Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

在資訊爆炸、價值混亂的時代，多數人選擇隨波逐流，但真正改變人生的人，往往是敢於逆流而行的人。 《逆行者》是一部結合教練學、人生哲學與實務觀察的思維成長之書。作者透過近三十年的教學、企業培訓與人生觀察，提出一套影響人生結果的關鍵概念――「狀態學」。 書中指出：真正決定一個人成敗的，不只是能力或方法，而是你所處的「狀態」。當狀態正確，再普通的方法也能走出成果；當狀態錯誤，再好的策略也難以發揮。 本書從「認知」、「選擇」、「信念」、「責任」、「決策」等面向出發，帶領讀者重新審視自己的人生： 如何突破固定思維，建立成長型思維 為什麼「做一個有價值的人」比成功更重要 為何多數人困住自己，是因為認知與潛意識 如何從被動反應（React）轉為主動回應（Response） 如何做出真正改變人生的決策 《逆行者》不是一本勵志書，而是一面鏡子。 它幫助你看見真正的自己，理解人生的運作邏輯，並在洪流之中找到屬於自己的方向。 如果你不想只是隨波逐流，那麼這本書，將會是你逆流而上的起點。

Meet the busy London Guards in this bright, rhyming board book, with push, pull and slide pages to play along.Toddlers will love to join in with all the action, as they discover a day in the life of a London guard. Slide the tab to help him put his hat on, pull the page to bring the changing of the guard ceremony to life . . . and more!With colourful illustrations from Marion Billet, a fun rhyming text to share together, and lots of things to spot – from iconic busbies to cups of tea! – this sturdy board book is the perfect London present for little ones who like to play as they read.Discover more London fun withBusy London, Can You Find the King in London?andWhizzy Wheels: My First London Bus.

Winner, 2025 Best Baby Book Prize from the French Ministry of Culture From family trips to ocean dips, experience summer's everyday magic in this sturdy, neon pop-up book. With playful illustrations, engaging text, and pop-up surprises that toddlers (and parents) will love!Designed especially for little hands, this bright, bold pop-up book brims with the joy of summer in every turn of the page. Perfectly portable and shaped for toddlers' hands, this sturdy board book features six playful pop-up scenes that leap from the pages with high-contrast neon images - the yellow of sunshine and the pink of summer sunsets.Celebrate the magic of summertime, from a busy bee zipping between blossoms to a bumpy ride in the family van, from spreading sunscreen on our faces to enjoying bare feet on a beach, and from diving into sunset seas to counting the stars at night. This book brings all our most-loved summer moments to life in a way that's both familiar and fresh, clever and surprising. Every page

Step inside a medieval castle on the eve of a grand jousting tournament when the arrival of a mysterious knight sets tensions rising. In this story you'll discover how knights are trained, how they dress for battle, watch jousting and sample foods sold to excited crowds.- Told in lively comic book style- Perfect for school projects

The second title in a cosy crime puzzle series following the adventures of super-sleuth Ivy and her grandpa, Bearlock Holmes. When a dinosaur fossil disappears from Bearona's remote Jurassic Ridge, Ivy and Bearlock face their trickiest case yet. With 15 interactive puzzles woven through the story, readers can join the duo as they unravel a mystery inspired by real-world fossils, evolution and conservation.Featuring charming illustrations and a heartwarming cast, this series combines cosy mystery with STEM - perfect for curious young detectives. Also available: The Case of the Missing Flower (Ivy and Bearlock 1)"5+ readers with an interest in detective stories and nature will enjoy helping Ivy and her grandpa solve the case in this absorbing, beautifully designed puzzle book." - Guardian

★ 永遠十歲的女孩，迎來100歲生日！★ 帶著小狗與會說話的檸檬，展開奇幻旅程★ 爆笑又溫柔的童話冒險★ 一個關於「好人生」的大問題伊蒂絲有兩個神奇的禮物：能讓東西活過來的魔法，還有——永遠十歲。但一百年後，她開始覺得：一直當十歲，好像也沒那麼好。於是，她帶著聰明的小狗和一顆會說話的檸檬，踏上尋找仙子的旅程，希望解除魔法，開始真正的人生。A philosophical adventure story for early readers that playfully combines fairytale with absurd comedy to ask a big question about what makes a good life.As a newborn, Edith received two gifts: the ability to bring any object to life and eternal childhood. That's why today, 100 years later, Edith is celebrating her centenary as a ten-year-old. What will she wish for this time? Certainly a new life-being ten forever has its downside. On her birthday, Edith sets off to find the fairy who bewitched her and reverse the spell. She takes her only friends, a wise dog and a talking lemon. Fully illustrated in color, this one-of-a-kind chapter book bursts with good things: the dry witof a faithful dog, a fairytale adventure, camping, boating, friendship and danger, and a question that matters.

