code on the back cover to join in with the playful rhyming song based on the classic 'Finger Family' rhyme! Other books in the series include: Little Bear, Little Dog and Little Owl9781839948442 Baby Faces: Little Owl, Where Are You?Find your baby's face in this delightful new lift-the-flap book with a mirror on every page! One thing is for sure - babies love mirrors! This brand new series of board books aims to enhance early mirror play as very young children will enjoy findin

Ring! Ring! Who's there? Interact with the clever sliders, flaps, and mirror in this book to imitate using phone applications! This phone-shaped book encourages imaginative play as children act out zooming into photographs, checking the weather, and more.開箱影片https://www.makebelieveideas.com/qr-animations/11637-BB01-01-QR.mp4

Find your baby's face in this delightful new lift-the-flap book with a mirror on every page! One thing is for sure - babies love mirrors! This brand new series of board books aims to enhance early mirror play as very young children will enjoy finding their own face on every page. Featuring large card flaps with friendly animals which are easy for even the littlest hands to grab, babies will enjoy reaching for these books again and again. Scan the QR code on the back cover to join in with the playful rhyming song based on the classic 'Finger Family' rhyme! Other books in the series include: Little Bear, Little Dog and Little Tiger

Learn your numbers and counting with the bravest girl in the world, Madeline!Ludwig Bemelmans's beloved character Madeline is back, and here to teach young readers how to count. Using familiar faces and settings from the classic and beloved Madeline books, readers will delight in learning how to count 1 through ten with Madeline!Series Overview: Love from Madeline (mini-HC) - Fall 2021Madeline's ABCs (board) - Summer 2022Madeline's 123 (board) - Fall 2022Untitled Madeline! (mini-HC) - Fall 2022Untitled Board Book - Spring 2023

From the #1 science author for kids comes this next installment in the best-selling Baby University seriesWith scientific and mathematical information from an expert, The ABCs of Geography is the perfect book for enlightening the next generation of geniuses. Written by an expert, this is the perfect book for enlightening the next generation of geniuses. It's never too early to become a mathematician

These cute pups are in big trucks and ready to dig! Book two of this original board book series is perfect for toddlers with big building dreams.Dig Doug, Puddles, and Cheddar are ready for a big day at puppy school. Today they have an extra big project―using their construction trucks to dig a swimming pool! Dig Doug is so happy because Dig Doug LOVES to dig. But when he digs a bit too deep, his puppy friends must figure out a plan to save him.

Discover the wonders of the universe in this amazing, fact-packed book! What can YOU see in space? This fun and chunky board book features bite-size facts and accessible information to engage even the youngest of readers. Toddlers will love peeping through the cut-out pages to journey through outer space! With bright, bold illustrations and endless hidden details to spot, this is the perfect first introduction to space. What Can You See? In Space is part of an early non-fiction series for curious toddlers.Each book is packed with fun facts and peep-through pages to engage little learners. Also available in the series: What Can You See? On the Farm, What Can You See? At Night, What Can You See? On the Building Site

The perfect baby present and self-purchase for just the right moment in a baby and parent's life.Welcome to Beginning Baby, a line of novelty board books and gifts designed to give little ones a bright start! Vetted by early childhood experts and thoughtfully created with input from parents and caregivers, each Beginning Baby book explores educational concepts tied to early learning milestones, building a foundation for a strong beginning. An adorable and energetic cast of animal characters guide babies through early learning concepts in a playful way that reinforces ideas through rhythm and repetition and engages eyes and hands with flaps, moving parts, mirrors, or tabs. With its irresistible interactive elements, colorful and decorative designs, and strong educational framework, Beginning Baby makes growing and learning for babies as easy as playing and dreaming―and also makes the perfect gift for new families.The beloved song "Head, Shoulders, Knees, and Toes" comes to life in this

An early storybook for toddlers, with slide and find mechanisms by bestselling illustrator Jo Lodge.

An early storybook for toddlers, with slide and find mechanisms by bestselling illustrator Jo Lodge.

Exciting series of vibrant neon lift-the-flap board books introducing the concept of familyFind out the different names for mummy and daddy animals by the river – and then lift the big, sturdy flaps to find the babies, with a double flap and peekaboo holes on the final spread! A striking, satisfying introduction to animal families from printmaker Jane Ormes, with eye-catching artwork using bold neon ink to capture the attention and imagination of babies and toddlers.Other titles in the series include: Farm, Safari, Jungle, Forest and Snow

A bright, fun first concepts book featuring sweet mice characters and simple, yet clever die-cuts to explain the concept of opposites. In this innovative die-cut title, children will learn the concept of opposites through bright, fun illustrations featuring Little Mouse and other friendly animal characters.The peep-through holes help children engage with the title and encourage sensory development and exploration.This is the first title in a series of first concept books in the Little Mouse Learns series:Book 1: OPPOSITESBook 2: COLOURSBook 3: SHAPESBook 4: NUMBERS

A bright, fun first concepts book featuring sweet mice characters and simple, yet clever die-cuts to explain the concept of shapes. In this innovative die-cut title, children will learn the concept of shapes through bright, fun illustrations featuring Little Mouse and other friendly animal characters.The peep-through holes help children engage with the title and encourage sensory development and exploration, and bold colours bring these books to life.This is the first title in a series of first concept books in the Little Mouse Learns series:Book 1: OPPOSITESBook 2: COLOURSBook 3: SHAPESBook 4: NUMBERS​These board books are great for young children as they introduce them to these basic but important concepts in a friendly, fun and accesible way!

