Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Stir up some sticky slime, build a Solar System with rubber bands, power a speed boat using soap, and construct an erupting volcano, all with Home Lab, exciting experiments for budding scientists. Inc

An interactive board book with hidden reindeer and winter animal surprises along with way! Tactile elements and delightful imagery will encourage the development of motor skills and early learning. Babies and toddlers will love lifting the big flaps to find five peekaboo surprises pop up from the pages, including Parker Polar Bear and Percy Penguin, making this board book a fun and easy story about winter animals. Pop-up Peekaboo! Reindeer provides lots of opportunities for parent-and-child interaction and hours of wintry fun.Journey through the snow and watch as a Rosie Reindeer finds each of her friends, wraps up warm and puts on her favourite boots. This winter pop-up book for 3-5 year olds includes:Hands-on play elements that build all-round learning skills. 5 flaps throughout the book to lift and find the pop-ups, helping to develop fine motor skills.Rhythmic, read-aloud text that aids language development. Rounded edges and chunky board book pages rigorously tested (and chewed) b

An interactive pop-up book that inspires hands-on learning with the help of garden creatures! Tactile elements and delightful imagery will encourage the development of motor skills and early learning.Bold, brightly coloured pictures, lift-the-flap pages and entertaining rhymes, Pop up Peekaboo: Garden provides lots of opportunities for parent-and-child interaction and hours of nature themed fun. Journey through the garden and find all the wildlife and habitats and lifecycles here!Babies and toddlers will love lifting the big flaps to find five peekaboo surprises pop up from the pages: a bright yellow sunflower growing taller and taller, busy honeybees gathering nectar and pollen, a spotty ladybird on a strawberry plant flower, a frog jumping across some waterlilies, and a cheery sparrow chirping in a cherry tree. Vocabulary about animal habitats are carefully woven throughout, making this board book a fun and easy story about gardens.Inside the pages of this adventure pop-up book, you’

About DK Super Readers Level 4 Knights and CastlesUse your reading superpowers to learn all about medieval knights and their castles - a high-quality, fun, non-fiction reader - carefully levelled to help children progress.Knights and Castles is a beautifully designed reader all about these incredible medieval fortresses.The engaging text has been carefully levelled using Lexiles so that children are set up to succeed.A motivating introduction to using essential non-fiction reading skills.Children will love to find out about why castles were built, some of the coolest castles, and medieval people's lives in and around them both in peace and wartime.

Trace India’s journey through its space program, from its early skywatchers, the myths and legends, and the dreamers in a newly independent country, to the visionaries who continue to inspire generations to look towards the stars.In 1947, a newly independent India struggled to manage its new borders, limited resources, and a burgeoning population. Almost instinctively, its leaders turned towards the skies, looking up and beyond to see how they could use technology and space to help their people. This wasn’t a new endeavour, however. Skywatchers in ancient India had always looked towards the stars, mapping them, giving them names, and building myths. So, new India turned towards the stars once again - using satellites to help with agriculture, forecast weather, and build better communication. Today, India’s space program has morphed into something larger. The country looks towards the stars―not to sustain itself, but to explore, to reach the final frontier, and to take its own place amo

Get ready for festive fun in a galaxy far, far away! Build a snow-droid. Add some festive sparkle to favourite LEGO (R) Star Wars (TM) characters, including Yoda and Darth Vader. Help Han Solo and Che

A frightfully fun LEGO (R) sticker book with more than 1000 Halloween-themed stickers. Step into the spine-chilling world of LEGO models that go bump in the night. DK's Halloween! Ultimate Sticker Co

Dive into our planet's largest and least explored world in this stunning encyclopedia of whales, waves, wrecks, wind farms, and everything oceanic!Using 3D illustrations and a level of detail you can'

This fun first board book shows it's never too early - or late! - to learn about big ideas, and build confidence in science. Just like your little one, Baby Robot is a brilliant scientist in the mak

Explore the laws and theories of physics in this accessible introduction to the forces that shape our Universe, our planet, and our everyday lives. Using a bold, graphic-led approach The Physics Boo

Little ones will love using their fingers to follow the glittery, bumpy shiny trails in DK's Follow the Trail Minibeasts.Help your toddler learn as they explore the lives of the butterflies, ladybirds

The amazing slime recipes in this book are sometimes gross, sometimes sparkly, sometimes smelly, but ALWAYS loads of fun. More than 30 innovative recipes, using inexpensive, accessible, and safe ingre

An exciting project-packed book of crafts, activities, and experiments for curious children who love to make, play, and explore. With clear step-by-step instructions and photos, children will learn ab

Full of hands-on activities that will tap straight into your child's natural scientific curiosity. The experiments are easy to follow and use items that most people already have tucked away at home.Lo

