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Modeling Dose-Response Microarray Data in Early Drug Development Experiments Using R

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Statistical Methods For Dose-Finding Experiments
90 折
出版日:2006/04/13 作者:Chevret  出版社:John Wiley & Sons Inc  裝訂:精裝
Dose-finding experiments define the safe dosage of a drug in development, in terms of the quantity given to a patient. Statistical methods play a crucial role in identifying optimal dosage. Used appro
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Exposure-response Modeling ― Methods and Practical Implementation
90 折
出版日:2015/07/29 作者:Jixian Wang  出版社:Taylor & Francis  裝訂:精裝
Discover the Latest Statistical Approaches for Modeling Exposure-Response RelationshipsWritten by an applied statistician with extensive practical experience in drug development,Exposure-Response Mode
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The Wizard's Guide to Magical Experiments:40 science experiments to try at home
滿額折
出版日:2025/09/11 作者:Amanda Wood; Jo Jo Rioux  出版社:Magic Cat Publishing  裝訂:精裝
The Wizard's Guides to Magical Experiments sparks wonder and curiosity with 40 engaging real-life science experiments for wizards-in-training to try at home. Welcome to the Touchwood Academy of Magical Thinking, where magical abilities are a must. Kids will discover the thrill of the real-life magic of chemistry with hands-on experiments from the creator of the bestselling Ology books, A.J.Wood. As a "First Class Wizard," Wood guides wizards-in-training through dozens of magic tricks and spells that are actually wow-inducing age-appropriate science experiments. Mini-booklets and fold-out activities on every page add to the excitement and discovery, covering topics such as:- what is the world made of?- experiments with water- magical matter- magical mixtures- the importance of energy- experiments with air- experiments with salt- the magic of crystals- the acid test- experiments with vinegar- reactions and transformations- kitchen alchemyYoung wizards will stop water from freezing, make
優惠價: 79 869
庫存:5
Home Activity Lab: Exciting Experiments for Budding Scientists
滿額折
出版日:2024/01/16 作者:Winston; Robert  出版社:DK US  裝訂:精裝
This jam-packed collection of fun and simple science experiments for kids is perfect for the classroom or home. Stir up some sticky slime, build a solar system with rubber bands, power a speed boat using soap, and construct an erupting volcano, all with Home Activity Lab, which offers exciting experiments for budding scientists. Including a foreword by Professor Robert Winston, this stunning book includes 28 brilliant science projects using simple step-by-step instructions, everyday ingredients that can be found around the house, and amazing photography to guide you from start to finish. Each experiment describes the science behind the project, highlighting STEM facts with STEM icons pointing out the key science, technology, engineering, and math learning involved in each project. "Take it further" panels encourage young readers to experiment and take their projects to the next level, developing their independence, initiative, and creative thinking skills. Perfect for budding scientist
優惠價: 79 600
庫存:1
Batch Effects And Noise In Microarray Experiments - Sources And Solutions
90 折
出版日:2009/10/28 作者:Scherer  出版社:John Wiley & Sons Inc  裝訂:精裝
