Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

America's favorite series returns with a new look and a Netflix tv show.Kristy, Mary Anne, Stacey, Claudia, and Dawn are the luckiest baby-sitters in the world. This summer they're going on the greatest trip ever: a plane ride to Florida, a boat trip around the Bahamas, and then three days of fun -- in Disney World!Of course they have a million adventures. Claudia gets notes from a mysterious Secret Admirer. Kristy, Mary Anne, and Stacey make some unusual new friends. Dawn has her first real romance. And they still have time for what they like best of all -- baby-sitting!

故事中的超級小兔是電玩世界中最會跑也最勇敢的角色，每本都有緊張刺激的任務要完成，超級小兔能闖關成功嗎？還是會被Game Over呢？Rabbit Boy is a super-fast and super brave, but he's also a video game character living in a video game world. What will happen when Sunny, the boy playing th game, loses each level? Will it be game over for Super Rabbit Boy and all his friends?#6 The Super Side-Quest Test!King Viking has a new giant robot to help him take over the Animal Town. Super Rabbit Boy must stop him, but he needs a secret item. And to get the item, he has to defeat a dragon, escape a dungeon, and avoid lots and lots of robots. Can Super Rabbit Boy finish all these quests in time to save Animal Town? Or will this latest Press Start! adventure put our hero to the test?#7 Robo-Rabbit Boy, Go!Uh-oh, Super Rabbit Boy is in big trouble. He's been kidnapped by Queen Spooky and her ghost troop! Without Super Rabbit Boy, Animal Town is scared. So meanie King Viking creates Robo-Rabbit Boy to help. Robo-Rabbit Boy is fast like Super Rabbit Boy and strong

在熱鬧水上樂園的角落，有一群被遺忘的充氣玩偶——火鶴、仙人掌、甜甜圈和西瓜，他們雖被遺棄，卻活力十足、幽默滿分。火鶴心中懷抱成名夢，當新波浪池吸引媒體到來，朋友們展開一場為他設計的「爆紅」行動。但來自火鶴過去的一群熟人突然出現，讓事情變得複雜起來。他是否準備好面對自己真正的故事？透過一群充氣角色，探討夢想、身分與友情。適合喜歡《Dog Man》和《The Bad Guys》的讀者，帶來一場想像力爆棚的歡樂旅程。The Inflatables don't get pumped. They stay pumped! Flamingo, Cactus, Donut, and Watermelon may be forgotten waterpark floats who live at the lost and found, but these inflata-pals are about to make some big waves in a funny graphic novel series that's perfect for fans of Dog Man and The Bad Guys!Flamingo is destined to be a star! So when the opening of a new wave pool brings camera crews flooding to the park, his inflata-pals hatch a daring plan to make him famous. But will a flock of familiar faces from Flamingo's past burst his bubble? Get ready, world -- Flamingo is about to BLOW UP!

★《紐約時報》暢銷作家二戰諜報力作★少女解碼 × 地下反抗軍 × 橫越法國生死任務★親情與信念交織的高張力歷史小說★給熱愛懸疑與勇氣故事的讀者657天前，梅格的父親離家參戰，從此音訊全無。她只剩下一罐父親留下的密碼紙條——那是他們之間的遊戲，也是她思念的寄託。直到有一天，她在雪地血跡中發現一名受傷的英國間諜。一項幾乎不可能的任務隨之展開：護送一個德國難民家庭穿越納粹佔領區，抵達中立的西班牙。而成功的代價，是換回父親的自由。納粹搜捕逼近，謎題逐漸解開。梅格明白，有些答案，可能比子彈更致命。From New York Times bestselling author Jennifer A. Nielsen comes a thrilling World War II story of espionage and intrigue, as one girl races to save her father and aid the French resistance.Six hundred and fifty-seven days ago, Meg Kenyon's father left their home in France to fight for the Allies in World War II, and that was the last time Meg saw him. Recently, she heard he was being held prisoner by the Nazis, a terrible sentence from which Meg fears he'll never return. All she has left of him are the codes he placed in a jar for her to decipher, an affectionate game the two of them shared. But the codes are running low, and soon there'll be nothing left of Papa for Meg to hold on to at all.Suddenly, an impossible chance to save her father fa

