Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

The first book in a laugh-out-loud early graphic novel series perfect for fans of Narwhal and Jelly! Quiet-loving Moose's life is turned upside down by free-wheeling Duck. The two will need to put their differences aside if they're ever going to be neighbors...or friends!Moose loves peace and quiet, relaxing, living alone, and spring! He can't wait for the arrival of sun, flowers, and...a new neighbor?! Duck just landed himself a new home. He loves parties, karaoke, and living with—and on—Moose's head. Moose tries everything he can to send Duck away, but he soon finds that this persistent neighbor might just be the best thing spring could bring.Filled with zany hijinks and slapstick humor, Kirk Reedstrom's Duck and Moose series showcases unlikely friendships and the power of compromise.

A runaway queen. A reluctant prince. And a quest that may destroy them both.Eight years have passed since the Battle of the Serpent. But in the icy north, Lady Nore of the Court of Teeth has reclaimed the Ice Needle Citadel. There she is using an ancient relic to create monsters of stick and snow who will do her bidding and exact her revenge.Suren, child queen of the Court of Teeth, and the one person with power over her mother, fled to the human world, where she lives feral in the woods. Lonely, and still haunted by the merciless torments she endured in the Court of Teeth, she bides her time by releasing mortals from foolish bargains. She believes herself forgotten until the storm hag Bogdana chases her through the night streets.Suren is saved by none other than Prince Oak, heir to Elfhame, to whom she was once promised in marriage and who she has resented for years. Now seventeen, Oak is charming, beautiful and manipulative. He's on a mission that will lead him into the north, and he

The clever and hilarious star of the Geisel Award winners Fox at Night and Fox the Tiger is back in another I Can Read adventure.There's only one Fox . . . except when there are two!Will Fox outfox this new fox? Or will he make a new friend?Carefully crafted using basic language, word repetition, sight words, and whimsical illustrations, Fox versus Fox is ideal for sharing with your emergent reader. The active, engaging My First I Can Read stories have appealing plots and lovable characters, encouraging children to continue their reading journey. Other Fox books include Fox Has a Problem, Fox at Night, Fox versus Winter, Fox the Tiger, Fox Is Late, Fox and the Jumping Contest, and Fox and the Bike Ride.

Form Follows Fever is the first in-depth account of the turbulent early years of settlement and growth of colonial Hong Kong across the 1840s. During this period, the island gained a terrible reputation as a diseased and deadly location. Malaria, then perceived as a mysterious vapour or miasma, intermittently carried off settlers by the hundreds. Various attempts to arrest its effects acted as a catalyst, reconfiguring both the city’s physical and political landscape, though not necessarily for the better. Caught in a frenzy to rebuild the city in the devastating aftermath, this book charts the complex interplay between a cast of figures, from military surveyors, naval doctors, Indian sepoys, and corrupt and paranoid officials to opium traders, arsonists, Chinese contractors, and sojourner architects and artists. However, Hong Kong’s ‘construction’ was not just physical but also imagined. Architecture, cartography, epidemiology, and urban infrastructure offer a critical forensic l

本書最主要的特點是資料結構和實做導向，雖然經濟計量方法有紮實的理論基礎，但是此學門的本質依然是一個以模型化實際經濟問題為核心的實證學科，因此，學習的目的不但需要瞭解資料結構，更要認識財務與經濟學的模型，本書在理論端的說明，盡可能由資料結構解說清楚，而不以矩陣代數和證明為主；所有實做程式碼，可從作者的網頁下載（https://web.ntnu.edu.tw/~tsungwu/QEWise2024.zip）。本書特色如下：一、在單一方程式中，除了以穩健統計方法專章將分量迴歸併入，也對混頻方法MIDAS做了比較深入的解說與實做說明；二、在多變量時間序列，增加了一個略有技術難度的模型：Global VAR。GVAR是一個重要的政策工具，實做上主要採用R社群的Bayesian Global VAR套件，功能完備許多，同時也納入Structural VAR/VECM，讓經濟理論更能結合計量方法；三、非線性模型部分包含：門檻模型、平滑移轉、結構變動與馬可夫轉換，這些模型有一些是在VAR架構下處理。

