Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

A daring and deeply moving novel set in Argentina in the time of the Generals--a time when the streets are empty at night, and people have trained themselves not to see. Richard Garay lives with his

Set in a world of extraordinary circumstances, filled with stunning visual imagery and unforgettable characters, The Dark Tower series is unlike anything you have ever read. Here is the penultimate in

The dazzling, award-winning debut in a series that delivers mystery, romance, suspense, and fascinating forensic detailWhen farmers cutting turf in an Irish peat bog make a grisly discovery -- the pe

In this dazzling and critically acclaimed debut collection, Mary Yukari Waters provides a rare glimpse into the heart and humanity of a society in the midst of immense change. These graceful, expertl

Colm Tóibín knows the languages of the outsider, the secret keeper, the gay man or woman. He knows the covert and overt language of homosexuality in literature. In Love in a Dark Time, he a

Originally published in 1978, this special twenty-fifth-anniversary edition of the National Book Award finalist includes an entirely new afterword in which the author considers the current state of k

In Living History, Hillary Rodham Clinton writes with candor, humor and passion about coming of age during a time of tumultuous social and political change in America and about the White House years.

The lives of middle-aged women struggling with jobs and family, friendship and romance, are captured to perfection in this collection of humorous and touching stories set in the contemporary Southwes

Yogi, a scrappy Jack Russell terrier, has a pain in the neck and hasn't walked for weeks.Nikita is a fifteen-year-old seal point Himalayan cat who has lost all interest in eating.And then there's Ang

In Mind Wide Open, Steven Johnson embarks on this path as his own test subject, participating in a battery of attention tests, learning to control video games by altering his brain waves, scanning hi

The first edition of W. B. Yeats's The Tower appeared in bookstores in London on Valentine's Day, 1928. His English publisher printed just 2,000 copies of this slender volume of twenty-one poems, pri

The most famous and important novel in South Africa's history, and an immediate worldwide bestseller when it was published in 1948, Alan Paton's impassioned novel about a black man's country under wh

Along with most of my fellow fliers, I believed that aviation had a brilliant future. Now we live, today, in our dreams of yesterday; and, living in those dreams, we dream again...." -- From The

In this ambitious follow-up to Achilles in Vietnam, Dr. Jonathan Shay uses the Odyssey, the story of a soldier's homecoming, to illuminate the pitfalls that trap many veterans on the road back to civ

First published in 1970, nine years after Ernest Hemingway's death, Islands in the Stream is the story of an artist and adventurer -- a man much like Hemingway himself. Rich with the uncanny sense of

Lean and controlled in their narration, abundant and moving in their effects, Maile Meloy's stories introduce a striking talent. Most are set in the modern American West, made vivid and unexpected in

The death of Ernest Hemingway in 1961 ended one of the most original and influential careers in American literature. His works have been translated into every major language, and the Nobel Prize awar

For more than twenty years, San Francisco's beloved Greens Restaurant has been in the avant garde of the cooking revolution in America. Greens has introduced millions of delighted fans to a sophistic

A prose poem is a poem written in prose rather than verse. But what does that really mean? Is it an indefinable hybrid? An anomaly in the history of poetry? Are the very words "prose poem" an oxymoro

John le Carre's classic novels deftly navigate readers through the intricate shadow worlds of international intrigue with unsurpassed skill and knowledge, and have earned him unprecedented worldwide acclaim. A lawyer from a London finance house is shot dead on a Turkish hillside by people with whom he thought he was in business. A children's magician in the English countryside is asked to explain the arrival of more than five million pounds sterling in his young daughter's modest trust. In Single & Single, le Carre masterfully establishes a sequence of events whose connections are mysterious, complex and compelling. He tells of corrupt liaisons between criminal elements in the new Russian states and the world of legitimate finance in the West. He also paints an intimate portrait of two families: one Russian, the other English; one trading illicit goods, the other laundering the profits; one betrayed by a son-in-law, the other betrayed, and redeemed, by a son.

In the lush countryside of 1950s Michigan, young Martin Dijksterhuis has everything he could ever want, living among his extended family and working in his family's orchard fields. Despite his mother

The state police of Troop D in rural Pennsylvania have kept a secret in Shed B out back of the barracks ever since 1979, when Troopers Ennis Rafferty and Curtis Wilcox answered a call from a gas stat

Since its inception in 1988, The Best American Poetry series has achieved brand-name status in the literary world as the preeminent showcase of each year's most important contributions to American poe

The story of a journalist and U.S. citizen who was murdered in San Francisco in 1984 reveals the intensity of the ongoing struggle between China and Taiwan and describes the United States' role in the

Throughout his long life, William Butler Yeats -- Irish writer and premier lyric poet in English in this century -- produced important works in every literary genre, works of astonishing range, energ

A young doctor describes her practice in an inner-city health clinic in Boston, detailing her remarkable patients and their families, as well as their struggles to overcome the physical and social pro

When Tarzan of the Apes was published in The All-Story in 1912, Edgar Rice Burroughs was just another would-be writer struggling to support himself and his family by penning adventure stories for read

In this classic, John le Carré's third novel and the first to earn him international acclaim, he created a world unlike any previously experienced in suspense fiction. With unsurpassed knowledge culle

Larry McMurtry returns to the Old West in a fast-moving, comic tale about a woman determined to conquer anything that stands in the way of an ultimate confrontation with her wayward husband. In his f

In 1981 David Quammen began what might be every freelance writer's dream: a monthly column for Outside magazine in which he was given free rein to write about anything that interested him in the natu

Though reticent in public, George Bush has openly shared his private thoughts in correspondence throughout his life. Fortunately, since the former president does not plan to write his autobiography,

Frank McCourt returned to America when he was nineteen. For many years, he was an English teacher at Stuyvesant High School in New York City. The sequel to Angela's Ashes, 'Tis, will be published in

Historical and international in scope, a unique anthology traces the course of literary journalism and nonfiction prose from its origins in the eighteenth century to today, from Daniel Defoe to Joseph

A towering landmark in Civil War literature, long considered one of the great masterpieces of military history -- now available in a one-volume abridgment.Lee's Lieutenants: A Study in Command is the

Charles Johnson, author of Dreamer, received the National Book Award for Middle Passage in 1990. Currently the Pollock Professor of English at the University of Washington, he lives in Seattle with h

0ne of the most feisty, spellbinding and engaging heroines in modern fiction captures the essence of her own life in this contemporary American odyssey born of red-clay land and small-town people. We

In the fall of 1948, Ernest Hemingway made his first extended visit to Italy in thirty years. His reacquaintance with Venice, a city he loved, provided the inspiration for Across the River and into t

A naturalist/scientist introduces unusual creatures and their surprising habits, in a study that emphasizes the wealth of variety in the animal kingdom rather than the "freakishness" of the uncommon

Alice Andrews is living in Manhattan, working as a reporter in Newark, and trying to forget the smooth-talking investment banker she thought was Mr. Right. When she meets Jack Russworm, a handsome, H

From its inception in California in 1974 to its highly acclaimed critical success at Joseph Papp's Public Theater and on Broadway, the Obie Award-winning for colored girls who have considered suicide