The wriggly, squiggly superhero is now available on CD with a whole host of fabulous friends! Join Superworm, Stick Man, The Highway Rat, Tabby McTat and The Ugly Five in these five fantastic stories and songs by the superstar children's book pairing, Julia Donaldson and Axel Scheffler, in a gorgeous box set. This CD box-set is perfect for entertaining children on long car journeys, or for simply sharing stories at any time of the day. Five favourite stories from the superstar creators of The Gruffalo and Zog Each CD includes the full story, a listening game and song, all acted superbly by the incomparable Oscar-nominated Imelda Staunton.The set includes Superworm, Stick Man, The Highway Rat, The Ugly Five and Tabby McTat Superworm is going to be an on-screen adventure starring Matt Smith and Olivia Coleman Christmas 2021 Celebrating 10 years of Superworm in 2022本盒裝CD對應以下五本繪本Superworm 9781407170725Stick Man 9780702319273The Highway Rat 9781407170732Tabby McTat 9781407170701The Ug

Owly, the little owl with a heart of gold, returns for another forest adventure in this Eisner-winning series about friendship!For Owly and Wormy, nothing beats the power of friendship! But fear can b

The perfect picture book for children with a big imagination, We Found a Cat is a laugh-out-loud story of a little girl and a little boy who find a furry friend. Cats have whiskers and love to purr... Cats love to play...Cats love to eat... When a brother and sister find a new furry friend, they decide that it most definitely is a cat. But something's not quite right.It's very loud... It's very hungry... And it doesn't use doors! They eventually decide that it is, after all, an *outdoors cat* and are very happy to leave it to all the outdoorsy things! Written and illustrated by the wonderfully talented Heidi McKinnon, author of I Just Ate My Friend A super hilarious read about two children who've become friends with a tiger! Full colour illustrations throughout in gorgeous orange and teal tones

Karen Brewer, Big SisterEverybody used to love Karen. She was cute. She was the littlest sister. But now baby Emily is in their family, and Karen feels left out.Then Emily gets sick and everybody has

Evil wizard Astrid brings the Garden of Beasts to life and the Dragon Masters must go into battle in the latest installment of this New York Times bestselling series!Pick a book. Grow a Reader!This se

His Dark Materials: Northern Lights 1The destiny that awaits her will take her to the frozen lands of the Arctic, where witch-clans reign and ice-bears fight. Her extraordinary journey will have immeasurable consequences far beyond her own world... Rankin's lens has exquisitely captured the bond between character and daemon; the soul of the stories The His Dark Materials trilogy is award-winning, internationally bestselling and a modern classic.His Dark Materials: The Subtle Knife 2"My hands shook, turning the pages." The Times "Only Rankin can light and photograph faces with such intensity and drama. I'm delighted with this vision of my story." Philip Pullman The second volume in the ground-breaking His Dark Materials trilogy, now with a breath-taking new cover creatively directed and photographed by the legendary Rankin. "What is he? A friend, or an enemy?" "He is a murderer." Will has just killed a man.He's on the run. His escape will take him far beyond his own world, to the eerie

"An astonishing imaginative feat - Pullman has conjured a universe of intensity and beauty that leaves one gasping" The Times "Only Rankin can light and photograph faces with such intensity and drama. I'm delighted with this vision of my story." Philip Pullman The third volume in the ground-breaking His Dark Materials trilogy, now with a breath-taking new cover creatively directed and photographed by the legendary Rankin. "We're going to the land of the dead and we're going to come back." Will and Lyra, whose fates are bound together by powers beyond their own worlds, have been violently separated.But they must find each other, for ahead of them lies the greatest war that has ever been - and a journey to a dark place from which no one has ever returned... Rankin's lens has exquisitely captured the bond between character and daemon; the soul of the stories The His Dark Materials trilogy is award-winning, internationally bestselling and a modern classic. Now a major BBC/HBO television se

"Remarkable writing: courageous and dangerous as the best art should be." The Times "Only Rankin can light and photograph faces with such intensity and drama. I'm delighted with this vision of my story." Philip Pullman The first volume in the ground-breaking His Dark Materials trilogy, now with a breath-taking new cover creatively directed and photographed by the legendary Rankin. Lyra Belacqua and her animal daemon live half-wild and carefree among scholars of Jordan College, Oxford.The destiny that awaits her will take her to the frozen lands of the Arctic, where witch-clans reign and ice-bears fight. Her extraordinary journey will have immeasurable consequences far beyond her own world... Rankin's lens has exquisitely captured the bond between character and daemon; the soul of the stories The His Dark Materials trilogy is award-winning, internationally bestselling and a modern classic.Now a major BBC/HBO television series, with an all-star cast of Ruth Wilson, James McAvoy, Anne-Mar