世界第1強AI ChatGPT Turbo 自學魔法寶典 Data Analyst +GPTs + DALL-E+ Copilot + Prompt Midjourney + Suno + D-ID + Runway + Gamma （頂級雪銅紙全彩印刷版） ★☆★☆★【用最正確觀念學習ChatGPT Turbo】★☆★☆★ ☆★☆★☆【內容最多：應用範圍最廣】☆★☆★☆ ★☆★☆★【ChatGPT引領：教育與日常的智慧融合】★☆★☆★ ☆★☆★☆【AI畫師：數位藝術的新境界】☆★☆★☆ ★☆★☆★【GPTs的藝術：從應用到設計的精妙旅程】★☆★☆★ ☆★☆★☆【旋律智慧：探索AI音樂的魔法】☆★☆★☆ ★☆★☆★【智慧簡報：AI如何改變演講之藝】★☆★☆★ ☆★☆★☆【智慧分析：數據的深度探索】☆★☆★☆ 本書將以最正確觀念引領讀者學習ChatGPT Turbo，讀者同時可以學會下列應用： ◎ChatGPT多模態的輸入與應用 ★認識AI幻覺(AI hallucinations) ☆文字、語音與文件輸入 ★工作與學習效率提升 ☆Excel到Data Analyst的數據分析 ◎AI視覺與智慧 ★上傳與分析5大類檔案 ☆認識AI智慧 ◎ChatGPT在生活的應用 ★英語翻譯機與英語學習機 ☆文藝創作 ★戀愛顧問 ◎ChatGPT在教育的應用 ★學生提高學習效率 ☆輔導學生未來應徵工作 ★老師教學增強教學效能 ◎ChatGPT在企業的應用 ★SEO關鍵字掌握 ☆行銷應用 ★企業公告與談判 ☆法律文件生成與檢視 ◎Prompt提示工程 ★專家角色扮演 ☆讓ChatGPT了解你的問題 ★讓ChatGPT了解你期望的輸出 ☆有效率的與ChatGPT聊天 ◎ChatGPT App ★ChatGPT App與iPhone捷徑 ☆Siri啟動ChatGPT ★ChatGPT App智慧聊天 ◎GPTs機器人 ★聰明應用當下最熱門的機器人程式(GPTs) ☆5個GPTs實例教你打造你的工作GPTs ◎Copilot ★Copilot多模態聊天 ☆Copilot繪圖/視覺 ★Designer ☆手機應用–Copilot App ◎Copilot側邊欄 ★網站閱讀與分析 ☆撰寫創意文件 ◎AI繪圖 ★從ChatGPT、DALL-E到Midjourney ☆聊天繪圖到風格轉換 ★邁向心靈畫

本書集結作者在漢語語文學方面的單篇論文，內容涉及校讎學、版本目錄學、聲韻學、詩律學、經學，乃至訓蒙之作，與此書血脈相連的Ancient Chinese and Early Mandarin、《詩經的歌謠形式、韻式與韻讀》等部頭較大的，先已抽出刊行。整理舊稿，極為繁瑣，得老妻雪真聯絡陳嶸、高曼玲諸同學，勉力從事，在此申謝。

In 2024 explore a magical illustrated new world for children aged 7-9 from the best-selling creator of Amelia Fang!A magical illustrated new young fiction series for children aged 7-9 from best-selling author and illustrator, Laura Ellen Anderson!Meet Marnie Midnight – a little moth with BIG dreams!Marnie Midnight is SO excited to be starting at Minibeast Academy. She adores everything about the moon and she can’t wait to learn about its magic. But Marnie soon discovers that nobody believes in moon magic anymore!Marnie is determined to get to the bottom of this moon mystery. The little moth and her minibeast friends explore far and wide in their search for the truth. But will they survive a run-in with a rebellious rat or an out-of-this-world trip with the terrifying Early Bird . . . ? One thing is for sure, Marnie is a little bug having a BIG Adventure!

地理資訊系統廣泛應用於交通運輸、都市規劃、社會科學等學科中，為學術研究與實務之必備工具，以瞭解運輸系統、土地使用與空間的關聯及互動，進而提出合理的交通與國土規劃。地理資訊系統可儲存大量空間與屬性資料並分析，亦可透過地圖視覺化闡述空間特徵，以從中推演政策意涵，提出具體建議。本書內容旨在介紹地理資訊系統於R語言的應用，強化資料分析之技術，使空間分析得以更具彈性。此外亦透過大量實務資料，闡釋分析架構與方法，提供更全面的應用說明。目前正式出版的中文相關教科書皆著重於介紹使用者介面軟體，惟使用者介面軟體較缺乏彈性，抑或功能多元的商業軟體所費不貲，故本書希冀透過免費開源軟體於地理資訊系統的應用，融合數據科學與空間分析，進而強化學術與實務研究之應用。

當一對雙胞胎無法就誰的數學更好達成一致時，他們的父親給了他們一個令人困惑的問題。只要一點線索，誰會先找到答案？我是數學明星！系列包括具有挑戰性的數學難題，以故事形式呈現。透過引人入勝的故事情節，並使用各種數學啟發式技巧，逐步描述謎題，然後逐步解決，這些技巧也是世界著名的新加坡數學課程的一部分。透過插圖和引人入勝的故事情節，孩子們將學習數學啟發法，並受到啟發，堅持理解、表現和解決有趣的數學問題！系列特點：根據新加坡數學課程的規定，學習使用數學啟發法解決數學難題每本書都包含由 Yeap Ban Har 撰寫的解決問題指南When a pair of twins cannot agree on who is better in Maths, their father sets them a baffling problem. With just a few clues, who will find the answer first?The I'm a Maths Star! series comprises challenging Maths puzzles, presented in story form. Puzzles are described and then solved, step-by-step, through an engaging storyline, and using various Maths heuristic techniques that are also taught as part of the world-renowned Singapore Maths curriculum. Through illustrations and an engaging storyline, children will learn Maths heuristics, and be inspired to persevere in understanding, representing, and solving fun and intriguing Maths problems!Series features:Learn to solve difficult Maths problems using Maths heuristics, as ident