The brand new summer romance set in Dream Harbor from the #1 New York Times bestselling author of The Pumpkin Spice Café and The Strawberry Patch Pancake House! “Another gentle small-town romance with Hallmark movie vibes… Dream Harbor remains a cozy spot to linger” Publisher’s Weekly "A delightful escape filled with Gilmore’s signature whimsy and coziness” Hannah Bonam-Young, New York Times bestselling author *** The greatest love is the one you never expected to find Daisy is fed up with being unlucky in love. And since Mayor Kelly declared her beloved flower shop cursed in one of his infamous visions, business has been slow. Dream Harbor newcomer Elliot has been adjusting to small-town life following his own relationship turmoil.And until now he’s avoided the flower shop at all costs. If the mayor is correct, he doesn’t need any more bad luck in his life. When he finds himself walking through the door of the Daisy Chain Flower Shop, he doesn’t expect it to be a life-changing moment.

Parents should pass down stories, not spirits...Avery and Carlos Tam have built their lives on logic, not legends. Carlos, the host of a hit reality show that exposes paranormal hoaxes, has made a name disproving the supernatural.But when they travel to his ancestral home in the Philippines, darkness clings to every corner. The mirrors are shrouded. The housekeeper won't stay in the house alone. And no one will speak of the tragedies the family has seen.Then a brutal car crash leaves Carlos trapped in his own body--silent, helpless, and utterly vulnerable. As Avery tends to him, the house begins to stir. It watches. It listens. And it speaks--in a voice only Carlos can hear--offering a twisted kind of comfort.And as the lies buried by Carlos and his family begin to surface, Avery must confront the truth: if the past won't rest, their future may never begin.Some inherit memories. Others inherit monsters.

What if Meg had to become a Greek god? Now in a deluxe paperback edition featuring gorgeous sprayed edges! Become one with the gods in this tale based off of Disney's Hercules, from the New York Times bestselling series that reimagines beloved Disney classics in a creative way! After Hercules proves he's a true hero and regains his godship, all seems right in the world. That is, until Zeus tells Meg that she can't be with Hercules because she's, well, mortal. Luckily, Hera has a solution, offering Meg a chance to prove herself worthy of a spot on Mt. Olympus--as a god. All Meg has to do is complete a mysterious quest. The mission? Oh, just to rescue her ex's current wife from the Underworld. The ex-boyfriend she saved by selling her soul to Hades. The ex-boyfriend who immediately moved on to someone else while she was stuck in the Underworld. Can Meg put her past behind her and use her quick-wit to defeat monsters and gods alike, including the nefarious Hades? Will she finally figure o

It’s Swing Time! Join Ladybird as she tries out different kinds of swings to find her favourite in this playful picture book. Join Ladybird on a joyful journey through every kind of swing imaginable in this playful picture book, brought to life with a unique, interactive reading format! What kind of swing is it, Ladybird? Is it a friendship swing? A family swing? One that comes with a big hug or a sweet‑smelling flower? Follow Ladybird as she tries out all sorts of swings and meets lots of friends along the way. There’s a friendship swing, a rainbow swing, a swing that dips deep underwater and another that soars high into the sky. There’s even a sleepy swing that invites dreamy yawns . . . and one that proves to be just a little bit risky. Designed in a dynamic vertical format that mirrors the motion of swinging, this book encourages young readers to turn, tilt and explore the page in surprising ways. And at the end, a special gatefold swings open to reveal the most exciting discovery

