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This book focuses on strategies and tactics for the efficient synthesis of natural products. The state-of-the-art of the topic covered include economic and protecting-group-free synthesis, computer-aided total synthesis, organometallics-based catalytic (asymmetric) synthesis, biomimetic and bio-inspired synthesis, as well as different classes of organic reactions. Other chapters address chemical building blocks, technologies of chemical and biological space, and synthetic biology. A key part of the coverage is the illustration of how these practices and strategies influence drug discovery – about half the drugs in clinical use stem from natural products – and chemical biology.
作者簡介
Pei-Qiang Huang, PhD, is Professor of Chemistry and Dean of the College of Chemistry and Chemical Engineering at Xiamen University.
Zhu-Jun Yao, PhD, is Cyrus Tang Chair Professor and University Distinguished Professor at Nanjing University.
Richard Hsung, PhD, is a professor of Pharmaceutical Sciences and Chemistry at the Pharmacy Experience University of Wisconsin.
Zhu-Jun Yao, PhD, is Cyrus Tang Chair Professor and University Distinguished Professor at Nanjing University.
Richard Hsung, PhD, is a professor of Pharmaceutical Sciences and Chemistry at the Pharmacy Experience University of Wisconsin.
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