當一對雙胞胎無法就誰的數學更好達成一致時，他們的父親給了他們一個令人困惑的問題。只要一點線索，誰會先找到答案？我是數學明星！系列包括具有挑戰性的數學難題，以故事形式呈現。透過引人入勝的故事情節，並使用各種數學啟發式技巧，逐步描述謎題，然後逐步解決，這些技巧也是世界著名的新加坡數學課程的一部分。透過插圖和引人入勝的故事情節，孩子們將學習數學啟發法，並受到啟發，堅持理解、表現和解決有趣的數學問題！系列特點：根據新加坡數學課程的規定，學習使用數學啟發法解決數學難題每本書都包含由 Yeap Ban Har 撰寫的解決問題指南When a pair of twins cannot agree on who is better in Maths, their father sets them a baffling problem. With just a few clues, who will find the answer first?The I'm a Maths Star! series comprises challenging Maths puzzles, presented in story form. Puzzles are described and then solved, step-by-step, through an engaging storyline, and using various Maths heuristic techniques that are also taught as part of the world-renowned Singapore Maths curriculum. Through illustrations and an engaging storyline, children will learn Maths heuristics, and be inspired to persevere in understanding, representing, and solving fun and intriguing Maths problems!Series features:Learn to solve difficult Maths problems using Maths heuristics, as ident

《Dollars to Doughnuts!》是專為孩子設計的理財啟蒙系列，從零用錢到刷卡觀念，輕鬆入門。當Lucy生日收到一張塑膠卡，她開心地想買一件亮晶晶的上衣，卻發現金額不夠——原來禮物卡和信用卡不一樣？透過Lucy與好友Julian的日常經歷，孩子將自然理解禮物卡與信用卡的差異、各自的優缺點，是適合初階閱讀者的理財故事入門From budgeting to spending, from credit cards to gift cards, this new early chapter book series tackles and explains big financial topics for kids, Dollars to Doughnuts! When Lucy's aunt gives her a card--the plastic kind--for her birthday, Lucy knows just the blinged-out sweatshirt to spend it on. She plunks the card down at the store, but, cringe, it comes up short! Wait, what's the difference between a gift card and a credit card? In this early chapter book designed to help kids decipher finance facts and fallacies, Lucy and her best friend, Julian, find out about the pros and cons of gift cards versus credit cards.

《Dollars to Doughnuts!》系列以親切故事幫助孩子理解重要的金錢觀念。本集中，Julian和Lucy在料理課釀成「麵糊災難」，為了修補廚房，他們打算辦一場烘焙義賣會。但他們很快遇上難題——要怎麼擬定預算？而且還得守住？From budgeting to spending, to credit cards and gift cards, this new early chapter book series tackles and explains big financial topics for kids, Dollars to Doughnuts! After a batter disaster, Julian and Lucy's cooking class needs a kitchen cleanup, including a new paint job. Luckily, they have a plan to make things right--they'll simply throw the bake sale of the century! But their sweet dreams dissolve like sugar when faced with the b-word: Budget. What is a budget and how are they ever supposed to stay within it? In this early chapter book designed to help kids decipher finance facts and fallacies, Lucy and Julian discover the ins and outs of budgeting.

When the Yellow River Floods explores the relationship between environmental degradation, hydraulic engineering, and nation-building in the context of Liu E’s The Travels of Lao Can. This book contributes to the field by providing a unique perspective on modern Chinese literary history that goes beyond conventional narratives that focus solely on political and cultural factors. The main areas covered include the role of water management in literary nation-building and the connections between the novel’s various themes, such as river engineering, medical and political discourses, national sentiment, and landscape description. The book is targeted toward scholars and students of Chinese literature, history, and environmental studies, as well as those interested in the intersections between literature, nation-building, and environmental challenges. By offering a comprehensive and material-based analysis of The Travels of Lao Can, this book broadens the understanding of nation-building in

A beautifully illustrated series that grows with your baby.Baby's First Stories presents a unique blend of read-aloud stories and high-contrast visuals, featuring an adorable elephant, panda, whale and bunny. Each story has been created in consultation with Early Years Expert Lizzie Noble, to perfectly suit your baby's needs at every stage in their first year.9-12 months prompts older babies to interact with the book, tickling panda's tummy and looking for details in the artwork to reflect your baby's ability to spot fine details and respond to basic questions. Jane Foster's black-and-white artwork features bold pops of blue, red and yellow, including hidden details - reflecting your baby's sharpening eyesight.Neither too long, nor too short, each story will easily fit into baby's day, to make reading together a regular activity. Beautifully illustrated by award-winning textile designer Jane Foster, and written by picture book rising-star, Lily Murray.

