Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

～創造力爆棚的造型VISUAL BOOK第二彈～原型師的腦袋裡都在想什麼？什麼樣的WORLDVIEW、人物設定才能創造出獨特作品？27位頂尖藝術家的靈感發想初公開！【達人推薦】◎「窺見職業原型師的製作思路與方法，每期的分享都大有斬獲！」──R-one studio◎「與其說是造型，不如說是魔法──用電腦、黏土、顏料為媒介施放的魔法（有點超展開的），收錄豐富作品、詳細介紹製作技法，讓人體驗從無到有創

從基本概念到重要的演算法，再到處理平臺和實際案例，作者為美妙圖形世界編寫了一本兼具指導性與說明性的參考指南。"—Kirk Borne, PhDPrincipal Data Scientist and ExecutiveAdvisor, Booz Allen Hamilton"一本實用且資訊豐富的指南，幫助你藉由使用圖形演算法檢測模式和結果，來獲取更多洞察力，圖形資料庫開發人員的必讀書籍。"—Lua

Filled with exciting, strange, funny, and sometimes frightening tales, Boy is the enthralling story of Roald Dahl's childhood and early life.Penguin Readers is a series of the best new fiction, essent

◆人人都有的EXCEL＋超詳細步驟教學＝高CP值學會統計分析。◆專業理論深入淺出，搭配實例整合說明，從報表製作到讀懂，一次到位。◆完整的步驟操作圖，解析報表眉角，讓你盯著螢幕不再霧煞煞。◆本書專攻基礎統計技巧，讓你掌握資料分析力，在大數據時代脫穎而出。◎大學教授傾囊相授統計分析手法，帶領你掌握資料分析能力，前進大數據時代。大數據(Big data)時代下，統計學愈來愈夯，資料分析全方位應用在各種工

本書內容共分為八大單元，依序為基本概論、Digital Logic數位邏輯、Operation System作業系統、System Program系統程式、Programming Language程式語言、Data Structure資料結構、網路、Datebase資料庫等重點觀念。 本書除了重點整理計算機概論的相關理論之外，更蒐集歷年高普特考試題，強化基本觀念，讓考生在短時間內以最

行銷企劃、市場分析、統計預測、財務金融、風險管理...都該學！養成大數據分析力的第一本書！資料分析、資料科學都是近來非常夯的關鍵字，與其相關的工作職務紛紛冒出，形成一股勢不可擋的大數據分析學習熱潮。只是聽說學資料分析都得具備一定的技術能力 (例如要會撰寫 Python、R...程式)，往往讓底子不夠、或非資訊背景的人止步...沒關係！不管您身處什麼領域、技術背景如何，本書就是為了想搭上這波學習熱潮

現代企業生存在劇變的大時代中，尤其2015年相繼發布《巴黎協議》和「聯合國永續發展目標（Sustainable Development Goals, SDGs）」，全面牽動各國政府的政策、市場規範，新的企業營運風險和機會，深深影響企業的商業活動。 隨著國際、國家層級的永續發展規約日益明確，日趨嚴苛，越來越多企業將CSR從被動回應轉換為內部常態化的管理議題，並且從過往以CSR資訊揭露為主，提升至主動

BabyLit® Storybooks give classics new life for the next generation of early readers.In Anne of Green Gables, preschoolers get to know the beloved redheaded orphan Anne Shirley, who is sent to live wit

By award-winning Waterstones Children's Laureate Joseph Coelho, the first book in the Luna Loves... series. Every week Luna looks forward to one special day: the day when she discovers magic among the library shelves, the day she gets to spend with her dad. Exploring the books, Luna and her dad find magic, mystery and even start to mend their own history. An inspiring story that celebrates alternative families and the magic of books from one of the UK's greatest award-winning poets for children, and Children's Laureate, Joseph Coelho. Endorsed by Amnesty International: "This is a touching reflection on the power of reading to bring families together; Fiona Lumbers’ illustrations convey Luna’s vivid inner life, while Coelho’s lyrical style celebrates the joyful curiosity of early childhood." Amnesty International "An ode to love and different kinds of families, with lyrical text and richly coloured, warm illustrations." Irish Independent, Best Books of 2017 Other books in the Luna Loves

本書改版時收錄DSM-5○Ｒ自閉症類群障礙症及注意力缺失／過動症（ADHD）的新診斷資料，以及最新的治療研究，當中包括：❖新增文獻說明遊戲治療是兒童職能治療中，具影響力及療效的方式。❖各國自閉症類群障礙症盛行率研究。❖各國自閉症類群障礙症兒童的感覺處理障礙發生率。❖引入新的感覺統合治療對自閉症類群障礙症的療效。❖更新注意力缺失／過動症（ADHD）的診斷標準。❖新增Reynold 教授針對ADHD的

