Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Friendship is one of life’s greatest gifts – and one of its most important skills! As Little Brown Bear knows, having a friend to rely on makes all the difference in the world. But in order to have go

包含1000個與STEM相關的名詞、動詞和形容詞，幫助孩子理解重要的科學概念同時擴充詞彙量，是孩子開始STEM教育的好幫手。· 科學主題多元化，豐富孩子的詞彙量。· 激發孩子思考、說話和早期科學技能。· 豐富精美的插圖，圖文並茂解釋字詞。幫助孩子探索科學概念，擴充中英科學詞彙量！這本書會是孩子開始STEM教育的好幫手。孩子開始在學校剛學習STEM的初期，可能會遇到很多新的單詞。STEM課程中會使用大量的術語：科學儀器的名稱，無形東西的名稱（例如力），以及描述物料特定屬性的名詞（例如「不透明的」），這些對孩子來說都是全新的事物。本書包含孩子在入學首數年可能會遇到的主題和詞語，也包含了許多令孩子着迷的主題，以及一些在我們日常生活中會碰到的STEM主題。l 包含各種與STEM相關的名詞、動詞和形容詞，幫助孩子理解重要的科學概念。l 29個和STEM相關的主題，由聲音、人體、生態系統，以至天氣、數量計算、機械等，豐富孩子的科學詞彙量，提高孩子的閱讀和寫作能力。l 書中設有各種趣味提問，讓孩子在頁面上尋找答案，啟發他們思考及討論，有助發展語言能力。本書的1000個詞彙共分為29個主題，包括l Hot and cold熱和冷l Seasons季節l Sound聲音l Machines機械l Space太空l Moon landing登陸月球l Transport交通工具l Vehicles運輸工具l Weather天氣l At the doctor's看醫生l Human body人體l Materials物料l Underground在地底下l Comparisons比較l Junk廢料l Measuring量度l Up high在高處l Long ago在很久以前l Plants植物l Playground forces遊樂場的力學l Laboratory在實驗室裏l Ecosystems生態系統l Classification of animals動物分類l Water水l Experiments實驗l Mixing and cooking混合與烹飪l Light光l Adding and subtracting加和減l Sharing and grouping分享及分組

This is a story which begins in California and ends in China. It is a detective tale with a subtle love interest. Victor Lin, a Chinese-American died in mysterious circumstances on a trip to the Thous

Peep under seaweed and waves and into rock pools to discover all the delights of the seashore in this little book. What does a limpet look like in its shell? What's inside a pelican's bulging beak? Wh

What's in your body?Have you ever been shown?That you have a skeleton,made up of... BONES!Tug the tab to reveal all that hides in your insides. From nose to toes, there's plenty to discover with the m

The first book in the Bevelstoke series: witty, irresistibly romantic and by the bestselling author of the global phenomenon Bridgerton'2nd March 1810 . . .Today, I fell in love'At the age of ten, Mis

初學者能夠輕鬆學習實作Android的過程 精選5大主題循序漸進讓你簡單操作 詳盡的步驟圖文解說內容快速上手 本書內容改編自第11屆iT邦幫忙鐵人賽Mobile Development組佳作，以「iOS的角度」去撰寫，用筆記的形式做紀錄，並輔以獨立的小範例做說明。書中的程式語言是使用Java進行開發，重點在Android的畫面與功能上的應用。 【本書精彩內容】 入門篇：介紹開發環境、專案設定、基本

Historical monarchs are interviewed from the grave in this hilarious children’s graphic novel.Discover the incredible stories of rulers throughout history in this hilarious graphic novel that brings t

In his penultimate adventure, now in paperback, a devastated but determined Apollo travels to Camp Jupiter, where he must learn what it is to be a hero, or die trying."A clash of mythic intrigues and

Get ready for action, adrenaline and adventure in the latest explosive Alex Rider mission by bestselling author Anthony Horowitz, now in paperback. In this adrenaline-fuelled adventure in the number o

A funny story, all about wee, packed full of animal facts! The follow-up to the hilarious Poo! Is That You?Lenny the lemur is on holiday in Alaska. He's skipping across the snow, when he slips in a pu

A brilliantly fun search-and-find puzzle book for children from 6+, developed in consultation with the British Museum. Tom's not only lost in time, he's lost his cat, too! Can you find Tom and his n

Now in hardcover for the first time, featuring new illustrations Return to the world of the Wingfeather Saga with Andrew Peterson and his all-star author friends. Immerse yourself in a land of bomnubb

A brand new title from award-winning Marta Altes. This dog may be alone and without a home, but he's excited and ready to embrace a new life in a new town - and EVERYONE in it! This town is a busy, vi

Winnie and Wilbur are visiting the wild animals from their library book in real life. It's exciting to journey by magic all around the world, but there is trouble for our travellers when the animals get hungry! A whistle-stop tour full of hilarious slapstick fun, with plenty of details to pore over in Korky Paul's intricate and spellbinding artwork. The best-selling Winnie and Wilbur series has been delighting readers both young and old since 1987 and Winnie and Wilbur have become favourite characters in homes and schools all over the world.