Join Simon and Chester in their fourth adventure as they navigate friendship, jealousy and new friends. A hilarious early graphic novel series for fans of The Bad Guys and Dog Man.Welcome to the world of Simon and Chester, ghost and boy duo extraordinaire.Chester lives with his Grandma, his cat Mr. Pickles and Simon the ghost. Simon and Chester are best friends. Their attic is the location for some of the best activities known to humankind: making up songs about passersby, acting out scenes from Simon's exciting Dr. Darington novels and creating the incredible Treat-A-Matic snack dispenser.But Chester has also befriended a non-ghost named Amie, and she is coming over to work on their science fair project. Amie has a surprising idea for this project, and Simon and Chester's friendship will be put to the test as a result. Will Simon behave? Will Amie come between the two friends? Will an invisible Simon make fart noises that Chester has to explain? All will be revealed . . .Series Overvi

榮獲ANTHEM大獎，入選《金融時報》2024年度最佳好書——《演算法》揭露AI正在悄悄主宰我們的工作與生活。記者Hilke Schellmann深入追蹤演算法如何影響求職、監控員工、甚至預測心理健康。她揭示AI背後的偏見與錯誤，並呼籲人類應奪回對未來的主導權。在這個AI重塑世界的時代，本書是一道警鐘，也是一線希望。ANTHEM AWARD WINNER • NAMED A FINANCIAL TIMES BEST BOOK OF THE YEAR 2024AI is on the brink of dominating our lives, threating our privacy and human future—if we don’t take action now. In The Algorithm, Emmy‑award winning Wall Street Journal and Guardian contributor Hilke Schellmann delivers a shocking and illuminating exposé on one of the most pressing civil rights issues of our time: how AI has quietly, and mostly out of sight, taken over the world of work. Schellmann takes readers on a journalistic detective story, meeting job applicants and employees who have been subjected to these technologies, playing AI-based video games that companies use for hiring, and investigating algorithms that scan our online activity to construct personality profiles— including if we are prone to self -harm. She convinces whistleblowers to share r

結合迷宮、找找看與記憶遊戲的全彩活動書，帶領孩子進入瑪利歐的冒險世界。內容豐富、互動性高，讓讀者在遊戲中培養觀察力與思考能力，是粉絲不可錯過的趣味讀物。Here we go! Super MarioTM fans will love this full-color activity book starring Mario, Luigi, and other characters from the beloved Nintendo(R) series. Super MarioTM fans of all ages will love this full-color activity book featuring Mario, Luigi, Princess Peach, and more friends and foes from the Mushroom Kingdom. With tons of fun word searches, memory games, search and find puzzles, boss crafts and mazes, Super Mario fans will love to power up with this super-interactive book! Mario first appeared in 1981 with the arcade classic Donkey Kong TM, and has since gone on to star in many adventures, allowing him to evolve into the beloved icon he is today. He is a video-game sensation, appearing across all genres--from action-platformers to sports, kart racing, and beyond.

臨床療效是醫學的生命！離開臨床無醫學。 本書「中醫臨床研究與應用」，由陳麒方、皮國立兩位教授學者主編，共收錄9篇文章以及1篇中醫臨床醫學雜誌論文總清單。文章作者群涵蓋美國、中國、印度、新加坡、台灣的醫藥衛生領域20位專家學者，文章主題包含：探討針灸SWOT分析、故宮古畫灸療圖的研究、濃縮生藥的藥品管理專題討論、江戶漢醫針灸書研究、日本時代台灣漢醫著作研究、遣唐使傳播的經方書貞元《傷寒論》、溫病時方的方劑研究、中醫背痛防治、住院會診醫案。另有目前發行時間最長的台灣中醫藥期刊《中醫臨床醫學雜誌》論文總清單900篇完整書目。本書對臨床醫學各個面向不論是鍼灸、藥品、醫學典籍應用、醫藥文化、中醫證候治療、醫史發展，都有論述，是一本相當有意義的中醫學術書。 This book "Research and Application of Eastern Clinical Medicine" is edited by two scholars, Prof./Dr. CHEN Chi-Fang and Prof. PI Kuo-Li. It contains a total of 9 articles and a comprehensive list of articles in Taiwan Journal of Clinical Chinese Medicine (TJCCM). Group of the article covers 20 experts and scholars in the field of health from the United States, China, India, Singapore, and Taiwan. The topics of the article include: SWOT analysis of acupuncture, research on moxibustion therapy pictures in ancient paintings, special discussions on drug management of concentrated crude drugs, Edo period han medical acupuncture books, research on Chinese me

This book describes in detail a research project dedicated to liquid-particle flow using ultrasound techniques. The project consists of theoretical, experimental, data science, finite element modeling, mechanical design and project management components. The objective of the project was to develop the ultrasonic methodology for measurement and characterization of liquid flow containing solid particles, in online (real-time) measurement conditions. The project consists of primary and complementary studies. The primary studies comprise development of the ultrasonic methodology for the simultaneous measurement of the average particle concentration and flow speed parameters. The developed methodology is based on the ultrasonic attenuation spectroscopy and the sound speed measurement methods, supported by data science programs. The complementary studies include acoustic streaming, designing a small-scale rotational test cell with an annular flow channel, testing it for various applications

