商品簡介
The 31 chapters in this volume describe the use of nuclear magnetic resonance (NMR) in the pharmaceutical sciences. Those working in the field at American and European universities and companies discuss theory and experimental methods, including fluorine NMR spectroscopy, quantitative NMR spectroscopy, high-throughput NMR, and multivariate data analysis methods, then aspects related to the role of NMR in drug discovery and development, such as target identification and validation, NMR studies of inborn errors of metabolism, fragment-based drug design, hit discovery from natural products, structure determination of leads and candidates, mixture analysis, conformation and stereochemical analysis of drug molecules, drug efficacy and safety evaluation, preclinical drug metabolism studies, the characterization of pharmaceutical compounds, structure-based drug design, metabolic phenotyping, intellectual property protection, the analysis of counterfeit medicines and adulterated dietary supplements, regulatory control, and pharmaceutical manufacturing. Annotation c2016 Ringgold, Inc., Portland, OR (protoview.com)
作者簡介
Editors
Jeremy R. Everett, University of Greenwich, Kent, UK
Robin K. Harris, University of Durham, Durham, UK
John C. Lindon, Imperial College London, UK
Ian D. Wilson, Imperial College London, UK
