Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

In this delightful book for young children, machines rattle and bang, whirr and purr, scoot along, clutter and mutter. Machines are everywhere - from the kitchen to outer space! Illustrated with great

Down in the jungle where nobody goes, there is something very exciting going on! If you are very quiet, you will see lot

The construction industry is now facing unprecedented challenges resulting from the advances in information technology and networking through the web. Procurement paradigm of the construction industry

All the official reports say they are dead-extinct since the late ’80s, when a fed named Arkeley nailed the last vampire in a fight that nearly killed him. But the evidence proves otherwise.When a sta

IN 1974, AFTER SUFFERING rejections from seven major publishers, The Chocolate War made its debut. An uncompromising portrait of conformity and corruption, it quickly became a bestselling—and provocat

The middle ages, the age of Charlemagne, Chaucer and Dante, had an indelible effect on European culture. In Search of the Hol

IN THE OLD DAYS THERE WERE SONGS Something is bothering Russel Susskit. He hates waking up to the sound of his father's coughing, the smell of diesel oil, the noise of snow machines starting up. O

Join in the fun with this hilarious read-aloud story featuring the pesky, pestering Pigeon!It's getting late and the bus driver is going to brush his teeth and get ready for bed. Will you do him a fav

Stink's class is going on a field trip to the Gross-Me-Out exhibition at the science museum! There, he discovers that his nose has amazing sniffing abilities. Before long, he's set to go toe-to-toe in

“A literary landmark. Gellhorn’s prose . . . is at its finest in the letter form.”—Francine du Plessix Gray, The New York Times Book ReviewMartha Gellhorn’s reporting career brought her to the front lines of virtually every significant conflict from the Spanish Civil War to the end of the cold war. While Gellhorn’s wartime dispatches rank among the best of the century, her personal letters are their equal: as vivid and fascinating as her reporting was trenchant. Gellhorn’s correspondence introduces us to the woman behind the often inscrutable journalist, chronicling her friendships with twentieth-century luminaries as well as her tempestuous marriage to Ernest Hemingway. Caroline Moorehead, Gellhorn’s critically acclaimed biographer, was granted exclusive access to the letters. This expertly edited volume contextualizes Gellhorn’s correspondence within the arc of her entire life; the result is an intimate portrait of one of the most accomplished women of modern times. A distinguished b

Haunted by scandal and secrets, Lillian Baptiste fled Dominica when she was fourteen after discovering she was the daughter of Iris, the half-crazy woman whose life was told of in chante mas songs sun

受到《怪奇物語》熱潮狂推、熱賣超過 60 年的不敗經典紐伯瑞金牌得主之作、入選《TIME》世紀百大奇幻小說，更是迪士尼電影的靈感來源。跟著勇敢的女孩踏上穿越時空、橫越宇宙的冒險旅程，一讀就停不下來，保證讓你愛上這部經典。《A Wrinkle in Time》是經典得獎科幻小說「時光五部曲」的第一集，描述看似平凡又有點叛逆的女孩 Meg，為了尋找失蹤的科學家父親，和弟弟 Charles Wallace、同學 Calvin 一起被三位神祕「Mrs. W」帶往宇宙深處展開冒險。途中他們穿越時空、造訪奇異星球，必須對抗象徵極權與同化的黑暗力量...As seen on Stranger Things, discover the ground-breaking, bestselling science fiction and fantasy classic that has delighted readers for over 60 years!NEWBERY MEDAL WINNER TIME MAGAZINE’S 100 BEST FANTASY BOOKS OF ALL TIME NOW A MAJOR MOTION PICTURE FROM DISNEY"A Wrinkle in Time is one of my favorite books of all time. I've read it so often, I know it by heart." —Meg CabotThis audiobook includes an introduction read by the film director Ava DuVernay, a foreword read by the author, and an afterword read by Madeleine L’Engle’s granddaughter Charlotte Jones Voiklis.Late one night, three otherworldly creatures appear and sweep Meg Murry, her brother Charles Wallace, and their friend Calvin O'Keefe away on a mission to sav

