Adaptive Filtering

The Constructive Mind is an integrative study of the psychologist Frederic Bartlett's (1886–1969) life, work and legacy. Bartlett is most famous for the idea that remembering is constructive and for the concept of schema; for him, 'constructive' meant that human beings are future-oriented and flexibly adaptive to new circumstances. This book shows how his notion of construction is also central to understanding social psychology and cultural dynamics, as well as other psychological processes such as perceiving, imagining and thinking. Wagoner contextualises the development of Bartlett's key ideas in relation to his predecessors and contemporaries. Furthermore, he applies Bartlett's constructive analysis of cultural transmission in order to chart how his ideas were appropriated and transformed by others that followed. As such this book can also be read as a case study in the continuous reconstruction of ideas in science.

This Element analyzes the various forms that design arguments for the existence of God can take, but the main focus is on two such arguments. The first concerns the complex adaptive features that organisms have. Creationists who advance this argument contend that evolution by natural selection cannot be the right explanation. The second design argument - the argument from fine-tuning - begins with the fact that life could not exist in our universe if the constants found in the laws of physics had values that differed more than a little from their actual values. Since probability is the main analytical tool used, the Element provides a primer on probability theory.

Spinoza's Political Psychology advances a novel, comprehensive interpretation of Spinoza's political writings, exploring how his analysis of psychology informs his arguments for democracy and toleration. Justin Steinberg shows how Spinoza's political method resembles the Renaissance civic humanism in its view of governance as an adaptive craft that requires psychological attunement. He examines the ways that Spinoza deploys this realist method in the service of empowerment, suggesting that the state can affectively reorient and thereby liberate its citizens, but only if it attends to their actual motivational and epistemic capacities. His book will interest a range of readers in Spinoza studies and the history of political thought, as well as readers working in contemporary political theory.

How, practically speaking, is the Chinese polity - as immense and fissured as it has now become - actually being governed today? Some analysts highlight signs of 'progress' in the direction of more liberal, open, and responsive rule. Others dwell instead on the many remaining 'obstacles' to a hoped-for democratic transition. Drawing together cutting-edge research from an international panel of experts, this volume argues that both those approaches rest upon too starkly drawn distinctions between democratic and non-democratic 'regime types', and concentrate too narrowly on institutions as opposed to practices. The prevailing analytical focus on adaptive and resilient authoritarianism - a neo-institutionalist concept - fails to capture what are often cross-cutting currents in ongoing processes of political change. Illuminating a vibrant repertoire of power practices employed in governing China today, these authors advance instead a more fluid, open-ended conceptual approach that privileg

Discover new concepts in cardiovascular and hemodynamic functionality during pregnancy, with international experts in feto-maternal medicine. During the early stages of pregnancy, the maternal heart and circulation are subject to major gestational adaptive changes that allow for a normal course and outcome for both mother and baby. Any disruption to these processes can precipitate the onset of severe maternal and fetal complications such as preeclampsia, or intrauterine growth restriction. This invaluable reference work provides a comprehensive discussion of each aspect of the circulation. With a focus on the physiologic and pathophysiologic aspects of maternal cardiovascular function, this guide supports non-invasive assessment, management and prevention techniques for cardiovascular disease, for all stages of fetal and neonatal life. This text supports researchers and specialists in maternal-fetal medicine, whilst providing a key grounding in the topic, for trainees wishing to be at

The central insight of Darwin's Origin of Species is that evolution is an ecological phenomenon, arising from the activities of organisms in the 'struggle for life'. By contrast, the Modern Synthesis theory of evolution, which rose to prominence in the twentieth century, presents evolution as a fundamentally molecular phenomenon, occurring in populations of sub-organismal entities - genes. After nearly a century of success, the Modern Synthesis theory is now being challenged by empirical advances in the study of organismal development and inheritance. In this important study, D. M. Walsh shows that the principal defect of the Modern Synthesis resides in its rejection of Darwin's organismal perspective, and argues for 'situated Darwinism': an alternative, organism-centred conception of evolution that prioritises organisms as adaptive agents. His book will be of interest to scholars and advanced students of evolutionary biology and the philosophy of biology.

