Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

'A master class in human behavior from someone who’s lived it at the highest level.' – Steven Bartlett, author of The Diary of a CEO Simple but powerful body language skills to connect instantly with anyone and build rapport, from the international bestselling author of What Every Body is Saying, Joe Navarro. Over his twenty-five-year career as an FBI counterintelligence officer, Joe Navarro had to read people in an instant, build trust in the most reluctant of people and nurture life-long relationships. The key to achieving it was simple but powerful: body language. In Mastering Connections, Navarro draws on his unique experiences and shows readers how to apply these skills to their everyday lives. In this book, you will discover how to: Master the art of the first impressionBuild trust and rapport with someone newHandle workplace negotiationsDefuse tension and conflictBe prepared for a first dateFoster life-long relationships.

Learn to live in the moment in this magical fantasy adventure that teaches us to leave behind the mundane and delight in imagination and play! After Daddy has finished working from home for the day, his daughter takes him out on a walk that soon turns into an epic journey across enchanting landscapes. Along the way, they encounter magical creatures like trolls and pixies, yetis and giants, but Daddy doesn’t believe in any of them! Will she convince her dad to put away the distraction of his work crisis, and finally see the magic all around them? Learn to let go of the day-to-day and enjoy magical moments with our loved ones.

A funny bedtime picture book in an extra tall split-page novelty format!From award-winning picture book creator Guilherme Karsten, illustrator of Hen in the Bed.Praise for Hen in the Bed:"Charming version of the classic counting song "Ten in the Bed"" - BookTrustIt's night-time and everyone is fast asleep, until - WAAAH! - Baby Giraffe wakes up. Oh dear! As each animal wakes up the neighbour in the apartment below with their noisy snip-snapping, chattering and ROARING, soon the whole building is wide awake. Will anyone ever get any sleep. . .? Oh my! What a night!Turn the split pages to see the noisy mayhem mount up - and spot some cheeky mice joining the fun!Includes a FREE Nosy Crow Stories Aloud® audiobook! Scan the code, hear the story.

Build new cars in the factory, put speedy trains on the tracks and stick enormous planes on the runway in this exciting book. There are all sorts of vehicles to spot and talk about on every page. With over 450 stickers to add to the charmingly illustrated scenes.

Ancient Greek classic about the amazing adventures of Odysseus, in graphic novel form.Greek warrior Odysseus is desperate to make his way home to the island of Ithaca. But giants, sirens and many-headed serpents are just some of the obstacles that stand in his way. Join him on his amazing adventures in this dynamic graphic novel.

An easy-to-read introduction to world history for young children.A bright, lively introduction to world history - from the dinosaurs to the Civil Rights Movement - with simple text, amazing photographs and detailed illustrations. Provides clear explanations to questions such as "Who lived in the Forbidden City?", "Where did the Vikings come from?" and "What was the Industrial Revolution?"- Includes acomprehensive index, plusQR linksto selected websites and videos atUsborne Quicklinks.- An idealstarting pointandreference bookfor any child with questions about history.Chapters in this book include:- Dinosaur world- The first people- The first farmers- The first cities- Ancient Egypt- Celtic warriors- Ancient Greece- Ancient China- Ancient Rome- Viking raiders- African kingdoms- Living in a castle- Living in a village- Inca cities- Aztec life- Italian ideas- Exploring the world- Tudor England- Ming China- Russian rulers- Living in Japan- Living in America- Mogul India- Dutch traders- Fren

Help the baby sea animals find their way home in this fun sliding counter board book series!Meet baby turtle, baby dolphin, baby clownfish and baby whale - four adorable animals who are lost in the waves!With easy-to-use moving parts and four unique tracks to develop hand-eye coordination and concentration, babies and toddlers will enjoy taking the baby animals home in this robust board book.Includes a FREE Nosy Crow Stories Aloud® audiobook! Scan the code, hear the story.Other titles in the Let's Go Home series include:*Baby Tiger*Baby Shark*Baby T-Rex*Let's Go Home, Baby Panda

This beautifully illustrated flap book transports the reader back in time to the amazing world of the dinosaurs. From fearsome meat-eaters to giant herbivores, readers can lift the different flaps to discover the very different world these big beasts lived in. Discover the strange, feathery dinosaurs who lived in deserts, what a T.Rex had for lunch, the massive reptiles who soared in the sky and swam in the sea, before finding out why dinosaurs no longer live with us. Or do they...?

Wiska Wildflower is back! From the creator of Isadora Moon, Harriet Muncaster. Told in diary format and packed with beautiful full-colour illustrations, this is the enchanting story of Wiska Wildflower's first school expedition-to one of the most dangerous places in all of Wiskling Wood! We're going on a school trip to Wiskling Mountain! We have to read a map and make our own camp and find and cook our own food-it's a BIG deal. Wiska is excited to be paired with Citrine for the school trip, but when Citirne persuades her to join her on a secret mission to find a rare starflower, she begins to have doubts.After disaster strikes, the friends seek sanctuary in a hidden spot in Wiskling Wood. What they find there is incredible and life-changing. But will their friendship survive this dangerous adventure? Book 2 following the Children's bestseller The Diary of Wiska Wildflower: The New School.

Can two very different women put aside their differences to save the bookstore they love? The Japanese bestseller that kicked off a seven-book series – adapted for TV and 200,000 copies soldRiko Nishioka is assistant manager of the flagship Pegasus bookstore in Kichijoji. After working her way up from a part-time position, she is now, aged forty, a respected figure in the Japanese publishing industry. But she has a nemesis.Aki Kitamura, twenty-seven, has waltzed in as a full-time employee thanks to her family connections. A free spirit with a rebellious streak and a silver spoon in her mouth, she’s anything but a team player.The two are always clashing – both at work and over their personal lives. But when Riko is given notice that the store will be closing in six months’ time, they face a stark choice.Can they put their petty enmities aside to boost sales and save their livelihoods or will they go down fighting . . . each other?Translated from the Japanese by Haydn Trowell

Experience the world of fashion in a whole new way with Fashion Unfolded – an enthralling pop-up book series bringing stories of legendary brands to life in three-dimension. Fashion Unfolded is a series that renders fashion history in three dimensions—where popups reveal iconic moments, timeless designs, and lasting legacies in an engaging exploration of style and history across celebrated houses. Following on from the success of Chanel and Dior, the third title in this captivating pop-up book series delves into the history, legacy and iconic creations of the world renowned fashion brand Louis Vuitton.Each pop-up spread showcases legendary designs and celebrated pieces, from the iconic Speedy bag to the signature trunks, brought to life with intricate paper engineering and illustrations. With its hardcover design and matching slipcase, Fashion Unfolded is both a charming gift and timeless collectable for fashion enthusiasts.