多益王牌名師關正生獨家「神速解題法」英文弱底也能突破600分！超人氣英語教學名師關正生，自2006年起至今每在多益測驗中必拿990滿分，在日本已出版超過130本英語學習書籍，總銷量超過300萬本！他倡導「理解」式學習，強調掌握語言的核心原理，而非死記硬背。如果你是第一次應考的考生、不知道從哪開始準備、自認英文基礎薄弱、想掌握高分考點，卻不擅長常見的考試技巧，那麼這本專為只想用「一本攻略書」的考生所設計的全方位多益指南，就是為你所設計的學習方式。市面上的多益書籍過分強調考試技巧，但對英語弱底的考生來說，往往程度無法應對，反而適得其反，更花時間。作者在掌握最新出題趨勢的基礎上，深入分析多益的經典題型，並且搭配清楚易懂的解析，考生一看就懂。其獨家的「神速解題法」，強調釐清基礎觀念，穩扎穩打的學習，不過度依賴技巧，題目自然看得懂、聽得懂。本書依照「由廣到精」的學習邏輯設計，從大範圍建立基礎，逐步聚焦，最終以完整模擬測驗驗收實力。內容涵蓋 Part 1～7，分為「題型攻略 → 攻略特訓 → 實戰演練 → 完整模擬測驗」四大階段：先透過題型攻略掌握各題型重點，再以攻略特訓強化解題技巧，進一步透過實戰演練累積應試能力，最後以一回完整模擬測驗檢視學習成果。搭配詳盡解析，幫助考生清楚掌握優勢與弱點，建立穩定的作答節奏。獨家附贈「考前衝刺別冊」！收錄備考 TIPS、各大題重點整理與完整模擬測驗，考前快速翻閱，一次掌握關鍵重點，穩定心態、精準上場，助你順利突破 600 分！日本Amazon讀者超高好評！跟其他攻略書相比，這本的解說方式有其獨到之處，更能幫助讀者理解多益測驗的精髓。——D考生第一次考多益的人一定要讀這本書！只要熟讀書裡的攻略，正式測驗真的能考取高分！——H考生除了攻略、練習題之外，本書額外收錄的別冊還提供了考試當天的熱身技巧，以及考前複習重點整理，幫助我在考試當天保持冷靜！——T考生本書特色四大應考步驟，讓你從新手變高手！Step 1 題型攻略・快速掌握出題重點全面盤點常考題型、高頻用字到答題關鍵，迅速了解出題邏輯及答題對策，考生一看就懂！Step 2攻略特訓・把觀念轉化為實力把在題型攻略所學到的解題技巧，應用在特訓練習中。再從解析裡加強基礎觀念、避開常見陷阱，鍛鍊出秒解的硬實力！Step 3實戰演練・反覆訓練熟悉節奏依真實考試難易度設計題目，在反覆練習中掌握作答節奏並熟悉

Learn how mammals survived the test of time in this volume of Science Comics, the smash-hit STEM graphic novel series that has sold over a million copies!Mammals are survivors--when dinosaurs went extinct, they survived. From lush jungles to deep oceans to sweltering deserts, mammals now dominate nearly every environment on Earth. But how did they do it? Take a trip back in time and discover how extreme changes in climate have pushed mammals to evolve new traits, including hooves, claws, tusks, big brains, and even blow holes. Join us as we explore our mammalian history, and maybe the past will hold the key to surviving in the future.

★ 如果愛麗絲「太晚回到仙境」，世界會崩壞嗎？★ 《Twisted Tales》系列再出擊，顛覆《愛麗絲夢遊仙境》經典結局★ 豪華刷邊版收藏登場，黑暗童話迷必收！本書以「愛麗絲太晚回到仙境」為核心設定，描繪她在現實與幻想交錯中，重新踏入危機四伏的仙境，對抗紅心皇后的統治。結合奇幻冒險與自我成長，情節緊湊、氛圍黑暗，是經典童話的全新詮釋。What if Wonderland was in peril and Alice was very, very late?Now in a deluxe paperback edition featuring gorgeous sprayed edges! Climb down the rabbit hole in this tale based off Disney's Alice In Wonderland, from the New York Times bestselling series that reimagines beloved Disney classics in a creative way. Alice is different than other eighteen-year-old ladies in Kexford, which is perfectly fine with her. She'd rather spend golden afternoons with her trusty camera or in her aunt Vivian's lively salon, ignoring her sister's wishes that she stop all that "nonsense" and become a "respectable" member of society. Alice is happy to meander to Miss. Yao's teashop or to visit the children playing in the Square. She's also interested in learning more about the young lawyer she met there, but just because she's curious, of co

Have you ever wondered what stars are made of, or how they blaze into life? What about how a black hole works, or whether there's alien life somewhere in the universe?These are the kinds of incredible questions that astronomers spend their days trying to answer. This book won't only give you basic answers, it really digs in to explain some seriously cool and mysterious ideas, from gravity to the origin of the universe to the problem of warping through spacetime.Find out what Astronomers and Cosmologists have discovered so far, how on Earth they figured it all out, and the head-scratching problems they're still puzzling over in this thrilling introduction.Chapters in this book include:- Space rocks- How light works- Studying stars- Black holes- Gravity- Is anybody out there?Exploring complex ideas in easy-to-digest chunks, with expert input from astronomer Dr. Sheila Kanani MBE, Astronomy for Beginners is perfect for space-obsessed children aged 10 and above.Discover more from Usborne's