Little ones will love using their fingers to follow the glittery, bumpy shiny trails in DK's Follow The Trail Wild Animals. This tactile board book is packed with colourful illustrations to help encou

DK’s best-selling illustrated encyclopedia series explores the fantastical world of myths and legends. Discover stories from myth and legend as you've never seen them before through incredibly detailed 3D illustrations in this encyclopedia for children aged 9+. Knowledge Encyclopedia’s clear explanations, illustrations, photographs and 3D images will engage children in complex subjects.Find yourself transported to a realm of myth and legend with this perfect gift for anyone who loves stories of gods, monsters and heroes. This all-encompassing myth encyclopedia for kids offers:An impressive collection of facts, charts, timelines and illustrations. A visual approach using illustrations, photographs and extremely detailed 3D CGI images.Clear explanations and retellings of different myths and legends from around the world. Children can explore mythology in a new and exciting way through spectacular computer-generated images of key heroes, gods, monsters and locations. This new book in the

DK’s best-selling richly illustrated encyclopedia series explores the wonderful world of science. Learn the ins and outs of science as you’ve never seen it before, through incredibly detailed 3D illustrations, in this encyclopedia for children aged 9+. Knowledge Encyclopedia’s clear explanations, illustrations, photographs, and 3D images will engage children in complex subjects.This impressively detailed encyclopedia uses awesome illustrations to show biology, chemistry, and physics in the world around us. This all-encompassing science encyclopedia for kids offers:An impressive collection of facts, charts, timelines and illustrations. A visual approach using illustrations, photographs and extremely detailed 3D CGI images.Clear explanations of physics, chemistry, and biology, as well as space exploration, the latest technology, wonderful wildlife, and our amazing bodies. Children can explore science in a new and exciting way. Learn about groundbreaking topics like looking inside a cell,

Set off on an exciting journey to meet the Pokémon of Paldea, in this Level 1 Super Reader!Discover their friendships, special skills, and the awesome mysteries they hope to uncover.The engaging text has been carefully leveled using Lexile so that children are set up to succeed. Colorful Pokémon images, clear vocabulary, and a fun quiz will help young readers build their reading ability, as they uncover the exciting secrets of Paldea.

Discover the secrets of Pokémon battles, in this Level 2 Super Reader!Learn how to catch, train, and get the best out of your Pokémon team. Captain Pikachu and his friends will show you how!The engaging text has been carefully leveled using Lexile so that children are set up to succeed. Colorful Pokémon images, clear vocabulary, and a fun quiz will help young readers build their reading ability as they uncover the exciting secrets of Pokémon.

DK’s best-selling richly illustrated encyclopedia series explores the wonderful world of transport. Knowledge Encyclopedia: Transport! uses incredibly detailed 3D illustrations to show children aged 9+ everything they need to know about how vehicles work. Children will find themselves totally absorbed in complex subjects with the Knowledge Encyclopedia series, made clear through engaging explanations, intricate illustrations, vivid photographs, and striking 3D images.Meet hundreds of vehicles that float, fly, or speed across the land, including the record breakers - the fastest, largest, longest, and strangest modes of transportation ever to zoom, sail, or soar. This all-encompassing encyclopedia for kids offers:- A whole collection of facts, charts, timelines, and illustrations that cover a vast range of transportation. - Complex subjects that are explained using amazingly detailed CGIs that entice young readers to dive in and explore.- A visual approach using illustrations, photograp

Meet the sea creatures living on a coral reef! Make reading your superpower with DK's beautiful, leveled nonfiction. Use your reading superpowers to learn all about a beautiful coral reef and the sea animals living there - a high-quality, fun, nonfiction reader - carefully leveled to help children progress. Fishy Tales is a beautifully designed reader all about the fish and other sea animals living on a coral reef. The engaging text has been carefully leveled using Lexiles so that children are set up to succeed. A motivating introduction to using essential nonfiction reading skills. Children will love to find out about the beautiful coral reef and all the sea animals that can be spotted on it.