This volume presents eighteen case studies of natural disasters from Australia, Europe, North America and developing countries. By comparing the impacts, it seeks to identify what moves people to adapt, which adaptive activities succeed and which fail, and the underlying reasons, and the factors that determine when adaptation is required and when simply bearing the impact may be the more appropriate response. Much has been written about the theory of adaptation and high-level, especially international, policy responses to climate change. This book aims to inform actual adaptation practice - what works, what does not, and why. It explores some of the lessons we can learn from past disasters and the adaptation that takes place after the event in preparation for the next. This volume will be especially useful for researchers and decision makers in policy and government concerned with climate change adaptation, emergency management, disaster risk reduction, environmental policy and plannin

China stands as a major “Red Swan” challenge to the social sciences. The resilience of the Communist party-state, in combination with a rapidly expanding and internationally competitive economy, challenges conventional models of economic development and political change. This book focuses on crucial governmental action programs and examines the manner in which they were developed, formulated, implemented, adjusted, and revised. It finds that Chinese policy making has been driven by a distinctive political methodology—an unusual combination of long-term national agendas with versatile local policy experimentation—that serves as an effective mechanism for policy innovation and correction, and thus provides strong adaptive capabilities in a perpetually shifting economic, technological and international context. ~~~~~~~~~~~~~~~ An original and persuasive book by one of the leading scholars of China’s policy-making process. The paradox of China’s successful market reforms is that they wer

Developed by experts in trauma psychiatry and psychology and grounded in adolescent developmental theory, this is a modular, assessment-driven treatment that addresses the needs of adolescents facing trauma, bereavement, and accompanying developmental disruption. Created by the developers of the University of California, Los Angeles PTSD Reaction Index© and the Persistent Complex Bereavement Disorder Checklist, the book links clinicians with cutting-edge research in traumatic stress and bereavement, as well as ongoing training opportunities. This innovative guide offers teen-friendly coping skills, handouts, and specialized therapeutic exercises to reduce distress and promote adaptive developmental progression. Sessions can be flexibly tailored for group or individual treatment modalities; school-based, community mental health, or private practice settings; and different timeframes and specific client needs. Drawing on multidimensional grief theory, it offers a valuable toolkit for psy

How, practically speaking, is the Chinese polity - as immense and fissured as it has now become - actually being governed today? Some analysts highlight signs of 'progress' in the direction of more liberal, open, and responsive rule. Others dwell instead on the many remaining 'obstacles' to a hoped-for democratic transition. Drawing together cutting-edge research from an international panel of experts, this volume argues that both those approaches rest upon too starkly drawn distinctions between democratic and non-democratic 'regime types', and concentrate too narrowly on institutions as opposed to practices. The prevailing analytical focus on adaptive and resilient authoritarianism - a neo-institutionalist concept - fails to capture what are often cross-cutting currents in ongoing processes of political change. Illuminating a vibrant repertoire of power practices employed in governing China today, these authors advance instead a more fluid, open-ended conceptual approach that privileg

Recent developments in behavioural neuroscience and genomics are providing exciting new tools for understanding mammalian evolution. Drawing on a range of disciplines including genomic reprogramming, immunology, genomic imprinting, placentation and brain development, this book examines the leading role played by the mother's genome and epigenome in the successful evolutionary progression of humans from ancestral mammals. Keverne begins by discussing the historic context of the perceived dominance of males and the patriline, before arguing that it is instead the matriline that exerts the dominant influence in shaping the evolution of our brain development and behaviour, especially the co-adaptive development of brain and placenta. Presenting a balanced outlook on the development of sex differences and an alternative to traditional views, Beyond Sex Differences will be of interest to anyone studying and researching mother and infant development.