Discover the incredible story of Cristiano Ronaldo, an inspirational athlete, global megastar and one of the world’s greatest footballers. Born on the island of Madeira in Portugal, Cristiano grew up playing football from a very young age. With determination and self-belief, he pursued his dream of becoming a professional player, overcoming setbacks and challenges – including surgery for a heart condition called tachycardia – along the way. From his first matches in local clubs to international stardom, his journey shows the power of hard work, resilience and courage. This inspiring book introduces children to Ronaldo’s record-breaking career, including three consecutive Premier League titles with Manchester United, victories in the Champions League and Club World Cup, and his record transfer to Real Madrid in 2009. Ronaldo’s remarkable, record-breaking career is a story of hard work and determination, one that is sure to resonate with young sports fans, inspiring them to dream big and

From hilarious MEGA-BESTSELLING author Katie Kirby comes a brand-new story in the phenomenal LOTTIE BROOKS series!Pack your bags, and put on your helmets, for Lottie s latest hilarious diary! She s off on a ONCE IN A LIFETIME skiing holiday - what could possibly go wrong?!Amber has seen the light and returned to the QUEENS OF EIGHT GREEN. PHEW! And now she s invited Lottie on her family skiing holiday RESULT!One tiny problem . .. Lottie s never been skiing before and she doesn t know her piste from her poles! How hard can it be though?Join Lottie as she learns how to ski with old and new friends, tries fondue for the first time and discovers what the banana of destiny has in store for her.Will this be the best holiday ever or is it all downhill from here?Readers LOVE Lottie Brooks:My daughter couldn't put it down and read it in 2 days. Read at breakfast, walking downstairs, tea time, in the bath.My 9-year-old daughter devoured it in two nights, and all I could hear from her was gigglin

The third mystery about intrepid adventurer, Amelia Cheeseheart and her sidekick Webster, who solve an icy mystery in the museum!Amelia and Webster are going camping in the Ice Age exhibit, but when they arrive, they discover that all the cave mice have disappeared. Then the bellow of a terrifying beast scares Webster away in a terrible panic! Desperate to find him, Amelia enlists the help of famous mouse adventurer Stilton Jones, and together they agree... it's time to investigate!

A vacation in paradise turns deadly when four teens' sailing charter hits stormy seas in this propulsive new thriller from New York Times and USA Today bestselling author Megan Lally!Hannah can't wait to spend spring break with her best friend, Emmy, and her family. A week at a resort in Mexico is going to be fantastic de-stressing from senior year, not to mention Hannah's been crushing on Emmy's brother for as long as she can remember. Maybe he'll finally notice her. That would be paradise...The beach is gorgeous, except Jackson always has his nose in a book and Emmy meets a guy. Hannah can't help but feel like a third wheel. When Emmy's new boyfriend charters a catamaran, Hannah and Jackson are invited along for the day. Hannah still has hope for a windswept kiss.As the clouds roll in and the skies darken, their boat is the only one leaving the marina. And the further they get into open water, the more Hannah doubts their captain's--and Emmy's boyfriend's--intentions. Something's not

A new reign is coming...Romance, magic, adventure, and horror collide in the start to this lush, epic, Ancient Egyptian inspired trilogy perfect for fans of Leigh Bardugo, Tahereh Mafi, and Sabaa Tahir.Princess. Priestess. Rebel. Thief. Tensions run as hot as the Khamsin winds in the great kingdom of Khetara. Rumors of the pharaoh's mysterious illness abound, and with them, murmurs of rebellion grow. Meanwhile, in the quiet desert, a forgotten oracle begins to unfold, setting a dark prophecy into action and drawing together four strangers...Princess SITA lives in the abundance of the palace, and in a moment of passion, she unmasks a betrayal that will put her life--and the entire royal court--in grave danger.A priestess-in-training, NEFF strives to understand her intense visions from the gods, except theirs is not the only magic at play in the grand temple.As a farmer's daughter, RAE knows how much the pharaoh's men have taken from her land, her people. Still, who will step forward to

WINNER OF THE BOOKER PRIZE 2025, David Szalay’s captivating and astonishingly moving novel about the forces that make and break our lives**WINNER OF THE BOOKER PRIZE 2025**‘Brilliant and wise on chance, love, sex, money’David Nicholls‘I was tearing through [Flesh], I never once slowed down’Jennette McCurdy‘Brilliance on every page’Samantha Harvey‘So much searing insight into the way we live now’ObserverThrough chance, luck and choice, one man’s life takes him from a modest apartment in Hungary to the elite society of London – in this captivating new novel about the forces that make and break our livesFifteen-year-old István lives with his mother in a quiet apartment complex in Hungary. New to the town and shy, he becomes isolated, with his neighbour – a married woman – as his only companion. When a clandestine relationship begins between them, his life spirals out of control.As the years pass, István moves from the army to the circles of London’s elite. His competing impulses for love,