「軟體開發者與資料科學家必備的實戰資源！Ali以深厚技術與清晰教學，手把手帶你用FastAPI打造可上線的生成式AI服務，從實作中保持領先地位。」 ―Joe Rowe，Applied Data Science Partners技術保證與合規主管 「這是一本極實用的生成式AI入門書籍，詳盡說明如何打造真正能運作的服務，非常適合當成邁入 AI 開發領域的首選書籍。」 ―Julian Brendel，Vitol資深Python開發者 準備好要用生成式AI打造真正可上線的應用程式了嗎？ 本書以實作為核心，教你如何運用FastAPI網頁框架來設計與部署AI服務。你將學到如何整合模型，處理文字、圖像、音訊與影片，並讓服務與資料庫、檔案系統、網站與API自然串接。無論你是網頁開發者、資料科學家，還是DevOps工程師，本書提供的範例、工具與策略，都能幫你打造高效、可隨需擴展、能即時提供服務的AI應用程式。 作者Alireza Parandeh透過清楚的解說與實際範例來介紹身分驗證、並行、快取，同時結合向量庫的檢索增強生成（RAG）技術。你將學會如何檢驗AI輸出品質、提升效能，以及保護微服務的最佳做法，並利用Docker來部署容器，在雲端自信啟動你的AI應用程式。 • 建立可與資料庫、檔案系統、網站及API互動的AI服務。 • 管理並行的AI工作與長時間運行的任務。 • 透過WebSockets與伺服器傳送事件（SSE），以串流形式傳送AI生成的結果。 • 使用身分驗證、內容過濾、限流與速率限制機制來保護服務。 • 透過快取、批次處理與微調技術強化AI效能。 Alireza Parandeh 是獲得英國工程委員會（UK Engineering Council）認證的特許工程師（Chartered Engineer），也是微軟與Google認證的開發者、資料工程師與資料科學家。 #FastAPI #生成式AI #AI服務/應用開發 #RAG #Docker部署AI #Context-rich AI

An Indigenous hunter laments the decline in the flying squirrel population and reflects on how animals perceive the world. In a drought-stricken cyberpunk anytown, kids revolt against the grown-ups only to face off with stray dogs over water. During late-night diving sessions, a researcher encounters a mysterious group of ocean-dwelling people with gills. In an overpopulated future, marrying an AI spouse will raise a human's credit score. A man follows the trail of an extinct leopard, seeking to unravel a metafictional mystery left behind by his late wife. This anthology showcases cutting-edge works on ecological themes by essential and emerging Taiwanese authors, revealing the vitality of their engagements with environmental crises. Taiwan is a biodiversity hotspot and geopolitical flashpoint, home to both Indigenous peoples and settlers. The pieces collected in A Taiwanese Ecoliterature Reader give voice to this human and more-than-human diversity, telling tales that are disturbing y

The hit danmei/Boys' Love novels (originally released in Chinese) that inspired animation and the comic/manhua—also available from Seven Seas!In an ancient China where magic has been nearly extinguished, two young men must work together to prevent the destruction of all life. (Takes place in the same universe as Legend of Exorcism.)Once, ancient China was brimming with magic...but three hundred years ago, the Spiritual Qi of the Heavens and Earth dried up in the Silence of All Magic. Hundreds of years with no spiritual qi have allowed resentment to build unchecked, and it’s only a matter of time before calamity descends and the world is plunged into chaos and destruction. Once-powerful exorcists have done their best to preserve their legacy in the centuries since, but now only one remains: Chen Xing, now tasked with venturing out into the war-torn world to prevent the impending apocalypse.Chen Xing’s sole magical ability is the heart lamp, a supernatural light source that’s supposed to

A deliciously thrilling new novel about a mysterious threat that puts targets on the backs of a group of roommates, from the author behind the "darkly funny, hilariously twisty, and completely charming" (Jennifer Close, New York Times bestselling author) Swiped. Kirby Cornell needs a break--particularly from her crumbling apartment in a sleepy town that is only known for serial killer in the '90s, her dead-end job, her sleazy landlord, her sloppy housemates, and, most of all, the terrible thing they all did. Luckily, that hasn't caught up with her just yet. Until a new message in their old group chat pops up from ex-roommate Esme: "Everyone in the group chat will die." The threat isn't the most disconcerting part of this--it's the fact that Esme died a year ago. With his signature "plot twists and wicked" (Margarita Montimore, USA TODAY bestselling author) prose, L.M. Chilton proves that he is a wickedly entertaining author to look out for.

An official Minecraft manga adventure! Peaceful life in a perfectly constructed town bores ten-year-old Nico into mischief. Riding Creepers while they explode is fun and all, but what he really wants is to escape the blocky confines of his home and take his crafting skills on an adventure to the ends of the world. Just how big is the world, anyway, and what could possibly stand in his way? Nico's journey, following his father to the end of the world, has reached a new level of intensity! He's gathered friends who adventure alongside him, explored a whole lot of the world, and helped a ton of people. What's next? What in the world is Enderman?!