The dolls love travelling the world in their girl band. Use the stickers to dress them for a dance rehearsal, a day in the recording studio, a big performance and their jet-setting world tour. With ov

Longlisted for Blue Peter Book Awards 2022Dive into the weird and wonderful world of sleep, from the science behind dreams to a peek into animal sleeping habits, in this incredible book for children aged 7 to 9. We spend about 26 years of our lives sleeping, but how much do you really know about what happens when your head hits the pillow? Flick through the charming illustrated pages and discover:- What is sleep, and why do we need it?- Who's still awake across the globe when you are tucked up in bed?- The history of sleep, including the evolution of the bed and the significance of dreams in myths and legends- How does sleep differ in the animal kingdom? From polyphasic sleeping lions and nocturnal raccoons to birds high in the sky and whales in the ocean- What happens to plants when the sun sets?- Practical tips and tricks to help you improve your bedtime routineThe Magic of Sleep answers all your questions about what goes on in your head when you snooze, including the difference betw

Join the busy farmer in this playful, interactive flap book!It's a busy day on the farm! Join in and use the flaps to help the farmer collect the eggs, harvest the crops, milk the cow and much, much m

Join in and help the busy firefighter in this playful, interactive flap book!Nee-naw, nee-naw! Can you help the firefighter to save the day? Join in and use the flaps to slide down the pole, unroll th

With questions such as How do you write a song? and Can you play music in space? this book is perfect for encouraging an interest in music. Lift the flaps to discover instruments from around the world, and hear them come to life by listening to the book's playlist on Usborne.

Little Bear, Little Monkey, and their friends love to use a pacifier. But sometimes it gets in the way when they play, talk, or go outside. In this reassuring book, the grown-ups show them that giving

The seventh novel in Julia Quinn's globally beloved and bestselling Bridgerton Family series, set in Regency times and now a series created by Shonda Rhimes for Netflix. This is Hyacinth's story: she'

Since he crash-landed to Earth in a rocket, Monkey has been causing absolute mayhem! Bunny and the gang (Squirrel, Pig [the Pig], Action Beaver, and Skunky the Inventor) have almost had enough. In this rollicking comic extravaganza, the pint-sized friends must tackle a helliphant, rocket-powered hot air balloons, and the most mind-boggling creatures of all . .. hew-mans . .. Jamie's art and storytelling fizz with exuberance - the pages turn themselves in this addictive collection of stories.

Rafe Khatchadorian is back in the latest adventure in the bestselling Middle School seriesThings have quietened down for lovable troublemaker Rafe Khatchadorian, and after all the mishaps and adventur

The perfect story to remind children about the importance of kindness. 3, 2, 1, go!Ned the hamster has been in training for the Great Garden Hamster Race but when race day arrives, the route is cluttered with critters in need of help. Will he realise that a few small acts of kindness are more important than winning at any cost?This positive picture book from author/illustrator Kim Hillyard will inspire all readers big and small to look up and offer help to those who might need it.Also available from Kim Hillyard:Mabel and the Mountain: a story about believing in yourself

Hilarious, illustrated school-based antics where everything that happens leads to DRAMA and RUNNING AROUND and even some FAINTING!When a session of extreme dancing leaves Maisie in hospital with a broken leg, things take a turn for the weird! Strange noises in the ward at night, missing cuddly toys and a sandwich trolley that only ever has TUNA sandwiches. Could Maisie’s leg be CURSED? If it is, and it DEFINITELY IS, then everything is DOOMED!Laugh-out-loud fun from Blue Peter Award winners Pamela Butchart and Thomas Flintham.Read more of Izzy’s adventures!Baby Aliens Got My TeacherThe Spy Who Loved School DinnersMy Headteacher Is a Vampire RatAttack of the Demon Dinner LadiesTo Wee Or Not To Wee!There’s a Werewolf In My Tent!The Phantom Lollipop Man!There’s a Yeti in the Playground!Icarus Was Ridiculous

Peep under flaps and through holes to explore the snowiest places on Earth in this little wintry book. Peep under the snow to see polar bear cubs coming out of their den, seals and narwhals in the icy

Lara Jean’s letter-writing days aren’t over in this follow-up to the bestselling To All the Boys I’ve Loved Before and P.S. I Still Love You. Soon to be a major motion picture coming to Netflix in 202

An action-packed comedy about a fake family that includes a spy, an assassin and a telepath Master spy Twilight is unparalleled when it comes to going undercover on dangerous missions for the betterment of the world. But when he receives the ultimate assignment--to get married and have a kid--he may finally be in over his head Twilight has overcome many challenges in putting together the Forger family, but now all his hard work might come undone when Yor's younger brother Yuri pops in for a surprise visit Can Twilight outsmart Yuri, who actually works for the Ostanian secret service?

