Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

The first comprehensive history of the Turkish economyThe population and economy of the area within the present-day borders of Turkey has consistently been among the largest in the developing world, y

How the legacy of monarchical empires shaped Britain, France, Spain, and the United States as they became liberal entitiesHistorians view the late eighteenth and early nineteenth centuries as a turnin

By early 1945, the war against Japan was at its height and General Douglas MacArthur began to fulfill his vow of liberating the Philippines. He was already planning his own victory parade down Dewey B

Set against the backdrop of the Age of Exploration, Black Flags, Blue Waters reveals the dramatic and surprising history of American piracy’s “Golden Age”—spanning the late 1600s through the early 170

Places that Matter asks the reader to identify a place that matters in their life—their home, a place of worship, a park, or some other site that acts as an emotional and physical anchor and con

Work hard in school, graduate from a top college, establish a high-paying professional career, enjoy the long-lasting reward of happiness. This is the American Dream—and yet basic questions at t

管理學宗師彼得·德魯克在人生最後一部作品中再次重申了卓越管理的三要素：做正確的事、用正確的人，以及建立正確的工作關係。作為德魯克在西北大學的嫡傳弟子，傑夫·斯瑪特將恩師的經驗進一步總結，提煉為實踐性更強的PWR公式：P（優先事項）×W（用人）×R（關係）。 斯瑪特在本書中列舉了skype、ebay、聯想、賽仕等世界級公司如何登頂為行業翹楚，也講述了名不見經傳的中小型企業如何通過提升團隊功率，實

A succinct and comprehensive history of the development of citizenship from the Roman Empire to the present dayCitizenship, Inequality, and Difference offers a concise and sweeping overview of citizen

The clerk attended desk and counter at the intersection of two great themes of modern historical experience: the development of capitalism and of a society governed from below. Who better illustrates

Mice are used as model organisms across a wide range of fields in science today—but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or

The success of any architectural project depends on the architect’s ability to depict it. Conveying architectural ideas as drawings, pictures, or models is both a critical part of the process and one that can tell us much about the design itself in a particular time or place. Over the past two decades, major new trends in architectural representation have emerged in Japan, which have gained widespread attention in the western world.Pictures of The Floating Microcosm considers these trends and takes readers through their development to the present day. Olivier Meystre undertakes a critique of the design tools and mediation techniques that have been employed and reveals the very special ways of conceiving an architectural project, drawing on a wealth of new research and interviews with contemporary Japanese architects. His book is a fascinating testimony of an entire generation of architects’ complex approach to a project, where all attributes of space are questioned and redefined while

When we talk about Presocratic philosophy, we are speaking about the origins of Greek philosophy and Western rationality itself. But what exactly does it mean to talk about "Presocratic philosophy" in

究竟是什麼原因使丹麥多次在聯合國發佈的《世界幸福報告》中位居魁首？ 丹麥父母又是怎樣教育出一代又一代快樂、自信、成功的孩子的？ 《跟丹麥父母學幸福教育》是一本構建幸福家庭的指導手冊。作者通過抽絲剝繭的分析，為我們提供了簡而有力的建議，尤其是六項丹麥教育的基本原則：P-A-R-E-N-T，即玩耍、誠實、重建、共情、不下通牒、愜意相聚――更能讓我們走出教育的樊籬，為孩子打開一扇通往幸福的大門。

Modern developed nations are rich and politically stable in part because their citizens are free to form organizations and have access to the relevant legal resources. Yet in spite of the advantages o

Nabokov's dream diary, published for the first time--and placed in biographical and literary contextOn October 14th, 1964, Vladimir Nabokov, a lifelong insomniac, began a curious experiment. Over the

Sovereign wealth funds (SWFs) have reached a transitional moment. Created as a way to direct excess wealth toward economic development and long-term financial returns, some countries are now seeing a

Sanitized Sex analyzes the development of new forms of regulation concerning prostitution, venereal disease, and intimacy during the American occupation of Japan after the Second World War, focusing o

A major new urban history of the design and development of postwar San FranciscoDesigning San Francisco is the untold story of the formative postwar decades when U.S. cities took their modern shape am

Galileo never set foot on the Iberian Peninsula, yet, as Enrique García Santo-Tomás unfolds in The Refracted Muse, the news of his work with telescopes brought him to surprising prominen

The Politics of Opera takes readers on a fascinating journey into the entwined development of opera and politics, from the Renaissance through the turn of the nineteenth century. What political backdr

Contrary to conventional wisdom, countries that ignite a process of rapid economic growth almost always do so while lacking what experts say are the essential preconditions for development, such as go

1938年狄漢馬丁牧師（M. R. De Haan）創立了RBC（Radio Bible Class Ministries）。目的是以此事工帶領世界各國的人們建立對基督的信仰和屬靈上的成熟度。本事工從美國底特律的一個小型廣播電台開始，從而成為許多人尋求聖經智慧的來源。後來又根據廣播的教導內容發行了《探索叢書》及每三個月出版一次的《靈命日糧》小冊，以贈送的方式提供給每一位有需要的人。1965年由狄漢

《哈佛教你精通大數據》瞄準目前已成「顯學」的「大數據」（Big Data），精選《哈佛商業評論》2012到2013年的八篇重量級相關文章。其中，有「知識管理大師」美譽的湯瑪斯．戴文波特（Thomas H. Davenport），更是本文集的最重要作者，共收錄了三篇他在《哈佛商業評論》發表的大作，其中包括分析工具的進階、決策方式的發展，甚至還詳解「資料科學家」這個即將成為企業不可或缺的重要職缺，將為

