The Rho GTPases were first discovered due to their homology to Ras GTPase. Approximately 30% of human cancers harbor an activating mutation to Ras, and Ras mutations promote cell growth and survival.
Featuring experimental approaches that shed light on the complexity of Ras GTPase biological functions, Ras Signaling: Methods and Protocols contains general overviews and detailed applications of bot
This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes
This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes
This second of two volumes discusses subfamily proteins which function in molecular and vesicular transport mechanisms inside the cell. In this volume the focus lies on the Rab, Ran and Arf subfamily
The Local Cardiac Renin-Angiotensin Aldosterone System, Second Edition updates new findings on the local renin-angiotensin systems (RAS) with a focus on the local RAASs of the cardiovascular system a
This book presents a detailed analytical formulation, and step-by-step design procedure for the electromagnetic (EM) design of radar absorbing structures (RAS). It discusses both the equivalent circui
The human pancreas has vital roles in the regulation of glucose homeostasis and digestion and its dysfunction leads to pancreatic disease as diabetes and pancreatitis. Recent researches have highlight
The aim of this book is to gather the most recent works that address issues related to the concept of mining complex data. The whole knowledge discovery process being involved, our goal is to provide
This book constitutes the refereed proceedings of the 18th International Conference on Computer Assisted Assessment, CAA 2015, held in Zeist, The Netherlands, in June 2015. The 15 revised full pa
This book constitutes the refereed proceedings of the International Conference on Computer Assisted Assessment, CAA 2014, held in Zeist, The Netherlands, in June/July 2014. The 16 revised full papers
Maluf, Davide Martinenghi, Stan Matwin, Natasha Noy, Werner Nutt, James Peters, Jean-Marc Petit, Vijay Raghavan, Jan Rauch, Gilbert Ritschard, Erik Rosenthal, Marie-Christine Rousset, Nahid Shahmehri,
This book constitutes the proceedings of the 20th International Symposium on Methodologies for Intelligent Systems, ISMIS 2012, held in Macau, China, in December 2012. The 42 regular papers and 11 sho
The authors present the theory of symmetric (Hermitian) matrix Riccati equations and contribute to the development of the theory of non-symmetric Riccati equations as well as to certain classes of cou
Data mining applications range from commercial to social domains, with novel applications appearing swiftly; for example, within the context of social networks. The expanding application sphere and so
This book presents a modified model reference adaptive system (MRAS) observer for sensorless vector control of a wind driven doubly fed induction generator (DFIG). A mathematical model of the DFIG as
This book constitutes the refereed proceedings of the 29th IFIP TC 11 International Information Security and Privacy Conference, SEC 2014, held in Marrakech, Morocco, in June 2014. The 27 revised full