Return to the world of dragons, Fae and Librarian spies in this action-packed instalment of the Invisible Library series. Librarian-spy Irene finds herself in hot water, as a mysterious killer pursues

In twenty years behind the till in The Bookshop, Wigtown, Shaun Bythell has met pretty much every kind of customer there is - from the charming, erudite and deep-pocketed to the eccentric, flatulent a

A world of enchanted injustice needs a disenchanting woman in an all-new fantasy series by the Wall Street Journal bestselling author of The Paper Magician.The orphaned Elsie Camden learned as a girl that there were two kinds of wizards in the world: those who pay for the power to cast spells and those, like her, born with the ability to break them. But as an unlicensed magic user, her gift is a crime. Commissioned by an underground group known as the Cowls, Elsie uses her spellbreaking to push back against the aristocrats and help the common man. She always did love the tale of Robin Hood.Elite magic user Bacchus Kelsey is one elusive spell away from his mastership when he catches Elsie breaking an enchantment. To protect her secret, Elsie strikes a bargain. She’ll help Bacchus fix unruly spells around his estate if he doesn’t turn her in. Working together, Elsie’s trust in—and fondness for—the handsome stranger grows. So does her trepidation about the rise in the murde

In this momentous 50th book in the critically acclaimed, multimillion-copy bestselling Little People, BIG DREAMS series, discover the life of Elton John, the piano wizard who rocketed to stardom with

別被他可愛的外表騙了──這隻貓可是練過「Kat Fu」的都市傳奇英雄！《Cat Ninja》第1集揭開Claude的雙面生活：一方面是男孩的寵物貓，另一方面是面對壞蛋、機器人和住家老鼠對手時的超級忍者。本書以漫畫形式呈現，圖像與文字比例適中，適合剛轉換至長篇閱讀的小讀者。劇情融合了英雄故事的架構與家庭幽默，讓讀者在歡笑與冒險中了解「英雄」也可以是你家客廳裡的一隻貓。喜愛《Dog Man》或《Narwhal and Jelly》的讀者也會輕鬆上手。Beware, villains! Cat Ninja may appear to be nothing more than a silly internet meme. But he is evil's greatest enemy, and the silent master of Kat Fu and carpet scratching! From Epic! Originals, Cat Ninja is a hilarious graphic novel series about a lovable cat with a heroic alter-ego.Raised from a kitten by a kindly old ninja master, Claude now spends his days as the pampered house cat of an eleven-year-old boy. But when trouble arises, Claude dons his mask and springs into action as Cat Ninja―Metro City's secret protector! In Book 1 of the series, follow our feline hero’s early exploits as he tries to keep his secret identity under wraps while thwarting the evil plans of slimy thugs, rampaging robots, and a certain rodent nemesis who lives under the same roof!

聯合國教科文組織所屬國際文化紀念物與歷史場所委員會(ICOMOS)荷蘭國家委員會與臺灣水利環境科技研究發展教育基金會(TIIWE)聯手於2019年5月27日至29日期間，在臺灣舉辦全球首屆「2019水文化國際研討會(2019 International Conference 'Water as Heritage')」，本局將研討會各主題投稿文件，進行蒐集及彙整，集結成冊出版英文版論文集，以推廣分享

只有不斷實際應考，才能掌握新制多益的出題趨勢！由日本多益教學專業團隊領軍，實際應考超過1000次多益測驗，分析出題趨勢和解題關鍵，破解990高分的祕密！Essence English School是日本第一的多益專門校，教學團隊每月進場，累積超過1000次以上的應考經驗，完全掌握多益的出題方向與陷阱，多年來已協助許多不同程度的考生，取得大幅進步的成績。為造福更多考生，結合師資團隊經驗與精準出題方向

What’s the Time in London? Find out in this adorable clock book! With a real clock face for children to practise telling the time, this soft-learning book gently teaches children about the hours of th

Longlisted for Blue Peter Book Awards 2022Imagination and adventure run wild in the most talked about middle grade debut of the year!A small village on a Jamaican island.A girl who doesn't remember the previous summer.A best friend who is no longer acting like one; a new girl who fills that hole in her heart.A summer of finding fallen mangos, creating made up games and dancing in the rain.Secrets she keeps from others...and herself.The courage to face the truth even in the toughest of storms.Inspired by the author's childhood experiences, When Life Give You Mangos is a celebration of island life as well as a rich, lyrical mystery.Read it...and don't spoil the unforgettable ending!A recommended read for classroom discussons and educators looking for diverse offerings. A wonderful story with great heart, mystery, and insight. Kereen Getten is a bright new voice. --Clare Vanderpool, author of Newbery Medal winner Moon Over Manifest and Printz Honor book Navigating EarlyA heartwarming

只有不斷實際應考，才能掌握新制多益的出題趨勢！由日本多益教學專業團隊領軍，實際應考超過1000次多益測驗，分析出題趨勢和解題關鍵，破解990高分的祕密！Essence English School是日本第一的多益專門校，教學團隊每月進場，累積超過1000次以上的應考經驗，完全掌握多益的出題方向與陷阱，多年來已協助許多不同程度的考生，取得大幅進步的成績。為造福更多考生，結合師資團隊經驗與精準出題方向

'There's something I need you to help me with. When I say BOO, you say HOO. Are you ready?' Boo is little ghost who lives in a haunted house - and he is afraid of the dark. In I Say Boo, You Say Hoo,