Explore the brutal massacre of Isstvaan V in this fantastic stand-alone Horus Heresy title from Black Library.Horus has rebelled against the Emperor by purging his and his brother’s Legions, but what was supposed to be a secret act of murder has been revealed. In the Emperor’s name, Rogal Dorn and Malcador the Sigillite dispatch the largest force of legionaries and primarchs ever assembled to end Horus’ rebellion before it can begin. But the loyalists, on their way to enact vengeance, do not know the depth of the betrayal they face. They will not be the perpetrators of a massacre, but its victims. The last hope of returning to the Great Crusade and the unity of the Imperium will die in the dust of Isstvan V, and all those that survive will live in a new age of darkness.

★ 英國No.1暢銷兒童小說！《絕對笑噴》作者Adam Kay爆笑新系列★ BBC即將改編電視特別節目，話題度滿滿★ 10歲天才醫生出診中！醫院、學校與人生問題一起爆走★ 醫學知識 × 爆笑橋段 × 成長故事，笑到停不下來從很小的時候開始，大家就知道——Dexter Procter不是普通小孩。他出生四秒就開口說話；三歲就拿到87張A-level證書；十歲時，已經在醫院當兒科醫生！但即使是天才，也有煩惱。Dexter不太會交朋友，還得面對討人厭的宿敵醫生Dr Drake。更糟的是，他以前的學校突然爆發一場史上最可怕的災難——所有老師同時得了超嚴重的腹瀉！Dexter能不能一邊保住醫院的工作，一邊拯救整所學校，還順便找到自己在世界上的位置？The highly-acclaimed, No. 1-bestselling children's fiction debut from Adam Kay - and soon to be a BBC TV special!It was clear from an early age that Dexter Procter was different. He started speaking at four seconds old.By the age of three, he had 87 A-levels, from Afrikaans to Zoology. And by ten, he was working as a paediatrician at Lilydale General Hospital. Despite a loving but annoying family and a couple of good friends (Rupi and Otto), Dexter’s always struggled to fit in.Add to this a mortal enemy (Dr Drake) and a major problem at his old school (all the teachers struck down with awful diarrhoea) – will Dexter be able to save his job, save the school and find his

全球最受歡迎的海盜與寶藏的冒險傳奇故事近百年來改編最多的影視原典關於本書 英國文學家R・史蒂文生（一八五〇～一八九四）為英國蘇格蘭小說家詩人，也是英國新浪漫主義的代表之一。為世界著名的冒險故事和旅遊散文作家。 他從小酷愛文學，惜自幼體弱，後又罹患肺病，不得不經常易地治療。 其他作品包括：《黑箭》、《化身博士》、《島上夜譚》等等。 他的作品繁多，構思精巧，其小說富獨創性和力量。 最膾炙人口的小說《金銀島》，起初在雜誌上連載，後於一八八三年成書問世，被認為是冒險教育小說。使他一舉成名！ 這部小說的寫作技巧高超，氣氛、人物和情節十分合拍，是男女老少都喜愛的驚險故事。 此書曾多次改編成電影、動畫，風靡全世界千萬影迷；同時它也是海盜故事的鼻祖，西方的父母有時訓練孩子獨立性格的成長，第一件事就是告訴孩子——去讀史蒂文生的《金銀島》吧！

A chance meeting on a train to Tokyo sends two girls named Nana on a collision course with destiny! After a string of epic romantic failures, Nana Komatsu is ready to take control of her life and get a clean start in the big city. After prioritizing her musical ambitions over love, Nana Osaki is ready to stomp her way to the top of Tokyo's punk scene. With determination in their hearts and dreams in their eyes, the two Nanas are ready to take the world by storm! This is the story of two 20-year-old women who share the same name. Even though they come from completely different backgrounds, they somehow meet and become best friends. The world of Nana is a world exploding with sex, music, fashion, gossip, and all-night parties. Living in Tokyo is proving harder than either Nana expected. Nana K. can't seem to outrun her bad luck in love, and Nana O. can't seem to avoid the constant reminder of her ex-boyfriend's success. Can the brand-new besties help pick each other up, or will doom and

Learn how many different Asian communities celebrate Lunar New Year in this book for young readers that reveals why the first new moon of the year is such a culturally significant moment for many countries!This fact-filled book covers all things Lunar New Year, from the Chinese Zodiac animals to the details of modern celebrations in busy cities like San Francisco, Vancouver, and London. During today's celebrations, children receive money from their elders in red envelopes and people exchange gifts. Some rituals that people do for Lunar New Year include spring cleaning, sweeping away bad luck, and wearing new clothes. Young readers will learn about the Lunar New Year traditions of China, Korea, Vietnam, the Philippines, and Thailand in this book about the beloved holiday.Series Overview: A natural expansion of the exceptional Who Was? series, What Was? focuses on compelling historical events, great battles, protests, and discoveries.