Let's go outside and discover everything nature has to offer!How many legs does a spider have? Can you help spot the nighttime animals? From ferny, forest floors to white, sandy beaches, babies and toddlers will love journeying through the different environments to discover the variety of wildlife that lives in our surroundings. Each section of this engaging and educational book is dedicated to a different habitat, such as forests and mountains. Bright, colorful photographs illustrate each word, with easy-to-read labels so your little one can sound out the words with you. The interactive book encourages children to match up animals and their homes, and count which animals on the page can fly. This delivers a rounded early learning reading experience, and helps your little one develop early speaking, listening, and observation skills. The book has strong board pages made especially for young children. The chunky tabs along the top and side are easy to grab to help with early motor cont

Let’s meet animals from around the world.What lives at the bottom of the ocean? What are your favorite pets? From creepy-crawlies to massive mammals, babies and toddlers will love discovering which animals squeak, squawk, and oink! Each section of this engaging and educational book is dedicated to different types of animals, such as farm and sea animals, with bright, colorful photography of each species. There are easy-to-read labels so your little one can sound out the words with you. The interactive book encourages children to count the tropical fish, pretend to talk like a parrot, and find the animal with a long trunk. This delivers a rounded early learning reading experience, and helps your little one develop early speaking, listening, and observation skills. The book has strong board pages made especially for young children. The chunky tabs along the top and side are easy to grab to help with early motor control. Preschoolers will quickly recognize the picture on the tab which w

Discover the wonders of our rocky planet!This amazing deck of cards welcomes you to Earth's extraordinary minerals and gems, from sparkling emeralds to igneous rocks formed deep inside the Earth’s molten core. Stunning pictures and fast facts enable you to grasp a wealth of knowledge in a fun way. Each card contains snappy and accessible information, displaying each rock or mineral in dazzling detail. The front of the card shows the rock with a clue of what it is. The back reveals the answer, plus a dataset of essential information, ensuring you can recognize sedimentary from sandstone, metamorphic from marble, and pyrite from pearl. You’ll discover the unique qualities of each material, together with how it is used in art, industry, architecture, and science. You can use the cards to test your own knowledge, or how about using them to play a guessing game, quiz, or competitive comparison game with a friend? Our World in Pictures: Rocks & Minerals Flash Cards are packed with informat

Ideal for home learning, this simple and inspirational book has everything you need to grasp grammar and punctuation, and master essential reading and writing skills.Need help telling your adjectives from your adverbs? Struggling to figure out what that poem is really about, or where to begin with your essay?Using short, straightforward explanations and clear graphics to shed light on the trickiest of topics, this is the perfect guide to understanding and using the English language. Illustrated examples make daunting grammar accessible and fun, and help develop an understanding that can be applied to school studies. Annotated texts complement concise, practical guidance to support students in developing sound analytical and writing skills. The carefully selected reading recommendations will inspire reading for pleasure, while clear links between topics will ensure that students not only understand language techniques but know how to apply them effectively.How to Be Good at Language Art

Ideal for home learning, this simple and inspirational book has everything you need to get to grips with grammar and punctuation, and master essential reading and writing skills.Need help telling your adjectives from your adverbs? Struggling to work out what that poem is really about, or where to begin with your essay? Using short, straightforward explanations and clear graphics to shed light on the trickiest of topics, this is the perfect guide to understanding and using the English language.Illustrated examples make daunting grammar accessible and fun, and help develop an understanding that can be applied to school studies. Annotated texts complement concise, practical guidance to support students in developing sound analytical and writing skills. The carefully selected reading recommendations will inspire reading for pleasure, while clear links between topics will ensure that students not only understand language techniques but know how to apply them effectively.How to be Good at En

Imagine if you could travel back in time and walk the streets of the past. Where would you go first? Incredible History turns back time to reveal realistic reconstructions of the most incredible locations and exciting moments in history. You’ll feel the roar of the crowd in the Roman Colosseum, walk the ramparts of the Great Wall of China, and ride the first railways. Each story begins with an archaeological site or artifact. You’ll learn when and how it was discovered, and what it teaches us about how the people who lived at the site might have spent their days. Then, you’ll see the location recreated in jaw-dropping 3D detail. Using archaeological evidence, the people and places of the past will be brought back to life before your very eyes. With each page packed with fantastic facts and extraordinary pictures, Incredible History brings together the best parts of history and archaeology to recreate the entire history of the world.

How did they make that using LEGO® bricks?Find out! Meet the professional builders behind some amazing LEGO® models and learn all about how these creative experts make masterpieces using LEGO bricks.

See how young animals grow and change in the first weeks and months of their lives with this series of animal books for young nature lovers. Everyone loves little animals and this book is a must for fans of cute pets. This elegant book follows baby animals in beautiful, crisp photography through their early lives--from helpless newborns to confident, curious creatures on the cusp of adulthood. Meet a playful puppy, a curious kitten, and a delightful baby rabbit and watch how they grow. A series of photographs shows each animal at different stages in its early life. See a bunny before it grows fur, kittens learn to hunt, and a puppy play with toys. These books are a delight to read aloud to preschool children or for young readers to pick up themselves. A must for all young fans of animals.