深受家長與老師信賴的美國教育品牌Brain Quest，全新推出可擦寫系列第二冊《ABC 字母學習》。本書專為早期學習階段設計，協助孩子建立字母辨識、正確筆順與精細動作控制能力，是進入正式書寫前的重要基礎。每一頁兼顧練習與趣味活動，透過鮮明插圖與標準化課程設計，讓孩子在描寫大小寫字母的同時，也強化觀察力與專注力。字母皆附指引點與箭頭，幫助孩子掌握正確書寫方向。可擦寫頁面搭配雙面可拆式白板與乾擦筆，提供反覆練習的彈性。頁末設計互動式問題，鼓勵家長陪伴討論，延伸語言與思考能力。銜接前作《Preschool Skills》，打造完整學前學習路徑，是在家共學與幼兒園補充教材的理想選擇。Who's ready to write? The second title in Brain Quest's new write-and-erase workbook line introduces children to the alphabet with tons of writing practice and curriculum-based ABC activities to build pre-literacy and fine-motor skills. Wipe clean pages and included dry erase marker means kids can have fun over and over and over again! Brain Quest Write and Erase: Alphabet Skills introduces children to the alphabet, providing essential practice in letter recognition, writing, and fine motor skills for early learners. Includes a removable double-sided white board and dry erase marker (attached in spiral binding). Discover the joy of learning with Brain Quest! From the brand that's loved by kids, teac

An official Minecraft manga adventure! Peaceful life in a perfectly constructed town bores ten-year-old Nico into mischief. Riding Creepers while they explode is fun and all, but what he really wants is to escape the blocky confines of his home and take his crafting skills on an adventure to the ends of the world. Just how big is the world, anyway, and what could possibly stand in his way? Nico has made it! Finally, he and his friends have set foot in the Nether. But, wait...what are all these enemies doing? How did Nico get surrounded? Nico and his incredible ability to create MODs are really going to be put to the test now!

This is a dialogue across East and West,and a sincere remembrance of trust, responsibility, and mission.From classroom to life, from ideas to practice,the book records not only Drucker’s thought,but the legacy of a belief at its core:that management exists to develop human beings.In 1999, Peter Drucker, the father of modern management, embarked on a profound dialogue with Chinese entrepreneur Shao Minglo over a shared vision for education. Drucker made a solemn commitment: to serve as Shao’s pro bono advisor for the rest of his life. In the years that followed, the two met regularly in California to discuss management education in China, economic realities, and organizational culture—forging a deep friendship that transcended both culture and age.This book records that precious journey. It illustrates not only how Drucker translated ideas into practice, but also portrays his sincerity, warmth, and humanity. He held a deep hope for the future of management in China, remained steadfast i

Dante is back in Camp Catastrophe, the second in this hilarious, highly illustrated series for children aged 7+, by author/illustrator Brian Gordon. Perfect for fans of Diary of a Wimpy Kid. After winning their school quiz, Dante and Virgil are ready for a rest.But when Virgil suggests they go to Camp Sulphur Springs, Dante reluctantly agrees. What could possibly go wrong?A LOT! Endless rain, sharing a cabin with his nemesis and being hit in the butt by a stray arrow are only the beginning of Dante's woes. With an outrageously annoying heartthrob camp counsellor and whisperings of a monster lurking in the woods, Dante’s problems are about to get MUCH worse!Follow more of Dante's adventures in Dante N.Ferno is NOT a Loser.