This second edition provides a comprehensive and scientific approach to evaluating ship resistance and propulsion. Written by experts in the field, it includes the latest developments in CFD, experimental techniques and guidance for the practical estimation of ship propulsive power. It addresses improvements in energy efficiency and reduced emissions, and the introduction of the Energy Efficiency Design Index (EEDI). Descriptions have now been included of pump jets, rim driven propulsors, shape adaptive foils, propeller noise and dynamic positioning. Trial procedures have been updated, and preliminary estimates of power for hydrofoil craft, submarines and AUVs are incorporated. Standard series data for hull resistance and propeller performance are included, enabling practitioners to make ship power predictions based on material and data within the book. Numerous fully worked examples illustrate applications for most ship and small craft types, making this book ideal for practising engi

This path-breaking book argues that practices of the sacred are constitutive of modern secular politics. Following a tradition of enquiry in anthropology and political theory, it examines how limit situations shape the political imagination and collective identity. As an experiential and cultural fact, the sacred emerges within, and simultaneously transcends, transgressive dynamics such as revolutions, wars or globalisation. Rather than conceive the sacred as a religious doctrine or a metaphysical belief, Wydra examines its adaptive functions as origins, truths and order which are historically contingent across time and transformative of political aspirations. He suggests that the brokenness of political reality is a permanent condition of humanity, which will continue to produce quests for the sacred, and transcendental political frames. Working in the spirit of the genealogical mode of enquiry, this book examines the secular sources of political theologies, the democratic sacred, the

大氣湍流的隨機擾動嚴重地影響光學系統的成像性能，本書對湍流效應的自適應光學(Adaptive Optics, AO)圖像復原問題進行了研究和探討。本書主要從兩個方面研究自適應光學圖像復原問題：一是研究自適應光學系統的構成及光學成像原理，提出了自適應光學系統改進及仿真，實現自適應光學圖像波前畸變的即時補償或校正；二是研究經AO校正後的自適應光學圖像復原理論及演算法。主要內容包括湍流對成像影響的分析與

Astronomy is an observational science, renewed and even revolutionized by new developments in instrumentation. With the resulting growth of multiwavelength investigation as an engine of discovery, it is increasingly important for astronomers to understand the underlying physical principles and operational characteristics for a broad range of instruments. This comprehensive text is ideal for graduate students, active researchers and instrument developers. It is a thorough review of how astronomers obtain their data, covering current approaches to astronomical measurements from radio to gamma rays. The focus is on current technology rather than the history of the field, allowing each topic to be discussed in depth. Areas covered include telescopes, detectors, photometry, spectroscopy, adaptive optics and high-contrast imaging, millimeter-wave and radio receivers, radio and optical/infrared interferometry, and X-ray and gamma-ray astronomy, all at a level that bridges the gap between the

The Constructive Mind is an integrative study of the psychologist Frederic Bartlett's (1886–1969) life, work and legacy. Bartlett is most famous for the idea that remembering is constructive and for the concept of schema; for him, 'constructive' meant that human beings are future-oriented and flexibly adaptive to new circumstances. This book shows how his notion of construction is also central to understanding social psychology and cultural dynamics, as well as other psychological processes such as perceiving, imagining and thinking. Wagoner contextualises the development of Bartlett's key ideas in relation to his predecessors and contemporaries. Furthermore, he applies Bartlett's constructive analysis of cultural transmission in order to chart how his ideas were appropriated and transformed by others that followed. As such this book can also be read as a case study in the continuous reconstruction of ideas in science.

