Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

Refreshingly free of jargon and the abstruse mathematical equations that characterize so many works of a speculative nature, this insightful study utilizes masterworks of twentieth-century music as the bases for discussion and analysis.Analytic Approaches is organized into four units. The first focuses on aspects of musical structure other than pitch, such as rhythm, texture, timbre, form, and relationship of tonal music to the musics of our time. Units 2 and 3 deal with pitch structure: Unit 2 with pitch-class sets and Units 3 with serial music. Unit 4 contains a survey of music of the most recent generation.The author admits freely that the perception of a work of art is a personal matter. In this book, he does not pretend to teach "the" way to listen to or to analyze contemporary music. Rather, he seeks to lead the reader to more informed listening through an understanding of how musical materials are used achieve both sonic and expressive effects.

This volume in the Living with the Shore series provides practical and specific information on the status of the nation’s coast and useful guidelines that enable residents, visitors, and investors to

Smith offers a close study of the rhetorical techniques and powers of persuasion that gave Daniel Webster a uniquely influential voice in the political, legal, and social affairs of the young republic

A comprehensive analysis of the relationship between political judgement, bureaucratic advice and military intelligence in the mismanagement of Britain's Falklands policy. The author argues that the J

Janet Reibstein's mother and two aunts grew up in New Jersey amid a close-knit, extended Jewish family set apart only by a genetic propensity for breast cancer. Over fifty years, the disease claims Ja

Sara Midda's richly illustrated In and Out of the Garden has delighted readers and critics alike: "This is the most gentle of books, a peaceful pastime. The delicacy of Sara Midda's art is enchanting

This first major empirical work on the semiotics of social action goes a long way toward answering substantive, theoretical and pragmatic questions on how codes actually operate in a specific social s

This special supplementary volume contains the proceedings of the Colloquium on Ancient Philosophy held at Oberlin College in 1986. The contributors--including Michael Frede, Jonathan Barnes, Martha C

Greek tragedy, the fountainhead of all western drama, is widely read by students in a variety of disciplines. Segal here presents twenty-nine of the finest modern essays on the plays of Aeschylus, So

In 1895, a 27-year-old journalist named William Allen White returned to his home town of Emporia, Kansas, to edit a little down-at-the-heels newspaper he had just purchased for $3,000. "The new edito

In this elegant study, Walt Whitman's democratic, consensual idealism emerges for the first time as truly central to his poetic achievement. Though Whitman's democratic idealism has often been dismiss

Some fourteen years after its initial publication, this important and influential book, with a new, substantial, and candid introduction by the author, is available in a reasonably priced paperback ed

Reviews structural features and functional activities of neurons; typology and functional role of glia; cellular processes associated with the synthesis of molecules involved in chemical neurotransmis

Are phenomena labeled as corrupt subject to systematic social science investigation, or does corruption lie so much in the eye of the beholder as to frustrate serious analysis? The editors of this vol

Designed as a text for a one semester course to introduce graduate students in mathematics and statistics to the engineering concepts of the discrete Kalman filter and its implications. Annotation cop

In the surprising world that Sami Michael reveals, Shula, an Ashkenazic Jew, is the center of a web of brilliantly drawn characters: Israeli Arabs, Palestinian refugees, “black Jews,” and “white Jews.

This groundbreaking work, first published in 1989, was one of the first to challenge the conventional critical assessment of African literature, and remains highly influential today.Amuta's key argume

This groundbreaking work, first published in 1989, was one of the first to challenge the conventional critical assessment of African literature, and remains highly influential today.Amuta's key argume

Professionals who are on the cutting edge of educational computing discuss, in this provocative new book, one of the most exciting prospects of the field--harnessing the power of the computer to enhan

This advanced textbook on linear algebra and geometry covers a wide range of classical and modern topics. Differing from existing textbooks in approach, the work illustrates the many-sided application

A collection of notes from the seventh and eighth books of Heider's notebooks. Vol. 1 and vol. 3 were reviewed in SciTech Book News v.12 no.3 and v. 12, no.12, respectively. Book 7 covers: measuring,

This comprehensive study, Dai Wangshu: The Life and Poetry of a Chinese Modernist, is one of the most illuminating books on twentieth-century Chinese poetry to have been published in years. It goes be

This volume is intended for professional philosophers and laymen with an interest in East-West studies and comparative philosophy and religion. The central focus is the concept of comparing perspectiv

This book examines this trial of references to cockfighting, beginning in 517 B.C. and extending into modern times. Works by China's famous poets and prose stylists, information from historical, philo

Uses interviews and documents to show how Eisenhower, Kennedy, Nixon, Carter, and Reagan set up their administrations, looks at the politics of appointments, and identifies patterns in the establishme

During the years when modernism triumphed in American architecture, few architects worked more actively to promulgate that vision than Gordon Bunshaft, and none was more adept at translating the ideal

In recent years historians of the American Revolution have become increasingly convinced that political ideas, rather than material interests, were what ultimately led American colonists to fight for

The poems featured in this anthology are quintessentially human documents informed by humor, compassion, and a joyful and visionary elementan impulse to praise what is really life and to protect it fr

The people who live in the Boumaa region of the Fijian island of Taveuni speak a dialect of Fijian that is mutually intelligible with Standard Fijian, the two differing as much perhaps as do the Ameri

This final volume of The Works of William James provides a full record of James's teaching career at Harvard from 1872 to 1907. It includes extensive working notes for lectures in more than twenty cou

Control of the Imaginary was first published in 1989. Minnesota Archive Editions uses digital technology to make long-unavailable books once again accessible, and are published unaltered from the ori

This volume marks the beginning of hostilities between Britain and France. Although Franklin and his fellow commissioners do not play a major role in the new wartime diplomacy and military strategy,

Motivated by the remarkable fluidity of memory the way in which items are pulled spontaneously and effortlessly from our memory by vague similarities to what is currently occupying our attention "Spar

There is a universality about the creation of gardens across time and in diverse cultures that has inspired this entirely different garden book: a playful and affectionate typology of gardens; a patte

These essays appeared in the June 1988 Supplement of the American naturalist, v.131, and are based on papers of the 1986 Vice-Presidential Symposium of the American Society of Naturalists. Annotatio

In this classic text on the 18th century and neoclassicism, Jean Starobinski pursues a subtle and brilliant meditation on the connections between art and revolution, comparing the style of the French

Prediction and Classification: Criminal Justice Decision Making, a collection of commissioned essays by distinguished international scholars, is the ninth volume in the Crime and Justice series. Like

Dozens of books, articles, television shows, and films relating "near-death" experiences have appeared in the past decade. People who have survived a close brush with death reveal their extr