一本顛覆傳統，漫畫、劇本式直白呈現從無到有寫論文、期刊發表的歷程專書，教你寫出好論文……論文寫作就是一項闇黑的試煉。期待每位撰寫者在闇黑中找出屬於自己的那一道光。——國立屏東大學校長 陳永森教授應該不要只糾正學生寫作，而是應關心學生寫作的「心路歷程」。——普立茲獎得主、新罕布什爾大學教授唐納德‧默里繼《闇黑研究方法》後，作者方偉達又一「闇黑」力作！搭配精采漫畫故事，這次，又會讓讀者見識到怎樣的「闇黑」境界呢？將軍的戰場在戰場，教授的戰場在講堂。──方偉達 對每位研究者而言，論文是取得學位、職位升等……的門檻，如何在論文進行之初，就對論文寫作與研究方法擁有基礎的認知是基本功，但這也往往最讓撰寫者感到煎熬。 這一本書，不是只談枯燥的論文寫作過程、英文的修辭、文本進行修改，以及糾正錯誤的無聊書寫，它還著重在寫論文時，從無到有撰寫者擬真的心路歷程。透過書中12個角色人物，漫畫劇本中生動的演繹、呈現，讓寫論文的想題目、著手寫（研究課題、研究方法、參考文獻、研究設計、資料收集、分析討論……等）原本枯燥、制式的「程序」動作，讓你不只是理論、實務具備，更能在作品發表時，獲得你自己專屬的學術生命養成與智慧回饋。本書精彩篇目：PART 1西遊記什麼是論文、瞭解您的名詞：博士不只一種、論文開始前入門整理、科學在於不斷的證明、學校不會教您論文的格式、如何開始寫學位論文的摘要、表格和數字要怎麼列、如何寫學位論文的結論與建議、打造一些新的觀點和論述……PART 2封神榜沉浸在思考享受的過程、您的引用的來源可靠嗎、哈佛教會我的論文改寫方法、為什麼不能重複自己的話、學術論文的誠信、跨國國際出版商賣掉您的智慧財產權、論文要開放資訊（Open Data）嗎、發表文章被引用很重要嗎……書末附上碩 (博)士論文/書面報告/技術報告/專業實務報告通過簽名表、解釋名詞、貢獻者角色分類法

Read about the origin stories of Addie and Keedie in this incredible prequel toA Kind of Spark.Set in Juniper five years beforeA Kind of Sparkcomes a powerful coming-of-age story from award-winning author Elle McNicoll.As Keedie and her twin Nina approach their fourteenth birthday, they seem to only be growing further apart. Keedie instead feels drawn to, and fiercely protective of, their quiet younger sister Addie – who on the surface is the opposite of loud and fiery Keedie, but in fact they have more in common than anyone knows.'This is a novel filled with love - not only Keedie’s love for Addie but McNicoll’s for young neurodivergent people everywhere, and the brilliant and brave Keedie will inspire those children to be proud of who they are'The Bookseller'A brilliant story of kindness, justice and just a little bit of revenge. Brash, bold and furious, just like Keedie herself' Lizzie Huxley-JonesDon't miss Elle McNicoll's other books for young readers:A Kind of SparkShow Us Who Yo

Shortlisted for the UKLA Book Award 2022 ages 7-10 | Winner of the Blue Peter Book Awards 2021, Best Story | Shortlisted for the 2021 Branford Boase | Award Shortlisted for the Little Rebels Award 2021Elle McNicoll's heartfelt and relatable debut is sure to spark courage in its readers for years to come.AS SEEN ON BBC TVWINNER OF THE WATERSTONES BEST BOOK FOR YOUNGER READERS AND OVERALL WINNER 2021WINNER OF THE BLUE PETER PRIZE FOR BEST STORY 2021A Kind of Spark tells the story of eleven-year-old Addie as she campaigns for a memorial in memory of the witch trials that took place in her Scottish hometown. Addie knows there's more to the story of these 'witches', just like there is more to hers. Can Addie challenge how the people in her town see her, and her autism, and make her voice heard?A story about friendship, courage and self-belief, perfect for fans of The Goldfish Boy.'A remarkable debut' The Sunday Times: Book of the Week'Definitive and funny' Susin Nielsen'A fabulous, brillian

Build skyward in this graphic novel set in the world of Minecraft! It takes teamwork to adventure across the world of Minecraft, and that's something brothers Cobb and Flint don't have. But when their young friend, Rochelle, heads off on her own into a monster-infested zone, the two must work together to try and find her before some nasty beast does. Cobb considers himself a simple farmer and, until recently, a bit of a loner. He's content to mind his crops, gather resources, and be left alone. But fate has more in store for Cobb than intercepting the wayward villagers who replace his carrots with potatoes! When a mysterious treasure map captures the imagination of Cobb's young friend Rochelle, she tries to inspire his adventurous side. But when Cobb refuses to join her, Rochelle decides to follow the map all on her own--leaving Cobb a copy in case he changes his mind. Sure enough, Cobb is thrust into action when his adventure-obsessed brother, Flint, points out that the map leads stra

Follow twelve-year-old Sim's time travel adventure in Ancient Rome in The Impossible Gladiator, the third title in Time Keys, a bestselling spectacular, action-packed mystery series by multi-award-winning author M. G. Leonard.'A complete triumph of imagination . . . readers are going to fall in love with this brilliant series' — A. F. Steadman, bestselling author of Skandar'A captivating adventure loaded with history and intrigue' – Abi Elphinstone''A cracking series with stunning illustrations' – Christopher Edge, bestselling author of Escape RoomThe action adventure of Gladiator meets the time travel of Doctor Who in the third title of this epic series by bestselling award-winner M. G. Leonard. Perfect for 8 to 12-year-old fans of Adventures on Trains. Supports the curriculum. Illustrated throughout in black and white by Manuel Šumberac.Sim, Jeopardy and Nelson are enjoying an amazing holiday in Rome, until they they are swept up in the mysterious disappearance of world-famous illusi