原來我們所認為的「健康飲食」、「蔬果飲食」，正是讓人類生病的源頭！過敏、疲勞、關節炎、腸躁症、腎臟病……可能都是來自於你的飲食！美國權威營養學醫師──史提芬‧岡德里（Dr. Steven R Gundry M.D.），帶來全新徹底顛覆飲食思維的科普知識！★美國Amazon網站書籍總榜TOP 2！★《紐約時報》非文學類書籍榜第2名！★Amazon網站健康類>疾病與身體疾病>免疫系統、瘦身

BabyLit® Storybooks give classics new life for the next generation of early readers.In The Jungle Book, preschoolers can tag along on Mowgli’s thrilling adventure, meeting wolves, elephants, and even

＊華文世界最知名最專業「啟彬與凱雅的爵士棧」廣受好評之教學文章集結出版。 ＊從Groove的根源開始探索追尋，一路從非洲到南北美洲，了解形成Blues、Ragtime、New Orleans Jazz、Swing、Bebop、Funk、Afro-Cuban (Salsa)、Calypso、Reggae、Samba、Bossa Nova、R&B、Gospel、Motown、Soul、Rock

Bruce Attleton dazzled London's literary scene with his first two novels but his early promise did not bear fruit. His wife Sybilla is a glittering actress, unforgiving of Bruce's failure, and the cou

A new novelty board book series aimed at children from birth, the series uses moving tabs or flpas on all 5 spreads as well as the cover to introduce children to early learning concepts (sea

This fun box set is filled with nine sturdy, fun, educational board books that support children's early learning. Topics include Animals, Letters and Counting, Things that Go, Colors and Shapes, and m

BabyLit® Storybooks give classics new life for the next generation of early readers. Ahoy! Come sail the ocean blue with Captain Ahab, Ishmael, Queequeg, and the rest of the crew! The search is on for

★ 全球「長壽藍區」實證揭密：活到100歲的生活方式★ 不靠極端節食，用日常習慣打造健康與長壽★ 50種長壽超級食物＋實用食譜，一次掌握本書透過對全球「藍區」長壽人群的研究，揭示健康與長壽的關鍵在於日常生活習慣，而非極端手段。從飲食、社群到人生目標，作者提出一套可實踐的行動方案，並提供長壽食材與食譜，幫助讀者打造更健康的生活模式。內容結合科學研究與真實案例，是追求身心平衡與長壽人生的重要指南。Bestselling author Dan Buettner reveals how to transform your health using smart nutrition, lifestyle, and fitness habits gleaned from longevity research on the diets, eating habits, and lifestyle practices of the communities he's identified as "Blue Zones"—those places with the world's longest-lived, and thus healthiest, people, including locations such as Okinawa, Japan; Sardinia, Italy; Costa Rica's Nicoya Peninsula; Ikaria, Greece; and Loma Linda, California.With the audacious belief that the lifestyles of the world's Blue Zones could be adapted and replicated in towns across North America, Buettner launched the largest preventive health care project in the United States, The Blue Zones City Makeovers, which has impacted the health of millions of Americans since 2009. In The Blue Zones S

潛入深海世界，用一張張貼紙畫出繽紛海洋！本書是專為孩子設計的創作活動書，不用顏料、不會弄髒，只要按照編號貼上對應貼紙，就能完成十幅低多邊形風格的海洋畫作，包括海豚、章魚、鯊魚等熟悉海洋生物。每頁厚紙材質可撕下收藏，也適合展示與送禮。從撕貼動作到色彩變化，過程令人專注又充滿成就感，既是手作遊戲，也是美感與專注力的練習工具！Paint by Sticker is the most exciting new idea in activity books, both for grown-ups and kids. A compelling activity for crafters and artists, doodlers and colorers of all ages, each Paint by Sticker Kids book includes everything you need to create ten vibrant, full-color “paintings.” The original images are rendered in low-poly, a computer graphics style using geometric polygon shapes to create a 3D effect. As in paint-by-number, each template is divided into spaces, each with a number that corresponds to a particular sticker. Find the sticker, peel it, and place it in the right space. Add the next, and the next, and the next—it’s an activity that’s utterly absorbing, both in the pleasure of peeling and sticking and the growing satisfaction of watching a “painting” come to life, emerging from a flat black-and-white illustratio

