Thermodynamics Of Pharmaceutical Systems: An Introduction To Theory And Applications, Second Edition
商品資訊
ISBN13:9780470425121
出版社:John Wiley & Sons Inc
作者:Connors
出版日:2009/12/28
裝訂/頁數:精裝/384頁
定價
:NT$ 7317 元優惠價
:
90 折 6585 元
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
商品簡介
作者簡介
目次
商品簡介
Designed for pharmacy students
Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems.
Students and practitioners involved in drug discovery, drug delivery, and drug action will benefit from Connors' and Mecozzi's authoritative treatment of the fundamentals of thermodynamics as well as their attention to drug molecules and experimental considerations. They will appreciate, as well, the significant revisions to the Second Edition. Expanding the book's scope and usefulness, the new edition:
*
Explores in greater depth topics most relevant to the pharmacist such as drug discovery and drug delivery, supramolecular chemistry, molecular recognition, and nanotechnologies
*
Moves the popular review of mathematics, formerly an appendix, to the front of the book
*
Adds new textual material and figures in several places, most notably in the chapter treating noncovalent chemical interactions
*
Two new appendices provide ancillary material that expands on certain matters bordering the subject of classical thermodynamics
Thermodynamics need not be a mystery nor confined to the realm of mathematical theory. Thermodynamics of Pharmaceutical Systems, Second Edition demystifies for students the profound thermodynamic applications in the laboratory while also serving as a handy resource for practicing researchers.
* Provides more in-depth discussions on drug discovery and drug delivery, supramolecular chemistry, molecular recognition, and nanotechnologies
* Moves the appendix of the 1st edition to the front of the book (Chapter 0), which reviews pertinent math for greater convenience to the student
* Adds new textual material and figures in several places, most notably in Chapter 14, the chapter treating noncovalent chemical interactions; it is this chapter that most clearly distinguishes the content of this book from that of other thermodynamic texts.
* Adds two new appendices providing ancillary material that expands certain matters bordering the subject of classical thermodynamics
* Includes additional end of chapter problems for students
* Includes a solutions manual for professors for end of chapter problems
* The only textbook of its kind designed for students in the College of Pharmacy
*
Meets the needs of the contemporary curriculum designed at schools of pharmacy today and offers flexibility via the modular approach
Now updated for its Second Edition, Thermodynamics of Pharmaceutical Systems provides pharmacy students with a much-needed introduction to the mathematical intricacies of thermodynamics in relation to practical laboratory applications. Designed to meet the needs of the contemporary curriculum in pharmacy schools, the text makes these connections clear, emphasizing specific applications to pharmaceutical systems including dosage forms and newer drug delivery systems.
Students and practitioners involved in drug discovery, drug delivery, and drug action will benefit from Connors' and Mecozzi's authoritative treatment of the fundamentals of thermodynamics as well as their attention to drug molecules and experimental considerations. They will appreciate, as well, the significant revisions to the Second Edition. Expanding the book's scope and usefulness, the new edition:
*
Explores in greater depth topics most relevant to the pharmacist such as drug discovery and drug delivery, supramolecular chemistry, molecular recognition, and nanotechnologies
*
Moves the popular review of mathematics, formerly an appendix, to the front of the book
*
Adds new textual material and figures in several places, most notably in the chapter treating noncovalent chemical interactions
*
Two new appendices provide ancillary material that expands on certain matters bordering the subject of classical thermodynamics
Thermodynamics need not be a mystery nor confined to the realm of mathematical theory. Thermodynamics of Pharmaceutical Systems, Second Edition demystifies for students the profound thermodynamic applications in the laboratory while also serving as a handy resource for practicing researchers.
* Provides more in-depth discussions on drug discovery and drug delivery, supramolecular chemistry, molecular recognition, and nanotechnologies
* Moves the appendix of the 1st edition to the front of the book (Chapter 0), which reviews pertinent math for greater convenience to the student
* Adds new textual material and figures in several places, most notably in Chapter 14, the chapter treating noncovalent chemical interactions; it is this chapter that most clearly distinguishes the content of this book from that of other thermodynamic texts.
