Methods

This collection explores up-to-date descriptions of known G protein-coupled receptor kinase (GRK)-dependent mechanisms, both associated with G protein-coupled receptor (GPCR) functions and the recepto

Marking the 30th anniversary of theEuropean Conference on Modelling and Simulation (ECMS), this inspirationaltext/reference reviews significant advances in the field of modelling andsimulation, as wel

This detailed volume examines computer-aided drug discovery (CADD), a crucial component of modern drug discovery programs that is widely utilized to identity and optimize bioactive compounds for the d

This practical volume examines a number of topics that explore the current status of immunotherapy and diagnostic markers for neurodegenerative disorders. With a focus on Alzheimer’s disease, the firs

This detailed volume provides a single, valuable reference source for methods that definitively identify and accurately quantify apoptosis. The book begins with common methods utilized to detect and q

This text offers state of the art contributions written by world renown experts which provide an extensive background on specific classes of antibiotics and summarize our understanding as to how these

This book investigates the possible contributions of the field of Action Research today to overcome the undemocratic trends and the democratic deficits evident in modern capitalist societies, placing

“Distributed Simulation: Model Driven Engineering Approach” presents a unique frame of reference in presenting the principles, concepts, and development processes of Distributed Simulation (DS) from t

Quantitative research in social science research is changing rapidly. Researchers have vast and complex arrays of data with which to work: we have incredible tools to sift through the data and recognize patterns in that data; there are now many sophisticated models that we can use to make sense of those patterns; and we have extremely powerful computational systems that help us accomplish these tasks quickly. This book focuses on some of the extraordinary work being conducted in computational social science - in academia, government, and the private sector - while highlighting current trends, challenges, and new directions. Thus, Computational Social Science showcases the innovative methodological tools being developed and applied by leading researchers in this new field. The book shows how academics and the private sector are using many of these tools to solve problems in social science and public policy.

Quantitative research in social science research is changing rapidly. Researchers have vast and complex arrays of data with which to work: we have incredible tools to sift through the data and recognize patterns in that data; there are now many sophisticated models that we can use to make sense of those patterns; and we have extremely powerful computational systems that help us accomplish these tasks quickly. This book focuses on some of the extraordinary work being conducted in computational social science - in academia, government, and the private sector - while highlighting current trends, challenges, and new directions. Thus, Computational Social Science showcases the innovative methodological tools being developed and applied by leading researchers in this new field. The book shows how academics and the private sector are using many of these tools to solve problems in social science and public policy.

Interviewing is one of the most common techniques used to conduct qualitative research in the social sciences and humanities. As a result of globalization, researchers increasingly conduct interviews

This detailed volume aims to introduce nanomaterials as a new therapeutic regimen in treating human diseases. Divided into four sections, it explores inorganic nanomaterials, organic nanomaterials, ph

"Many theories in the social sciences predict spatial dependence or the similarity of behaviors at neighboring locations. Spatial Analysis for the Social Sciences demonstrates how researchers can diag

Contemporary society encounters profound economical, socio-ecological and political crises challenging the democratic foundation of our societies. This book addresses the potentials and challenges for

This volume contains selected papers in three closely related areas: mathematical modeling in mechanics, numerical analysis, and optimization methods. The papers are based upon talks presented on the

This thorough volume aims to provide pharmaceutical engineers with an introduction to the current state of the art in modeling and simulation of pharmaceutical processes and to summarize a number of p

This accessible text presents a detailed introduction to the use of a wide range of software tools and modeling environments for use in the biosciences, as well as the fundamental mathematical backgro

Concepts have always been foundational to the social science enterprise. This book is a guide to working with them. Against the positivist project of concept "reconstruction"—the for

Evolutionary algorithms and metaheuristics play an increasing key role in the optimum design in many applied sciences and engineering fields. This book focus on civil and structural engineering and co

Geophysical Inverse Theory and Applications, Second Edition, brings together fundamental results developed by the Russian mathematical school in regularization theory and combines them with the relate

Electromagnetic Sounding of the Earth's Interior 2nd edition provides a comprehensive up-to-date collection of contributions, covering methodological, computational and practical aspects of Electromag

Active Control of Aircraft Cabin Noise provides a bridge to fill the gap between robust control theory and practical applications of active noise control systems in aircraft cabin. Both the possibilit

There are numerous resources available on modeling and simulation, yet each typically only focuses on a narrow slice of this broad discipline. However, systems engineers need to understand the breadth

Molecular Histopathology and Tissue Biomarkers in Drug and Diagnostic Development gathers diverse experts to present state of the art guidance and application of histopathology in drug development set

This edited collection provides an introduction to the emerging interdisciplinary field of cultural mapping, offering a range of perspectives that are international in scope. Cultural mapping is a mod

Web Survey Methodology guides the reader through the past fifteen years of research in web survey methodology. It both provides practical guidance on the latest techniques for collecting valid and rel

Web Survey Methodology guides the reader through the past fifteen years of research in web survey methodology. It both provides practical guidance on the latest techniques for collecting valid and rel

This comprehensive text presents cutting-edge advances in the theory and methodology of modeling and simulation (M&S), and reveals how this work has been influenced by the fundamental contribu

This volume explores label-free biosensors, advantageous in part because this technology bypasses the need of labels, reporters, and cell engineering, all of which are common to labeled techniques but

This edited collection examines the difficulties, dilemmas and complexities of researching "hard-to-reach" groups and those who remain socially excluded and marginalized in society. Chapters examine p

This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers computational prediction RNA structure a

"Politics: The Key Concepts is an up-to-date and broad-ranging introduction to the terms that lie at the heart of political discourse. Entries are drawn from areas such as political theory, internatio

This new volume of Methods in Cell Biology looks at methods for analyzing of biophysical methods in cell biology. Chapters cover such topics as AFM, traction force microscopy, digital holographic micr

In this second edition of Counterfactuals and Causal Inference, completely revised and expanded, the essential features of the counterfactual approach to observational data analysis are presented with examples from the social, demographic, and health sciences. Alternative estimation techniques are first introduced using both the potential outcome model and causal graphs; after which, conditioning techniques, such as matching and regression, are presented from a potential outcomes perspective. For research scenarios in which important determinants of causal exposure are unobserved, alternative techniques, such as instrumental variable estimators, longitudinal methods, and estimation via causal mechanisms, are then presented. The importance of causal effect heterogeneity is stressed throughout the book, and the need for deep causal explanation via mechanisms is discussed.

In this second edition of Counterfactuals and Causal Inference, completely revised and expanded, the essential features of the counterfactual approach to observational data analysis are presented with examples from the social, demographic, and health sciences. Alternative estimation techniques are first introduced using both the potential outcome model and causal graphs; after which, conditioning techniques, such as matching and regression, are presented from a potential outcomes perspective. For research scenarios in which important determinants of causal exposure are unobserved, alternative techniques, such as instrumental variable estimators, longitudinal methods, and estimation via causal mechanisms, are then presented. The importance of causal effect heterogeneity is stressed throughout the book, and the need for deep causal explanation via mechanisms is discussed.

Far more than a mere introduction to the topic, this guide to inter- and multi-modal transportation systems analysis, modeling, and simulation extends to advanced mathematical principles and includes

"Time-series, or longitudinal, data are ubiquitous in the social sciences. Unfortunately, analysts often treat the time-series properties of their data as a nuisance rather than a substantively meanin