"My hands shook, turning the pages." The Times "Only Rankin can light and photograph faces with such intensity and drama. I'm delighted with this vision of my story." Philip Pullman The second volume in the ground-breaking His Dark Materials trilogy, now with a breath-taking new cover creatively directed and photographed by the legendary Rankin. "What is he? A friend, or an enemy?" "He is a murderer." Will has just killed a man.He's on the run. His escape will take him far beyond his own world, to the eerie disquiet of a deserted city, and to a girl, Lyra. Her fate is strangely linked to his own, and together they must find the most powerful weapon in all the worlds...Rankin's lens has exquisitely captured the bond between character and daemon; the soul of the stories The His Dark Materials trilogy is award-winning, internationally bestselling and a modern classic. Now a major BBC/HBO television series, with an all-star cast of Ruth Wilson, James McAvoy, Anne-Marie Duff and Lin-Manuel

Unicorn Bo and friends set off in search of The Golden Fish, a legendary demigod, the only person who can help merbaby Flo, who was born unable to swim on her own. On their journey, they meet a friend

A gripping graphic novel adaptation of Lauren Tarshis's bestselling I Survived the Attacks of September 11, 2001, in time for the 20th anniversary of 9/11.The only thing Lucas loves more than football

No fair!Karen is having a bad-luck day. Her favorite jeans are missing. There's no prize in the Crunch-O cereal box. And Boo-Boo the cat runs away from her!Karen tries everything to make her day bette

Moby Shinobi and his dog Toby are heading to the racetrack! Moby tries to use his ninja skills to help the crew, but ends up in a mess of oil spills, flat tires, and wrong turns. With some help from T

Discover tons of exciting pranks, jokes, and hijinks from the films of Harry Potter in this hilarious and interactive book with a paintbrush that reveals hidden messages.Ever wanted to tell a joke lik

King Viking, his robot army, and Miss Business are working together to create a perfect storm of trouble in Underland. It's up to Super Rabbit Boy and Mega Mole Girl to team up and save the day. But t

Newbery Honor-winning author Cynthia Lord has written a sensitive and accessible book about the challenges of fitting in when you know you're a little different.On the last night of summer, Emma tags

Claudia has always been the most creative kid in her class...until Ashley Wyeth comes along. Ashley's really different: She wears hippie clothes and has multiple earrings, and she's the most fantastic

Eight-year-old Violet and her new fairy friend Sprite are ready to send more pixies back to the Otherworld! When a tricky fairy named Jolt traps Violet's cousin, Leon, in a video game, things get dang

Who is that sitting in the hallway? What is itching underneath the cast? This scary story collection is perfect for beginning readers who are looking to be spooked. With simple text, creepy full-color

這部由MinaLima設計的《Harry Potter and the Sorcerer's Stone》特別版，不僅完整保留原著內容，更以近乎每頁皆有的全彩插圖與精巧的紙藝機關，賦予熟悉的故事全新面貌。從霍格華茲入學信到對角巷的入口，每一項互動設計都精緻且富趣味。適合珍藏，也非常適合作為導讀《哈利波特》系列的起點，邀請新讀者進入魔法世界的第一步。A dazzling new edition of J.K. Rowling's Harry Potter and the Sorcerer's Stone, fully illustrated in brilliant color and featuring exclusive interactive paper craft elements, including a fold-out Hogwarts letter and more!In this stunning new edition of Harry Potter and the Sorcerer's Stone, experience the story as never before. J.K. Rowling's complete and unabridged text is accompanied by full-color illustrations on nearly every page and eight exclusive, interactive paper craft elements: Readers will open Harry's Hogwarts letter, reveal the magical entryway to Diagon Alley, make a sumptuous feast appear in the Great Hall, and more.Designed and illustrated by award-winning design studio MinaLima - best known for establishing the visual graphic style of the Harry Potter and Fantastic Beasts films - this edition is s

9781338540390 Frog Meets Dog: An Acorn Book (A Frog and Dog Book #1)9781338540420 Goat in a Boat: An Acorn Book (A Frog and Dog Book #2)9781338540475 Hog on a Log: An Acorn Book (A Frog and Dog Book #3)

California continues to be ravaged by devastating wildfires. Lauren Tarshis's heart pounding story tells of two children who battle the terrifying flames and -- despite the destruction -- find hope in

A diverse cast of characters-Kamala Khan (Ms Marvel), Miles Morales (Spider-Man) and Doreen Green (Squirrel Girl)-team up in their first-ever illustrated middle-grade series about ordinary kids with e