Help your child learn to identify colors with this engaging early-learning play set. Little ones will enjoy matching the puzzle pieces with the colors on the pages, while also learning core vocabulary

Early this century Enrico, a young intellectual, leaves the abundantly diverse Austro-Hungarian city of Gorizia with its mixed population and culture, to spend several years living on the Patagonian p

愛比賽的兔子遇上剛醒來想堆雪人的熊，兩人為了誰的雪人最棒鬧出不少笑話，還引來一場雪崩和一隻餓狼！從「便便」到友情，笑點不斷的圖文小說，適合喜歡《Oi Frog!》系列的小讀者。Hilarious, gorgeously illustrated and with a classic feel, this is the next step up for readers of Kes Gray and Jim Field's bestselling OI FROG!'Rabbit's Bad Habits is a breath of fresh air in children's fiction, a laugh-out-loud story of rabbit and wolf and bear, of avalanches and snowmen. The sort of story that makes you want to send your children to bed early, so you can read it to them.' Neil GaimanFrom novelist and playwright Julian Gough, and the winner of the Roald Dahl Funny Prize, Jim Field, comes a laugh-out-loud funny story of a rabbit and bear who discover that things are always better when they're shared with a friend ...Bear wakes up early from hibernation. If she can't sleep, then at least she can make a snowman. Rabbit has never made a snowman, but he definitely wants to make one that's better than Bear's. But with an avalanche and a hungry wolf heading his way, Rabbit soon realises

The funny and fabulous rhyming picture book from the number one bestselling author and illustrator of The Gruffalo, Stick Man and Zog. The smallest fish can tell the tallest tales ... ‘"Sorry I'm late, Miss.I set off really early But on the way to school I was captured by a squid. I wriggled and I struggled till a turtle came and rescued me." “Oh, no, he didn't.” “OH, YES, HE DID.”’ Tiddler is a little fish with a BIG imagination! Every day he tells a tall tale. But did he really ride a seahorse? Did he really meet a mermaid? And who will believe him when he really does get captured in a net? Shiny foil highlights on the cover makes this a special gift for toddlers The fabulously funny bestseller from the UK’s number one picture book author and illustrator Perfect read-aloud rhyming text and stunning pictures on every page with lots of details to spot The ideal gift for children starting school Shiny foil highlights on the cover makes this a special gift for toddlers From the creators

本書是美國紐約大學戲劇治療課程創辦人，也曾任該所所長暨國際期刊《心理治療藝術》（The Arts in Psychotherapy）的榮譽退休主編：藍迪（R. Landy）教授，運用其最擅長的角色理論所建構的角色系統之「角色方法」來撰寫戲劇治療的過程與案例。 作者以其社會學、人類學、文化研究及心理學等不同學門之研究與實務之專業素養，深入淺出且生動地描繪與解釋戲劇治療的角色方法，同時運用「角色」

**NOW THE WINNER OF THE 2022 BEST DIRECTOR OSCAR AND TWO 2022 BAFTA AWARDS**Discover Thomas Savage's dark poetic tale of a small town in early 20th century America. Phil and George are brothers, more than partners, joint owners of the biggest ranch in their Montana valley. Phil is the bright one, George the plodder. Phil is tall and angular; George is stocky and silent.Phil is a brilliant chess player, a voracious reader, an eloquent storyteller; George learns slowly, and devotes himself to the business. Phil is a vicious sadist, with a seething contempt for weakness to match his thirst for dominance; George has a gentle, loving soul. They sleep in the room they shared as boys, and so it has been for forty years.When George unexpectedly marries a young widow and brings her to live at the ranch, Phil begins an relentless campaign to destroy his brother's new wife. But he reckons without an unlikely protector. From its visceral first paragraph to its devastating twist of an ending, The P

台灣第一本透過大數據系統(Big-Data-System)回測技術指標在台指選表現的書籍，並打造「進化版選擇權策略指標」以協助投資人找尋最佳的交易聖杯。本書出版的目的，乃希望透過選擇權策略的回測結果，引導投資人進入選擇權策略交易的領域。內容除了著重在簡易上手的技術指標應用外，於選擇權策略的改良上，作者更特地保留原先指標的運算思維，僅加入有限的參數，方便讀者在策略運行上能有所遵循，此外更達到優化績效

