本書是美籍台人知名國際生技醫學家陳振炎博士的英文自傳。這位來自台中的台灣囡仔，出生於1940 年代日據時代，幼年四歲喪母，爾後經歷病痛、貧困、戰爭，看遍人生百態，在窮困中的年代卻積極奮鬥；在東海大學結識了相知一生的靈魂伴侶──後來成為陳夫人的陳阮明珠（Pearl Chen），兩人秉持著對生物醫學的喜愛，開啟了一生亦師亦友的人生樂章。陳振炎博士台大醫學院畢業後，取得美國北卡羅來納大學教堂山分校（UNC）醫學院深造的機會，夫妻倆在美國生醫界取得許多重要的生物醫學專利，兩人在世界一流的醫學研究機構──美國國立衛生研究院 （NIH）──與頂尖的醫生和研究人員一起工作，以改善人類健康，創造福祉為己任。“Game Changer”一詞來自一個科學實驗。如果一項實驗不起作用，則重新設計實驗並再次進行，直到實驗有效。實驗中的變化可以說是“改變遊戲規則”。就像中國的老諺語：“天助自助者也！”""Life for a young Taiwanese boy growing up in a Japanese-controlled country in the 1940s was not easy. He was certainly not born with a silver spoon in his mouth. At a vulnerable age of only four, he would lose his mother to a skin infection that in today’s world would have been easily treated with a trip to the doctor’s office. War, poverty, and the daily struggle to survive would set the stage for a real life Cinderella story complete with a harsh stepmother, a fairy godmother, and a beautiful princess who would transform his world.This is the awe-inspiring life story of Dr. Michael Cheng-Yien Chen
