This volume discusses methods for the study of multipotent and pluripotent stem cells of the hair follicle. The stem cells described are involved in both the growth of the hair follicle and its produc
This volume presents latest techniques, protocols, and methodologies for the further study into unconventional protein secretion (UPS). Chapters detail conventional and unconventional secretory pathwa
This volume highlights the molecular and cellular methods used in studying CML pathogenesis and stem cell biology. Written in the highly successful Methods in Molecular Biology series format, chapters
The Zebrafish: Genetics, Genomics, and Transcriptomics, Fourth Edition, is the latest volume in theMethods in Cell Biology series that looks at methods for the analysis of genetics, genomics, and tran
This volume provides a variety of protocols to analyze various epigenetic changes, including differential expression of non-coding RNAs, changes in DNA methylation, and histone modifications in p
This volume presents methods and techniques to study oogenesis in a broad range of organisms, from plants to mammals.Oogenesis: Methods and Protocols guides readers through protocols on models of deve
This book provides a practical and self-contained overview of the Gene Ontology (GO), the leading project to organize biological knowledge on genes and their products across genomic resources. Written
This volume provides an up-to-date compilation of current methodological approaches utilized for the exploration of nucleolar structure and function.Chapters cover a diversity of protocols that includ
This volumepresents detailed laboratory protocols regarding the three major routetechnologies luciferases, efficient opticalprobes, and applications to visualizing molecular events in living subjects.
This volume focuses on the cell biology and physiology of skeletal muscle regeneration. This Book is a collection of classic and cutting edge protocols optimized for mice, but in most cases adaptable
This volume highlights the role of proteostasis in human health and associated disease model systems.Proteostasis: Methods and Protocols guides readers through the latest protocols to study and target
The Zebrafish: Cellular and Developmental Biology: Part B, Fourth Edition, the second volume on the topic in the Methods in Cell Biology series, looks at methods for analyzing cellular and development
This book provides coverage, methodology, and laboratory protocols on the more essential aspects of protein tyrosine phosphatase (PTP) function and regulation, including the use of standardized in vit
This volume is a collection of detailed protocols describing state-of-art approaches that will facilitate the understanding of protein homeostasis in plant stress responses and development.Plant Prote
Presenting topics from the basic application of moleculargenetics to more complex gene expression analysis using different models ofstudy, this detailed volume explores asthma through the lens of gene
This volume provides current methods and protocols for gene and protein delivery based on both lentivirus-generated and spontaneously released nanovesicles. Lentiviral Vectors and Exosomes as Gen
This detailed volume includes a rich variety of applications using various instrumentations, probes, disease models, and targets in order to account for the multidisciplinary nature of the use of in v
The Zebrafish: Cellular and Developmental Biology Part A, Fourth Edition, is the latest edition in the Methods in Cell Biology series that looks at methods for analyzing cellular and developmental bio
This second edition expands on the first edition with new chapters describing methods for studying cell movement, molecular components involved in chemotaxis, spatiotemporal dynamics of signaling comp
This volume presents a series of protocols and methods, some of which are not widely used by researchers/practitioners, and will aid in the execution of different laboratory techniques.Forensic DNA Ty
This second edition expands upon the previous volume with new and updated chapters.Auditory and Vestibular Research: Methods and Protocols, Second Edition guides readers through protocols on cell cult
The aim of this volume is to present current methodologies to predict and understand the pathogenesis of Type-1 Diabetes for clinical and non-clinical researchers. Written in the highly su
This volume aims to describe a complementary range of molecular, cell biological, andin vivo protocols used to investigate the structure–function of nuclear receptors, together with experimental appro
This volume presents detailed laboratory protocols for in vitro synthesis of mRNA with favorable properties, its introduction into cells by a variety of techniques, and the measurement of physiologica
This volume encompasses all major methodologies to interrogate endocannabinoid systems (ECS) and endocannabinoids (eCBs) signaling. With increasing interest towards the manifold activities of eCBs, th
This volume covers a range of methods used in plant cytogenetics, beginning with basic analysis of chromosomes and visualizing gene locations, to manipulating and dissecting chromosomes, and then focu
This volume includes a series of protocols focused on mitotic spindle assembly and function. The methods covered in this book feature a broad range of techniques from basic microscopy to the study of
This detailed volume explores in silico methods for pharmaceutical toxicity by combining the theoretical advanced research with the practical application of the tools. Beginning with a section coverin
This volume brings together the most widely used and important protocols currently being employed in researching and understanding bacterial cell wall homeostasis. Chapters inBacterial Cell Wall Homeo
This volume provides a wide range of protocols used in studying the nuclear envelope, with special attention to the experimental adjustments that may be required to successfully investigate this compl
Presenting state-of-the-art protocols to study gap junctions, this detailed book first focuses on the use of methods and tools to investigate the different aspects of connexin expression and gap junct
This volume aims to outline the current status of the MSC field in regenerative medicine and to propose clear and reproducible protocols to better define the identity, function and use of these cells
In addition to updating important core techniques this third edition presents new chapters on assessing leukocyte involvement in angiogenesis, lymphatic cell and pericyte isolation techniques, spheroi
This volume is a collection of research methods, techniques, and approaches to investigate the molecular biology of West Nile Virus (WNV). Chapters in the book cover many facets of WNV, such as propag
This volume contains a collection of research Natural Killer Cell methodologies relevant for both basic and translational research. These methodologies present new developments in the natural killer (
With genetic engineering, systems explored in this book now exist allowing for the simple, efficient, and near universally precise genetic manipulation directly in any organism, including the mouse. H
This third edition volume expands on the previous editions both by presenting more detailed protocols for the techniques described in the first and second editions ofHigh Throughput Screening: Methods
This volume provides a sound basis for the molecular investigation of NLR function in health and disease. Chapters focus on of innate immune receptors, “atypical” inflammasomes, biochemical and novel
This volume provides a collection of protocols and approaches for the creation of novel ligand binding proteins, compiled and described by many of today's leaders in the field of protein engineering.
This volume provides different methodologies for all classes of histone deacetylases, which includes detailed procedures on Class I and II histone deacetylase inhibitors, SIRT inhibitors, and bromodom