本書以鄂圖曼帝國裝飾藝術為靈感，融合摩爾、波斯與拜占庭風格，呈現華麗而富層次的十字繡設計。書中收錄多款重複圖樣與邊框，運用寶石色調，適合應用於抱枕、毯子與桌巾。搭配清楚易懂的圖表，讓讀者在創作中感受跨文化工藝之美，是兼具實用與美感的刺繡靈感書。Inspirational cross-stitch designs with Moorish, Persian, and Byzantine flairOttoman Empire once stretched from the Persian Gulf to the Adriatic Sea, covering much of Southeast Europe, Western Asia, and North Africa, and it is the inclusion of so many cultures that gives its decorative art such ornamentation. With Moorish, Persian, and Byzantine influences mixed with European folk art there is a wealth of design to choose from. This book offers beautiful repeat patterns and borders using rich jewel colors as well as styles evident in Ottoman ornamental art. The motifs work beautifully on cushions, blankets, and table linens. With easy-to-follow charts and many options of Ottoman-inspired traditional designs, this is an inspirational project book.

AngularJS Web Application Development Cookbook AngularJS 是當今 Web 開發領域中最受歡迎的框架之一。其設計崇尚簡潔風格，能夠為許多複雜的網頁開發工作提供優雅的解決方案。本書能夠使你深入瞭解這款強大且高價值的工具，提供超過90項方法及秘訣，藉此解決各式各樣的問題。無論你使用 AngularJS 的目的為何，本書都是你所不可或缺的重要資源。

Support students' phonetic development as they practice key first grade phonics skills. Focus on phonics with fun and engaging activity pages that are research based and support current standards. Thi

Support students' phonetic development as they practice key second grade phonics skills. Focus on phonics with fun and engaging activity pages that are research based and support current standards. Th

An entertaining diary format based on this much-loved fairy tale, told from the perspective of Cinderella herself. Pop-ups bring the book to life, perfect for engaging early readers. Multi-media illus

An entertaining diary format based on this much-loved fairy tale, told from the perspective of Jack himself. Pop-ups bring the book to life, perfect for engaging early readers. Multi-media illustratio

An early bestseller from the author of the fabulous Shopaholic series. Fleur is beautiful, unscrupulous, and has a large wardrobe of black designer suits. With the help of The Times announcements page

Reads R to L (Japanese Style), for T audiences. Mitsu has just started working as a window washer, a dangerous job that five years earlier led to the loss of his father. As Mitsu struggles with being the new guy—making mistakes, struggling to keep up, petty workplace resentments—he also discovers the simple pleasures of befriending his coworkers, enjoying time off and getting to know his absent father through the eyes of his colleagues.

An early bestseller from the fabulous author of the Shopaholic series. Chloe needs a holiday. She's sick of making wedding dresses and her partner Philip has trouble at work. Her wealthy friend Gerard

After bursting onto the fantasy scene with his acclaimed debut novel, Elantris, and following up with his blockbuster Mistborn trilogy, Brandon Sanderson proves again that he is today’s leading master of what Tolkien called “secondary creation,” the invention of whole worlds, complete with magics and myths all their own.Warbreaker is the story of two sisters, who happen to be princesses, the God King one of them has to marry, the lesser god who doesn’t like his job, and the immortal who’s still trying to undo the mistakes he made hundreds of years ago.Their world is one in which those who die in glory return as gods to live confined to a pantheon in Hallandren’s capital city and where a power known as BioChromatic magic is based on an essence known as breath that can only be collected one unit at a time from individual people.By using breath and drawing upon the color in everyday objects, all manner of miracles and mischief can be accomplished. It will take considerable quantities of e

以權威性的Deitel Live-Code以及管理程式碼的方式介紹Visual C++R .NET，本書附有數百個完整的程式，並以螢幕擷取畫面顯示實際的輸出結果。關於WindowsR、.NET以及網際網路與全球資訊網程式設計也有詳盡的介紹，小技巧的提示與建議性的習慣與警示使讀者不易犯錯。理論透徹，條理分明。

From patriotic songs that stir the soul to cowboy songs of early settlers, this is a terrific collection of songs about America. Children can learn as they hear “The Star Spangled Banner,” the names

本書以系統化方式介紹資料包絡分析法（Data Envelopment Analysis, DEA），強調理論與應用，適合對績效評估與管理有興趣的讀者閱讀。本書深入淺出介紹DEA基本理論與最新發展模式，並採個案方式，為讀者說明DEA在管理實務上之應用。本書共二篇，理論篇與應用篇

本報告簡單扼要介紹幾個主要國家3C整合科技產業的概況、發展重點、R&D經費、國家型計畫與市場產值，以瞭解各國之競爭力，進而對我國未來3C整合科技及產業發展作一前瞻性之規劃。