* Adds two new appendices providing ancillary material that expands certain matters bordering the subject of classical thermodynamics
* Includes additional end of chapter problems for students
* Includes a solutions manual for professors for end of chapter problems
* The only textbook of its kind designed for students in the College of Pharmacy
*
Meets the needs of the contemporary curriculum designed at schools of pharmacy today and offers flexibility via the modular approach
作者簡介
Kenneth A. Connors is Professor Emeritus in the School of Pharmacy at the University of Wisconsin at Madison. His research interests include organic analytical reactions, their catalysis, mechanisms, and applications, kinetic methods for the analysis of mixtures and the chemistry of molecular complexes.
Sandro Mecozzi received his PhD in 1996 from the California Institute of Technology, and joined the faculty of the Division of Pharmaceutical Sciences at the School of Pharmacy, University of Wisconsin-Madison, in 1999. He currently holds joint appointments in the departments of pharmacy and chemistry. His research interests include the areas of RNA recognition, fluorous self-assembly, and the development of novel drug delivery systems.
Sandro Mecozzi received his PhD in 1996 from the California Institute of Technology, and joined the faculty of the Division of Pharmaceutical Sciences at the School of Pharmacy, University of Wisconsin-Madison, in 1999. He currently holds joint appointments in the departments of pharmacy and chemistry. His research interests include the areas of RNA recognition, fluorous self-assembly, and the development of novel drug delivery systems.
目次
PREFACE.
PREFACE TO THE FIRST EDITION.
0. Review of Mathematics.
0.1. Introduction.
0.2. Dimensions and Units.
0.3. Logarithms and Exponents.
0.4. Algebraic and Graphical Analysis.
0.5. Dealing with Change.
0.6. Statistical Treatment of Data.
Problems.
I BASIC THERMODYNAMICS.
1. Energy and the First Law of Thermodynamics.
1.1. Fundamental Concepts.
1.2. The First Law of Thermodynamics.
1.3. The Enthalpy.
Problems.
2. The Entropy Concept.
2.1. The Entropy Defined.
2.2. The Second Law of Thermodynamics.
2.3. Applications of the Entropy Concept.
Problems.
3. The Free Energy.
3.1. Properties of the Free Energy.
3.2. The Chemical Potential.
Problems.
4. Equilibrium.
4.1. Conditions for Equilibrium.
4.2. Physical Processes.
4.3. Chemical Equilibrium.
Problems.
II THERMODYNAMICS OF PHYSICAL PROCESSES.
5. Introduction to Physical Processes.
5.1. Scope.
5.2. Concentration Scales.
5.3. Standard States.
Problems.
6. Phase Transformations.
6.1. Pure Substances.
6.2. Multicomponent Systems.
Problems.
7. Solutions of Nonelectrolytes.
7.1. Ideal Solutions.
7.2. Nonideal Solutions.
7.3. Partitioning Between Liquid Phases.
Problems.
8. Solutions of Electrolytes.
8.1. Coulombic Interaction and Ionic Dissociation.
8.2. Mean Ionic Activity and Activity Coefficient.
8.3. The Debye–Hückel Theory.
Problems.
9. Colligative Properties.
9.1. Boiling Point Elevation.
9.2. Freezing Point Depression.
9.3. Osmotic Pressure.
9.4. Isotonicity Calculations.
Problems.
10. Solubility.
10.1. Solubility as an Equilibrium Constant.
10.2. The Ideal Solubility.
10.3. Temperature Dependence of the Solubility.
10.4. Solubility of Slightly Soluble Salts.
10.5. Solubilities of Nonelectrolytes: Further Issues.
Problems.
11. Surfaces and Interfaces.
11.1. Thermodynamic Properties.
11.2. Adsorption.
Problems.
III THERMODYNAMICS OF CHEMICAL PROCESSES.
12. Acid–Base Equilibria.
12.1. Acid–Base Theory.
12.2. pH Dependence of Acid–Base Equilibria.
12.3. Calculation of Solution pH.
12.4. Acid–Base Titrations.
12.5. Aqueous Solubility of Weak Acids and Bases.
12.6. Nonaqueous Acid–Base Behavior.
12.7. Acid–Base Structure and Strength.
Problems.
13. Electrical Work.
13.1. Introduction.
13.2. Oxidation–Reduction Reactions.
13.3. Electrochemical Cells.
13.4. pH Measurement.
13.5. Ion-Selective Membrane Electrodes.
Problems.
14. Noncovalent Binding Equilibria.
14.1. Introduction.
14.2. The Noncovalent Interactions.
14.3. Binding Models.
14.4. Measurement of Binding Constants.
14.5. Applications.
Problems.
APPENDIXES.
Appendix A Physical Constants.