It is November. When Meg comes home from school, Charles Wallace tells her he saw dragons in the twin’s vegetable garden. That night Meg, Calvin and C.W. go to the vegetable garden to meet the Teache

An amusing, original story with easy reading text, speech bubbles and delightful illustrations on every page.The eccentric Mr. Puff lives next door to Sam in a house full of interesting things - inclu

Part of the Longman Library of Primary Sources in Philosophy,” this first volume of Schopenhauer's The World as Will and Presentation is framed by a pedagogical structure designed to make this important work of philosophy more accessible and meaningful for readers. A General Introduction includes the work's historical context, a discussion of historical influences, and biographical information on Arthur Schopenhauer. Annotations and notes from the editor clarify difficult passages for greater understanding, and a bibliography gives the reader additional resources for further study.

Animals and young children enjoy the same types of foods, including oats, oranges, and fish, in a book with pictures hidden beneath the flaps.

Babies will love lifting the flaps in this delightful board book to find out all about themselves! Focusing on different aspects of babies' features, this book encourages interaction and discussion. D

Animals and young children feel the same emotions, including shy, frightened, excited, and grumpy, in a book with pictures hidden beneath the flaps.

Infernal Affairs has received journalistic, popular and corporate notice but little vigorous critical attention. In this book, Gina Marchetti explores the way this example of Hong Kong's cinematic ecl

Gerald is careful. Piggie is not. Piggie cannot help smiling. Gerald can. Gerald worries so that Piggie does not have to. Gerald and Piggie are best friends. In My Friend is Sa

Penderwick姊妹們沒想到這年暑假竟能住進風景如畫的Arundel莊園。姊妹四人各有個性，卻在這片神祕又充滿驚喜的土地上一同展開屬於她們的冒險：野餐、藏寶、兔子、薑餅，還有最重要的新朋友Jeffrey。然而，莊園主人的母親Mrs. Tifton顯然不歡迎這段友情的滋長……這是一本節奏悠緩卻處處有趣的小說，帶著古典童書的氣質，書寫一段關於友情、家庭與探索的夏日回憶，適合喜歡《小婦人》《安妮》系列的讀者細細品味。This summer the Penderwick sisters have a wonderful surprise: a holiday on the grounds of a beautiful estate called Arundel. Soon they are busy discovering the summertime magic of Arundel's sprawling gardens, treasure-filled attic, tame rabbits, and the cook who makes the best gingerbread in Massachusetts. But the best discovery of all is Jeffrey Tifton, son of Arundel's owner, who quickly proves to be the perfect companion for their adventures. The icy-hearted Mrs. Tifton is not as pleased with the Penderwicks as Jeffrey is, though, and warns the new friends to stay out of trouble. Which, of course, they will — won't they? One thing's for sure: it will be a summer the Penderwicks will never forget. Deliciously nostalgic and quaintly witty, this is a story as breezy and carefree a

The Society of Captives, first published in 1958, is a classic of modern criminology and one of the most important books ever written about prison.Gresham Sykes wrote the book at the height of the Col

Low-life writer and unrepentant alcoholic Henry Chinaski was born to survive. After decades of slacking off at low-paying dead-end jobs, blowing his cash on booze and women, and scrimping by in flea-b

Charlie Eggleston is the biggest liar in town. When he finds himself at Mr. Elives' magic shop, his eyes light upon the skull. He steals it, and it puts him under some sort of spell: 

Bouncy illustrations, innovative die cutting and popular rhymes make Books with Holes a must for every child. Available in three formats, suitable for babies, toddlers, pre-schoolers and the nursery o