A bright, fun first concepts book featuring sweet mice characters and simple, yet clever die-cuts to explain the concept of shapes. In this innovative die-cut title, children will learn the concept of shapes through bright, fun illustrations featuring Little Mouse and other friendly animal characters.The peep-through holes help children engage with the title and encourage sensory development and exploration, and bold colours bring these books to life.Four first concept books in the Little Mouse Learns series:Book 1: OPPOSITESBook 2: COLOURSBook 3: SHAPESBook 4: NUMBERS

It's never too early to get little ones interested in science! Discover over 100 beautifully illustrated first STEM words to share with little learners.

Spencer the cat stars in another die-cut board book, introducing young children to what happens at school, including early vocabulary.In Spencer Goes to School Spencer is starting his first day of pre-school! Follow along as Spencer packs his backpack, meets his teacher, makes new friends, plays on the playground, and more!

No racing in the haul-ways! From the late, beloved author Amy Krouse Rosenthal, a look at seven adorable train cars on their first day of school.All aboard the train-car pool! A new lineup of students is off and rolling to Choo-Choo School. After reciting their classroom rules ― Work hard, play fair, be kind ― it’s time for some math to get the wheels turning. Then everyone’s ready to climb a hill in gym (it’s good to blow off steam), sing songs in music (Flat Car is a bit off-key), and learn the whole alphabet, especially the letter R. In one of Amy Krouse Rosenthal’s last books, lighthearted verse portrays a world where train stations are classrooms, the conductor doubles as the teacher, and Boxcar is happy to hand out tissues to anyone who ah-choo-choos. Bright, energetic illustrations by animation artist Mike Yamada bring the whole clickety crew to rollicking life.

Learn how a seed becomes a tree with Eric Carle’s classic artwork!In this nonfiction story, young readers explore the transformation of a seed into a tree. The miracles of nature come to life in this early-learning series centered around life cycles, featuring simple text and Eric Carle’s classic illustrations!

Learn how a tadpole becomes a frog with Eric Carle’s classic artwork!In this nonfiction story, young readers explore the transformation of a tadpole into a frog. The miracles of nature come to life in this early-learning series centered around life cycles, featuring simple text and Eric Carle’s classic illustrations!

In this exciting new series of construction books for kids, we invite toddlers to learn how to build some of their favorite things! From using screws to set up the slide and a drill to set up the tunn

In this exciting new series of construction books for kids, we invite toddlers to learn how to build some of their favorite things! From using an auto level to survey the roadway to pouring the concre

Everyone loves Little Lamb, but where is she hiding? Very young children will love to seek and find Little Lamb by lifting the five sturdy flaps in this chunky board book that promotes language development, fine motor skills, and interaction. Seek and find lift-the-flap fun for little ones!

A book that helps toddlers adjust to using the potty in a fun and comfortable way. A charming and entertaining board book that helps toddlers adjust to using the potty in a fun and relatable way. Meet twins Johnny and Jasmine. It's time they started to try and use a potty and to wear pants. They HAVE pants, but Johnny just puts his on Teddy while Jasmine uses her potty as a slide for her toys! Follow along with the funny story as Johnny and Jasmine go through the ups and downs of their potty training journey, from getting comfortable with a potty, to positive reinforcement, hygiene, and understanding that accidents happen. Packed with handy tips and charming illustrations, Time To Use The Potty is the perfect way to introduce toilet training to your little one. Potty training has never been so easy - or so much fun!

These chunky board books provide your toddler with on-the-go learning that will help develop language skills and early literacy. The perfect size for little hands!The My First Library line focuses on

These chunky board books provide your toddler with on-the-go learning that will help develop language skills and early literacy. The perfect size for little hands!The My First Library line focuses on

Do you want to be a doctor? Find out what it's like to help people feel better in this inspiring board book that features a peek-through cover and surprise mirror ending This fourth book in the I Want to Be... series invites curious little ones to imagine themselves as doctors, from putting on a doctor's outfit and riding in an ambulance to using a stethoscope and X-ray machine to help their patients. Its positive tone and reassuring message can help ease anxiety around a child's first trip to the doctor, and the surprise mirror at the end provides a fun, interactive bonus

Perfect for early learning, this fun board book in the Little Sumo series, from the creator of the Little Kunoichi series, features sumo wrestlers that introduce children to the concept of opposites,

Perfect for early learning, this fun board book in the Little Sumo series, from the creator of the Little Kunoichi series, features sumo wrestlers that introduce children to counting and shares elemen

Have you ever thought about bringing your dragon to the library? Don't do it! You might have the best intentions, but that dragon will cause nothing but trouble. Using rhyming text and a diverse cast

Touch and Feel Colours introduces young children to their first colours, using beautiful illustrations of everyday objects and touch-and-feel novelties to make the colours stand out on every spread. T