Appendix B Kinetic Theory of Gases.
Appendix C Extrathermodynamic Relationships.
ANSWERS TO PROBLEMS.
BIBLIOGRAPHY.
INDEX.
PREFACE TO THE FIRST EDITION.
0. Review of Mathematics.
0.1. Introduction.
0.2. Dimensions and Units.
0.3. Logarithms and Exponents.
0.4. Algebraic and Graphical Analysis.
0.5. Dealing with Change.
0.6. Statistical Treatment of Data.
Problems.
I BASIC THERMODYNAMICS.
1. Energy and the First Law of Thermodynamics.
1.1. Fundamental Concepts.
1.2. The First Law of Thermodynamics.
1.3. The Enthalpy.
Problems.
2. The Entropy Concept.
2.1. The Entropy Defined.
2.2. The Second Law of Thermodynamics.
2.3. Applications of the Entropy Concept.
Problems.
3. The Free Energy.
3.1. Properties of the Free Energy.
3.2. The Chemical Potential.
Problems.
4. Equilibrium.
4.1. Conditions for Equilibrium.
4.2. Physical Processes.
4.3. Chemical Equilibrium.
Problems.
II THERMODYNAMICS OF PHYSICAL PROCESSES.
5. Introduction to Physical Processes.
5.1. Scope.
5.2. Concentration Scales.
5.3. Standard States.
Problems.
6. Phase Transformations.
6.1. Pure Substances.
6.2. Multicomponent Systems.
Problems.
7. Solutions of Nonelectrolytes.
7.1. Ideal Solutions.
7.2. Nonideal Solutions.
7.3. Partitioning Between Liquid Phases.
Problems.
8. Solutions of Electrolytes.
8.1. Coulombic Interaction and Ionic Dissociation.
8.2. Mean Ionic Activity and Activity Coefficient.
8.3. The Debye–Hückel Theory.
Problems.
9. Colligative Properties.
9.1. Boiling Point Elevation.
9.2. Freezing Point Depression.
9.3. Osmotic Pressure.
9.4. Isotonicity Calculations.
Problems.
10. Solubility.
10.1. Solubility as an Equilibrium Constant.
10.2. The Ideal Solubility.
10.3. Temperature Dependence of the Solubility.
10.4. Solubility of Slightly Soluble Salts.
10.5. Solubilities of Nonelectrolytes: Further Issues.
Problems.
11. Surfaces and Interfaces.
11.1. Thermodynamic Properties.
11.2. Adsorption.
Problems.
III THERMODYNAMICS OF CHEMICAL PROCESSES.
12. Acid–Base Equilibria.
12.1. Acid–Base Theory.
12.2. pH Dependence of Acid–Base Equilibria.
12.3. Calculation of Solution pH.
12.4. Acid–Base Titrations.
12.5. Aqueous Solubility of Weak Acids and Bases.
12.6. Nonaqueous Acid–Base Behavior.
12.7. Acid–Base Structure and Strength.
Problems.
13. Electrical Work.
13.1. Introduction.
13.2. Oxidation–Reduction Reactions.
13.3. Electrochemical Cells.
13.4. pH Measurement.
13.5. Ion-Selective Membrane Electrodes.
Problems.
14. Noncovalent Binding Equilibria.
14.1. Introduction.
14.2. The Noncovalent Interactions.
14.3. Binding Models.
14.4. Measurement of Binding Constants.
14.5. Applications.
Problems.
APPENDIXES.
Appendix A Physical Constants.
Appendix B Kinetic Theory of Gases.
Appendix C Extrathermodynamic Relationships.
ANSWERS TO PROBLEMS.
BIBLIOGRAPHY.
INDEX.
主題書展
更多
主題書展
更多書展購物須知
外文書商品之書封,為出版社提供之樣本。實際出貨商品,以出版社所提供之現有版本為主。部份書籍,因出版社供應狀況特殊,匯率將依實際狀況做調整。
無庫存之商品,在您完成訂單程序之後,將以空運的方式為你下單調貨。為了縮短等待的時間,建議您將外文書與其他商品分開下單,以獲得最快的取貨速度,平均調貨時間為1~2個月。
為了保護您的權益,「三民網路書店」提供會員七日商品鑑賞期(收到商品為起始日)。
若要辦理退貨,請在商品鑑賞期內寄回,且商品必須是全新狀態與完整包裝(商品、附件、發票、隨貨贈品等)否則恕不接受退貨。