Batch Effects and Noise in Microarray Experiments: Sources and Solutions looks at the issue of technical noise and batch effects in microarray studies and illustrates how to alleviate such factors whi
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科瑞‧R.塔博的創意翻轉繪本(共三冊)
滿額折
出版日:2024/11/05 作者:科瑞.R. 塔博-著; 柯倩華-譯; 科瑞.R. 塔博-繪  出版社:三民書局  裝訂:精裝
美國凱迪克大獎、Openbook年度童書得主科瑞.R. 塔博震撼新作跟著翠鳥翠翠、小狗賽門和鯰魚小漁,探索橫跨陸海空的生態小宇宙!~~~內容簡介~~~《翠翠掉下去了!》有一天,媽媽不在家,翠鳥翠翠決定開始學飛!即使很害怕,翠翠可不讓恐懼阻撓她學飛的決心。沒想到,她……掉下去了!翠翠能夠扭轉墜落之勢,成功振翅高飛嗎?《更棒的骨頭》小狗賽門叼著一根骨頭來到池塘邊,遇到了一隻長得一模一樣的狗狗。只是他嘴裡叼著的骨頭,比自己的「更棒」!賽門用盡各種方法,企圖想跟水裡的狗交換骨頭:大眼瞪小眼比賽、追尾巴比賽…… 軟硬兼施卻都換不來那根「更棒的」骨頭。究竟小狗賽門怎樣才能交換成功呢?《小漁顛倒游》小漁是一隻快樂的鯰魚,生活在美好的水底世界。水上有各樣的水草搖曳舞動,水下有湛藍的天空和蟲蟲大餐。可是一場交談,令小漁發現了一個天大的祕密……她竟然顛倒了?~~~套書特色~~~►超人氣的互動翻頁設計,身歷其境主角們的酸甜苦辣◄ 來吧來吧!展開雙翅跟著翠翠學習飛翔,與狗狗賽門比賽大眼瞪小眼,也和小漁一起體會180度的翻轉泳姿。科瑞.R. 塔博利用實體書本的開頁,結合天馬行空的轉書創意,打造前所未有的閱讀體驗!►清新自然的風格,刻畫出寓意十足的陸海空小宇宙◄ 作者透過童趣的蠟筆和柔美的水彩筆觸,不只將角色們表現得活靈活現,還期許孩子擁有追夢的勇氣,懂得分享且有同理心,並在面對外界質疑時保有自身的獨特性。
優惠:2026國際書展-單79三75 優惠價: 79 845
庫存 > 10
Personal Data (Privacy) Law in Hong Kong: A Practical Guide on Compliance (Third Edition)
滿額折
出版日:2024/08/01 作者:Ada CHUNG Lai-ling & Guobin ZHU  出版社:香港城市大學出版社  裝訂:精裝
With an increasing concern of personal data privacy in Hong Kong and around the world, the Office of the Privacy Commissioner for Personal Data (PCPD), Hong Kong publishes this third edition of Personal Data (Privacy) Law in Hong Kong: A Practical Guide on Compliance to provide practical guidance on the law of privacy, and the ways to protect personal data in everyday life.This third edition will guide readers through the recent developments of personal data privacy in the local, regional and global contexts with updates on recent Administrative Appeals Board and Court decisions, and investigation reports and materials from the PCPD. In addition, some most-concerned issues are discussed, such as ethical development and use of AI, the collection and use of personal data by employers during COVID-19, data protection under work-from-home arrangements, data security measures for ICT systems, guidelines on doxxing offences and data breach handling. This book will certainly provide readers a
優惠:城市大學書展 優惠價: 79 2844
庫存 > 10
Hypocrisy:The Tales and Realities of Drug Detainees in China
滿額折
出版日:2019/06/13 作者:Vincent Shing Cheng  出版社:香港大學出版社  裝訂:精裝
Although the official propaganda surrounding the drug detainees in China is that of helping, educating, and saving them from their drug habits and the drug dealers who lure them into drug abuse, it is
優惠:香港大學書展 優惠價: 79 1248
庫存:2
Integrating Omics Data
90 折
出版日:2015/05/31 作者:George Tseng  出版社:Cambridge Univ Pr  裝訂:精裝
In most modern biomedical research projects, application of high-throughput genomic, proteomic, and transcriptomic experiments has gradually become an inevitable component. Popular technologies include microarray, next generation sequencing, mass spectrometry and proteomics assays. As the technologies have become mature and the price affordable, omics data are rapidly generated, and the problem of information integration and modeling of multi-lab and/or multi-omics data is becoming a growing one in the bioinformatics field. This book provides comprehensive coverage of these topics and will have a long-lasting impact on this evolving subject. Each chapter, written by a leader in the field, introduces state-of-the-art methods to handle information integration, experimental data, and database problems of omics data.
