Gene Synthesis

The de novo fabrication of custom DNA molecules is a transformative technology that significantly affects the biotechnology industry. Basic genetic engineering techniques for manipulating DNA in vitro

Current knowledge of the genetic, epigenetic, behavioural and symbolic systems of inheritance requires a revision and extension of the mid-twentieth-century, gene-based, 'Modern Synthesis' version of Darwinian evolutionary theory. We present the case for this by first outlining the history that led to the neo-Darwinian view of evolution. In the second section we describe and compare different types of inheritance, and in the third discuss the implications of a broad view of heredity for various aspects of evolutionary theory. We end with an examination of the philosophical and conceptual ramifications of evolutionary thinking that incorporates multiple inheritance systems.

This book focuses on the regulation of transcription and translation in Archaea and arising insights into the evolution of RNA processing pathways. From synthesis to degradation and the implications o

After a short introduction and a brief review of the relation between carbon nanotubes, graphite and other forms of carbon, the synthesis techniques and growth mechanisms for carbon nanotubes are desc

This book provides a premier resource on understanding the ribosome's essential nature and how it interacts with other proteins and nucleic acids to control protein synthesis. As one of the central fo

No longer simple line drawings on a page, molecular structures can now be viewed in full-figured glory, often in color and even with interactive possibilities. Anatomy of Gene Regulation is the first book to present the parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and their companion proteins are revealed in full-color, three-dimensional form. Beginning with a general introduction to three-dimensional structures, the book looks at the organization of the genome, the structure of DNA, DNA replication and transcription, splicing, protein synthesis, and ultimate protein death. Throughout, the text employs a discussion of genetics and structural mechanics. The concise and unique synthesis of information will offer insight into gene regulation, and into the development of methods to interfere with regulation at diseased states. This textbook and its accompanying web site are appropriate for both undergraduate and graduate students

No longer simple line drawings on a page, molecular structures can now be viewed in full-figured glory, often in color and even with interactive possibilities. Anatomy of Gene Regulation is the first book to present the parts and processes of gene regulation at the three-dimensional level. Vivid structures of nucleic acids and their companion proteins are revealed in full-color, three-dimensional form. Beginning with a general introduction to three-dimensional structures, the book looks at the organization of the genome, the structure of DNA, DNA replication and transcription, splicing, protein synthesis, and ultimate protein death. Throughout, the text employs a discussion of genetics and structural mechanics. The concise and unique synthesis of information will offer insight into gene regulation, and into the development of methods to interfere with regulation at diseased states. This textbook and its accompanying web site are appropriate for both undergraduate and graduate students

Building on the success of its predecessor, Carbon Nanotubes: Synthesis, Structure, Properties and Applications, this second volume focuses on those areas that have grown rapidly in the past few years

Building on the success of Carbon Nanotubes: Synthesis, Structure, Properties and Applications, this second volume focuses on rapid growth areas in nanotube research. Among the new topics covered are

In Harm's Way: A History of the American Military Experience offers a fast-paced, highly readable synthesis of modern scholarship on every era of the nation's experience in war. Authors Gene Allen Smi

Artificial riboswitches and other ligand-responsive gene regulators make it possible to switch protein synthesis ON or OFF with arbitrary ligand molecules. Artificial Riboswitches: Methods and Protoco

Neuroscientists investigate the mechanisms of spatial memory. Molecular biologists study the mechanisms of protein synthesis and the myriad mechanisms of gene regulation. Ecologists study nutrient cyc

This book covers the design and synthesis of DNA and RNA nanostructures with the aim of using them for drug deliveries, for genetic immunization, for metabolite and nucleic acid detection, gene regula

First published in 1984, this volume comprised a broad synthesis of contemporary research on sheep reproduction conducted in Australia. Australia is internationally recognized for the excellence of its research in this field, and heads the world in areas of the neuro-endocrine control of reproduction, reproductive behaviour, artificial insemination and manipulation of reproductive performance, to name just a few. The book comprises some 23 review papers and short communications, all refereed by experts in the field, covering such topics as neuro-endocrinology, sexual behaviour, testicular and ovular function, pregnancy and foetal growth, parturition, lamb survival, nutrition and genetics. Advanced methods, developed in the seventies and early eighties to control reproductive function, gene manipulation and intra-uterine insemination are also considered, together with the managerial and economic values of such developments.

During the past decade as the data on gene sequences and expression patterns rapidly accumulated, cell-free protein synthesis technology has also experienced a revolution, becoming a powerful tool for

Beginning with the basic concept of gene cloning, topics such as restriction endonucleases, chemical synthesis of oligonucleotides, cDNA synthesis, plasmids, and polymerase chain reaction have been di

In past years considerable interest has been focused on migration as an important cause of change in the genetic and demographic structure of human populations. This book synthesises the biological consequences of changes environments on the migrants and the genetic impact of immigration on the host populations. Patterns of migration, past and present and genetic, epidemological and demographic consequences are considered, forming a unique synthesis for human biologists in general. Individual chapters deal with the peopling of the continents, migration in the recent past, the effects of gene flow and rural to urban migration. In addition, a detailed analysis of the relationship between migration, adaptation and disease is presented. Advanced students and research workers in a wide variety of disciplines, including population genetics, demography, anthropology and social geography will find this book particularly valuable in relating their own special interests to other biological aspec

This work on translational control--the central idea of which is that gene expression is regulated by the efficiency of utilization of messenger RNA in specifying protein synthesis--is a successor of

Plants are able to respond and adapt to changing environmental and endogenous signals by the induction of the synthesis of specific proteins, acting to modify cellular metabolism. Environmental signals include temperature, anaerobiosis and pathogen attack amongst others, whilst endogenous signals include changes in the level of plant growth regulators. In this 1992 text, leading researchers discuss the role that inducible proteins play in cellular metabolism, and the approaches being used to delineate the molecular events leading to their synthesis. Chapters discuss molecular approaches to the study of gene expression, the identification and characterisation of trans-acting transcription factors and attempts to dissect other parts of the signal transduction pathway by the search for pathway mutants. This review volume will be of great value and interest to final year undergraduates, graduate students and researchers in the fields of plant biochemistry and molecular biology.

Here is the most complete guide available to the isolation, analysis, and synthesis of RNA. It covers everything researchers and laboratory workers need to know about the study of gene expression via

Neuroscientists investigate the mechanisms of spatial memory. Molecular biologists study the mechanisms of protein synthesis and the myriad mechanisms of gene regulation. Ecologists study nutrient cyc