The second edition of this popular text provides undergraduates with a quantitative yet accessible introduction to the physical principles underlying the collection and analysis of observational data in contemporary optical and infrared astronomy. The text clearly links recent developments in ground- and space-based telescopes, observatory and instrument design, adaptive optics, and detector technologies to the more modest telescopes and detectors that students may use themselves. Beginning with reviews of the most relevant physical concepts and an introduction to elementary statistics, students are given the firm theoretical foundation they need. New topics, including an expanded treatment of spectroscopy, Gaia, the Large Synoptic Survey Telescope, and photometry at large redshifts bring the text up to date. Historical development of topics and quotations emphasize that astronomy is both a scientific and a human endeavour, while extensive end-of-chapter exercises facilitate the studen

How does behaviour affect biological invasions? Can it explain why some animals are such successful invaders? With contributions from experts in the field, and covering a broad range of animals, this book examines the role of behaviour in biological invasions from the point of view of both invaders and native species. The chapters cover theoretical aspects, particularly relevant behaviours and well-documented case studies, showing that behaviour is critical to the success, and ecological and socio-economic impact, of invasive species. Its insights suggest methods to prevent and mitigate those impacts, and offer unique opportunities to understand the adaptive role of behaviour. Offering a comprehensive overview of current understanding on the subject, the book is intended for biological invasion researchers and behavioural ecologists, as well as ecologists and evolutionary biologists interested in how organisms deal with anthropogenic environmental changes such as climate change and hab

While the environmental performance of most ASEAN member states is above the world average, ASEAN nations will continue to face growing environmental challenges due to pressures exerted on them such as population growth, urbanization and industrialization. The authors of this book look at how the member states of ASEAN employ law as a means of regional integration within the context of environmental conservation. While the goal of new laws is to implement sustainable development, it continues to be an ongoing adaptive process, since clear and immediate answers to environmental challenges are rarely available. Readers of this book will gain a clear idea of the evolving cooperation for sustainability within ASEAN at regional and global levels, and the areas of focus for the future. The book will be of interest to policy and decision makers, as well as environmental organizations and academics in the field.

安康*的《中国农产品蔬菜批发市场的性质与变迁研究--基于CAS和主观博弈契合》尝试性地提出了复杂适应性系统(Complex Adaptive System，简称CAS)和主观博弈契合的理论框架，从宏观和微观两个层次上对市场的性质进行新释义，进而从整体和个体两个层次上对我国农产品蔬菜批发市场的性质和变迁进行了理论透视，并选用我国东部和西部两个有着代表意义的案例对理论进行检验。本书通过对本质的分析，来挖掘现象产生的深层次原因，从而在理论层面上给出政策意蕴。

In nonparametric and high-dimensional statistical models, the classical Gauss-Fisher-Le Cam theory of the optimality of maximum likelihood estimators and Bayesian posterior inference does not apply, and new foundations and ideas have been developed in the past several decades. This book gives a coherent account of the statistical theory in infinite-dimensional parameter spaces. The mathematical foundations include self-contained 'mini-courses' on the theory of Gaussian and empirical processes, on approximation and wavelet theory, and on the basic theory of function spaces. The theory of statistical inference in such models - hypothesis testing, estimation and confidence sets - is then presented within the minimax paradigm of decision theory. This includes the basic theory of convolution kernel and projection estimation, but also Bayesian nonparametrics and nonparametric maximum likelihood estimation. In the final chapter, the theory of adaptive inference in nonparametric models is deve

Designing algorithms to recommend items such as news articles and movies to users is a challenging task in numerous web applications. The crux of the problem is to rank items based on users' responses to different items to optimize for multiple objectives. Major technical challenges are high dimensional prediction with sparse data and constructing high dimensional sequential designs to collect data for user modeling and system design. This comprehensive treatment of the statistical issues that arise in recommender systems includes detailed, in-depth discussions of current state-of-the-art methods such as adaptive sequential designs (multi-armed bandit methods), bilinear random-effects models (matrix factorization) and scalable model fitting using modern computing paradigms like MapReduce. The authors draw upon their vast experience working with such large-scale systems at Yahoo! and LinkedIn, and bridge the gap between theory and practice by illustrating complex concepts with examples