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Regression With Social Data: Modeling Continuous And Limited Response Variables
90 折
出版日:2004/08/27 作者:Demaris  出版社:John Wiley & Sons Inc  裝訂:精裝
An accessible introduction to the use of regression analysis in the social sciencesRegression with Social Data: Modeling Continuous and Limited Response Variables represents the most complete and full
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J. R. R. Tolkien (美國版)(精裝本)
滿額折
出版日:2022/04/05 作者:Maria Isabel Sanchez Vegara  出版社:Frances Lincoln Childrens Books  裝訂:精裝
繼電影《魔戒三部曲》之後,亞馬遜重啟開拍全新影集。透過《小人物大夢想》繪本認識這部奇幻史詩的作者J. R. R.托爾金。從南非搬到英國大城市,受困於水泥叢林進而使想像力的種子萌芽,成為當代奇幻文壇巨擘。In this book from the highly acclaimed Little People, BIG DREAMS series, discover the incredible life of J. R. R. Tolkien, author and forefather of the fantasy genre. Little John experienced lots of change in his life from a young age. Moving from South Africa to a big city in England, he longed for the nature he grew up around. After the death of both of his parents, John found comfort in telling stories and building imaginary worlds with his friends. And he continued to tell stories for the rest of his life, creating epic tales of hobbits, dwarves, elves, and wizards as J. R. R. Tolkien. This inspiring book features stylish and quirky illustrations and extra facts at the back, including a biographical timeline with historical photos and a detailed profile of the writer's life. Little People, BIG DREAMS is a bestselling series of books and educational games that explore the lives of ou
優惠價: 79 480
庫存:2
Philosophy for Beginners (精裝本)
滿額折
出版日:2020/05/28 作者:Nick Radford  出版社:Usborne UK  裝訂:精裝
Philosophy is a way of thinking about just about anything. It asks big questions from nature of reality to what beauty is. Using lively examples and thought experiments, this book provides an accessib
優惠:外文國際書展-單本399六本1999 優惠價: 73 399
庫存:1
Data Science and Analytics With Python
75 折
出版日:2017/05/16 作者:Jesus Rogel-salazar  出版社:Chapman & Hall  裝訂:精裝
Data Science and Analytics with Python is designed for practitioners in data science and data analytics in both academic and business environments. The aim is to present the reader with the main conce
優惠:Taylor and Francis 書展 優惠價: 75 4950
庫存:1
Sociology and Anthropology in Twentieth-Century China:Between Universalism and Indigenism 中國社會學與人類學
滿額折
出版日:2012/03/01 作者:DIRLIK; Arif; LI; Guannan & YEN; Hsiao-pei  出版社:香港中文大學出版社  裝訂:精裝
Within this text, the contributors provide a historical perspective on the development of anthropology and sociology since their introduction to Chinese thought and education in the early twentieth ce
優惠:香港中文大學書展 優惠價: 79 1232
庫存:2
Zhao Mengfu:Calligraphy and Painting for Khubilai's China
滿額折
出版日:2011/04/01 作者:SHANE MCCAUSLAND  出版社:香港大學出版社  裝訂:精裝
Zhao Mengfu has enormous significance for Chinese art history. This work presents a new, synthetic portrait of the artist's development from the 1280s to his death in 1322, and evaluates his pivotal r
優惠:香港大學書展 優惠價: 79 1248
庫存:1
A Brighter Side: Protective and Risk Factors in the Rehabilitation of Chronic Drug Abusers in Hong Kong
滿額折
出版日:2009/03/01 作者:CHEUNG; Yuet Wah  出版社:香港中文大學出版社  裝訂:精裝
Despite the increase of research investigating various aspects of the drug problem in Hong Kong in the past decade, little was known about the pathway to continuous drug use or recovery of chronic dru
優惠:香港中文大學書展 優惠價: 79 703
庫存:2
Handbook for Applied Modeling ─ Non-Gaussian and Correlated Data
90 折
出版日:2017/07/31 作者:Jamie D. Riggs  出版社:Cambridge Univ Pr  裝訂:精裝