Meet Suki Cat - an adorable preschool character starring in a series of action-packed stories with easy-to-use sliders!Who will Suki be today? Peek inside the box and play! Toddlers will love discovering who Suki Cat will become at the start of each story, before joining in with her dressing-up adventure - where she always saves the day!In Firefighter, Suki Cat puts on her uniform and is ready for action! When the alarm bell rings, the firefighters are called out for an emergency but will Suki be able to help?From astronaut to dinosaur, this interactive series of vibrant board books with robust mechanisms is perfect for developing motor skills and inspiring imaginative play.Toddlers will enjoy pushing, pulling and turning the chunky sliders to take part in the story and bring the action to life! The narrative-driven, rhyming text is perfect for reading aloud to help build book confidence and engagement, while the high level of interaction develops gross and fine motor skills.Other titl

Big ideas for curious minds are simply explained in this fascinating first introduction to artificial intelligence.Who invented the first artificial intelligence? How do machines listen without ears? And can I use artificial intelligence to talk to my pets?Learn what artificial intelligence is and how it works as you explore its impact on the environment, society and even our own bodies.Discover how artificial intelligence is used all around you, from smartphones and search engines to cars and prosthetic limbs, and how it might be used in the future!Fun, conversational text breaks down complex ideas so they are accessible to young readers.Created in consultation with experts from the University of Cambridge.Colourful and dynamic illustrations bring abstract concepts to life.For more big ideas, don't miss other titles in the series:Think Big: Secrets of BeesThink Big: The Speed of Light

A spellbinding story about a little girl, the sea and a seemingly fierce creature in need of her help – perfect for fans of Benji Davies' The Storm Whale.My toes hunt for grooves in the rock. And then ... I see her. While searching for wonders in the rockpools, a little girl discovers a silver shark, stranded in the shallows – sleek and quick, but still just a baby. The sun is high and the tide is out: how will the shark find its way home? Drawing on family memories of life in Barbados, award-winning author Mariesa Dulak and bestselling artist Alea Marley have woven together a spellbindingly beautiful story about our connections to the sea, and what we owe other living creatures.

Discover prehistoric animal battles in this exciting bindup featuring four action-packed Who Would Win? books! Which prehistoric creatures would win in a head-to-head battle? What if there was a dinosaur tournament? Which pterosaur will be the champion?Find out all this and more in this awesome bind-up of four books in the popular Who Would Win? series. The collection features a range of prehistoric battles to satisfy all kinds of dinosaur fans, including Triceratops vs. Spinosaurus, Tyrannosaurus Rex vs. Velociraptor, Ultimate Pterosaur Rumble, and Ultimate Dinosaur Rumble.Kids will learn about each animal's anatomy, behavior, and more alongside photos, charts, illustrations, and amazing facts.

A vividly rendered graphic novel adaptation of Lauren Tarshis's bestsellingI Survived the California Wildfires, 2018, with text adapted by Georgia Ball and art by Cassie Anderson.All across California, deadly wildfires rage . . .Still reeling from the life-changing challenges that propelled him and his mother across the country, Josh finds solace in the California wilderness and in the newfound friendship with his cousin Holly.But on a trip into the nearby forest, Josh and Holly suddenly find themselves in the middle of a frighteningly powerful firestorm, one which threatens to burn down everything in its path. Josh needs to confront the family issues burning him up inside, but first he'll have to survive the flames roaring all around him.Lauren Tarshis’sNew York Timesbestselling I SURVIVED series blazes to life in this graphic novel edition. Perfect for readers who prefer the graphic novel format, or for existing fans of the I Survived chapter book series, these graphic novels combine

Liv Livingston and her friends are off to a weekend camp retreat in book six of the Spirited graphic chapter book series. Liv Livingston packs for a supernatural weekend getaway at the lake! The van Pires have invited her and Howl to the lake home for campfires, swimming, and spooky tales of what lurks in the forest outside of town. But nothing is ever that simple in the ghostly town of Gloomsdale. Strange footprints surround their campsite. And the lake shifts and bubbles, as if something dwells underneath...ready to surface.

