Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Discover this gothic tale of outcasts, friendship and Notre-Dame Cathedral in Paris. When French author Victor Hugo wrote Quasimodo’s story in 1831, he wanted to make people think about what it meant

A world of enchanted injustice needs a disenchanting woman in an all-new fantasy series by the Wall Street Journal bestselling author of The Paper Magician.The orphaned Elsie Camden learned as a girl that there were two kinds of wizards in the world: those who pay for the power to cast spells and those, like her, born with the ability to break them. But as an unlicensed magic user, her gift is a crime. Commissioned by an underground group known as the Cowls, Elsie uses her spellbreaking to push back against the aristocrats and help the common man. She always did love the tale of Robin Hood.Elite magic user Bacchus Kelsey is one elusive spell away from his mastership when he catches Elsie breaking an enchantment. To protect her secret, Elsie strikes a bargain. She’ll help Bacchus fix unruly spells around his estate if he doesn’t turn her in. Working together, Elsie’s trust in—and fondness for—the handsome stranger grows. So does her trepidation about the rise in the murde

Maid to Queer is the first book about Asian female migrant workers who develop same-sex relationships in a host city. Based on participant observation and in-depth interviews with Indonesian domestic

The perfect gift for fans of PaddingtonWelcome to the wise and wonderful world of everyone’s favourite bear.Paddington Bear is a beacon of happiness – well meaning, funny and always kind.Explore Paddington’s unique and universal take on life in this very special collection of warm words about friendship, family, love, laughter … and everything in between.

Floating across the sky in her hot air balloon, Cassi watches a little swift dive and swoop through the still air. In the rising sun the world seems to be holding its breath. Then a small breeze stirs

There are three simple nine-piece jigsaws and a beautifully illustrated board book in this box. Little children can enjoy a selection of detailed winter wonderland scenes in the book, and then use the jigsaws to recreate three of the winter wonders-filled scenes.3款9片大拼圖+1本小書拼圖完成後尺寸為17*17公分

A lively retelling of the classic Aesop's fable for young English language learners, beautifully illustrated and full of character and humour. "Hello, I'm new here!" says Hare to slow, quiet old Tortoise. Hare talks very fast, and likes to run and jump, and before Tortoise can think twice, he has agreed to an impossible race. But maybe Hare is a little too confident, and Tortoise has a chance of winning after all? And maybe both Hare and Tortoise have some lessons to learn about determination, believing in yourself and winning and losing well. With fun activities after the story, and online audio in both British English and American English. Beautifully produced, with world-class full-colour artwork throughout, this classic story is retold in a fluent and natural style, made highly accessible for English language learners. This is part of a series devised and edited in collaboration with acclaimed ELT consultant Peter Viney.CEFR: A1 Lexile: 440L Key Stage: EYFS, KS1

Animals inspire their little ones to chase their dreams and reach for the stars in this modern classic-in-the-making from New York Times-bestselling author Beth Ferry and Caldecott honoree Molly Idle.

A group of clever animals find an unusual but warm and furry home during Alaska's long winter in Jan Brett's newest snowy adventure.Cozy is the softest musk ox in Alaska, with the warmest fur you ever

The fifth arc in the sensational My Weird School series, which in its first four arcs has sold more than 23 million copies worldwide! In this sixth installment, A.J. and the gang begin music lessons!A

Solar System ― Our Place in SpaceWith Science Comics, you can explore the depths of the ocean, the farthest reaches of space, and everything in between! These gorgeously illustrated graphic novels off

In this momentous 50th book in the critically acclaimed, multimillion-copy bestselling Little People, BIG DREAMS series, discover the life of Elton John, the piano wizard who rocketed to stardom with

Little Owl experiences his first snow and first winter in this perfect follow-up to Little Owl’s Night and Little Owl’s Day, now in board book!“Winter’s almost here!” says Little Owl, as he observes l

別被他可愛的外表騙了──這隻貓可是練過「Kat Fu」的都市傳奇英雄！《Cat Ninja》第1集揭開Claude的雙面生活：一方面是男孩的寵物貓，另一方面是面對壞蛋、機器人和住家老鼠對手時的超級忍者。本書以漫畫形式呈現，圖像與文字比例適中，適合剛轉換至長篇閱讀的小讀者。劇情融合了英雄故事的架構與家庭幽默，讓讀者在歡笑與冒險中了解「英雄」也可以是你家客廳裡的一隻貓。喜愛《Dog Man》或《Narwhal and Jelly》的讀者也會輕鬆上手。Beware, villains! Cat Ninja may appear to be nothing more than a silly internet meme. But he is evil's greatest enemy, and the silent master of Kat Fu and carpet scratching! From Epic! Originals, Cat Ninja is a hilarious graphic novel series about a lovable cat with a heroic alter-ego.Raised from a kitten by a kindly old ninja master, Claude now spends his days as the pampered house cat of an eleven-year-old boy. But when trouble arises, Claude dons his mask and springs into action as Cat Ninja―Metro City's secret protector! In Book 1 of the series, follow our feline hero’s early exploits as he tries to keep his secret identity under wraps while thwarting the evil plans of slimy thugs, rampaging robots, and a certain rodent nemesis who lives under the same roof!