Designed for the applied practitioner, this book is a compact, entry-level guide to modeling and analyzing non-Gaussian and correlated data. Many practitioners work with data that fail the assumptions of the common linear regression models, necessitating more advanced modeling techniques. This Handbook presents clearly explained modeling options for such situations, along with extensive example data analyses. The book explains core models such as logistic regression, count regression, longitudinal regression, survival analysis, and structural equation modelling without relying on mathematical derivations. All data analyses are performed on real and publicly available data sets, which are revisited multiple times to show differing results using various modeling options. Common pitfalls, data issues, and interpretation of model results are also addressed. Programs in both R and SAS are made available for all results presented in the text so that readers can emulate and adapt analyses for
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Analyzing Financial Data and Implementing Financial Models Using R
90 折
出版日:2015/04/14 作者:Clifford S. Ang  出版社:Springer Verlag  裝訂:精裝
This book is a comprehensive introduction to financial modeling that teaches advanced undergraduate and graduate students in finance and economics how to use R to analyze financial data and implement
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Modeling Atmospheric And Oceanic Fluid Flow: Insights From Laboratory Experiments And Numerical Simulations
90 折
出版日:2014/11/14 作者:Von Larcher  出版社:John Wiley & Sons Inc  裝訂:精裝
Modeling Atmospheric and Oceanic Flows: Insights from Laboratory Experiments and Numerical Simulations provides a broad overview of recent progress in using laboratory experiments and numerical simula
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Modeling Count Data
90 折
出版日:2014/06/30 作者:Joseph M. Hilbe  出版社:Cambridge Univ Pr  裝訂:精裝
This entry-level text offers clear and concise guidelines on how to select, construct, interpret, and evaluate count data. Written for researchers with little or no background in advanced statistics, the book presents treatments of all major models using numerous tables, insets, and detailed modeling suggestions. It begins by demonstrating the fundamentals of modeling count data, including a thorough presentation of the Poisson model. It then works up to an analysis of the problem of overdispersion and of the negative binomial model, and finally to the many variations that can be made to the base count models. Examples in Stata, R, and SAS code enable readers to adapt models for their own purposes, making the text an ideal resource for researchers working in health, ecology, econometrics, transportation, and other fields.
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Data-Driven Modeling ― Using Matlab in Water Resources and Environmental Engineering
90 折
出版日:2013/11/30 作者:Shahab Araghinejad  出版社:Springer Verlag  裝訂:精裝
“Data-Driven Modeling: Using MATLABR in Water Resources and Environmental Engineering” provides a systematic account of major concepts and methodologies for data-driven models and presents a unified f
優惠價: 9 3375
無庫存
出版日:2013/04/03 作者:Tshilidzi Marwala  出版社:Springer-Verlag New York Inc  裝訂:精裝
Economic Modeling Using Artificial Intelligence Methods examines the application of artificial intelligence methods to model economic data. Traditionally, economic modeling has been modeled in the lin
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
Spatial Data Analysis in Ecology and Agriculture Using R
90 折
出版日:2012/03/09 作者:Richard E. Plant  出版社:CRC Press UK  裝訂:精裝
Assuming no prior knowledge of R, Spatial Data Analysis in Ecology and Agriculture Using R provides practical instruction on the use of the R programming language to analyze spatial data arising from
優惠價: 9 3392
無庫存
Early Drug Development: Strategies And Routes To First-In-Human Trials
90 折
出版日:2010/06/24 作者:Cayen  出版社:John Wiley & Sons Inc  裝訂:精裝
The focus of early drug development has been the submission of an Investigational New Drug application to regulatory agencies. Early Drug Development: Strategies and Routes to First-in-Human Trials gu
