Clarke's Analytical Forensic Toxicology

Negrusz (forensic sciences, U. of Illinois) and Cooper (forensic medicine and science, U. of Glasgow, UK) offer graduate students and teachers of forensic science, toxicology, clinical pharmacology, and analytical chemistry, as well as laboratory technicians, a textbook on analytical forensic toxicology. The 22 chapters indicate the drugs and poisons most likely to be encountered in forensic toxicology, and focus on collection, extraction, and analysis. Toxicologists, forensic medicine specialists, and others from Europe, Australia, and North America discuss pharmacokinetics and metabolism; drugs of abuse; other substances encountered in clinical and forensic toxicology, such as pesticides and natural toxins; workplace drug testing; alternative specimens; postmortem toxicology; clinical toxicology and therapeutic monitoring; drug abuse in sport; alcohol, drugs, and driving; forensic chemistry and solid dosage form identification; color tests and thin-layer chromatography; immunoassays; ultraviolet, visible, and fluorescence spectrophotometry; infrared spectroscopy; gas chromatography; high-performance liquid chromatography; and quality assurance and control. This edition has new and expanded material on pharmacogenomics, in-utero exposure to drugs of abuse, and drug-facilitated sexual assault, and new chapters on sampling, storage, and stability and techniques to extract analytes of interest from complex biological matrices. The chapter on mass spectrometry has been expanded to reflect the increasing use of liquid chromatography-mass spectrometry. New material has been incorporated from the fourth edition of Clarke's Analysis of Drugs and Poisons. Annotation c2013 Book News, Inc., Portland, OR (booknews.com)