The second installment in the highly illustrated Stick Dog series is now available in paperback!In this hilarious sequel, the dogs embark on their quest for hot dogs and they learn they’re not the onl

A timely and timeless picture book about immigration, refugees, acceptance, and tolerance from a NYT bestselling author. A young Parsi girl in modern times comes from India to live in America with her

Magical friends Unicorn and Yeti love to help each other!Pick a Book. Grow a Reader!This series is part of Scholastic's early reader line, Acorn, aimed at children who are learning to read. With easy-to-read text, a short-story format, plenty of humor, and full-color artwork on every page, these books will boost reading confidence and fluency. Acorn books plant a love of reading and help readers grow!Unicorn has a gift for Yeti. Yeti does not have one to give to Unicorn. Yeti loves to crunch icicles. Unicorn wants to try crunching them, too! Yeti thinks the dark forest is pretty. Maybe Unicorn needs to see the forest from a different perspective? These sparkly, laugh-out-loud stories with full-color artwork and easy-to-read text throughout are perfect for new readers!

Rediscover the laughter and cheer of Buddy the Elf in this adorable picture book for readers of all ages! Buddy the Elf has more Christmas spirit than anyone, but he’s never quite fit in with the

Celebrating science and the poetry of existence, this is a true story about time and chance, genetics and gender, love and death—all made more accessible to the young imagination in the concrete, finite life of one tiny snail named Jeremy.★ A Kirkus Best Book of 2021: A Best Informational Picture Book★ A Marginalian (formerly Brain Pickings) Best Children’s Book of 2021★ A Spirituality & Practice Best Spiritual Book of 2021Based on a real scientific event and inspired by a beloved real human in the author’s life, this is a story about science and the poetry of existence...The Snail with the Right Heart is a story about time and chance, genetics and gender, love and death, evolution and infinity—concepts often too abstract for the human mind to fathom, often more accessible to the young imagination; concepts made fathomable in the concrete, finite life of one tiny, unusual creature dwelling in a pile of compost amid an English garden. Emerging from this singular life is a lyrical un

聯合國教科文組織所屬國際文化紀念物與歷史場所委員會(ICOMOS)荷蘭國家委員會與臺灣水利環境科技研究發展教育基金會(TIIWE)聯手於2019年5月27日至29日期間，在臺灣舉辦全球首屆「2019水文化國際研討會(2019 International Conference 'Water as Heritage')」，本局將研討會各主題投稿文件，進行蒐集及彙整，集結成冊出版英文版論文集，以推廣分享

Watch six breathtaking landscapes from around the world transform in front of your eyes, in this beautifully illustrated book. With simple facts about the wildlife and plants that change through every

A star-scattered night, a brand new baby boy, and all the potential in the world… This is a poetic introduction to what it means to be a boy in the challenging times we live in, and all of the dazzlin

In Small Worlds Earth, explore nature up close. Look at what happens under the leaf litter in a forest, find out what lives in a single desert oasis, examine the top of a Brazil nut tree in the Amazon and much more. What will you find when you explore these small worlds? Prepare to be surprised by the variety of life on each page of this gorgeous lift-the-flap book.A fascinating exploration of the life and cycles in nature's small worlds.

只有不斷實際應考，才能掌握新制多益的出題趨勢！由日本多益教學專業團隊領軍，實際應考超過1000次多益測驗，分析出題趨勢和解題關鍵，破解990高分的祕密！Essence English School是日本第一的多益專門校，教學團隊每月進場，累積超過1000次以上的應考經驗，完全掌握多益的出題方向與陷阱，多年來已協助許多不同程度的考生，取得大幅進步的成績。為造福更多考生，結合師資團隊經驗與精準出題方向

What’s the Time in London? Find out in this adorable clock book! With a real clock face for children to practise telling the time, this soft-learning book gently teaches children about the hours of th

Tobias Klein explores applications of 3D printing in architecture, art, design and interactive media installations in order to create a fusion of contemporary CAD/CAM technologies built from natural m

This book, written by an internationally acknowledged pioneer in endocrine surgery, is intended as advice for aspiring medical professionals, in particular for young people from around the world who a