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出版日:2010/03/30 作者:Sridar V. Chittur (EDT)  出版社:Springer Verlag  裝訂:精裝
While the utilization of microarrays for gene expression studies has been widely published, Microarray Methods for Drug Discovery describes the use of this technology for a multitude of other vital ap
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
Uncertainty Modeling In Dose Response: Bench Testing Environmental Toxicity
90 折
出版日:2009/06/23 作者:Cooke  出版社:John Wiley & Sons Inc  裝訂:精裝
A valuable guide to understanding the problem of quantifying uncertainty in dose response relations for toxic substances In today's scientific research, there exists the need to address the topic of
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出版日:2007/05/03 作者:Michael J. Korenberg  出版社:Humana Pr Inc  裝訂:精裝
In this new volume, renowned authors contribute fascinating, cutting-edge insights into microarray data analysis. Information on an array of topics is included in this innovative book including in-dep
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Dose Optimization in Drug Development
90 折
出版日:2006/05/01 作者:Edited by Rajesh Krishna  出版社:CRC Press UK  裝訂:精裝
This reference provides a concise overview of the key principles in dose selection and optimization and demonstrates applicability to recent successful new drug applications. Compiling key issues and
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小漁顛倒游
滿額折
出版日:2024/11/06 作者:科瑞.R. 塔博-著; 柯倩華-譯; 科瑞.R. 塔博-繪  出版社:小山丘  裝訂:精裝
美國凱迪克大獎、Openbook 「年度童書」多項大獎《翠翠掉下去了!》作者—科瑞.R. 塔博最新作!世界顛倒不顛倒,誰說的算?一場邂逅讓小漁的世界整個翻轉了,迷失方向的她,能夠再度找回自信心嗎?小漁是一隻快樂的鯰魚,生活在美好的水底世界。水上有各樣的水草搖曳舞動,水下有湛藍的天空和蟲蟲大餐。可是一場交談,令小漁發現了一個天大的祕密…… 她竟然顛倒了?~~~~本書特色~~~~✦建立信心,愛上自己的獨特曾幾何時孩子不再為自身的獨特歡呼了?反而是開始在群體中低調合群,不要太突出或是表現自我,不喜歡不一樣,或者害怕他人詫異的眼光。此書透過小漁對「不一樣」的自我探索,建立孩子的自信與勇氣,並鼓勵他們活出屬於每個人最獨特的模樣。畢竟,誰說世界一定就是什麼樣子呢?最獨一無二的想法才是大家最想聽見的呢。✦180度互動式的翻頁設計,感同身受小漁的水中奇遇作者精心設計的翻頁動線,讓讀者將手中繪本進行兩次180度的大翻轉,除了身歷其境主角小漁的視角,感受周遭環境翻轉的震撼,也象徵著小漁從迷惘到頓悟的心境變化。全書採用小漁的視角呈現,而陽光、空氣、河水顛倒的構圖設計,也讓小小讀者開始好奇「如果換個角度看,世界會有什麼新的可能性呢?」✦認識非洲剛果河流域的鯰魚習性,發現大自然的奧秘繼翠鳥翠翠和小狗賽門以後,科瑞 R. 塔博的第一本水底作品。活潑逗趣的畫風配上暖心的故事劇情,帶讀者認識黑腹歧鬚鮠(小漁)顛倒著游泳的習性,進而激發孩子對自然生態的好奇心與興趣。*有注音*推薦閱讀年齡:3歲~7歲親子共讀、7歲以上可自行閱讀。
優惠:2026國際書展-單79三75 優惠價: 79 292
庫存 > 10
Simon and the Better Bone
滿額折
出版日:2023/05/09 作者:Corey R. Tabor  出版社:Balzer & Bray  裝訂:精裝
Using the same innovative format as his Caldecott Honor winner, Mel Fell, Corey R. Tabor reimagines Aesop’s “The Dog and His Reflection” in a clever, charming tale of empathy and generosity.One day, down by the pond, Simon meets another dog just like him.And that dog has a bone just like his, only better!How will Simon ever get him to trade, when the other pup knows all the same tricks...?This is another delightfully surprising tale from the award-winning creator of Mel Fell.
優惠價: 79 600
庫存:6
Busy Little Hands: Science Play: Learning Activities for Preschoolers
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出版日:2022/12/20 作者:Susan Edwards Richmond  出版社:Storey Books  裝訂:精裝
Preschoolers are introduced to core science concepts with this playful format featuring 20 hands-on activities that use everyday household materials, including a vinegar volcano, a hula hoop count, and a kitchen sink or swim experiment. In this fourth book in the Busy Little Hands series, preschoolers get ready for a science adventure! Preschoolers wonder and explore with 20 hands-on experiments using everyday household objects and making daily activities such as snack time and play time into learning opportunities. Each play activity demonstrates a simple principle of physics, earth science, chemistry, or biology, including the Kitchen Sink or Float (demonstrating density), the Vinegar Volcano (pressure) and Blooming Colors (chromatography). Featuring bright, easy-to-follow photos specially designed for pre-readers, this book is packed with learning fun, plus it sets the groundwork for science success in kindergarten and beyond.
