Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

In this New York Times bestseller, updated for 2016, an award-winning journalist uses ten maps of crucial regions to explain the geo-political strategies of the world powers—“fans of geography, history, and politics (and maps) will be enthralled” (Fort Worth Star-Telegram).Maps have a mysterious hold over us. Whether ancient, crumbling parchments or generated by Google, maps tell us things we want to know, not only about our current location or where we are going but about the world in general. And yet, when it comes to geo-politics, much of what we are told is generated by analysts and other experts who have neglected to refer to a map of the place in question.All leaders of nations are constrained by geography. In “one of the best books about geopolitics” (The Evening Standard), now updated to include 2016 geopolitical developments, journalist Tim Marshall examines Russia, China, the US, Latin America, the Middle East, Africa, Europe, Japan, Korea, and Greenland and the Arctic—their

“An absolutely dazzling triumph…A singularly inventive collection” (Jewish Book Council) of linked stories set in a German-occupied town in Poland during World War II, where tales of myth and folklore

Soon to be a major motion picture starring Matthew McConaughey and Idris ElbaThe second volume in Stephen King’s #1 bestselling Dark Tower Series, The Drawing of the Three is an “epic in the making” (

Carnival in Venice, a time for masks and mystery and—sometimes—malice. When middle-aged American expatriate Tom, living in Paris, suggests to a group of friends that they gather in Venice for a mischi

At some point in nearly every marriage, a wife finds herself asking, What the @#!% is wrong with my husband?! In David Finch’s case, this turns out to be an apt question. Five years after he married K

Agenerational novel which opens memorably in a fur storage house in Los Angeles with its American protagonist as a boy trying on Marilyn Monroe’s coat. When he grows up, Stephen goes to O

W.B. Yeats's The Winding Stair and Other Poems was published in 1933 when Yeats was sixty-eight, ten years after he won the Nobel Prize and six years before his death in 1939. Yeats famously invoked

Tony Doerr's acclaimed debut story collection, now in a new edition from Scribner.

In the aftermath of Martin Luther King Jr.'s assassination, riots broke out in 110 cities across the country. For five days, Atlanta braced for chaos while preparing to host King's funeral. An unlike

An unquestioned masterpiece of the historian's art, and a towering landmark in the literature of the American Civil War. In Gettysburg to Appomattox, Douglas Southall Freeman concludes his monumenta

An striking new workabout the evolution of urban planning in America from acclaimed author Witold Rybczynski.

From the bestselling author and parenting expert Wendy Mogel comes an eagerly awaited new book on parenting teenagers.

The Weekly World News team uncovers the definitive and faux-tastic story of Bat Boy, from his hardscrabble origins in the caves of West Virginia to his global influence in the twenty-first century. G

Anita Diamant'sstory of four women, refugees from Nazi Europe, who find friendship, love, and salvation in a post-war British camp in Palestine.

In this fifth book in the Wine Country Mystery series, Lucie Montgomery journeys to Washington D.C., as she searches for a missing friend.

The story behind the bottle, First Big Crush is Eric Arnold's wild account of his year immersing himself in all things wine...and somehow not winding up in rehab. Never having held a meaningful job

Now in paperback, Audrey Niffenegger'sspectacularly compelling second novelset in andaround Highgate Cemetery in London.

Generation A is set in the near future in a world where bees are extinct, until five unconnected people all around the world— in the United States, Canada, France, New Zealand, and Sri Lanka

Goat Song is the story of a year in the life of a couple who abandoned their one-bedroom apartment in New York City to live on seventy-five acres in Vermont and raise Nubian goats. In poetic, reverent

After thirty years of training creatures both tame and wild, Karen Pryor, pioneer in the field of no-punishment animal training, presents what she knows about teaching animals and what they in turn ha

Nicola Monaghan grew up in Nottingham, England. A career in finance took her to New York, Paris, and Chicago, but she gave it up to pursue an MA in creative writing at Nottingham Trent University. Sh

Nicola Monaghan grew up in Nottingham, England. A career in finance took her to New York, Paris, and Chicago, but she gave it up to pursue an MA in creative writing at Nottingham Trent University. Sh

In this brave, beautiful, and deeply personal memoir, Laura Bush, one of our most beloved and private first ladies, tells her own extraordinary story.Born in the boom-and-bust oil town of Midla

Richard Snow's non-fiction account of America's role in the Battle of the Atlantic in WWII

Pulitzer Prize-winnerKai Bird'svivid memoir of an American childhoodspent in the midst of the Arab-Israeli conflict in Jerusalem and Saudia Arabia.

In David Goodwillie's thrilling debut, the lives of a young radical and a failed journalist intertwine in the wake of a botched terrorist bombing.

At age twenty-five, Michael Hastings arrived in Baghdad to cover the war in Iraq for Newsweek. He had at his disposal a little Hemingway romanticism and all the apparatus of a twenty-first-century re

Basharat Peer's powerful memoir about growing up in war-torn Kashmir.

In Judgment of Paris, George M. Taber masterfully chronicled the historic 1976 wine tasting when unknown California wines defeated top French ones, marking a major turning point in wine history. Now

Malalai Joya has been called "the bravest woman in Afghanistan." At a constitutional assembly in Kabul in 2003, she stood up and denounced her country's powerful NATO-backed warlords. She was twenty-

The Monster in the Box is the latest addition to Ruth Rendell's classic and beguiling Inspector Wexford series. In this new book, Rendell takes Inspector Wexford back to his days as a young policeman

There are 206 bones in the human body. Forensic anthropologists know them intimately, can read in them stories of brief or long lives, and use them to reconstruct every kind of violent end. The twelf

Ruby is the youngest child in the tightly knit Bronstein family, a sensitive, observant girl who looks up to her older brothers and is in awe of her stern but gentle father, a Holocaust survivor whos

Published for the first time as Ernest Hemingway intended, one of the great writer's most enduring works: his classic memoir of Paris in the 1920sPublished posthumously in 1964, A Moveable Feast rema

Karen Pryor has improved the lives of millions of animals. A celebrated pioneer in the field of nopunishment animal training, she introduced an innovative training system in her groundbreaking bestse

The Dollmaker was originally published in 1954 to immediate success and critical acclaim. In unadorned and powerful prose, Harriette Arnow tells the unforgettable and heartbreaking story of the Nevel

Rachel Kushner has written an astonishingly wise, ambitious, and riveting novel set in the American community in Cuba during the years leading up to Castro's revolution -- a place that was a paradise

In his third volume of memoir, Reynolds Price explores six crucial years of his life -- his departure from home in 1955 to spend three years as a student at Oxford University; then his return to Nort

In 2004 on Palm Island, an Aboriginal settlement in the "Deep North" of Australia, a thirty-six-year-old man named Cameron Doomadgee was arrested for swearing at a white police officer. Forty minutes

When Roshi Philip Kapleau returned to the United States in 1966, after thirteen years of training in Japan with two of the country's greatest masters of Zen, he "did not come home empty-handed -- he