Bioanalysis of Pharmaceuticalsis thefirst student textbook on the separation science and mass spectrometry of pharmaceuticals present in biological fluids, with an educational presentation of the principles, concepts, and applications. It discusses the chemical structures and properties of low- and high-molecular drug substances; the different types of biological samples and fluids that are used; how to prepare the samples by extraction, and how to perform the appropriate analytical measurements by chromatographic and mass spectrometric methods.
The book includes multiple examples to illustrate the theory and applications, with many practical aspects including calculations, thus helping the student to learn how to convert the data recorded by instruments into the real concentration of the drug substances within the biological sample.
Bioanalysis of Pharmaceuticals:
Steen Honore Hansen
Department of Pharmacy, Faculty of Health and Medical Sciences, Copenhagen University, Denmark
Stig Pedersen-Bjergaard
School of Pharmacy, University of Oslo, Norway, and Department of Pharmacy, Faculty of Health and Medical Sciences, Copenhagen University, Denmark
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