The statistics profession is at a unique point in history. The need for valid statistical tools is greater than ever; data sets are massive, often measuring hundreds of thousands of measurements for a
This textbook for graduate students in statistics, data science, and public health deals with the practical challenges that come with big, complex, and dynamic data. It presents a scientific roadmap t
?This book is the result of a joint venture between Professor Akio Kawauchi, Osaka City University, well-known for his research in knot theory, and the Osaka study group of mathematics education, foun
We present an in-depth description of resistance to targeted therapies in breast cancer. Targeted therapies discussed here include those used to treat ER+ or Her2+ breast cancers (i.e., Tamoxifen or t
This book discusses the latest molecular targeted therapy of lung cancer including its evaluation and future directions. It clearly illustrates the initial dramatic effectiveness of molecular targeted
This volume examines recent trends and future opportunitiesin controlled and targeted drug delivery. The emphasis is onthe biological basis of drug targeting and on the use ofprotein engineering and
This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the
This book serves as a comprehensive guide to the rapidly evolving field of molecular neuropathology of nervous system tumors, as well as the underlying biology and emerging molecular targeted therapie
This book provides an unprecedented overview of "Targeted Therapies" for acute myeloid leukemias. It aims at an almost comprehensive coverage of the diverse therapeutic strategies th
Guide to Targeted Therapies: EGFR Mutations in NSCLC is a speedy and up-to-date review, which discusses EGFR mutations, testing methods and technology, current and emerging therapies, and resources th
Targeted intraoperative radiotherapy is a major advance in the management of cancer patients and has been attracting massive interest worldwide following publication of the results of an important ran
This volume provides information related to the difficulties in treating cancers through targeted drug delivery. It examines our current understanding of cancer biology as well as potential technologi
Janet Lau's thesis describes her studies into the use of phthalocyanine-based photosensitizers in combined chemo- and photodynamic therapy (PDT) and targeted PDT. In order to carry out this study, Lau
Targeted Therapies highlights changes in the signaling network in response to inhibition of a signaling event. The text illustrates how a mechanistic understanding of the signaling network in cancer i
This monograph is the first in the new area of targeted nonlinear energy transfer in mechanical and structural systems. This concept was initially discovered by the two leading authors in 1999, and w
At last! The book for anyone who writes regulatory documents or wishes to learn more about writing regulatory documents for the biopharmaceutical industry. Targeted Regulatory Writing Techniques: Clin
In September 2005 an International Meeting on "Targeted Therapies in Cancer: Myth or Reality" was held in Milan. This successful Meeting was intended to represent a forum for scientists and clinician
This volume is unique in reporting on strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors,
This volume covers the most important areas of glioblastoma – surgical resection, molecular pathology, targeted therapies, cancer stem cells, the role of DNA methylation, targeted sequencing for perso
This book focuses on developing methods for constructing learning paths in terms of “learning resources” (learning contents), “learning approaches” (learning method), and “learning quality” (learning
This book reports the results of a three-year research program funded by the National Science Foundation which targeted students and teachers from four Detroit high schools in order for them to learn,
This book will be a guide to understanding resistance against targeted therapeutic approaches for cancer using immunotoxins. It contains a detailed review of the history and development of targeted th
This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to revi
This book serves as an introduction to targeted genome editing, beginning with the background of this rapidly developing field and methods for generation of engineered nucleases. Applications of genom
Existing international law is capable to govern the “war on terror” also in the aftermath of September 11, 2001. The standards generally applicable to targeted killings are those of human rights law.
This book explores how traditional institutions of education are affected by the current discourse and practices of ‘learning’; and more specifically, how the evolution towards so-called ‘learning env
The book covers tools in the study of online social networks such as machine learning techniques, clustering, and deep learning. A variety of theoretical aspects, application domains, and case studies
Reinforcement Learning for Optimal Feedback Control develops model-based and data-driven reinforcement learning methods for solving optimal control problems in nonlinear deterministic dynamical system
This volume sheds light on debates about personalised learning in teacher education by exploring the popular emergence of personalising learning in education and hence its significance in teacher educ
‘Behavioral Neuroscience of Learning and Memory’ brings together the opinions and expertise of some of the world’s foremost neuroscientists in the field of learning and memory research. The volume pro
This integrated collection of perspectives on the spaces of teaching and learning uses ‘learning space’ to place educational practice in context. It considers the complex relationships involved in the
This book deals with advanced methods for adaptive phase I dose-finding clinical trials for combination of two agents and molecularly targeted agents (MTAs) in oncology. It provides not only methodolo
This book highlights electromagnetic actuation (EMA) and sensing systems for a broad range of applications including targeted drug delivery, drug-release-rate control, catheterization, intravitreal ne
This book develops a machine-learning framework for predicting economic growth. It can also be considered as a primer for using machine learning (also known as data mining or data analytics) to answer
This book analyzes the nature and requirements of workplace e-learning based on relevant theories such as adult learning, community of practice, organizational learning, and the systems thinking. By i
This book explores the theoretical foundations of gamification in learning and education. It has become increasingly difficult to engage and motivate students. Gamification not only makes learning int
This is the first book to connect the concepts of active learning and deep learning, and to delineate theory and practice through collaboration between scholars in higher education from three countrie
This book examines the most novel and state-of-the-art applications of biomaterials, with chapters that exemplify approaches with targeted drug delivery, diabetes, neurodegenerative diseases and crani
In this unique title, the full range of chronic respiratory conditions and their association with psychiatric comorbidities are explored and targeted management options are outlined. Indeed recent stu
This book offers several insights into cross-cultural and multilingual learning, drawing upon recent research within two main areas: Language Studies and Multilingual Language Learning/Teaching. It pl