High-impact language for today’s lightning-fast world of salesFilled with practical writing tips, shortcuts, and examples, Power Sales Writing brings you up to date in a world where e-mail, social med

Navigating life's challenges on your own isn't just lonely, it is also counterproductive to personal growth and development. Whether you are looking to develop your leadership skills or to grow as a p

The Book of Common Prayer is the old and well-loved prayer book of the Church of England, in use since the 16th century. It has also become one of the classic English texts, its prayers and expressions helping to mould the English language into what it is today. Cambridge's new editions of the Prayer Book have been freshly typeset for the 21st century, using a modern digital typeface to give a clear printing image and greater readability. Nevertheless the format and page layout of this book follow the earlier Large-Print Edition Prayer Book page for page. It provides the complete 1662 services – including the traditional forms of the baptism and marriage services. The prayer book comes in a burgundy imitation leather hardback binding and will be helpful for anyone needing slightly larger print for ease of reading.

●為什麼“紅玫瑰”會變成“蚊子血”,當初的金童玉女 最終成了彼此冷眼相待的夫妻? ●為什麼在星期一激動人心的新工作，到了星期五就變得平淡無奇? ●為什麼許多人在步入中年後，覺得身邊的一切都失去了光彩，焦慮和抑鬱接踵而至? ●為什麼當初覺得無法忍受的事情，久而久之成了生活的常態，身處其中的人卻並不知情? “習慣化”源于人類的進化機制。為了生存，我們的大腦總是優先考慮新的、意想不到的東西，過濾掉老的、意料之中的東西。“習慣化”是一把雙刃劍，既幫助人類不斷適應新的環境，成功地生存和延續，又使人們如同溫水裡的青蛙， 逐漸適應惡化的情況，喪失行動力和競爭力，對即將到來的危險渾然不知 紐約心理學及神經學博士塔利·沙羅特、哈佛大學法學教接卡斯·R.桑斯坦結合心理學、神經科學、經濟學和哲學的成果與方法，深入研究了人類的習慣機制，展示了廣泛存在於會生活各個方面的“習慣化”和“去習慣化”現象。 在微觀層面，這本書幫助讀者更好地認識自己、認識生活，學會對好事珍惜、對壞事脫敏，擺脫倦怠感，重拾創造力。 在中觀層面，這本書為如何在商業環境中避免錯誤決策提供建議，探討企業如何通過靈活的變革保持活力，提升競爭力。 在宏觀層面，這本書帶領讀者重新審視各類社會議題，如健康與安全、風險與不確定性、全球環境、結構性問題等等，為思考這些議題提供了啟發性的觀點和視角。

《明心寶鑑》抄譯本收藏於西班牙馬德里國家圖書館，此書是十四世紀以來流行於東亞各地的書籍，為童蒙用書與善書，內容抄撮各種書籍中的嘉言警語，作為修身、行世之用。十六世紀下半葉閩南人至馬尼拉經商、住居，亦將此類日用書籍帶至馬尼拉。《明心寶鑑》抄譯本由西班牙道明會傳教士嗃呣𠿢（Juan Cobo）與馬尼拉唐人合作抄譯，約完成於1590年前後，具體呈現大航海時代閩南人與西班牙語世界的交流過程與成果，為人類「世界記憶」（Memory of the World）的重要資產。The translated transcription of the Beng Sim Po Cam was a collection of the Biblioteca Nacional de España in Madrid. A popular book that had been circulating in East Asia since the fourteenth century, it was used for children's enlightenment and moral guidance. It collected proverbs and warnings from various texts which were meant to cultivate moral character and advise on choices in life. When Hokkien people arrived in Manila in late sixteenth century for trade and settlement, they also brought books of daily use like this one to Manila. The translated transcription of the Beng Sim Po Cam was transcribed by Spanish Dominican missionary Juan Cobo with help from Chinese in Manila. It was completed around 1590, and it definitely presented the process and achi

Everything You Need to Ace American History in One Big Fat Notebook學霸筆記：美國史Everything You Need to Ace Biology in One Big Fat Notebook學霸筆記：生物Everything You Need to Ace Chemistry in One Big Fat Notebook學霸筆記：化學Everything You Need to Ace Computer Science and Coding in One Big Fat Notebook學霸筆記：電腦與編碼Everything You Need to Ace English Language Arts in One Big Fat Notebook學霸筆記：語言學習－英文Everything You Need to Ace Geometry in One Big Fat Notebook學霸筆記：幾何學Everything You Need to Ace Math in One Big Fat Notebook學霸筆記：數學9781523504381Everything You Need to Ace Pre-Algebra and Algebra I in One Big Fat Notebook學霸筆記：代數9780761160953Everything You Need to Ace Science in One Big Fat Notebook學霸筆記：科學9780761160946Everything You Need to Ace World History in One Big Fat Notebook學霸筆記：世界史9781523513581The Big Fat Middle School Math Workbook－Studying with the Smartest Kid in Class學霸筆記：數學練習冊

The Roman army was the greatest fighting machine in the ancient world. More than that, it was the single largest organization in Western antiquity, taking in members from all classes, from senators to

Intellectuals "have been both rallying points and railed against in American politics, vessels of hope and targets of scorn," writes Michael J. Brown as he invigorates a recurrent debate in American l

States of Exception in American History brings to light the remarkable number of instances since the Founding in which the protections of the Constitution have been overridden, held in abeyance, or de

In the autumn of 1938, Europe believed in the promise of peace. But only a year later, the fateful decisions of just a few men had again led Europe to a massive world war. Drawing on contemporary diar

A monumental exploration of soccer and society in our time—by its preeminent historian.In the twenty-first century, soccer commands the allegiance, interest, and engagement of more people in more plac