這是一本專為幼兒設計的精裝厚頁書，以彩虹小仙子為主角，透過押韻文字帶孩子認識顏色。每一頁都有閃耀的全像雷射燙箔，小仙子們穿著不同顏色的服裝，忙著為即將到來的仙子舞會做準備。節奏感十足的句子搭配亮眼視覺效果，讓孩子在翻閱與朗讀中，自然學習顏色，也沉浸在充滿魔法與想像力的童話世界。A fun way to learn colors--with rhyming text and holographic foil on every spread!"Fairy orange, fairy blue, fastening up their fairy shoes.""Rainbow fairies one and all, ready for the fairy ball!"You are invited to the fairy ball! This sturdy casebound board book teaches colors and features rhyming text and holographic foil on every spread! Glittering fairies in all the colors of the rainbow prepare to greet the fairy queen. Join the fun!

Merlin the Magician will not eat or sleep or speak to anyone in Camelot. What can be done? The enchantress Morgan knows who to askfor help: young Jack and Annie of Frog Creek, Pennsylvania! The brothe

It's Poetry Month! And Ms. Coco, who runs the gifted and talented program, is poetry crazy! She cries when she sees a sunset! She thinks boys should have feelings! She talks in rhyme! All the time! Wi

The Ready-Set-Learn series has just what parents want: fun-filled activities to give their children a head start on learning the basic skills needed for success in school. The 7" x 9" size is just rig

The Ready-Set-Learn series has just what parents want: fun-filled activities to give their children a head start on learning the basic skills needed for success in school. The 7" x 9" size is just rig

The Ready-Set-Learn series has just what parents want: fun-filled activities to give their children a head start on learning the basic skills needed for success in school. The 7" x 9" size is just rig

The Ready-Set-Learn series has just what parents want: fun-filled activities to give their children a head start on learning the basic skills needed for success in school. The 7" x 9" size is just rig

After being called a rocket scientist by Mr. Rogers after washing his reading glasses in the dishwasher, housekeeper Amelia Bedelia wreaks havoc when she volunteers to be a judge at the school science

In the past thirty years, historians have broadened the scope of their discipline to include many previously neglected topics and perspectives. They have chronicled language, madness, gender, and sexu

This Willow Creek Resources six-session evangelism course for churches and groups of all sizes is designed to equip believers for effective evangelism by showing them how they can share the gospel in

Timothy Pope has a brand new telescope and he's testing it out at the park. Children will delight in peeping through the die-cut holes and guessing what Tim has spotted. Is that really a shark he can

Lost in an Australian rainforest, Andrew, Judy, and Thudd the robot, who are still the size of insects, must evade Rhinoceros beetles, tarantulas, flesh-eating plants, and a host of other threats as they make their way toward the village where Uncle Al will meet them.Lost in an Australian rainforest, Andrew, Judy, and Thudd the robot, who are still the size of insects, must evade rhinoceros beetles, tarantulas, flesh-eating plants, and a host of other threats as they make their way toward the village where Uncle Al will meet them.

From Kevin Brockmeier, one of this generation's most inventive young writers, comes a striking new novel about death, life, and the mysterious place in between. The City is inhabited by those who hav

The phenomenal classic that has changed the lives of millions of people around the globe What are you afraid of? Public speaking; asserting yourself; making decisions; being alone; intimacy; changing jobs; interviews; going back to school; ageing; ill health; driving; dating; ending a relationship; losing a loved one; becoming a parent; leaving home, failure, believing in yourself... Internationally renowned author Susan Jeffers has helped millions of people overcome their fears and heal the pain in their lives with her simple but profound advice. Whatever your anxieties, Feel The Fear And Do It Anyway® will give you the insight and tools to vastly improve your ability to handle any given situation.You will learn to live your life the way you want - so you can move from a place of pain, paralysis, depression and indecision to one of power, energy, enthusiasm and action. An empowering and life-affirming book, Feel the Fear and Do It Anyway will help you triumph over your fears and move

Bendemolena the kitten lives in a noisy house, so she puts a shiny pot on her head and everything goes quiet. Hooray! But what happens when Mother Cat gives her messages to take back to her brothers a