A book that helps toddlers adjust to using the potty in a fun and comfortable way. A charming and entertaining board book that helps toddlers adjust to using the potty in a fun and relatable way. Meet twins Johnny and Jasmine. It's time they started to try and use a potty and to wear pants. They HAVE pants, but Johnny just puts his on Teddy while Jasmine uses her potty as a slide for her toys! Follow along with the funny story as Johnny and Jasmine go through the ups and downs of their potty training journey, from getting comfortable with a potty, to positive reinforcement, hygiene, and understanding that accidents happen. Packed with handy tips and charming illustrations, Time To Use The Potty is the perfect way to introduce toilet training to your little one. Potty training has never been so easy - or so much fun!

Discover the rich and complex history of the peoples of Africa, and the struggles and triumphs of Black cultures and communities around the world. With profiles of key people, movements, and events, The Black History Book brings together accounts of the most significant ideas and milestones in Black history and culture. This vital and thought-provoking book presents a bold and accessible overview of the history of the African continent and its peoples - from the earliest human migrations to modern Black communities and the African diaspora. Powerful images and innovative infographics bring to life the stories of the early kingdoms of Ancient Egypt, Nubia, and Carthage; the powerful empires of the Medieval and Early Modern eras; and the struggle against European colonizers. Black history and culture beyond the African continent is also explored in detail - including the Atlantic Slave Trade; the quilombos (slave resistance camps) of Brazil; the Harlem Renaissance and Jazz Age; the "Wind

The simplest guide to astronomy and stargazing!Grasping astronomy has never been easier. The awe of the night sky will soon turn into knowledge of the constellations, planets, and astrological phenomena!Bold graphics and easy-to-understand text make this visual guide the perfect introduction to astronomy and stargazing for those who have little time but a big thirst for knowledge. Inside you'll find:- Simple, easy-to-understand graphics that help to explain astronomy, space, and the night sky in a clear, visual way- The latest astronomical information on black holes, gravitational waves, the origin of the Universe, and the planets of the Solar System- User-friendly star-charts that guide you through the sky using brighter stars as "signposts" to locate harder-to-see objects- Essential advice on the practicalities of stargazing - from observing with the naked eye to using telescopesEach pared-back entry covers the essentials more clearly than ever before.

Explore the magic of holidays at Hogwarts Features Harry Potter minifigure in Yule Ball robes. Enter the festive world of LEGO(R) Harry Potter(TM) and visit Hogwarts for a spellbinding winter holiday. Celebrate the season with your favorite LEGO Harry Potter minifigures and join them for a feast in the Great Hall. Admire the castle's decorations and get ready to hit the dance floor at the Yule Ball. Head to the Gryffindor common room to play a game of wizard chess, warm up in front of a roaring log fire, and join Harry as he exchanges gifts with friends. Sprinkled with festive scenes and the latest LEGO Advent Calendars, sets, and minifigures, this is the perfect gift for young LEGO Harry Potter fans. LEGO Harry Potter: Holidays At Hogwarts comes with a Harry Potter minifigure in Yule Ball robes. (c) & (TM) Warner Bros. Entertainment Inc. Publishing Rights (c) JKR. (s20). (c)2020 The LEGO Group.

Learn more than 1,000 of the most common and useful English phrasal verbs using the effective English for Everyone visual method. Phrasal verbs (two- or three-part verbs such as "put off", "put on", "

This picture word book of 1000 first science words is the perfect STEM book for helping children learn.This book introduces key scientific concepts while broadening children's vocabulary and strengthening their early reading and writing skills. Every picture-packed page is full of things such as sounds, light, senses, and machines, with words for each image. 1000 Words: Science clearly labels each picture, which encourages picture-and-word association and helps early reading. Each topic features questions that ask children to find things on the page or that stimulate thinking, talking, and early science skills. The words have been chosen with the help of a leading educational consultant, and include lots of useful nouns, plus some interesting adjectives, and common verbs. This fun and educational picture word book is a must-have first reference title for parents who are keen to develop their child's language, science, and literacy skills.

Babies and toddlers will fall in love with pandas while flipping through the pages of this interactive early learning book about these adorable animals. Meet the black and white panda family and their

Journey back in time and find out where dinosaurs roamed. This unique children's atlas explores each continent, revealing fossil sites and stories on every map. This atlas is packed with maps of early

Get set for a journey across the globe, visiting every country - from Afghanistan to Zimbabwe - to find out what makes each one unique. Along the way, you'll explore mountains, deserts, forests, and r

Some subjects are too interesting to be left at school! Carry on your love of history at home with Ancient Rome - an activity-packed exploration of people and places in this early empire. Divided into

This book empowers children by providing an affirmation for every single day of the year from January 1 to December 31.I am strong. I am brave. I can handle anything. Using the power of positive think