The central insight of Darwin's Origin of Species is that evolution is an ecological phenomenon, arising from the activities of organisms in the 'struggle for life'. By contrast, the Modern Synthesis theory of evolution, which rose to prominence in the twentieth century, presents evolution as a fundamentally molecular phenomenon, occurring in populations of sub-organismal entities - genes. After nearly a century of success, the Modern Synthesis theory is now being challenged by empirical advances in the study of organismal development and inheritance. In this important study, D. M. Walsh shows that the principal defect of the Modern Synthesis resides in its rejection of Darwin's organismal perspective, and argues for 'situated Darwinism': an alternative, organism-centred conception of evolution that prioritises organisms as adaptive agents. His book will be of interest to scholars and advanced students of evolutionary biology and the philosophy of biology.

This path-breaking book argues that practices of the sacred are constitutive of modern secular politics. Following a tradition of enquiry in anthropology and political theory, it examines how limit situations shape the political imagination and collective identity. As an experiential and cultural fact, the sacred emerges within, and simultaneously transcends, transgressive dynamics such as revolutions, wars or globalisation. Rather than conceive the sacred as a religious doctrine or a metaphysical belief, Wydra examines its adaptive functions as origins, truths and order which are historically contingent across time and transformative of political aspirations. He suggests that the brokenness of political reality is a permanent condition of humanity, which will continue to produce quests for the sacred, and transcendental political frames. Working in the spirit of the genealogical mode of enquiry, this book examines the secular sources of political theologies, the democratic sacred, the

As both the societies and the world in which we live face increasingly rapid and turbulent changes, the concept of resilience has become an active and important research area. Reflecting the very latest research, this book provides a critical review of the ways in which resilience of social-ecological systems, and the ecosystem services they provide, can be enhanced. With contributions from leaders in the field, the chapters are structured around seven key principles for building resilience: maintain diversity and redundancy; manage connectivity; manage slow variables and feedbacks; foster complex adaptive systems thinking; encourage learning; broaden participation; and promote polycentric governance. The authors assess the evidence in support of these principles, discussing their practical application and outlining further research needs. Intended for researchers, practitioners and graduate students, this is an ideal resource for anyone working in resilience science and for those in t

This book discusses the active and passive radar cross section (RCS) estimation and techniques to examine the low observable aerospace platforms. It begins with the fundamentals of RCS, followed by the dielectric, magnetic and metamaterials parameters of the constituent materials and then explains various methods and the emerging trends followed in this area of study. The RCS estimation of phased array including the mutual coupling effect is also presented in detail in the book. The active RCS reduction is carefully touched upon through the performance of phased arrays, sidelobe cancellers and mitigation of multipath effect. Providing information on various adaptive algorithms like least mean square (LMS), recursive least square (RLS) and weighted least square algorithms, the authors also mention the recent developments in the area of embedded antennas, conformal load bearing antenna, metamaterials and frequency selective surface (FSS) based RCS reduction.

Intellectual styles are individuals' preferred ways of using the abilities that they possess. The extent to which one can change his or her intellectual style is a question of interest to both researchers and the general public. This book presents the first comprehensive and systematic review of existing research on the malleability of intellectual styles. By critically analyzing research findings derived from both cross-sectional and longitudinal investigations performed over the past seven decades, Li-fang Zhang demonstrates that intellectual styles can be modified through both socialization and purposeful training. Professor Zhang elucidates the heuristic value of these findings for the development of adaptive intellectual styles in both academic and non-academic settings. She proposes further avenues of research that might advance scholarly understanding of the nature of and the potential for modifying intellectual styles.

The evolution of high-crowned teeth, hypsodonty, is a defining characteristic of many terrestrial herbivores. To date, the most prominent focus in the study of the teeth of grazing herbivores has been co-evolution with grasses and grasslands. This book develops the idea further and looks at the myriad ways that soil can enter the diet. Madden then expands this analysis to examine the earth surface processes that mobilize sediment in the environment. The text delivers a global perspective on tooth wear and soil erosion, with examples from the islands of New Zealand to the South American Andes, highlighting how similar geological processes worldwide result in convergent evolution. The final chapter includes a review of elodonty in the fossil record and its environmental consequences. Offering new insights into geomorphology and adaptive and evolutionary morphology, this text will be of value to any researcher interested in the evolution of tooth size and shape.

