Methods

While there is a wide selection of 'by experts, for experts’ books in statistics and molecular biology, there is a distinct need for a book that presents the basic principles of proper statistical ana

Early detection of cancer at the cellular level, even before anatomic anomalies are visible, is critical to more efficacious and cost effective diagnosis and therapeutic advances. In Cancer Nanotechno

Due to their rare combination of high chemical stability, exceptional optical and electrical properties, high surface-to-volume ratio, and high aspect ratio, carbon nanotubes (CNTs) have made an enorm

Recent critical advances in the field of immunotoxicology have led to incredible contributions to basic science, including crucial improvements in human risk assessment. In Immunotoxicity Testing: Met

This volume discusses the latest developments in clinical proteomics and describes in detail the algorithms used in publicly available software tools. It should be considered as a proteomics-bioinfor

For researchers, students, and scientists, Marco (Universidad Nacional de Cordoba, Argentina) assembles 11 chapters on the different aspects of metagenomics and its potential applications. Scientists

It is difficult to identify a defining moment that turned the tide toward less-polluting energy sources, but most people today have a fresh outlook on the environment and realize the importance of co

Due to their importance to cell biology, DNA topology-altering enzymes, collectively DNA topoisomerases and gyrases, have been studied thoroughly from a biochemical perspective, yet the expansion of

As two of the leading causes of death worldwide, heart disease and stroke represent a clear target for genomic research aimed at deciphering the genes and cellular pathways that underlie cardiovascul

MicroRNAs constitute a particularly important class of small RNAs given their abundance, broad phylogenetic conservation and strong regulatory effects, with plant miRNAs uniquely divulging their ancie

A Focused, State-of-the-Art Overview of This Evolving FieldPresents Various Techniques for GlycoinformaticsThe development and use of informatics tools and databases for glycobiology and glycomics res

In academic human rights research, especially legal human rights research, little attention tends to be devoted to questions of methodology. One reason for this may be that human rights scholars often

In recent years, our ability to understand and manipulate epidermal cells has increased tremendously, opening significant new possibilities in both basic science research and in regenerative medicine,

Use chemometric techniques to develop optimum separation conditions for capillary electrophoreses For all its advantages, capillary electrophoresis (CE) also carries significant disadvantages for the

This book interlaces financial concepts and instruments, such as arbitrage opportunities, admissible strategies, contingent claims, option pricing, default risk, ruin, with Brownian motion, diffusion

The Indian Statistical Institute (ISI), established in 1931, held a workshop and conference in December 2006, celebrating 75 years and also honoring Professor S.N. Roy, an eminent statistician. Presen

Since the publication of the first edition, the number of unique heritable mtDNA mutations recognized as being associated with bioenergetic dysfunction, cell death and disease has grown. Likewise, ou

Thanks to high-speed computers and advanced algorithms, the important field of modelling multiphase flows is an area of rapid growth. This one-stop account – now in paperback, with corrections from the first printing – is the ideal way to get to grips with this topic, which has significant applications in industry and nature. Each chapter is written by an acknowledged expert and includes extensive references to current research. All of the chapters are essentially independent and so the book can be used for a range of advanced courses and the self-study of specific topics. No other book covers so many topics related to multiphase flow, and it will therefore be warmly welcomed by researchers and graduate students of the subject across engineering, physics, and applied mathematics.

The unique chromosome dynamics of meiosis have fascinated scientists for well over a century, but in recent years there has been a proliferation of new data concerning the pairing, recombination, and

The last ten years have witnessed a monumental increase in our understanding of plant hormones. A decade ago, scientists were forced to rely on vague ideas about hormone action; today, these have bee

Scan statistics is currently one of the most active and important areas of research in applied probability and statistics, having applications to a wide variety of fields: archaeology, astronomy, bio

Despite its remote and seemingly rigorous environment, the Antarctic is the world's most important habitat for seals, currently supporting more seals than all other parts of the world combined. As various national Antarctic programmes were established to study these animals, the need to standardize techniques became apparent. This book, arising from work by the Scientific Committee on Antarctic Research (Group of Specialists on Seals), gives a detailed account of well-tried and, where possible, agreed methodologies, techniques, procedures and rationale for the collection and initial analysis of data on the biology and population ecology of Antarctic seals. This volume will not only help facilitate comparisons between different regions of Antarctica, but will also provide a guide for those studying seals in other parts of the world and those carrying out research on other large mammal species.

Seven Common Questions that Define Organizational TransformationsWhy does an organization need to transform?What is a transformation?What challenges does a transformation create?How can you respond to

The type of control system used for electrical machines depends on the use (nature of the load, operating states, etc.) to which the machine will be put. The precise type of use determines the control

Plant genomics is a growing and constantly evolving field of study, one which has gained much ground in past years through the development of advanced research and data management tools. In Plant Gen

Environmental epidemiology is the study of the environmental causes of disease in populations and how these risks vary in relation to intensity and duration of exposure and other factors like genetic

Environmental epidemiology is the study of the environmental causes of disease in populations and how these risks vary in relation to intensity and duration of exposure and other factors like genetic

As increasing global population and continuing economic development ensure the need for further production and cultivation of maize, the necessity of the application of transgenic technology to this

Protein phosphorylation controls many basic cellular processes, such as cell growth, differentiation, migration, metabolism, and cell death, and its study can provide key insights into the signal tra

Until now, novices had to painstakingly dig through the literature to discover how to use Monte Carlo techniques for solving electromagnetic problems. Written by one of the foremost researchers in the

With revenues from the top five therapeutic antibodies accounting for a majority of the recent pharmaceutical sales, the research and development in the field has exploded over the past several years

First published in 1987, this book describes tissue (cell and organ) culture techniques which could be used at a critical predevelopment stage to screen for drug-inducing toxicity or to analyse the molecular mechanisms of toxicity at a later stage in parallel with investigative studies. This type of research has important ethical, financial and scientific implications. In particular, less animals and compound are required in in vitro research and more detailed information at the cellular and subcellular levels can be obtained. The volume brings together the once disparate knowledge of cultural techniques and thus provides an important reference work for industrial and academic toxicologists. It could also form a framework for discussion of potential improvements and modification of toxicity testing.

Environmental impact assessment (EIA) is now firmly established as an important and often obligatory part of proposing or launching any development project. Delivering a successful EIA needs not only

Due to its efficacy in animal models, cellular therapy using human hepatocytes is being evaluated worldwide as an alternative to organ transplantation in patients with liver-based metabolic disease a

Since the 1971 White House Conference on Aging in the United States, the need to move from religiosity into new areas such as Spiritual Assessment and Spirituality has emerged. This movement has picke

This is an account of the theory of certain types of compact transformation groups, namely those that are susceptible to study using ordinary cohomology theory and rational homotopy theory, which in practice means the torus groups and elementary abelian p-groups. The efforts of many mathematicians have combined to bring a depth of understanding to this area. However to make it reasonably accessible to a wide audience, the authors have streamlined the presentation, referring the reader to the literature for purely technical results and working in a simplified setting where possible. In this way the reader with a relatively modest background in algebraic topology and homology theory can penetrate rather deeply into the subject, whilst the book at the same time makes a useful reference for the more specialised reader.

Over the course of the past decade, there have been remarkable advances in the study of human pathogenic fungi. These developments have taken place throughout a wide range of disciplines, and have co

With the development of robust cell-culturing systems capable of Hepatitis C Virus replication and infection, the past decade has witnessed an explosion of innovative research directed at understandi

Clinical epidemiology provides the scientific basis for the practice of medicine due to its focus on the diagnosis, prognosis and management of human disease using appropriate research design, measur