America's favorite series returns with a new look and a Netflix tv show.Dawn has always thought there was a secret passage hidden in her house. But that doesn't explain why creepy things happen when D

I Survived meets The Puppy Place in this thrilling adventure novel as Ranger -- a time-traveling golden retriever -- races to the rescue on the day of the Pearl Harbor attack.Ranger travels back to 19

Bo and the unicorns of Sparklegrove Forest find ways to be brave, in this magical series from the creator of the bestselling Owl Diaries series!Pick a book. Grow a Reader!This series is part of Schola

America''s favorite series returns with a new look and a Netflix tv show.The truth about Stacey is that she has diabetes, a fact she keeps secret from everyone except her new friends in the Baby-sitte

Meet Rainbow Tinseltail and the unicorns of Sparklegrove Forest, in this magical series from the creator of the bestselling Owl Diaries series!Pick a book. Grow a Reader!This series is part of Scholas

Holling覺得自己卡在最糟的夾縫裡：學校裡，他要獨自留下來念莎士比亞；家裡，爸爸只在乎面子，完全不聽家人心聲。每個月都有新難題，每個星期三都讓他懊惱不已。但日子過著過著，他開始喜歡上莎士比亞的詞句，也開始看見Mrs. Baker真實的一面——甚至也開始懂得，如何保護想守護的人。Gary D. Schmidt 用輕柔幽默的筆觸描寫少年心事與時代背景交織的成長故事，溫和卻深刻，讀完令人回味不已。2008 Newbery Honor BookIn this Newbery Honor–winning novel, Gary D. Schmidt tells the witty and compelling story of a teenage boy who feels that fate has it in for him.Seventh grader Holling Hoodhood isn't happy. He is sure his new teacher, Mrs. Baker, hates his guts. Throughout the school year, Holling strives to get a handle on the Shakespeare plays Mrs. Baker assigns him to read on his own time, and to figure out the enigmatic Mrs. Baker. At home, Holling's domineering father is obsessed with his business image and disregards his family.As the Vietnam War turns lives upside down, Holling comes to admire and respect both Shakespeare and Mrs. Baker, who have more to offer him than he imagined. And when his family is on the verge of coming apart, he also discovers his loyalty to his sister,

Professor Volt's first time machine somehow made it to the present and must be escorted back in time as soon as possible, before it alters the course of history!

Next stop...The Magic School Bus heads to Antarctica to learn about glaciers! D.A. is more of a researcher than a storyteller, so she's naturally nervous when her parents sign her up to speak in front

After tragedy strikes their family, Emily and Navin move with their mother into the old, mysterious home of their great-grandfather. On their first night in the strange house, Emily and Navin's mom is

故事中的超級小兔是電玩世界中最會跑也最勇敢的角色，每本都有緊張刺激的任務要完成，超級小兔能闖關成功嗎？還是會被Game Over呢？Rabbit Boy is a super-fast and super brave, but he's also a video game character living in a video game world. What will happen when Sunny, the boy playing th game, loses each level? Will it be game over for Super Rabbit Boy and all his friends?#1 Game Over, Super Rabbit Boy!Uh-oh, Animal Town is in trouble! Meanie King Viking has created a dreaded robot army to spread No Fun across the land. On top of that, he has stolen the happiest and most fun animal ever, Singing Dog. There is only one person who can save the day -- Super Rabbit Boy! Super Rabbit Boy is super fast and super brave, but he's also a video game character living in a video game world. What will happen when Sunny, the boy playing the game, loses each level? Will it be game over for Super Rabbit Boy and all his friends?#2 Super Rabbit Boy Powers Up!Baddie King Viking is tired of always losing to hero Super Rabbit Boy. So he's gone to the Secret Lands to se

What if you woke up one morning and you had sprouted a tail overnight? What If You Had An Animal Tail? -- the next imaginative book in the What If You Had series -- explores what would happen if you l

Bo Dickinson is a girl with a wild reputation, a deadbeat dad, and a mama who's not exactly sober most of the time. Everyone in town knows the Dickinsons are a bad lot, but Bo doesn't care what anyone

I, Geronimo Stilton, was called to the Kingdom of Fantasy for the tenth time! A fairy princess had called me there. She needed my help: The most powerful and dangerous wizard in the realm wanted to capture her -- and conquer the entire kingdom!The wizard was hunting for special magical objects to increase his powers -- fairy dust to make him fly, the precious gold of the gnomes, the dazzling egg of fire, and more. It was up to me to foil his plans, with the help of magical friends new and old. Could we save the Kingdom of Fantasy?