Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Melissa Cookston, the "winningest" woman in barbecue and author of Smokin' in the Boys' Room, is bringing the heat with her second cookbook that explores the cultural flavors that ha

本書描寫一位小女孩親手打造自己的娃娃屋，從外牆的磚紋、室內的壁紙，到替娃娃縫製的衣服，甚至用紙杯做成的小小電梯，每個細節都來自她的想像與雙手。她對這座獨一無二的家感到驕傲，也在其中玩得不亦樂乎。直到有一天，她看見朋友 Sophie 那棟「完美」的現成娃娃屋——所有配件一應俱全，連馬桶蓋都能掀起。兩人一番比較之後，逐漸發現，真正好玩的並不是什麼都齊備，而是能自由改造、反覆想像的空間。A girl makes her own dollhouse in this picture book that celebrates creativity and imagination!A little girl proudly walks the reader through her handmade dollhouse, pointing out the bricks she painted on the outside, the wallpaper she drew on the inside, the fancy clothes she made for her dolls, and the little elevator she made out of a paper cup. She’s proud of her house and has lots of fun using her imagination to play with it—until she discovers her friend Sophie’s “perfect” storebought house. Sophie thinks her house, with everything matching and even a toilet seat that goes up and down, is pretty perfect too, until both girls discover that the narrator’s handmade dollhouse is really a lot more fun."Celebrates the best of free play, capturing what it's like to be fully engaged and inspired." —

Becoming a sinologist means deconstructing stereotypical notions of China’s rise in the twenty-first century. The sinologists in this volume actively think through and adapt to their particular histor

Reading takes many forms. Some of us read novels, while others read cookbooks, sheet music, tarot cards, or even the stars in the sky. We read clocks, train schedules, and facial expressions. In this

Emphasizing the role of local government in regulating and providing employment and social services, political and other social scientists cite three case studies in each of six European countries rep

The paradox confronting us today is that even as we know more and process information at a faster rate, we reason, think, and understand less. While a wealth of literature has been devoted to similar

Have you ever sped past in such a hurry that everything you passed was soft and blurry? And did you ever squeeze your eyes so tight that you saw lots of dots of coloured light? In Did You Ever See? Jo

It’s a rainy day in the month of May and Sam spots a rainbow, and then a puddle. A perfect spring puddle. His mother warns, No! No jumping in puddles! You must keep clean today!” but Sam can’t stop hi

Contributed by law, political science, and other scholars from Europe, Israel, and the US, the 14 chapters in this volume consider policy initiatives in global governance of labor rights, assessment o

In this volume, European law, economics, and political science scholars present 10 chapters that discuss the role of the European Union in addressing global challenges related to poverty, protectionis

Stina, who lives in Iceland, does not like the cold. In fact, she will go to any length to avoid it. Even in summer she never goes out without tights and socks. When winter comes, she hides inside, kn

Into the Snow is an immediate depiction of a child playing, experiencing the sensory joys of winter and independence.Into the Snow is an exuberant story told in the child's own voice. Celebrating immediacy and exploration, along with the tender bond between mother and child, this is a story that feels good, the way all real things do.Masamitsu Saito was born in 1958 in Japan. He studied graphic design at Tama Art University. His work can be found in magazines, on chocolate packages, and inside wonderful books.Yuki Kaneko is an artist, naturalist, translator, and author. She grew up in Japan, and now lives in Brooklyn with her husband and daughter.

DescriptionThe Workplace Success series prepares students for working in an English-speaking job environment. All four English skills-reading, listening, speaking and writing-are included in each unit

Orthopedic surgeons specializing in pediatrics describe surgical procedures in detail and share their insights for the benefit of residents, fellows, general orthopedists, and other pediatric orthoped

Once upon a time there was a little girl called Fiona who lived in Dublin. But Dublin is full of colourful characters and creatures from the fairytale realm. Often not seen or heard, they reside in so

The global expansion of judicial powers makes no exception to Asia. Most noticeable is the judicial expansion in tandem with unprecedented political and legal reforms that have occurred in the two Asi