Fatigue can have a major impact on an individual's performance and well-being, yet is poorly understood, even within the scientific community. There is no developed theory of its origins or functions, and different types of fatigue (mental, physical, sleepiness) are routinely confused. The widespread interpretation of fatigue as a negative consequence of work may be true only for externally imposed goals; meaningful or self-initiated work is rarely tiring and often invigorating. In the first book dedicated to the systematic treatment of fatigue for over sixty years, Robert Hockey examines its many aspects - social history, neuroscience, energetics, exercise physiology, sleep and clinical implications - and develops a new motivational control theory, in which fatigue is treated as an emotion having a fundamental adaptive role in the management of goals. He then uses this new perspective to explore the role of fatigue in relation to individual motivation, working life and well-being.

本書基於CAS(Complex Adaptive System)理論視角，把企業組織能力系統視為複雜適應系統，對動態複雜環境中基於組織流程的企業組織能力系統的演化機制進行理論探索。在到昆明雲內動力股份有限公司、雲南銅業集團、雲天化集團、沈機集團昆明機床股份有限公司、昆明船舶設備集團、昆明貴研鉑業股份有限公司、昆明貴金屬研究所、雲南中煙工業有限責任公司煙草科學研究院、紅雲紅河集團以及紅塔集團進行深入

The control of individual quantum systems promises a new technology for the 21st century - quantum technology. This book is the first comprehensive treatment of modern quantum measurement and measurement-based quantum control, which are vital elements for realizing quantum technology. Readers are introduced to key experiments and technologies through dozens of recent experiments in cavity QED, quantum optics, mesoscopic electronics, and trapped particles several of which are analysed in detail. Nearly 300 exercises help build understanding, and prepare readers for research in these exciting areas. This important book will interest graduate students and researchers in quantum information, quantum metrology, quantum control and related fields. Novel topics covered include adaptive measurement; realistic detector models; mesoscopic current detection; Markovian, state-based and optimal feedback; and applications to quantum information processing.

Human memory, like other biological systems, has been subject to natural selection over the course of evolution. However, cognitive systems do not fossilize, which means that current researchers must

This volume presents eighteen case studies of natural disasters from Australia, Europe, North America and developing countries. By comparing the impacts, it seeks to identify what moves people to adapt, which adaptive activities succeed and which fail, and the underlying reasons, and the factors that determine when adaptation is required and when simply bearing the impact may be the more appropriate response. Much has been written about the theory of adaptation and high-level, especially international, policy responses to climate change. This book aims to inform actual adaptation practice - what works, what does not, and why. It explores some of the lessons we can learn from past disasters and the adaptation that takes place after the event in preparation for the next. This volume will be especially useful for researchers and decision makers in policy and government concerned with climate change adaptation, emergency management, disaster risk reduction, environmental policy and plannin

Intellectual styles are individuals' preferred ways of using the abilities that they possess. The extent to which one can change his or her intellectual style is a question of interest to both researchers and the general public. This book presents the first comprehensive and systematic review of existing research on the malleability of intellectual styles. By critically analyzing research findings derived from both cross-sectional and longitudinal investigations performed over the past seven decades, Li-fang Zhang demonstrates that intellectual styles can be modified through both socialization and purposeful training. Professor Zhang elucidates the heuristic value of these findings for the development of adaptive intellectual styles in both academic and non-academic settings. She proposes further avenues of research that might advance scholarly understanding of the nature of and the potential for modifying intellectual styles.