Serendipity is the luckiest kid in the world. But what happens when the luckiest kid in the world becomes extraordinarily unlucky, in this debut graphic novel. Serendipity is your classic overachiever. She's class president, lead in the school play, and star of the basketball team. She's also incredibly lucky, like, wins everything all the time lucky, even random radio raffles. Which is how she finds herself with free tickets to the town carnival where an accident curses her with bad luck FOREVER. And just like that Serendipity's luck really does seem to run out. Missed shots, fumbled lines, and a slip in the polls. Can it get any worse? Oh yes it can. Permanent bad hair days. Serendipity becomes convinced the curse is real. She's definitely not disorganized or spread too thin. Nope, it's all the curse. And she'll have to find a way to reverse it soon. Hilariously charming and illustrated in sugar pink hues, this graphic novel is a treat for kids who love middle school dramas and adora

臨床療效是醫學的生命。離開臨床無醫學。了解醫學之演變與應用，對於臨床診療的實際，將有更深入的理解。 本書《臨床與基礎醫學交會之今昔》，由陳麒方、皮國立兩位教授學者主編，共收錄8篇文章以及1篇中醫臨床醫學雜誌論文總清單。文章作者群涵蓋醫藥衛生領域16位專家學者，文章主題包含：中醫癌症診治分析、婦幼醫學孕產用藥與轉骨探討、台灣系統化醫療肇始（日本時代的醫生免許規則等）、傳統醫藥領域的新技術肌筋膜脈學治療及其醫案、醫學書翻譯的研討等。另有目前發行時間最長的台灣中醫藥期刊《中臨醫誌》論文總清單920篇完整書目。本書對臨床醫學以及基礎醫學從治療、藥品、醫學演變、技術、文化發展等面向，都有論述，是一部相當有意義的中醫學術書。 This book ""On the Interaction of Clinical and Basic Medicine"" is edited by two scholars, Prof./Dr. CHEN Chi-Fang and Prof. PI Kuo-Li. It contains a total of 8 articles and a comprehensive list of articles in Taiwan Journal of Clinical Chinese Medicine (TJCCM). Group of the article covers 16 experts and scholars in the field of health from whole Taiwan. The topics of the article including: Exploring the Relationship between Dysfunction of the Four Major Functions of the Human Body from the Perspective of Traditional Chinese Medicine and the Occurrence of Cancer, Research on the Safety of CM usage during Pregnancy, Development of CM Bone-Strengthening Formulae, Japanese-Ruled

本書以淺顯易懂的方式引領讀者踏入AI世界，從Google AI實驗室的趣味體驗入手，破除「需懂程式才能學AI」的門檻。透過影像、聲音、語言等多元應用實例，逐步建立對人工智慧的基本認識與正向期待。全新增訂的第8章更深入生成式AI浪潮，解析LLM、提示詞、多模態等關鍵概念，並導覽Gemini、NotebookLM等當代工具，帶領讀者從「體驗AI」走向「動手創作」，開啟人機協作的新可能，攜手迎接屬於每個人的科技奇點。‧ 只需開啟瀏覽器即可在手機、平板或電腦操作。‧ 圖文說明精彩、操作畫面介紹流暢，實際演練人工智慧的網路應用。‧ 從淺到深的人工智慧教學內容，使初學者可以快速上手。‧ 新增Google AI生態系：Gemini、NotebookLM、AI Studio與Google Labs的介紹。

從財商 R.I.C.H出發走向複利人生理財，像種一棵生命樹。Ｒ──重構思維（Reframe）你得先知道，這棵樹要怎樣才能真正長高，才能在風雨來時，有地方遮蔭。心態是根，根不穩，樹就會倒。Ｉ──收入（Income）你種出來的果實，不是用來一口氣吃光。一部分要拿來養自己，一部分要留起來，為冬天做準備。你的果實要能夠保存，也要知道放在哪裡，才不會被偷走。Ｃ──放大資本（Capital）當你有了一籃健康的果實，就該學會「種出果實的種子」，讓每一顆果實，都有可能長出一棵新的樹。Ｈ──收穫人生（Harvest）當你的林子越來越大，你終於不用追著錢跑。你可以選擇自己想過的生活節奏，有時間、有選擇，也有餘裕去看風景。這才是理財最終的意義。理財，不只是財務的成長，更是生命的修行。從心出發，從根開始。慢慢種，總有一天，你會在自己的樹蔭下乘涼。

Henry doesn't think anyone appreciates his unusual art, but one night everything changes... Henry is an artist, a master sculptor and . . . a dog. Unfortunately, his self-made pieces, in all their sculptural forms, are often tossed in the bin without even being noticed! But Henry never gives up on his art until, one day, an unexpected somebody finally falls in love with his work and at last Henry has his moment to shine.