Three smart, playful, original TED books from a leading architect, designer, and writer in one collection—The Art of Stillness,The Future of Architecture in 100 Buildings, and Judge This—inspire a mor

This volume provides the first comparative survey of the relations between the two most active book worlds in Eurasia between 1450 and 1850. Prominent scholars in book history explore different approa

A thrilling collection of twenty stories - some brand new, some published in magazines, all entirely brilliant and assembled in one book for the first time - with a wonderful bonus: in addition to his

Youth subculture in twentieth-century Britain was a unique phenomenon. Throughout the decades, young people sought to define themselves sartorially, reflecting their identity in terms of regionalism,

Mr. and Mrs. Eiffel are a happy couple enjoying living in the most romantic city in the world, Paris. Until one day, Mrs. Eiffel begins to feel desperately unwell. The experts are unanimous: the only

Marvel over this exact replica of a miniature book created for Queen Mary’s Dolls’ House by cartoonist Fougasse, in print for the very first time!Written in rhyming text and illustrated in full color,

A vibrant and playful seek-and-find picture book by the acclaimed Swedish artist and designer Laura Ljungkvist, in which the reader uncovers animals hidden in a dazzling array of patterns and colors.

Join Florence the hedgehog and she sets out on a winter adventure in this beautifully illustrated picture book.Winter is approaching, and Florence the hedgehog wants to go outside and play in the wood

There are a lot of things to be afraid of in this world: spiders, the dark, being alone. In this simple, beautifully-crafted picture book, acclaimed author/illustrator Laura Vaccaro Seeger shows that

Charlie Brown never gives up in this sweet retelling of the brand-new Peanutsmovie!The Peanuts gang bursts onto the big screen November 6, 2015 in an all new feature film from Twentieth Century Fox!Ch

For the first time ever some of the most famous names in music, sport and show business have got together for a game of consequences to raise money for the BBC Children in Need Appeal. Each participat

In this fourth and final book in Karel Haye's acclaimed Visitors series, the beloved family of bears gets in another round of adventures as they experience the full enjoyment of a New England autumn,

Real kids make a real difference in their communities in this vibrantly photographed chronicle by George Ancona.George Ancona celebrates the joy of kids giving back. In one after-school program, middl

In times of conflicts and crises, an argument insisting on the humane is commonly heard. In wars, voices demanding a humane treatment of prisoners – as decreed by the Geneva Convention – will be raise

Kendo is the first book in English to provide an in-depth historical, cultural, and political account of the Japanese martial art of swordsmanship, from its beginnings in military training and arcane

Low-dimensional solids are of fundamental interest in materials science due to their anisotropic properties. Written not only for experts in the field, this book explains the important concepts behind

The epic space saga, Star Wars: Revenge of the Sith, is finally retold in the iconic Little Golden Book format! Faced with haunting dreams that his wife, Padme Amidala, is in danger, Anakin Skywalker begins his path to the dark side. Featuring stunning retro illustrations, this book is perfect for Star Wars—and Little Golden Book—fans of all ages!

In Company Third Edition The English course for working professionals In Company 3.0 provides updated and expanded content and builds on the success of previous editions, making it the English

For fans of The Hunger Games, Divergent, and Red Rising comes a gripping sci-fi adventure in which a group of teenagers wake up in a mysterious corridor with no knowledge of who they are or how they g

Max and Bob are old friends. Max helps out in Bob's shop, and in the evenings they go fishing together. Until one summer, when everything changes ...From the winner of the 2013 Crichton Award for Aust

Everyone's favorite penguin--and the star of two best-selling readers in clubs and fairs--is back in another adorable adventure!Tony Baloney is excited. It's Pen Pal Month at school. Tony hopes he and

Set in the same world as The Promise of Amazing, this smart, surprising, and romantic follow-up to Robin Constantine's debut novel follows two New Jersey teens as they become friends and fall in love.

With over 110 million copies of his novels in print, David Baldacci is one of the most widely read storytellers in the world. Now he introduces a startling, original new character: a man with perfect

TED 系列 >> The Terrorist's Son: A Story of Choice >> The Art of Stillness: Adventures in Going Nowhere >> The Mathematics of Love >> The Future of Architecture in 100 Buildings