Longlisted for Blue Peter Book Awards 2022Imagination and adventure run wild in the most talked about middle grade debut of the year!A small village on a Jamaican island.A girl who doesn't remember the previous summer.A best friend who is no longer acting like one; a new girl who fills that hole in her heart.A summer of finding fallen mangos, creating made up games and dancing in the rain.Secrets she keeps from others...and herself.The courage to face the truth even in the toughest of storms.Inspired by the author's childhood experiences, When Life Give You Mangos is a celebration of island life as well as a rich, lyrical mystery.Read it...and don't spoil the unforgettable ending!A recommended read for classroom discussons and educators looking for diverse offerings. A wonderful story with great heart, mystery, and insight. Kereen Getten is a bright new voice. --Clare Vanderpool, author of Newbery Medal winner Moon Over Manifest and Printz Honor book Navigating EarlyA heartwarming

只有不斷實際應考，才能掌握新制多益的出題趨勢！由日本多益教學專業團隊領軍，實際應考超過1000次多益測驗，分析出題趨勢和解題關鍵，破解990高分的祕密！Essence English School是日本第一的多益專門校，教學團隊每月進場，累積超過1000次以上的應考經驗，完全掌握多益的出題方向與陷阱，多年來已協助許多不同程度的考生，取得大幅進步的成績。為造福更多考生，結合師資團隊經驗與精準出題方向

It's Halloween and Billy can't wait for the village Halloween Party. There's just one problem... his Mini Monsters are at the party too! Sparkle-Bogey's in the apple bobbing, Trumpet's in a pumpkin an

Shakespeare everyone can understand―now in new DELUXE editions! Why fear Shakespeare? By placing the words of the original play next to line-by-line translations in plain English, these popular guides

9780545639149 Rescue on the Oregon Trail (Ranger in Time #1)9780545639170 Danger in Ancient Rome (Ranger in Time #2)9780545639200 Long Road to Freedom (Ranger in Time #3)9780545639255 Race to the South Pole (Ranger in Time #4)9780545909785 Journey through Ash and Smoke (Ranger in Time #5)9780545909839 Escape from the Great Earthquake (Ranger in Time #6)9781338133905 D-Day ─ Battle on the Beach (Ranger in Time #7)9781338133950 Hurricane Katrina Rescue (Ranger in Time #8)9781338133981 Disaster on the Titanic (Ranger in Time #9)9781338134018 Night of Soldiers and Spies (Ranger in Time #10)9781338537949 Escape from the Twin Towers (Ranger in Time #11)9781338537963 Attack on Pearl Harbor (Ranger in Time #12)

'There's something I need you to help me with. When I say BOO, you say HOO. Are you ready?' Boo is little ghost who lives in a haunted house - and he is afraid of the dark. In I Say Boo, You Say Hoo,

Monocle has always been a champion of taking it slow. It has encouraged readers to dive into a lake and go for a run. To sleep well. To eat food whose makers are proud of its provenance. In a shouty, jabbing-finger moment in history, it has done its bit to argue for a new modern etiquette to be generous with our time, hospitality and forgiveness. Now its editors and correspondents have brought all of this together in The Monocle Manifesto for a Gentler Life, a book that urges us all to slow down, reconnect, make good things and see nice places. And it also knows when to wear a cheeky smile. Chapters include:• An illustrated guide to being nice, respecting your neighbour and controlling your social media rants.• Profiles of the happiest nations – and the least lonely too.• How to build a house that’s good for you and your family.• Essays from leading thinkers and great writers on what we can gain if we shift gear.• The businesses charting a better course – from management to pride in pr

In a small back alley in Tokyo, there is a café which has been serving carefully brewed coffee for more than one hundred years. But this coffee shop offers its customers a unique experience: the chanc

A New York Times best-selling series! Harlem’s favorite family returns in the third installment in the Vanderbeerkers series, wherein the Vanderbeeker kids find themselves racing to save their mother’

A young meerkat travels the world looking for Christmas in this witty and festive picture book full of cards that readers can flip open to read!Sunny Meerkat isn't quite sure if Christmas in the Kalahari Desert with his meerkat family is the right sort of Christmas. After all, there's no snow, no Christmas trees, and certainly no holiday treats! Sunny sets off on a journey around the world visiting robins, penguins, and reindeer in search of the picture-perfect Christmas...before realizing he might have left it at home after all.

Meet Siti Hasmah, a little girl, who wants to be a journalist, in a period when not every girl was sent to school. Watch what happens to her, her family, and country when World War II strikes. Walk in

Meet Siti Hasmah, a little girl, who wants to be a journalist, in a period when not every girl was sent to school. Watch what happens to her, her family, and country when World War II strikes. Walk in

Books one through ten of The Critter Club series are now available in one adorable paperback boxed set!In the small California town of Santa Vista, four best friends Amy, Ellie, Liz, and Marion help f