Oral Formulation Roadmap From Early Drug Discovery To Development

This book describes and explains the key factors that help determine the types of formulation needed throughout the stages of drug discovery. Detailing formulation approaches by stage of discovery to early development, the book helps scientists across the different disciplines involved in drug discovery. The covered topics include regulatory filing, drug metabolism and properties, the biopharmaceutics classification system (BCS), screening approaches, and the role of outsourcing organizations to improve drug development timelines. Chapters discuss the practical challenges and solutions, providing content to guide pharmaceutical scientists in the proper use of resources to generate drug leads and make quick decisions. The enhanced ebook version uses short video clips of formulation preparation.

Elizabeth Kwong, PhD, retired from Merck & Co., Inc. in 2011, after 23 years of service. She then established her own company, Kwong Eureka Solutions, as a consultant for small start-up companies and specialty drug products. Dr. Kwong is on the Board of Directors for the Canadian Society of Pharmaceutical Scientists and is also an adjunct professor in the Department of Pharmaceutics at the University of Montreal and Department of Chemistry at Concordia University. More recently, Dr. Kwong also co-founded a start-up company, Giiant Pharma, working on delivering a colon specific PDEIV Inhibitor prodrug for the treatment of Ulcerative Colitis.