Ember and the other pets come face-to-face with an evil dino-snake duo that's out to ruin the Chin family garden!Pick a book. Grow a Reader!This series is part of Scholastic's early chapter book line, Branches, aimed at newly independent readers. With easy-to-read text, high-interest content, fast-paced plots, and illustrations on every page, these books will boost reading confidence and stamina. Branches books help readers grow!Ember comes face-to-face with the strangest villain yet: the dino-snake! When an evil turtle and sly snake team up against the pets to take over the Chin family garden, the odds are stacked against them. The pressure is on for Ember to come up with the perfect plan or he'll get kicked out of his own backyard! Will Ember be able to protect his family's territory before the evil dino-snake duo take over the garden forever?With laugh-out-loud humor, engaging artwork on every page, and nonstop action that will have readers rushing to turn the pages, Pets Rule! is t

BLACKPINK in your area! Read all about the record-breaking K-pop girl group in this beautifully illustrated collectible Little Golden Book!Since their debut in 2016, BLACKPINK has taken the world by storm with their catchy songs, powerful performances, and awesome style. Read about Jisoo, Jennie, Rosé, and Lisa—from their childhoods and their time training in South Korea, to becoming the biggest girl group on the planet and their world concert tours.This Little Golden Book Biography is perfect for BLACKPINK fans of all ages, BLINKs, and people looking for inspiring stories about talented young musicians. Little Golden Book biographies feature the iconic gold-foil design and share the life stories of extraordinary artists, world leaders, performers, and athletes, including:BTSTaylor SwiftThe BeatlesLady GagaHarry StylesSeries Overview: LITTLE GOLDEN BOOK BIOGRAPHIES introduce fascinating people including artists, world leaders, performers, and athletes to young readers. With informative

這部精美的繪本將帶領讀者穿梭於全球各大城市，透過書中孩子們的視角，我們將看到農曆新年不只是家家戶戶的團圓飯，更是世界各地充滿火熱煙火、舞龍舞獅與燈籠遊行的盛大嘉年華。Find out all about Lunar New Year and how it is celebrated in different communities across the world!This stunning picture book is the perfect introduction for little ones to Lunar New Year celebrations. The most colourful time of the year is celebrated in communities around the world and you can now discover how it's celebrated through the eyes of the children who live there. Meet families in China, Vietnam, Singapore, Thailand and Indonesia, as well as in bustling cities like San Francisco, London, Sydney and Toronto and join them in their celebrations at home and on the streets in parades, lantern festivals and in temples.Packed with fascinating facts, young readers will love finding out all about different Lunar New Year traditions in this gorgeously illustrated picture book.

"Ridiculously fun."--Dav Pilkey, creator of Dog Man and Captain Underpants"Hilarious." -- New York TimesPizza, soup, and . . . paperclips? The first three tales of the intrepid heroes in the New York Times and #1 Indie bestseller series The First Cat in Space come together in this 3-book box set.When the spacewaves are in danger, there's only one hero who can save the day--First Cat!In The First Cat in Space Ate Pizza, First Cat journeys across space accompanied by the Moon Queen and LOZ 4000 to stop nefarious rats from eating the Moon.In The First Cat in Space and the Soup of Doom, the Moon Queen has been poisoned--by SOUP! With few she can trust in her own royal court, she and First Cat must find the antidote before time runs out.And in The First Cat in Space and the Wrath of the Paperclip, our fearless heroes face their most diabolical villain yet--an AI paperclip named CheckMate. Can our trio stop CheckMate from turning everyone into paperclips?Find out all of this (and more!) in t

【書籍特點】☆Transformer：自注意力、多頭注意力、位置編碼☆GPT：文字生成、Greedy Search、Beam Search、困惑度評估☆BERT：遮罩語言模型、預訓練、微調、分類任務☆ViT：影像分塊、視覺嵌入、注意力量化☆微調方法：Adapter Tuning、LoRA、P-Tuning☆資料處理：文字清洗、分詞、嵌入向量、資料增強☆混合精度與分散式訓練：Data Parallel、Model Parallel、梯度累積☆對比學習與對抗訓練：SimCLR、GAN、自監督任務☆最佳化器：AdamW、LAMB、動態學習率、Warmup、餘弦退火☆模型壓縮：知識蒸餾、教師學生架構、權重剪枝☆訓練流程：Tokenization、多GPU訓練、訓練中斷與恢復☆微調實作：資料集切分、層級凍結、超參數調整、推理量化【內容簡介】本書共分為12章，涵蓋大模型的建構、訓練與微調流程。第一章介紹Transformer的基本原理，包括自注意力、多頭注意力與位置編碼。第二章說明GPT模型的文字生成機制與實作方法，並比較Greedy與Beam Search等生成策略。第三章講解BERT模型的編碼結構與遮罩語言模型任務，並說明如何應用於分類任務。第四章介紹ViT模型在影像分塊、嵌入與注意力運算上的應用。第五章說明Adapter Tuning、LoRA、P-Tuning等常見微調方法。第六章說明資料清洗、資料增強與嵌入向量生成等處理技術。第七章解釋混合精度訓練、多GPU併行與梯度累積等效率優化技術。第八章涵蓋對比學習與對抗訓練，包括SimCLR與GAN的實作細節。第九章介紹AdamW與LAMB最佳化器，並比較各種動態學習率排程方式。第十章說明知識蒸餾與剪枝，包括教師學生架構與多頭注意力精簡方法。第十一章示範大模型訓練流程，從資料前處理到訓練中斷與恢復。第十二章介紹模型微調的實作，包括資料集切分、參數設定與推理效能調整。