Climate change, population growth and the increasing demand for water are all capable of leading to disputes over transboundary water systems. Dealing with these challenges will require the enhancing of adaptive capacity, the improving of the quality of water-resources management and a reduction in the risk of conflict between riparian states. Such changes can only be brought about through significant international cooperation. Christina Leb's analysis of the duty to cooperate and the related rights and obligations highlights the interlinkages between this duty and the principles of equitable and reasonable utilisation and the prevention of transboundary harm. In doing so, she considers the law applicable to both international watercourses and transboundary aquifers, and explores the complementarities and interaction between the rules of international water law and the related obligations of climate change and human rights law.

This volume brings together a distinguished group of scholars working to address the puzzling durability of communist autocracies in Eastern Europe and Asia, which are the longest-lasting type of non-democratic regime to emerge after World War I. The volume conceptualizes the communist universe as consisting of the ten regimes in Eastern Europe and Mongolia that eventually collapsed in 1989–91, and the five regimes that survived the fall of the Berlin Wall: China, Vietnam, Laos, North Korea and Cuba. The essays offer a theoretical argument that emphasizes the importance of institutional adaptations as a foundation of communist resilience. In particular, the contributors focus on four adaptations: of the economy, of ideology, of the mechanisms for inclusion of potential rivals, and of the institutions of vertical and horizontal accountability. The volume argues that when regimes are no longer able to implement adaptive change, contingent leadership choices and contagion dynamics make co

This volume brings together a distinguished group of scholars working to address the puzzling durability of communist autocracies in Eastern Europe and Asia, which are the longest-lasting type of non-democratic regime to emerge after World War I. The volume conceptualizes the communist universe as consisting of the ten regimes in Eastern Europe and Mongolia that eventually collapsed in 1989–91, and the five regimes that survived the fall of the Berlin Wall: China, Vietnam, Laos, North Korea and Cuba. The essays offer a theoretical argument that emphasizes the importance of institutional adaptations as a foundation of communist resilience. In particular, the contributors focus on four adaptations: of the economy, of ideology, of the mechanisms for inclusion of potential rivals, and of the institutions of vertical and horizontal accountability. The volume argues that when regimes are no longer able to implement adaptive change, contingent leadership choices and contagion dynamics make co

This comprehensive Encyclopedia covers the full history of astronomy from its ancient origins in Africa, South America, the Middle East and China to the latest developments in astrophysics and space-based research. The initial articles, which are largely organised chronologically, are followed by numerous thematic historical articles on the constituents of the Solar System, types of stars, stellar evolution, active galaxies, cosmology and much more. These are followed by articles on tools and techniques, from the history of spectroscopy to adaptive optics. The last part of the Encyclopedia is devoted to the history of ground- and space-based telescopes and observatories, covering the full spectral range from gamma-rays through the optical waveband to radio waves. Informative and accessibly written, each article is followed by an extensive bibliography to facilitate further research, whilst consistent coverage from ancient times to the present makes this an ideal resource for scholars,

Genomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable basis for identifying which patients are most likely to benefit from each treatment. It is oriented to both clinical investigators and statisticians. For clinical investigators, it includes background information on clinical trial design and statistical analysis. For statisticians and others who want to go deeper, it covers state-of-the-art adaptive designs and the development and validation of probabilistic classifiers. The author describes the development and validation of prognostic and predictive biomarkers and their integration into clinical trials that establish their clinical utility for informing treatment decisions for future patients.

Genomics is majorly impacting therapeutics development in medicine. This book contains up-to-date information on the use of genomics in the design and analysis of therapeutic clinical trials with a focus on novel approaches that provide a reliable basis for identifying which patients are most likely to benefit from each treatment. It is oriented to both clinical investigators and statisticians. For clinical investigators, it includes background information on clinical trial design and statistical analysis. For statisticians and others who want to go deeper, it covers state-of-the-art adaptive designs and the development and validation of probabilistic classifiers. The author describes the development and validation of prognostic and predictive biomarkers and their integration into clinical trials that establish their clinical utility for informing treatment decisions for future patients.