優惠價: 79 390
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Lego(r) Iconic: Advent Calendar (降臨曆)
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出版日:2021/09/14 作者:Ameet Publishing  出版社:Studio Fun Intl  裝訂:精裝
53*36cm。以樂高人物為主角的活動書,有超過300個活動,讓小朋友腦力激盪。Join in the LEGO(R) Iconic Christmas countdown with 24 mini books to get you in the holiday spirit Let your imagination run wild as you countdown to Christmas with this advent calendar full of exciting and engaging activities Kids get one new mini winter LEGO(R) title for each day leading up to Christmas, and with 24 activity books in all, this holiday season is sure to be fun LEGO, the LEGO logo and the Brick and Knob configurations are trademarks and/or copyrights of the LEGO Group. (c)2021 The LEGO Group. All rights reserved.Manufactured by AMEET Sp. z o.o. under license from the LEGO Group.
優惠:外文新書66折 優惠價: 66 627
庫存:10
An Introduction To Categorical Data Analysis, 3Rd Edition
75 折
出版日:2018/11/05 作者:Agresti  出版社:John Wiley & Sons Inc  裝訂:精裝
A valuable new edition of a standard referenceThe use of statistical methods for categorical data has increased dramatically, particularly for applications in the biomedical and social sciences. An In
優惠:John Wiley 書展 優惠價: 75 7152
庫存:1
International Perspectives on Early Childhood Education and Care ─ Early Childhood Education in the 21st Century
75 折
出版日:2018/01/24 作者:Susanne Garvis (EDT); Sivanes Phillipson (EDT); Heidi Harju-luukkainen (EDT)  出版社:Routledge  裝訂:精裝
The first volume in this Early Childhood Education and Care in the 21st Century: International Teaching, Family and Policy Perspectives miniseries provides a snapshot of early childhood education and
優惠:Taylor and Francis 書展 優惠價: 75 7200
庫存:1
Data Science Using Python And R
90 折
出版日:2019/03/22 作者:Larose  出版社:John Wiley & Sons Inc  裝訂:精裝
Learn data science by doing data science! Data Science Using Python and R will get you plugged into the world’s two most widespread open-source platforms for data science: Python and R.Data scien
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
Panel Data Econometrics With R
90 折
出版日:2018/08/29 作者:Croissant  出版社:John Wiley & Sons Inc  裝訂:精裝
Panel Data Econometrics with R provides a tutorial for using R in the field of panel data econometrics. Illustrated throughout with examples in econometrics, political science, agriculture and epidemi
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
A Data Scientist'S Guide To Acquiring, Cleaning And Managing Data In R
滿額折
出版日:2017/10/16 作者:Buttrey  出版社:John Wiley & Sons Inc  裝訂:精裝
The only how-to guide offering a unified, systemic approach to acquiring, cleaning, and managing data in R Every experienced practitioner knows that preparing data for modeling is a painstaking, time-
優惠價: 9 3179
無庫存
出版日:2017/01/06 作者:Rui Sarmento; Vera Costa  出版社:Information Science Reference  裝訂:精裝
For readers who may not be statisticians or data analysts, Sarmento and Costa explain how to analyze data using the Python and R languages. They have particularly in mind, students and researchers
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
出版日:2016/04/06 作者:Pietro Hiram Guzzi (EDT)  出版社:Humana Pr Inc  裝訂:精裝
This volume covers a large area, from the description of methodologies for data analysis to the real application. Chapters focus on methodologies for preprocessing of microarray data, a survey of miRN
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
Mass Spectrometry For Drug Discovery And Drug Development
90 折
出版日:2013/01/18 作者:Korfmacher  出版社:John Wiley & Sons Inc  裝訂:精裝
This book presents a summary of the ways mass spectrometry is used in various stages of drug discovery and development including early support of medicinal chemistry, drug metabolism studies, distribu
若需訂購本書,請電洽客服 02-25006600[分機130、131]。
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