???重量級Claude Code手冊??????涵蓋最新更新Agent Skills內容??????從新手晉升為高手???★內容介紹☆Vibe Coding 時代第一名的 AI 開發助手 Claude Code☆☆專案從零到好，Spec Driven Development 的完美實踐☆沒有疑義，真正的開發「功夫皇帝」- Claude Code，自推出之後儼然成為 CLI 領域最強大的存在。Claude Code 的母公司 Anthropic，正是全球頂尖模型 Claude Sonnet 的研發者，自己的產品搭配最棒的模型，再加上 Cursor 或 VS Code 這類 IDE 的加持，成為你專案的主控中樞。最新 Claude Code 的功能自然完全對齊其 CLI 的特性，有最適合 CLI 的斜線指令、自訂模式、Hooks 系統，settings.json 的深度客製作。而在 AI 的應用方面，更支援了平行處理的 SubAgent、計劃模式、MCP、號稱平替 MCP 的 Agent Skills。在 Spec Driven Development 的完美實踐上，Claude Code 更支援了插入外掛、GitHub 自動回覆 Issues/PR 的 Action，支援主流的 Spec Kit、CCPM等規範，更可以和雲端的模型以及用 Ollama 串接的模型用 LiteLLM 整合。再加上本書完整的實作專案，想成為 Vibe Coding 的頂尖菁英，一本書就讓你從見習生直接跳級成大魔王。★書籍特點☆Agent/SubAgent/多平行Agent/計劃模式/全自動模式/多輸出模式/☆最強 Sonnet 4.5 模型產生任何資料，程式碼、文件、規格、最新Agent Skills☆最棒的上下文管理，自訂指令、Hooks，Plugins、全專案索引、斜線指令☆無限制的工具使用，60 個最常用的 MCP Servers，比 Context7 還強的 Exa☆Jupyter部署到Streamlit雲端平台、Huggingface串AI照片辦識卡路里☆無伺服器 Vercel/Neon結合手機電商平台開發，Xcode 開發 iOS 天氣 App☆LiteLLM/Vertex AI/Ollama 串接Gemini 2.5 Pro 最新及未來模型☆幫你用 Unsloth 訓練推理

ALos Angeles TimesBook Prize FinalistANew York Times' "Best Thriller of the Year"In the vein ofThe Bad Seedcomes a twisty, atmospheric psychological suspense about a meddlesome elderly guest at a decadent luxury hotel who believes she has left her problematic past behind, until she decides to interfere in the lives of a young mother and her eight-year-old son, and finally meets her wicked match.The war between age and youth has never been so vicious.Eighty-one-year-old widow Maggie Burkhardt came to the Royal Karnak to escape. But not inquitethe same way as most other guests who are relaxing at this threadbare luxury hotel on the banks of the Nile. Maggie, a compulsive fixer of other people’s lives, may have found herself in hot water at her last hotel in Switzerland and justmighthave needed to get out of there fast... But here at the Royal Karnak, under the hot Saharan sun, she has a comfortable suite, a loyal confidante in the hotel manager, Ahmed, and a handful of sympathetic friend

本書內容分為三大部分︰敘述統計篇、推論統計篇、實驗設計篇。敘述統計篇主要介紹次數分配、集中量數、變異量數、相對地位量數，接著導入推論統計篇，介紹了常態分配、積差相關、迴歸分析、區間估計與假設檢定、卡方檢定法等議題，最後介紹實驗設計中常用的單因子、二因子變異數分析。 作者以統計學專業背景，力求讓讀者了解統計公式的意涵及其應用，希望初學者不因公式繁瑣失去學習的初心，這也是作者多年來教學相長的期許。同時透過圖形解說幫助初學者了解公式計算過程的實質意義，尤其在假設檢定章節的圖形解說，是一些教科書所闕如的。 本書內容適合教育系、心理系、輔導與諮商學系大學部學生或研究生統計課程的需求。每章所附習題可供讀者練習，有助於內文的理解，一些題目亦附有R程式，對於讀者未來學術或工作上必有所助益。

In Frank Miller and David Mazzucchelli’s Daredevil: Born Again, the comic’s titular hero has his life destroyed after his most menacing enemy learns his real identity. His attempts to rebuild his life and sanity result in one of the most gripping and impactful super hero storylines of all time. Released in 1986, the storyline is an extraordinary exploration of what happens when a hero’s identity is revealed, and his personal life completely annihilated. We see Daredevil reduced to the lowest depths in the character’s history, but we also follow his painstaking path toward redemption.This entry in MARVEL AGE OF COMICS explores Daredevil: Born Again’s gorgeous and unique artwork, the lasting impact of its story and art, and how it forever changed the ways super hero characters and their secret identities have functioned.