★ 普立茲獎得主震撼巨作,重新定義「人類是誰」
★ 從DNA到基因編輯,揭開生命最深層的祕密
★ 科學 × 家族故事 × 人性倫理,最動人的科普經典
基因,是人類歷史上最強大、也最危險的概念之一。
從孟德爾的豌豆實驗,到DNA的發現,再到改寫生命的CRISPR基因編輯技術,這不只是一段科學進展史,更是一場關於「我們是誰」的深刻追問。悉達多.穆克吉以醫師與研究者的視角,串聯百年來的科學突破,同時融入自身家族面對精神疾病的故事,讓冰冷的基因研究,轉化為關於命運、遺傳與選擇的動人敘事。
當我們逐漸掌握改寫生命的能力,也同時站在倫理與未來的十字路口——我們該如何使用這份力量?
這是一部兼具科學深度與文學美感的經典之作,帶領讀者理解基因如何塑造人類,也讓我們思考,未來將由誰來定義人類。
Selected as a Book of the Year by The New York Times, The Economist, Independent, Observer and Mail on Sunday
THE NEW YORK TIMES NUMBER ONE BESTSELLER
SHORTLISTED FOR THE WELLCOME BOOK PRIZE 2017
‘Dramatic and precise… [A] thrilling and comprehensive account of what seems certain to be the most radical, controversial and, to borrow from the subtitle, intimate science of our time… He is a natural storyteller… A page-turner… Read this book and steel yourself for what comes next’
Bryan Appleyard, Sunday Times
The Gene is the story of one of the most powerful and dangerous ideas in our history, from bestselling, prize-winning author Siddhartha Mukherjee.
Spanning the globe and several centuries, The Gene is the story of the quest to decipher the master-code that makes and defines humans, that governs our form and function.
This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.
The story of the gene begins in an obscure Augustinian abbey in Moravia in 1856 where a monk stumbles on the idea of a ‘unit of heredity’. It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.
Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.
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